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Maternal, Obstetric, and Infant Factors and Their Associatio with the Risk of HIV Infection in Infants at Dr. Moewardi Hospital, Surakarta Rahmawati, Deni Nur Fauzia; Respati, Supriyadi Hari; Hanim, Diffah
Journal of Maternal and Child Health Vol 1, No 2 (2016)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Incidence of HIV infection by mother to child transmission has been increasing for the past few years. This study aimed to determine the association between maternal, obstetric, infant factors, and the risk of HIV infection in infant.Subjects and Method: This was an analytic observational study using case control design. This study was conducted at Dr. Moewardi Hospital, Surakarta. A total of 68 study subjects, consisting of 34 HIV infected infants, and 34 non HIV infected infants, were selected for this study by fixed disease sampling. The dependent variable was HIV infection. The independent variable included maternal nutrirional status, opportunistic infection, antenatal care, type of labor, birth weight, and prematurity. The data were collected by a set of questionnaire and analyzed using logistic regression model.Results: Maternal HIV opportunistic infection (OR= 10.09; 95% CI= 1.99 to 51.20; p=0.005) and pervaginam labor (OR=5.21; 95% CI=0.92 to 29.58; p=0.063) increase the risk of HIV infection in infant, and they were statistically significant. Maternal body weight (BMI<18.5)(OR=2.71; 95% CI=0.44 to 16.53; p=0.280), antenatal care <4 times (OR=1.94; 95% CI= 0.42 to 9.00; p=0.395), birth weight <2.500 gram (OR=1.09; 95%CI=0.19 to 6.05;p=0.924) and prematurity (OR= 1.65; 95% CI=0.36 to 7.61; p=0.523), each increased the risk of HIV infection but statistically non-significant.Conclusion: Maternal HIV opportunistic infection and pervaginam labor are strong and significant predictors for the risk of infant HIV infection. Health personnel should pay special attention on these significant risk factors when assisting birth delivery, in order to prevent HIV infection in infants.Keywords: maternal, obstetric, infant risk factors, HIV infection.Correspondences: Deni Nur Fauzia Rahmawati. Masters of Public  Health Program, Sebelas Maret University. Email: denierahmawati@gmail.comJournal Maternal  and Child Health (2016), 1(2): 73-82https://doi.org/10.26911/thejmch.2016.01.02.02
KADAR HUMAN LEUKOCYTE ANTIGEN-G (HLAG) DAN TUMOR NERCROSIS FAKTOR ALPHA (TNF-a) PADA ABORTUS DAN KEHAMILAN NORMAL Adhi, Kresno Condro; Sulistywati, Sri; Respati, Supriyadi Hari
JURNAL KESEHATAN REPRODUKSI Vol 2, No 2 (2015)
Publisher : Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (378.609 KB) | DOI: 10.22146/jkr.12638

Abstract

KADAR HUMAN LEUKOCYTE ANTIGEN-G (HLAG) DAN TUMOR NERCROSIS FAKTOR ALPHA (TNF-a) PADA ABORTUS DAN KEHAMILAN NORMALKresno Condro Adhi1, Sri Sulistyowati2, Supriyadi Hari Respati3ABSTRACTBackground: Abortion is one of the causes of maternal morbidity and mortality. Rejection of the fetusdue to recognition of paternal antigens by the maternal immune system, is suspected to be a cause ofunexplained pregnancy loss. Human Leukocyte Antigen G (HLA-G) expressed by thropoblast and TumorNecrosis Factor α (TNF-α) suspected as one of important inflammatory mediators associated with abortion.Objective : To analyze levels of the HLA-G and TNF-α in the serum of abortion and normal pregnancy.Method: Observational analytic with Cross sectional approach at the Obstetric and Gynecology DepartmentDr. Moewardi hospital Surakarta and Prodia laboratory since August - November 2014. Number of samplestudied was 40 sample divided into 2 groups, 20 sample abortion and 20 sample normal pregnancy. Allthe sample were examined the HLA-G and TNF-α serum level by ELISA method and analyze by t test withCI 95%.Result and Discussion: Average value of HLA-G in abortion group was 55,0246±26,01 ng/ml and normalpregnancy group with an average 76,7200±32,18 ng/ml with p=0,024 (p≤0,05). Average value of TNF-α inabortion group was 3,83±1,52 ng/ml and normal pregnancy group with an average 2,76±1,49 ng/ml withp=0,032 (p≤0,05).Conclusion: In the abortion serum level of HLA-G is lower and TNF-α is higher than normal pregnancy.Keywords: Abortion, HLA-G, TNF-α.ABSTRAKLatar Belakang : Abortus merupakan salah satu penyebab morbiditas dan mortalitas maternal. Adanyapenolakan janin karena adanya antigen paternal oleh sistim imun ibu, diduga menjadi salah satu penyebabterjadinya abortus. Human Leukocyte Antigen G (HLA-G) yang dihasilkan oleh trofoblas dan Tumor NecrosisFactor Alpha (TNF-α) diduga sebagai salah satu mediator yang berhubungan dengan terjadinya abortus.Tujuan : Mengetahui kadar HLA-G dan TNF-α serum pada abortus dan kehamilan normalMetode: Penelitian ini merupakan penelitian observasional analitik menggunakan pendekatan CrossSectional yang dilakukan di RSUD Dr. Moewardi Surakarta pada bulan Agustus - November 2014. Totalsampel 40 dibagi menjadi 2 kelompok, 20 sampel kelompok abortus dan 20 sampel kelompok kehamilannormal. Semua sampel dilakukan pemeriksaan serum kadar HLA-G dan TNF-α dengan menggunakanmetode ELISA. Analisis menggunakan uji t dengan nilai kepercayaan 95%.Hasil dan Pembahasan: Rerata kadar serum HLA-G pada kelompok abortus adalah 55,0246±26,01 ng/ml dan kelompok kehamilan normal 76,7200±32,18 ng/ml, dengan nilai p=0,024 (p≤0,05). Rerata kadarserum TNF-α pada kelompok abortus 3,83±1,52 ng/ml dan kelompok kehamilan normal 2,76±1,49 ng/mldengan nilai p=0,032 (p≤0,05).Kesimpulan: Pada abortus kadar serum HLA-G lebih rendah dan TNF-α lebih tinggi bila dibandingkandengan kehamilan normal.Kata kunci : Abortus, HLA-G, TNF-α.1,2,3 Bagian Obstetri dan Ginekologi FK UNS/RSUD Dr. Moewardi Surakarta
The Effect of Prenatal Yoga on Anxiety and Depression in Kudus, Central Java Yulianti, Ika; Respati, Supriyadi Hari; Sudiyanto, Aris
Journal of Maternal and Child Health Vol 3, No 2 (2018)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

 Background: Anxiety and depression in pregnancy can lead to low fetal quality, increased risk of pregnancy complication and developmental disorder of the child. Antidepressant treatment may cause recurrence or addiction rate of up to 50%. In theory, yoga can relieve undesirable psychic symptoms such as anxiety and depression during pregnancy. This study aimed to determine the effect of prenatal yoga on anxiety and depression.Subjects and Method: This study was a randomized controlled trial, conducted at Budi Luhur clinic in Kudus, Central Java, from 27 December 2017 to 7 February 2018. A total of 102 pregnant women was selected for this study by simple random sampling. This sample was allocated at random into the intervention group (n1=51) and control group (n2=51). The independent variable was prenatal yoga as the intervention under study. The dependent variables were anxiety and depression. The data were collected by questionnaire. The difference in the dependent variables between the two groups was tested by Mann-Whitney test and multiple linear regression.Results: The mean level of anxiety was lower in the intervention group than the control group both at two weeks after the intervention (b= -9.25; 95% CI= -10.22 to -8.28; p< 0.001) and four weeks after the intervention (b= -5.79; 95% CI= -7.68 to -3.90; p< 0.001). The mean level of depression was lower in the intervention group than the control group both at two weeks after the intervention (b= -10.82; 95% CI= -12.29 to -9.35; p< 0.001) and four weeks after the intervention (b= -2.58; 95% CI= -3.98 to -1.18; p< 0.001).Conclusion: Prenatal yoga intervention can reduce anxiety and depression during pregnancy.Keywords: prenatal yoga, anxiety, depressionCorrespondence: Ika Yulianti. Masters Program in Public Health, Universitas Sebelas Maret, Jl. Ir. Sutami 36 A, Surakarta 57126, Central Java. Email: ikatamaevan@gmail.com. Mobile: +628115440036.Journal of Maternal and Child Health (2018), 3(2): 100-104https://doi.org/10.26911/thejmch.2018.03.02.02 
The Effect of Neoadjuvant Chemotherapy on HIF-1α Expression in Cervical Uterine Cancer Wiraswesty, Ika; Respati, Supriyadi Hari; Sulistyowati, Sri; Priyanto, Heru
Indonesian Journal of Medicine Vol 3, No 2 (2018)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Background: Uterine cervical cancer is one of the main causes of female death related to cancer. Neoadjuvant chemotherapy aims to reduce tumor mass to allow radical surgery. HIF-1α is thought to have a key role in the development of cancer and the main target for chemoprevention.Objective: This study aims to prove the effect of neoadjuvant chemotherapy on HIF-1α expression in uterine cervical cancer as an assessment parameter for chemotherapy response. Subjects and methods: The study was carried out in the Department of Obstetrics and Gynecology and the Pathology Department of Anatomy Dr. Moewardi - Faculty of Medicine, Sebelas Maret University, Surakarta. Thirty (30) cervical cancer samples that met the inclusion and exclusion criteria were examined for HIF-1α expression before and after giving 3 times neoadjuvant chemotherapy. Examination using immunohistochemical methods. Data analysis using t-test.Results: Mean HIF-1α expression before administration of neoadjuvant chemotherapy 5.10± 1.174 cell/field, after administration of neoadjuvant chemotherapy 4.00±1.174 cell/field with p=0.001.Conclusion: Neoadjuvant chemotherapy has an effect on reducing HIF-1α expression in uterine cervical cancer.Keywords: neoadjuvant chemotherapy, HIF-1α, uterine cervical cancerCorrespondence: Sri Sulistyowati. Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Sebelas Maret. Mobile: 08122968215. email: elis_spog@yahoo.co.id Indonesian Journal of Medicine (2018), 3(2): 119-124https://doi.org/10.26911/theijmed.2018.03.02.08
Vascular Endothelial Growth Factor-C Expression in Servical Squamous Cell Carcinoma of Patients with Neoadjuvant Chemotherapy Kartikasari, Uswatun Khasanah; Priyanto, Heru; Respati, Supriyadi Hari
Indonesian Journal of Medicine Vol 4, No 1 (2019)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Uterine cervical carcinoma is the most gynecological malignancy in women worldwide. The most common type of cervical carcinoma histology is squamous cell carcinoma and has a better prognosis than adenocarcinoma. Neoadjuvant chemotherapy is the management of early-stage cervical carcinoma before radical hysterectomy is performed. In addition to clinical-pathological factors, biomolecular markers are now being developed and used as parameters for evaluating chemotherapy responses. Vascular Endothelial Growth Factor-C is a VEGF derivative that plays a role in the process of vasculogenesis, limphangiogenesis, and the formation of new lymphatic channels which play an important role in metastasis. This study aimed to examine the effect of Paxus-Carboplatin chemotherapy in decreasing VEGF-C in squamous cell cervical carcinoma tissue.Subjects and Method: This was a quasi experiment study conducted at Department of Obstetrics and Gynecology and Pathology Anatomy Laboratory of Dr. Moewardi Hospital/ Faculty of Medicine, Universitas Sebelas Maret. 25 tissue samples of squamous cell stage IB2-IIA2 cervical carcinoma immunohistochemistry VEGF-C expression was carried out before and after Paxus-Carboplatin chemotherapy was given. The data were analyzed by Wilcoxon test.Results: VEGF-C expression in squamous cell cervical carcinoma tissue after chemotherapy was lower (mean = 4.20) than before chemotherapy (mean = 6.16) and it was statistically significant (p<0.001).Conclusion: Neoadjuvant chemotherapy decreases VEGF-C in squamous cell cervical carcinoma tissue.Correspondence: Uswatun Khasanah Kartikasari. Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Sebelas Maret/ Dr. Moewardi Hospital, Surakarta. Mobile: 081391444425. Email: uswatunkk@gmail.comIndonesian Journal of Medicine (2019), 4(1): 40-45https://doi.org/10.26911/theijmed.2019.04.01.07
Risk Factors of Maternal Death in Karanganyar, Central Java, Indonesia Kusnadi, Noferi; Respati, Supriyadi Hari; Sulistyowati, Sri
Journal of Maternal and Child Health Vol 4, No 6 (2019)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: The maternal mortality rate is an indicator of national health status. To reduce the Maternal Mortality Rate (MMR), especially in Karanganyar Regency, the risk factors that affect maternal mortality must be known.Subjects and Method:  This was a case-control study conducted in Karanganyar, Central Java, from 2016 to 2017. A sample of 57 study subjects was selected by fixed disease sampling. The dependent variable was maternal mor­tality. The independent variables were pregnancy complica­tions, labor complications, post­partum complications, maternal age, a distance of pregnancy, parity, maternal nutritional status during pregnancy, number of antenatal care visits, delay in making decisions, late referrals, late handling of staff, maternal education, maternal work, and income family. Data collected using questionnaires were then analyzed using bivariate analysis and multivariate analysis.Results: Maternal mortality was affected by pregnancy complications (OR= 6.98; 95% CI= 2.06 to 23.71; p= 0.001), labor complication (OR= 7.59; 95% CI= 2.19 to 26.28; p= 0.001), delayed labor (OR = 5.39; 95% CI= 1.17 to 24.75; p= 0.021), and family income (OR= 4.29; 95% CI= 1.28 to 14.41; p = 0.015).Conclusion: Maternal mortality was affected by pregnancy complications, labor complication, delayed labor, and family income.Keywords: risk factors, maternal mortality, Karanganyar RegencyCorrespondence: Noferi Kusnadi. Department of Obstetrics and Gynecology, Dr. Moewardi Hospital/ Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Central Java. Mobile: 08112654789. Email: noferikusnadi.og@gmail.comJournal of Maternal and Child Health (2019), 4(6): 499-506https://doi.org/10.26911/thejmch.2019.04.06.10 
FAKTOR ANGIOGENIK SOLUBLE FMS-LIKE TYROSINE KINASE-1 DAN VASCULAR ENDOTHELIAL GROWTH FACTOR PADA IBU HAMIL 8 – 20 MINGGU DENGAN RISIKO PREEKLAMPSIA Sulistyowati, Sri; Soetrisno, Soetrisno; Respati, Supriyadi Hari; Wiyono, Bambang Eko
JURNAL KESEHATAN REPRODUKSI Vol 2, No 1 (2015)
Publisher : Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan UGM

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Abstract

Sri Sulistyowati1, Soetrisno2, Supriyadi Hari Respati3, Bambang Eko Wiyono4 ABSTRACTBackground: Preeclampsia is still the main cause for maternal and neonatal mortality or morbidity. Anti-angiogenic Soluble FMS-Like Tyrosine Kinase-1 (sFlt-1) and proangiogenic Endhothelial Vascular Growth Factor (VEGF) factors can be used as an early detection of preeclampsia due to itsrole in the pathogenesis of preeclampsia, so it can be used as one effort to reduce maternal or perinatal morbidity and mortality.Objective: To analyze sFlt-1 and VEGF levels in the serum of normal pregnancy and pregnancy with preeclampsia risk in 8 – 20 weeks gestation.Method: Observational analytic with cross sectional method performed at the Obstetrics and Gynecology, Dr. Moewardi Hospital/ Medical Faculty Sebelas Maret University Surakarta and Prodia laboratory since November – December 2013. Number of samples studied was 30 samples, comprising 15 samples of normal pregnancy and pregnancy with preeclampsia risk with 8 – 20 weeks of gestational age. The sFlt-1 and VEGF serum levels was assessed using ELISA and analyzed using t-test.Result & Discussion: Serum level of sFlt-1 in normal pregnancy is (1252,17±564,65 ng/ml), and in pregnancy with preeclampsia risk is (1741,90±640,97 ng/ml) with p=0,023 serum level of VEGF in normal pregnancy was 96,88±144,29 ng/ml and in pregnancy with preeclampsia risk was 14,24±8,73 ng/ ml with p=0,044.Conclusion: sFlt-1 level is higher and VEGF level is lower in pregnant women with preeclampsia risk than normal pregnancy on 8 – 20 weeks gestational age.Keywords: Pregnancy, Preeclampsia Risk, sFlt-1, VEGF.ABSTRAKLatar belakang: Preeklampsia saat ini masih merupakan masalah pada ibu hamil yang berhubungan dengan mortalitas dan morbiditas maternal dan perinatal. Faktor anti-angiogenik Soluble FMS-Like Tyrosine Kinase-1 (sFLt-1) dan proangiogenik Vascular Endhothelial Growth Factor (VEGF) diduga dapat digunakan sebagai deteksi dini karena perannya dalam patogenesis preeklampsia, sehingga dapat digunakan sebagai upaya untuk mengurangi angka morbiditas dan mortalitas maternal dan perinatal. Tujuan: Untuk menganalisis kadar sFlt-1 dan VEGF pada serum ibu hamil normal dan ibu hamil dengan risiko preeklampsia pada usia kehamilan 8 – 20 minggu.Metode: Penelitian observasional analitik dengan metode Cross Sectional yang dilakukan di bagian Obstetri dan Ginekologi, RSUD Dr. Moewardi/ FK UNS, Surakarta dan Laboratorium Prodia mulai Nopember – Desember 2013. Jumlah sampel terdiri 30 yang terbagi menjadi 15 sampel ibu hamil normal dan dan 15 sampel ibu hamil dengan risiko preeklampsia usia gestasi 8 – 20 minggu. Masing-masing dianalisis kadar sFlt-1 dan VEGF pada serumnya dengan metode ELISA dan dianalisis menggunakan uji t.Hasil & Pembahaasan: Kadar serum sFlt-1 pada kehamilan normal (1252,17±564,65 ng/ml), kehamilan dengan risiko preeklampsia (1741,90±640,97 ng/ml) dengan nilai p=0,023 dan kadar VEGF pada kehamilan normal (96,88±144,29 ng/ml), kehamilan dengan risiko preeklampsia (14,24±8,73 ng/ ml) dengan nilai p=0,044.Kesimpulan: Kadar sFlt-1 lebih tinggi dan kadar VEGF lebih rendah pada kehamilan dengan risiko preeklampsia dibanding kehamilan normal pada usia hamil 8 – 20 minggu.Kata kunci: Kehamilan, Risiko Preeklampsia, sFlt-1, VEGF.1,2,3,4Sri Sulistyowati, Bagian Obgin FK UNS/ RSUD Dr. Moewardi, Jl. Kol. Sutarto 132 Surakarta. Telp. 08122968215, Email: elis_spog@yahoo.co.id
Analisis Faktor Determinan Kematian Ibu di Kabupaten Sukoharjo Jawa Tengah Indonesia Respati, Supriyadi Hari; Sulistyowati, Sri; Nababan, Ronald
JURNAL KESEHATAN REPRODUKSI Vol 6, No 2 (2019)
Publisher : Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (301.084 KB) | DOI: 10.22146/jkr.43463

Abstract

LatarBelakang: Kematian ibu di kabupaten Sukoharjo masih cukup tinggi. Hal ini disebabkan oleh beberapa faktor seperti 4 “terlalu” ,komplikasi kehamilan, persalinan dan nifas,terlambat mengambil keputusan, merujuk dan mendapat pelayanan kesehatanserta sosioal ekonomi yang rendah.Metode: Observasional analitik dengan case control study. Jumlah sampel 16 kasus dan 32 kontrol dengan teknik simple random sampling. Analisis dilakukan secara univariat, bivariat dengan chi square test, multivariat dengan metode regresi logistik.Hasil: Terdapat hubungan yang bermakna antara komplikasi kehamilan (p<0.034) (OR=4,200; 95% CI : 1,064 – 16,584), komplikasi persalinan (p<0.001) (OR=9,533; 95% CI : 2,397 – 37,909), komplikasi nifas (p<0.000), keterlambatan penanganan petugas (p=0,011),paritas (OR=0,035; 95% CI : 0,004 – 0,300; p=0,000) dan ibu bekerja (p=0,017)(OR=4.592; 95% CI : 1.257 – 16.771) terhadap kematian maternal. Dengan faktor  risiko di atas kemungkinan kematian maternal meningkat sebanayak 88,9 %.Kesimpulan: Komplikasi kehamilan, persalinan, nifas ,keterlambatan penanganan petugas, paritas dan ibu bekerja meningkatkan risiko kematian maternal
Peran Magnesium Sulfat dalam Menurunkan Kadar TNF-α dan IL-1β pada Bayi Prematur Sulistyowati, Sri; Pujojati, Ferri Waluyo Wiwoho; Respati, Supriyadi Hari; -, Soetrisno -
Jurnal Kedokteran Brawijaya Vol 29, No. 4 (2017)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (199.893 KB) | DOI: 10.21776/ub.jkb.2017.029.04.7

Abstract

Prematuritas menyebabkan mortalitas dan morbiditas neonatus yaitu cerebral palsy (CP), gangguan kognitif dan gangguan tingkah laku. Sitokin proinflamasi TNF-α dan IL-1β diduga secara signifikan meningkat pada bayi prematur. Magnesium sulfat (MgSO4) diduga dapat sebagai neuroprotektor terhadap otak janin, melindungi jaringan terhadap aktivitas radikal bebas, sebagai vasodilator dari vasculature otak dan menurunkan sitokin proinflamasi. Penelitian ini bertujuan untuk mengetahui peran MgSO4 terhadap kadar TNF-α dan IL-1β pada bayi prematur, menggunakan metode observasional analitik, cross sectional yang dilakukan pada bulan Januari-Desember 2015 di RSUD Dr. Moewardi Surakarta dan laboratorium Prodia Jakarta. Subjek penelitian berjumlah 40 yang memenuhi kriteria inklusi dan eksklusi dibagi menjadi 2 kelompok yaitu 20 subjek kelompok persalinan prematur yang mendapat MgSO4 dan 20 subjek kelompok persalinan prematur tidak mendapat MgSO4. Semua subjek dilakukan pemeriksaan kadar TNF-α dan IL-1β pada serum dari darah tali pusat bayi pada saat lahir dengan menggunakan metode ELISA. Data dianalisis menggunakan uji t. Rerata kadar serum TNF-α pada kelompok persalinan prematur yang diberikan MgSO4 (2,24±0,56ng/mL) dan rerata kadar serum TNF-α pada persalinan prematur yang tidak diberikan MgSO4 (2,80±0,85ng/mL) dengan p=0,01 (p&lt;0,05). Rerata kadar serum IL-1β pada kelompok persalinan prematur yang diberikan MgSO4 (0,49±0,22ng/mL) dan rerata kadar serum IL-1β pada persalinan prematur yang tidak diberikan MgSO4 (0,71±0,28ng/mL) dengan p=0,01 (p&lt;0,05). Magnesium Sulfat berperan menurunkan kadar serum TNF-α dan IL-1β pada bayi prematur.
THEORY OF PLANNED BEHAVIOR AND HEALTH BELIEF MODEL ON FACTORS ASSOCIATED WITH BREAST SELF EXAMINATION AMONG UNIVERSITY STUDENTS Fajriah, Asruria Sani; Respati, Supriyadi Hari; Murti, Bhisma
Journal of Health Promotion and Behavior Vol 4, No 4 (2019)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: The new cases of breast cancer worldwide are estimated at 1,384,155 with almost 459,000 related deaths. A common problem for breast cancer treatment is patients who often come to a health care provider when they are in the final stages of cancer. Early detection of breast cancer can be conducted by using the method of Breast Self Examination (BSE). This study aimed to analyze the determinant of Breast Self Examination (BSE) in female university students.Subjects and Method: This study used a cross sectional design. This study was conducted at Universitas Sebelas Maret, Surakarta, Central Java, from August-September 2019. A sample of 200 female university students was selected by simple random sampling. The dependent variable was Breast Self Examination. The independent variables were age, perceived barrier, self-efficacy, subjective norm, and attitude. The data were collected by using questionnaires. The data were analyzed by a multiple logistic regression run on Stata 13.Results: Breast Self Examination (BSE) increased with age ?20 years (OR=5.01; 95%CI=1.79 to 14.00; p=0.002), positive perceived barrier (OR=0.0CI8;95%=0.03 to 0.27; p<0.001), strong self-efficacy (OR=6.40; CI 95%=2.53  to 16.23; p<0.001), strong subjective norm (OR=4.13; 95%CI= 1.55 to 10.99; p=0.004), and positive attitude (OR=7.55; 95%CI= 2.57 to 22.22; p=0.022).Conclusion: Breast Self Examination (BSE) increased with age, perceived barrier, self-efficacy, subjective norm, and attitude.Keywords: breast cancer, breast self examination, theory of planned behavior, screeningCorrespondence: Asruria Sani Fajriah. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: sanifajriah­@­gmail.com. Mobile: +6285790341801.Journal of Health Promotion and Behavior (2019), 4(4): 246-257https://doi.org/10.26911/thejhpb.2019.04.04.01
Co-Authors -, Soetrisno - Adhi, Kresno Condro Adiyana, Febrian Andhika Alamsyah, Meuthia Ambar Mudigdo Antonius Budi Giri Bawono, Antonius Budi Giri Argyo Demartoto, Argyo Aris Sudiyanto Aristin, Okid Parama Arwiyantasari, Wida Rahma Astetri, Lini Bachnas, Muhammad Adrianes Bambang Eko Wiyono, Bambang Eko Bhisma Murti Carissa, Dinda Diffah Hanim Ediningtyas, Atifa Nadira Elita Rahmi Eriana Melinawati Eric Edwin Yuliantara Eti Poncorini Pamungkasari Fajriah, Asruria Sani Fitriawan, Ahmad Hermawan Udiyanto Heru Priyanto John Arianto Sondakh, John Arianto Kartikasari, Uswatun Khasanah Karuniawati, Benny Khoeronisa, Siti Kurniawan, Hendro Kusnadi, Noferi Laqif, Abdurahman Mahandaru, Araafi Hariza Miftahus Saadah, Miftahus Mubarokah, Rizka Innayatun Muhammad Adrianes Bachnas MUHAMMAD AGUS SUPRAYUDI Nababan, Ronald Nasrudin, Muhamad Nurinasari, Hafi Nurul Husna Nutria Widya Purna Anggraini Nuur, Aliffudin Okid Parama Astirin Pella Todungbua', Prima Derry Pradana, Muhammad Denny Gagah Prasetya, Hanung Pujojati, Ferri Waluyo Wiwoho Rahmawati, Deni Nur Fauzia Rahmawati, Oktantia Dyah Rasyiid, Astika Ratna Diana Fransiska Ratnasari Dwi Cahyanti, Ratnasari Dwi Ratnasari, Affi Angelia Ridwan, Robert Rizkiani, Inne RUBEN DHARMAWAN Saputra, Ricky Bernadi Sesunan, Arfan Syahfani SITI MARYANI Soetrisno Kasan Wiharjo, Soetrisno Kasan Soetrisno Soetrisno Sri Mulyani Sri Sulistyowati Sulistywati, Sri Uki Retno Budihastuti Ulfah, Maharani Wiraswesty, Ika WISNU PRABOWO Yeni Andriani, Yeni Yuliani, Saffana Oka