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All Journal JURNAL GIZI INDONESIA Nurse Media Journal of Nursing UG Journal Journal of Nutrition College Forum Agribisnis Journal of Consumer Science Mutiara Medika: Jurnal Kedokteran dan Kesehatan The Indonesian Biomedical Journal ELT Forum: Journal of English Language Teaching Journal of Consumer Sciences Jurnal Ilmu Keluarga dan Konsumen Journal of Innovative Science Education Medica Hospitalia Jurnal Health Sains Diponegoro International Medical Journal (DIMJ) Jurnal Keperawatan Klinis dan Komunitas (Clinical and Community Nursing Journal) Neurona Seroja Husada: Jurnal Kesehatan Masyarakat Jurnal Info Kesehatan Eko-Regional: Jurnal Pembangunan Ekonomi Wilayah Eko-Regional: Jurnal Pembangunan Ekonomi Wilayah
Retnaningsih Retnaningsih
Departemen Ilmu Keluarga dan Konsumen Fakultas Ekologi Manusia Institut Pertanian Bogor
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Journal : Neurona

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Luaran Klinis dan Komplikasi Terapi Endovaskular pada Pasien Stroke Iskemik Akut dengan Trombolisis Intra-Arteri dan Trombektomi Mekanik pada Setting Penanganan Kritis Retnaningsih, Retnaningsih; Tugasworo, Dodik; Kurnianto, Aditya; Tri Rahayu, Fitriani
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 41 No 3 (2025): Vol 41 No 3 (2024): Volume 41, No 3 - Juni 2025
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v41i3.774

Abstract

Introduction: Acute ischemic stroke (AIS) is a major cause of disability and death worldwide. Mechanical thrombectomy (MT) has become the standard endovascular therapy for AIS with large vessel occlusion, though incomplete reperfusion remains a concern. Intra-arterial thrombolysis (IA-T) has emerged as a potential adjunct therapy to enhance reperfusion. Aim: To evaluate clinical outcomes and complication rates between IA-T plus MT compared to MT alone in AIS patients treated in the ICU of Dr. Kariadi Hospital, Semarang. Methods: A total of 38 AIS patients with MCA occlusion who received endovascular reperfusion therapy were divided into two intervention groups: IA-T + TM (n=18) and TM alone (n=20). Outcomes according to Modified Rankin Scale (mRS) score and complication data were compared between groups. Results: Patients in both groups had similar baseline characteristics. A higher percentage of patients in the IA-T + MT group achieved favorable mRS scores (0–2) compared to the MT-only group (72.2% vs 65%), though the difference was not statistically significant (p=0.632). No significant differences in complication rates were found. Discussion: The combination of IA-T and MT showed a trend toward better functional outcomes without significantly increasing complications. This suggests potential benefit in selected cases. Keywords: ischemic stroke, intra-arterial thrombolysis, mechanical thrombectomy
Co-Authors Afina, Siti Agung, Locoporta Aisy, Rihadatul Al Mutanafisa, Tasneem Alfiasari Amalia Khairati Amin Husni Andhitara, Yovita Andhitara, Yovita Andhitara Ani Ruwani, Ani Anita Saufika Anjani, Gemala Ardhini, Rahmi Arifin Triyanto Arina Hayati Asep Taryana Budisulistyo, Trianggoro Caroline, Maria Daynuri, Daynuri Daynuri, Riri Diah Retno Wahyuningrum Dini Aprilia Dodik Tugasworo Drajat Martianto Dwi Febryanto Endang Gumbira Sa’id Endang Kustiowati Erni Hernawati Purwaningsih, Erni Hernawati Fadila Ramadini Febriantina Dewi Fibria Mustikarini, Fibria Firina Firina Firli Bramantyo, Dion Fitri Octaviana Fitria Handayani Hajijah, Rengganis Novyanti Hamdani, Faishol Handaru Tri Mulyono Hanisa Rahmina Fitriyana Hartono, Jimmy Eko Budi Hartoyo Hartoyo Irni Rahmayani Johan Istiqlaliyah Muflikhati Jaeri, Santoso Jethro Budiman, Jethro Junedi, Rahmat Juswanto, Gerard Kurnianto, Aditya Kurnianto, Aditya Kurnianto Lia Yuliana Lilik Noor Yuliati Martha Irene Kartasurya Megawati Simanjuntak Nana Rochana, Nana Nani Maharani Noni Widiawatie Nuraini Nuraini Pasmanasari, Elta Diah Priambada, Dody Purba, Jan Sudir Puspitawati, Arinta Putri, Ayulia Karisma Putri, Marietta Krisnaya Nandika Putri, Nadya Yona Eka Rahmawati, Dani Rahmayanti Rahmayanti Rahmi Parhati RIA ANGGRAINI Saiful Ridlo Satrioaji, Hari Wahono Sofro, Muchlis AU Achsan Udji Sri Anna Marliyati Suryadi Suryadi Suryawati, Herlina Syahrul Syahrul Tamad, Fatiha Sri Utami Tri Rahayu, Fitriani Tri Subekti Trisnaningtyas, Wenny Tsaniadi Prihastomo, Krisna Tugasworo, Dodik ` Ujang Sumarwan W.H, Nugrahaningsih Wahyuni, Ribut Nurul Tri Widaryanti, Widya Bella Yudiatma, Muh. Firman Yuridis, Melani Sukma