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All Journal Kertha Negara : Journal Ilmu Hukum Jurnal NERS Jurnal Farmasi Klinik Indonesia Journal Of Vocational Health Studies Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Jurnal Ilmu Kefarmasian Indonesia Majalah Patologi Indonesia Darmabakti Cendekia: Journal of Community Service and Engagements Majalah Biomorfologi (Biomorphology Journal) Jurnal Psikiatri Surabaya (Surabaya Psychiatry Journal) Jurnal Syntax Transformation Indian Journal of Forensic Medicine & Toxicology Jurnal Kesehatan Tambusai Pharmaceutical Sciences and Research (PSR) Jurnal Pengabdian Masyarakat Bhinneka Sewagati Jurnal Pengabdian Masyarakat Bangsa Journal of Clinical Microbiology and Infectious Diseases Folia Medica Indonesiana
Imam Susilo
Departemen Patologi Anatomi, Fakultas Kedokteran Universitas Airlangga RSUD Dr. Soetomo, Jl. Mayjen. Prof. Dr. Moestopo No. 47 Surabaya, Indonesia
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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Journal : Jurnal NERS

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Protein Expression Er (Estrogen Receptor) in Breast Cancer Degree of Malignancy Mild, Moderate, and Severe Imam Susilo
Jurnal Ners Vol. 7 No. 1 (2012): April 2012
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (442.699 KB) | DOI: 10.20473/jn.v7i1.4004

Abstract

Introduction: Mammary carcinoma is the most common malignancy and main mortality cause in women. Hormonal status (ER and PR expression) was long used as patient suitability for hormonal therapy. However, lately there have been many patients with ER and PR negative. This study wanted to prove the relevance of protein expression of ER (estrogen receptor) with the histopathological degree of malignancy of breast invasive ductal cancer and the prognosis of breast cancer with ER protein expression of positive and negative.Methods: In this retrospective and cross sectional analytical study retrieved data about hormonal status (ER expression) and histopathological grading of infiltrating ductal carcinoma patients. This study consisted of 201 patients with mammary carcinoma who referred to medical records Department Pathology Anatomic of Faculty Medicine Airlangga University/Dr. Soetomo General Hospital Surabaya on 1 January 2010–31 December 2010 and their medical record suitable with inclusion criterias. The data was categorized into several groups based on the ER expression result.Results: Most of the sample was in 41–50 year age group (37.31%), and 54,7% of them were in poor expression. The relationship of estrogen receptor (ER) with the degree of histopathology infiltrating ductal carcinoma patients, obtained p-value = 0.001 (p < 0.5) and the 2 × 2 table is only moderate and severe degrees compared with the results of ER expression results obtained p = 0.001 (p < 0.5) and odds ratio of 0.362 (CI: 0194-0675).Conclusion: This study found significant correlation between ER expression with histopathological grading of infiltrating ductal carcinoma patients.
Co-Authors . Heriyawati Abdurahman Abdurrahman Abdurrahman Abdurrahman Adhi Dharma Wibawa, Adhi Dharma Ahmad Yudianto Alphania Rahniayu Anny Setijo Rahaju, Anny Setijo Ardiansyah Ariani, Grace Aziz, Nahdah Aulia Bambang Purwanto Betty Agustina Tambunan Biqisthi Ari Putra Christrijogo Soemartono Waloejo Deshinta Fitrianti Syahida Dwinka Syafira Eljatin DYAH FAUZIAH, DYAH Eko Budi Koendhori, Eko Budi Fadli, Sonny Fajrin, Fifteen A. Ferdinant Martinus Djawa Fifteen A. Fajrin Fifteen Aprila Fajrin Fitriani, Fatimah Nur Fransiska Maria Christianty Furaidah, Erna Gondo Mastutik Hanum, Safa Salsabila Hartawan, M. Wildan Nabalah Haykal, Muhammad Nazhif Hedianto, Tri Hendrarto, Bagus Adjie Dwi Heriyawati, Heriyawati Hidayah, Rizka Nurul I Ketut Suardita Ilmiah, Khafidhotul Indriani, Ratri Dwi Indriastuti, Endah Junaidi Khotib Karimah, Azimatul Karimah, Rumman Khaerana, A. Insyirah KUSUMASTUTI, ETTY HARY Mahardian Rahmadi ManikRetno Wahyunitisari Megawati, Selvi Muhammad Al-Farouq Yufiro Akbar Nahdah Aulia Aziz Nila Kurniasari Nina Mardiana Njoto, Edwin Nugroho Parlindungan, Putra Gelar Prananda S. Airlangga Putra, Bilqisthi Ari Putra, Biqisthi Ari Putra, Gumilar Fardhani Ami Putri Alief Siswanto Putri, Atina Irani Wira Putri, Naomi Lesmana Qonitatillah, Ana Rahmanto, Ilham Raihan Akbar Muhammad Rangkuti, Rahmah Yasinta Rejeki, Purwo Sri Ridhoi, Ahmad Ridholia, Ridholia S.Pd. M Kes I Ketut Sudiana . Safitri, Cahyani Tiara Sakina Sakina Sakina, Sakina Sandi Ardiya Rasitullah Sari, Aditya Sita Sari, Dewi Perwito Semedi, Bambang Pujo Setya Wijoyo, Dhia Lintang Sjahjenny Mustokoweni, Sjahjenny Suharjono, Suharjono, Suharjono Sundari Indah Wiyasihati Syulthoni, Zain Budi Targanski, Constantia Lidwina Utariani, Arie Wahyunitisari, Manik Retno Wardhani, Puspa Willy Sandhika Wirasasmita, Yuyun Wiratama, Priangga Adi Yuri Pamungkas Zavita Anwar