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All Journal Jurnal Keperawatan Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Jurnal Kedokteran Brawijaya Prosiding Seminas Competitive Advantage Wacana, Jurnal Sosial dan Humaniora Indonesian Journal of Disability Studies Research Journal of Life Science MNJ (Malang Neurology Journal) Universa Medicina Majalah Kesehatan FKUB BIMIKI (Berkala Ilmiah Mahasiswa Ilmu Keperawatan Indonesia) JSMARTech : Journal of Smart Bioprospecting and Technology Az-Zahra: Journal of Gender and Family Studies Pharmaceutical Sciences and Research (PSR) Jurnal Ners dan Kebidanan (Journal of Ners and Midwifery)
Retty Ratnawati
Faculty of Medicine, Brawijaya University, Jl. Veteran, Malang
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Journal : MNJ (Malang Neurology Journal)

 1 
EFFECT ANTHOCYANIN OF PURPLE POTATO GUNUNG KAWI ON MDA LEVELS, EXPRESSION OF CASPASE-3, AND SPATIAL MEMORY FUNCTION ON DIABETIC WISTAR RATS Prabawati, Risma Karlina; Ratnawati, Retty; Rahayu, Masruroh; Prakosa, Ardani Galih
Malang Neurology Journal Vol 5, No 1 (2019): January
Publisher : Malang Neurology Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2019.005.01.6

Abstract

Background: Hyperglycemia condition will decline cognitive function. No basic therapy has been 2 found for this. Purple potato anthocyanins are useful as anti-inflammatory, antioxidant, neuroprotectant, and antidiabetic.Objective: Evaluate effect of purple potato’s anthocyanins on MDA levels, brain’s caspase-3 expressiom, and spatial memory function in diabetic model of Wistar rats.Methods: This is an experimental study using diabetic model rats. The sample was divided into negative and positive control, anthocyanin dose of 10 mg/kg, 20 mg/kg, and 80 mg/kg groups. MDA levels were measured using spectrophotometer, caspase-3 expression with immunohistochemistry, and spatial memory function using Morris water maze test.Results: Tukey test showed that anthocyanin 10, 20, and 80 mg/kg lowering MDA levels, caspase-3 expression, and Morris water maze’s travel time compared to control positive (p = 0.000). But anthocyanin 80 mg/kg make a significant increase on these three variabels compared to 10 and 20mg/kg groups (p = 0.010). Pearson test showed that there no correlation between anthocyanin’s dose, MDA levels, caspase-3 expression, and Morris water maze test.Conclusion: Anthocyanin doses 10 and 20 mg/kg lowering MDA levels and caspase-3 expression, also improves spatial memory function on diabetic model of Wistar rats.
DEPRESSION AND INTERNET GAMING DISORDER AMONG MEDICAL STUDENT IN MALANG, INDONESIA Kurnianingsih, Nia; Cahayani, Wike Astrid; Yudhantara, Dearisa Surya; Ratnawati, Retty
MNJ (Malang Neurology Journal) Vol. 11 No. 1 (2025): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2025.011.01.08

Abstract

Background: Medical education is widely regarded as a highly demanding curriculum that causes significant stress among students. Chronis stress generates depression and increase of internet gaming activity. Previous research examined the relationship between the length of time spent for internet gaming activity as well as grade point average (GPA) towards internet gaming disorder (IGD) among medical student in Malang Indonesia. The limited data on the frequency of depression and the association between depression with IGD among medical students calls for more research. Objectives: This study was purposed to analyse the prevalence of depression as well as its association with IGD among medical students in Malang, Indonesia. Methods: This descriptive and cross-sectional study involved 437 medical students who completed a set of self-report questionnaires. The questionnaires included sociodemographic data, Beck Depression Inventory (BDI) scale and Personal Internet Gaming Disorder-9 (PIE-). Descriptive and bivariate analyses were employed for statistical analysis. Results: Depression was identified among 37.99% students, with female being more likely to suffer from it. There were 59.64%, 34.94% and 5.42% correspondingly of students with mild, moderate, and severe depression. The rate of depression was highest among 1st year students. Poor GPA achievement was observed in 50.98% of students with depression. Students without internal motivation were more likely to have depression (57.14%). Surprisingly, depression was not linked associated with IGD (p=0.06). Conclusion: This study concluded a high prevalence of depression among medical students with various sociodemographic characteristics. Despite depression had no association with IGD, future research is necessary for evaluate the potential risk factor of depression among medical students.
Co-Authors A.A. Ketut Agung Cahyawan W AA Sudharmawan, AA Almira, Nabila Sella Anak Agung Gede Sugianthara Analis W Wardhana Anastasia Novitasari, Anastasia Annisa Nurul Arofah Annisa' Wigati Rozifa Ardani Galih Prakosa, Ardani Galih Artamevia, Dian Arum Desi Pratiwi, Arum Desi Atma Gunawan Aulanni'am, Aulanni'am Cahayani, Wike Astrid Christian Julio Suhardi, Christian Julio Darwatik, Darwatik Dian Hasanah Dian Susmarini, Dian Diana Lyrawati Dina Dewi SLI Eviana Norahmawati Fahanani, Agwin Fahmi Faridha Khaira H Fauzi Ahmad Muda Ferdina, Cucun Setya Harbiyanti, Novita Titis HARI PURNOMO Heri Kristianto Herin Mawarti Hery Wibowo Hidayat Sujuti Ika Subekti Wulandari, Ika Subekti Ikhda Ulya, Ikhda Inggita Kusumastuty Intan Berlian, Intan Irawan, Dwi Dianita Kenty Wantri Anita, Kenty Wantri Kumboyono Kumboyono Kumboyono, K Kurnianingsih, Nia Lilik Supriyati, Lilik Lilik Wahyuni Lisa Aulia, Lisa Made Ayu Hariningsih, Made Ayu Masruroh Rahayu, Masruroh Mochammad Dalhar Noorma Lukitasari Nur Permatasari Nurdiana Nurdiana Pratista Adi Krisna, Pratista Adi Prayogo, Nabila Putri Purwitasari, Alief Ayu Rahma, Oktivani Adelathifa Rayhanna, Qanitha Ailsya Reza Fitra Kusuma, Reza Fitra Rinik Eko Kapti, Rinik Ririn Handayani Risma Karlina Prabawati Sartika Dewi Utami, Sartika Dewi Sarwono . Sawitri, Lia Siti Nurfitria, Siti Sri Andarini Sri Budhi Rianawati, Sri Budhi Sri Haryuni Sri Rianawati Suprapto, Ratih Paramita Tinny Endang Hernowati Titisari, Nurina Wike Wike, Wike Wiwi Jaya Yudhantara, Dearisa Surya