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Angga Saputra
Program Studi Pendidikan Jasmani dan Rekreasi FKIP Untan, Pontianak
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Journal : Science and Technology Indonesia

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Synthesis of a 3D Porous Multicomponent Bioceramic Scaffold Sari, Yessie Widya; Munir, Ryaas Mishbachul; Saputra, Angga; Sari, Mona; Aminatun; Suciati, Tri; Mohamad, Che Wan Sharifah Robiah; Gunawarman; Yusuf, Yusril
Science and Technology Indonesia Vol. 9 No. 2 (2024): April
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2024.9.2.235-243

Abstract

In this study, 3D porous multicomponent bioceramic scaffolds were fabricated. Hydroxyapatite (HA) and carbonate-substituted hydroxyapatite (CHA) synthesized from Asian moon scallop shell (Amusium pleuronectes) served as the bioceramics, whereas alginate and chitosan served as the polymeric components. The study was focused on determining whether the presence of polyvinyl alcohol (PVA) in the scaffold exerted an impact. When PVA was not included, the morphological examination revealed that the samples exhibited porous structures characterized by effective pore interconnectivity and a substantial pore size. X-ray diffraction and scanning electron microscopic analyses indicated that the inclusion of PVA led to a decrease in the crystallinity, pore size, and porosity of the scaffolds. Those containing PVA exhibited porosity levels in the range of 56%–60%, and pore sizes ranged from 42 to 90 µm. These properties may provide advantages for the scaffold with respect to the ability for cell migration and cell attachment, thus enhancing new bone formation. Moreover, the compositions of HA and chemically modified HA (CHA) within the scaffold influenced the crystallinity and uniformity of the scaffold morphology. This finding suggests the potential for crafting a customized porous bioceramic scaffold based on specific compositions.
Co-Authors A.A. Ketut Agung Cahyawan W Abubakar, Rafeah Abubakar, Rafeah Aimmah, Aisy Wildatil Albino, Kevin Aminatun Amiruddin Amiruddin Ardha, Dea Justicia Badrotinnajah, Arju Batubara, Mustopa Marli Darmadi, Djarot Bangun Darmawati Darmawati Dewi, Linda Atika Diana, Raden Rachmy Dwi sona EKO HARYADI Euis Ismayati Fadhly, Ahmad Fatiyah, Salsabila Febriyani, Evy Fibrianto, Sutrisno Grace, Patricia Gunawarman Habib Ismail, Habib Haniza, Sjelly Hariyadi, Wicaksono Putra Haryadi, Wicaksono Putra Herdyan, Rafi Dhianaufal Herman Bedi Agtriadi, Herman Bedi Islamiyah, Anisatin Julianda, Pito Jusi, Ulfa Karima, Annur KOMALASARI, YULI La Goa, Yusnita Lestari, Sri Maria Puji Liyantono . luqman M. Yusuf Arifin, M. Yusuf Maemonah, Maemonah Meini Sondang Sumbawati Miranti Miranti Mohamad, Che Wan Sharifah Robiah Mualip, Mualip Muarofah Ghofur, Muarofah Muhammad Taufiq Munir, Ryaas Mishbachul Nur’ainy, Nur’ainy Oki Darmawan Prasetyo, Dian Estu Pristianto, Hendrik Rakhmat, Rakhmat Rakhmayanti, Dyah Ricky, Zuhar Rifki, Muhamad Fahri Nur Rita Rahmawati Rito Cipta sigitta Hariyono Rohmat, Xepy Abdul Rudi Salam Sinaga Salfa, Refanti Samsuniyah, Samsuniyah Sandayanti, Vira Santoso, Haris Saputra, Muhamad Adi Saraswati, Nurul Mega Sari, Mona Sari, Nelfa Silmiati, Silmiati Supratama, Riky Suyadi Suyadi Syafrowi, M. Mualla Syahril, Ahmad Syukira, Nikma Syukira Talice, Marco Tri Suciati Utami, Deviani Utomo, Sabrina Salsabila Utomo, Slamet Prasetyo Victor Simanjuntak Vitamia, Cszahreyloren Yasintha Sari Pratiwi YB Andre Marvianta Yessie Widya Sari Yusril Yusuf Zaili Rusli