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Journal : Radioterapi

Cancer Profile in East Jakarta: A 5-year descriptive study Gondhowiardjo, Soehartati Argadikoesoema; Hanum, Fathiya Juwita; Hanifah, Rizka; Priharto, R Koesmedi; Yekti, Widyastuti Endro
Radioterapi & Onkologi Indonesia Vol 9, No 2 (2018): Volume 9 No.2 Juli 2018
Publisher : Perhimpunan Dokter Spesialis Onkologi Radiasi Indonesia (PORI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (781.977 KB) | DOI: 10.32532/jori.v9i2.87

Abstract

Background: Global Burden of Cancer (GLOBOCAN) 2012 estimated there were 8.2 million cancer deaths worldwide, 65% of them were in developing countries. In Indonesia, the cancer incidence is 134 per 100,000 population. The magnitude of the burden caused by cancer requires a valid data collection in each country in an effort to plan and evaluate cancer prevention programs in the future. Based on Indonesian Minister of health decree, Dr. Cipto Mangunkusumo Hospital (RSCM) was determined as Cancer Registry Control Center in DKI Jakarta Province. This study aims to report Cancer Profile in East Jakarta 2008-2012 based on RSCM Data.Methods: This research was a cross-sectional descriptive study. Patient data were extracted from DKI Jakarta Cancer Registry Control Center Located at RSCM. The primary site and histology of malignancies were identified and coded based on the International Classification of Diseases for Oncology.Results: There were 3748 cancer patients who live in East Jakarta, with male and female ratio of 1:1.9. Most of them were between 45-54 years old. The majority of patients came to health providers with advanced stage (stage 3 and 4). At both sexes the most frequent cancer were breast cancer, followed by cervical cancer, hematopoietic and reticuloendothelial system malignancy, nasopharyngeal cancer, and lung and bronchial cancer. The five most common cancers in men were nasopharyngeal cancer, hematopoietic and reticuloendothelial system malignancy, lung and bronchial cancer, liver and intrahepatic bile duct cancer, and lymph node cancer, respectively. While in women, the five most common cancers were breast cancer, cervical cancer, ovarian cancer, hematopoietic and reticuloendothelial system malignancy and thyroid gland cancer, respectively.Conclusion: Most of cancer patients are in productive age and the majority of them came at advanced stage. Furthermore, three of five most common cancer charge both genders (hematopoietic and reticuloendothelial system malignancy, nasopharyngeal cancer, and lung and bronchial cancer).
Cancer Profile in East Jakarta: A 5-year descriptive study Soehartati Argadikoesoema Gondhowiardjo; Fathiya Juwita Hanum; Rizka Hanifah; Sri Mutya Sekarutami; Nadia Christina; Steven Octavianus; R. Koesmedi Priharto; - Widyastuti
Radioterapi & Onkologi Indonesia Vol 9, No 2 (2018): VOLUME 9 NO. 2 JULI 2018
Publisher : Perhimpunan Dokter Spesialis Onkologi Radiasi Indonesia (PORI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (780.956 KB) | DOI: 10.32532/jori.v9i2.91

Abstract

Background: Global Burden of Cancer (GLOBOCAN) 2012 estimated there were 8.2 million cancer deaths worldwide, 65% of them were in developing countries. In Indonesia, the cancer incidence is 134 per 100,000 population. The magnitude of the burden caused by cancer requires a valid data collection in each country in an effort to plan and evaluate cancer prevention programs in the future. Based on Indonesian Minister of health decree, Dr. Cipto Mangunkusumo Hospital (RSCM) was determined as Cancer Registry Control Center in DKI Jakarta Province. This study aims to report Cancer Profile in East Jakarta 2008-2012 based on RSCM Data.Methods: This research was a cross-sectional descriptive study. Patient data were extracted from DKI Jakarta Cancer Registry Control Center Located at RSCM. The primary site and histology of malignancies were identified and coded based on the International Classification of Diseases for Oncology.Results: There were 3748 cancer patients who live in East Jakarta, with male and female ratio of 1:1.9. Most of them were between 45-54 years old. The majority of patients came to health providers with advanced stage (stage 3 and 4). At both sexes the most frequent cancer were breast cancer, followed by cervical cancer, hematopoietic and reticuloendothelial system malignancy, nasopharyngeal cancer, and lung and bronchial cancer. The five most common cancers in men were nasopharyngeal cancer, hematopoietic and reticuloendothelial system malignancy, lung and bronchial cancer, liver and intrahepatic bile duct cancer, and lymph node cancer, respectively. While in women, the five most common cancers were breast cancer, cervical cancer, ovarian cancer, hematopoietic and reticuloendothelial system malignancy and thyroid gland cancer, respectively.Conclusion: Most of cancer patients are in productive age and the majority of them came at advanced stage. Furthermore, three of five most common cancer charge both genders (hematopoietic and reticuloendothelial system malignancy, nasopharyngeal cancer, and lung and bronchial cancer). 
Peran Radioterapi pada Melanoma Kulit Fathiya Juwita Hanum; Nana Supriana
Radioterapi & Onkologi Indonesia Vol 10, No 1 (2019): VOLUME 10 NO.1 JANUARI 2019
Publisher : Perhimpunan Dokter Spesialis Onkologi Radiasi Indonesia (PORI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (561.606 KB) | DOI: 10.32532/jori.v10i1.96

Abstract

Melanoma maligna merupakan keganasan sel penghasil pigmen (melanosit) yang terutama terdapat pada kulit, namun dapat juga ditemukan pada mata, telinga, mulut, saluran cerna, mukosa genital dan leptomeningen. Melanoma adalah kanker kulit yang bersifat sangat agresif dengan peningkatan insiden pada beberapa dekade terakhir.Pembedahan merupakan modalitas utama dan paling efektif pada kasus melanoma. Namun, pada kondisi dimana pembedahan tidak dapat dilakukan secara radikal atau terdapat faktor prognostik yang buruk dari hasil histopatologi pasca operasi, maka diperlukan terapi adjuvan sebagai tambahan. Dalam kaitannya dengan hal tersebut, radioterapi memiliki peran yang efektif. Lebih lanjut, indikasi radiasi, dosis dan fraksinasi serta target volume akan dipaparkan pada tinjauan ini. 
Secondary Malignancy pasca Radioterapi Fathiya Juwita Hanum; Sri Mutya Sekarutami
Radioterapi & Onkologi Indonesia Vol 7, No 2 (2016): Volume 7 No.2 Juli 2016
Publisher : Perhimpunan Dokter Spesialis Onkologi Radiasi Indonesia (PORI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (841.991 KB) | DOI: 10.32532/jori.v7i2.48

Abstract

Perkembangan teknologi kedokteran dibidang Radioterapi dalam pengobatan kanker telah berdampak terhadap angka harapan hidup pasien kanker yang menjadi lebih tinggi. Hal ini juga diiringi dengan meningkatnya risiko terjadinya secondary malignancy pasca radiasi. Efek bystander radiasi menyebabkan sel yang tidak menjadi target radiasi, tapi posisinya berdekatan dengan sel target pada saat terjadinya paparan radiasi juga terkena dampak radiasi secara biologis. Berbagai strategi telah dikembangkan untuk memperbaiki rasio terapeutik pada banyak kasus keganasan yang diterapi dengan radiasi. Hal ini diharapkan dapat meningkatkan kemungkinan kontrol lokal pada tumor sekaligus mengurangi efek samping terhadap jaringan sehat disekitarnya yang tidak menjadi target radiasi.