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The Application of The Polya's Steps Reviewed from Problem-Solving Ability in Two-Variable Linear Equation System (SPLDV) Sepriyanti, Nana; Trinova, Zulvia; Susanto, Andi
Tarbiyah : Jurnal Ilmiah Kependidikan Vol. 9 No. 1 (2020): June
Publisher : Universitas Islam Negeri Antasari Banjarmasin, South Kalimantan, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18592/tarbiyah.v9i1.3543

Abstract

The ability of students in this school is low in understanding the questions given by the teacher. As a result they find it difficult to know the steps on how to solve the problem. Efforts that can be done are implementing Polya's steps.Quasi-experimental research was conducted in this study with the Randomized Control Group Only Design. Students of class VIII at this school are used as population. The experimental class is class VIIIA and the control class is class VIIIB. Final test data in the form of essays obtained were analyzed by t test. The result is the average problem solving ability with the application of Polya's steps, 78.23 and the control class, 72.38, with achievement in the experimental class 81% and in the control class, 48%. After being analyzed, t_count = 2.33 and t_table = 1.68 with a confidence level of 95% so that t_count > t_table (2.33 > 1.68), meaning that the proposed hypothesis is accepted and the ability of students in solving problems using Polya steps is higher rather than without applying these steps.
Tinjauan Hukum Islam Dan Hukum Positif Terhadap Pembelian Mystery Box di E-Commerce (Shopee) Susanto, Andi; Muslimah, Nur
AQaduna : Jurnal Hukum Ekonomi Syariah Vol 2 No 1 Februari 2024
Publisher : Sekolah Tinggi Agama Islam Nurul Huda Kapongan Situbondo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52491/aqaduna.v2i1.134

Abstract

Mystery box adalah salah satu promosi dalam penjualan dengan menjual kotak dimana produk yang terdapat didalamnya tidak pasti dan bisa mencakup berbagai barang, sehingga pembeli tidak dapat menebak apa yang ada di dalamnya atau apa yang akan mereka dapatkan nanti. Metode promosi penjualan mystery box kini ada di semua toko online e-commerce saat ini. tujuan penelitian ini menjelaskan mengenai pengertian dan hukum secara syariat islam dan hukum positif di indonesia. dan dapat disimpulkan bahwa dalam promosi penjualan mystery box Meskipun produk tersebut dimiliki oleh penjual dan memiliki keuntungan, perjanjian sesuai dengan syariat, serta ijab dan qabul dinyatakan sah meskipun kedua belah pihak tidak berada di tempat yang sama. Namun, menurut hukum islam jual beli dengan sistem kotak misteri tidak sah karena salah satu pihak tidak mengetahui isi produk yang akan diterimanya yakni mengandung ketidakjelasan (gharar). Karena tidak terpenuhinya syarat sah jual beli yang tercantum dalam pasal 1320 KUHPerdata, yaitu syarat objek, maka Jual beli misteri kotak juga tidak diperbolehkan menurut hukum positif.
Analisis Karakter Klinikopatologik pada Kasus Karsinoma Payudara Subtipe Luminal A Like Susanto, Andi; Dewayani,, Birgitta Maria; Hernowo, Bethy Surjawathy
Majalah Patologi Indonesia Vol. 30 No. 3, September 2021
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55816/mpi.v30i3.477

Abstract

BackgroundMolecular subtypes of breast carcinoma, luminal A like has the best prognosis, but in the previous studies there were cases thatshowed poor clinical outcomes. This study attempted to investigate the clinicopathological characteristics in luminal A like subtypebreast carcinoma.MethodsThis study is a cross sectional study. The samples used were 67 medical records of patients with luminal A like subtype breastcarcinoma in January 2014 to June 2019 period from Hasan Sadikin Hospital, Bandung. According to estrogen receptor (ER) andprogesteron receptor (PR) expression status by adding both intensity and distribution scores, the data were divided into twosubgroups: low histoscore (<7) and high histoscore (≥7). Clinicopathological characteristics (age, TNM stage, treatment, location,histologic type, grading and metastasis) were evaluated for each subgroup.ResultsFrom 67 luminal A like subtype breast carcinoma patients, 73.13% were in the high histoscore subgroup, with higher percentage oflow grade histopathologic features (63.27%). There were no significant differences in age and TNM staging between the twosubgroups. Among 67 breast carcinoma patients, 43 were diagnosed in advanced stages. There were significant differences inlymph nodes metastasis between the two subgroups (p-value 0.013), however, there were no significant difference in metastasis toother organs.ConclusionThis study shows that 73.13% of patients with luminal A like subtype breast carcinoma have a high histoscore of hormone receptor.Low histoscore subgroups luminal A like subtype breast carcinoma will metastasize to lymph nodes.
ANALYSIS OF THE EFFECTIVENESS OF DUAL PI3K/mTOR INHIBITORS IN INHIBITION OF PI3K/AKT/mTOR SIGNALING PATHWAY IN BREAST CANCER Susanto, Andi; Subardin, Dian Aryanti; Gunadi, Julia Windi; Sanjaya, Ardo
Medika Kartika : Jurnal Kedokteran dan Kesehatan Vol 8 No 4 (2025): Medika Kartika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran Universitas Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Breast cancer is a malignancy originating from breast cells, ducts, and tissues that can occur due to genetic mutations due to DNA damage in normal cells. The PI3K/Akt/mTOR pathway is an intracellular pathway that plays an important role in regulating basic cell functions such as cell growth, movement, survival, metabolism, and angiogenesis. Some examples of PI3K/mTOR pathway inhibitor drugs on the market and often used are dactolisib, samotolisib, voxtalisib, and so on. These drugs are more effective than single-pathway inhibitors. This article was prepared using the literature review method. The data used in this article were obtained from the PubMed and Google Scholar using the keywords breast cancer, PI3K/Akt/mTOR inhibitor, and PI3K/AKT/mTOR signaling pathway. Several studies suggest that the PI3K-AKT-mTOR pathway is critical in mediating the proliferation and migration of breast cancer cells. Because of the importance of the PI3K-AKT-mTOR pathway in the pathogenesis of breast cancer, it is often used as a target for breast cancer therapy. PI3K/mTOR dual ATP competitive inhibitors can directly act on the main target proteins of PI3K and mTOR, thereby more efficiently inhibiting the PI3K/AKT/mTOR signaling pathway and effectively preventing other factors that can activate the PI3K pathway, and reducing the resistance and side effects produced by single inhibitors. Keywords: breast cancer, dual inhibitor, PI3K-AKT-mTOR DOI : 10.35990/mk.v8n4.p434-445
SEJARAH STUDI ISLAM KLASIK MODERN KONTEMPORER: TOKOH & ALIRAN Anwar, Kasful; Saidek , Abdul Rahim; Afriyanti, Rita; Fermidera, Icha; Susanto, Andi
Pendas : Jurnal Ilmiah Pendidikan Dasar Vol. 11 No. 01 (2026): Volume 11 No. 01, Maret 2026 Release
Publisher : Program Studi Pendidikan Guru Sekolah Dasar FKIP Universitas Pasundan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23969/jp.v11i01.42406

Abstract

This article examines the historical development of Islamic Studies from the classical, modern, to contemporary periods, with a particular focus on the figures and intellectual trends that have shaped the discipline over time. Islamic Studies did not emerge as a static field of knowledge, but rather evolved dynamically in response to social, political, cultural, and intellectual changes within the Muslim world. During the classical period, Islamic Studies were characterized by the formation of core Islamic disciplines such as Qur’anic exegesis, Hadith studies, jurisprudence, and theology, developed through normative and theological approaches by classical Muslim scholars. In the modern period, Islamic Studies experienced significant paradigm shifts as responses to colonialism, modernization, and Western intellectual challenges, giving rise to reformist thinkers who emphasized rational, historical, and contextual approaches. In the contemporary period, Islamic Studies have increasingly adopted multidisciplinary perspectives, incorporating methods from the social sciences and humanities while engaging with global issues such as pluralism, gender, human rights, and democracy. This study employs a library research method using a historical-analytical approach to examine major works and ideas of prominent scholars in Islamic Studies. The findings indicate that the development of Islamic Studies reflects a continuous intellectual effort to interpret and contextualize Islamic teachings in accordance with changing historical realities. This article is expected to contribute to the academic discourse by providing a comprehensive overview of the intellectual map and future direction of Islamic Studies.