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All Journal Jurnal Sain Veteriner Indonesian Journal of Tropical and Infectious Disease Jurnal Medik Veteriner Journal of Parasite Science Ovozoa: Journal of Animal Reproduction Indian Journal of Forensic Medicine & Toxicology journal of Basic Medical Veterinary Jurnal Riset Rumpun Ilmu Hewani (JURRIH) PCJN Pharmaceutical and Clinical Journal of Nusantara Jurnal Agro Veteriner
Mafruchati, Maslichah
Division Of Veterinary Anatomy, Faculty Of Veterinary Medicine, Universitas Airlangga, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Journal : journal of Basic Medical Veterinary

 1 
PENGARUH PEMBERIAN EKSTRAK KULIT PISANG KEPOK (Musa acuminata) TERHADAP PENURUNAN KADAR MALONDIALDEHID (MDA) PARU MENCIT JANTAN (Mus musculus) YANG DIPAPAR ASAP ROKOK Dewi, Sapna Kurnia; Lokapirnasari, Widya Paramitha; Meles, Dewa Ketut; Mustofa, Imam; Mafruchati, Maslichah; Hamid, Iwan Sahrial
Journal of Basic Medical Veterinary Vol. 8 No. 2 (2019): Journal of Basic Medical Veterinary, December 2019
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/.v8i2.20416

Abstract

This research aimed to determine the effect of kepok banana peel extract (Musa acuminata) given by per oral in decreasing levels of malondialdehyde (MDA) in lung of male mice (Mus musculus) which was exposed to cigarette smoke. The 24 experimental male mice were divided into 6 groups. The therapy was given for 14 days, all mice were sacrificed and lung MDA level were examined with thiobarbituricacid (TBA) methods. The result of the data analysis test using one-way ANOVA (Analysis of Variance) showed that there were significant differences between the group of animals that exposed to cigarette smoke ( = 840.50± 186.47 nmol / g) and the group of animals that were given with extract of kepok banana peel 56 mg / kg bw  ( = 6471.25 ± 69.25 nmol/g). Besides that, there was an significant difference between the groups of animals that were exposed cigarette smoke ( = 840.50± 186.47 nmol / g) with the group of animals that were given with vitamin C 260 mg/kg bw ( = 555.25± 61.16 nmol / g). It could be concluded that extract of kepok banana peel and vitamin C could decrease MDA levels in lung of male mice which was exposed cigarette smoke. The increased therapy dose gave affect in lowering levels of malondialdehyde in lung.
PENGARUH PEMAPARAN KARBOFURAN PADA INDUK MENCIT (Mus musculus) TERHADAP GAMBARAN HISTOPATOLOGI GINJAL ANAK MENCIT MASA LAKTASI Purnomo, Edi; Luqman, Epy Muhammad; Ratnani, Hermin; Plumeriastuti, Hani; Mafruchati, Maslichah; Dhamayanti, Yeni
Journal of Basic Medical Veterinary Vol. 9 No. 1 (2020): Journal of Basic Medical Veterinary, June 2020
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/.v9i1.21095

Abstract

Carbofuran is a broad spectrum carbamat insecticide which is used in various farm practices. An exposure of carbofuran has been reported able to induce Reactive Oxygen Species (ROS) or free radical in kidney. Free radical caused cells damage. The present study was designed to investigate the effect of carbofuran in kidneys histopathologic of mice pup whose dam were exposed by carbofuran during the lactation period. High levels of ROS can bind to various biomolecules such as proteins, lipids and nucleic acids so that carbofuran has a negative effect on tissue functions and structures. Free radical caused changes in the pathological conditions of the tissue including the kidneys. The dams were devided into four groups of five animals each. P0 animal group was received aquadest 0,1 ml per body weight (BW), P1 animal group was treated carbofuran at the dose of 1/16 LD50 (0,3125 mg per BW), P2 animal group was treated carbofuran at the dose of 1/8 LD50 (0, 625 mg per BW), and P3 animal group was treated carbofuran at the dose of 1/4 LD50 (1,25 mg per BW). The carbofuran was exposed via oral postnatal day 1st until 9th postnatal day after delivery. At postnatal day 10th, offspring were sacrified. The kidney of mice pup was collected and processed for microscopic examination with hematoxilin-eosin staining. Microscopic observations on the histology of the mice pup kidney showed an increase in the degree of kidney damage as an increase in the dose of carbofuran given to the dams. The results showed tubular changes in the form of tubular degeneration, inflammatory cell infiltration and tubular necrosis in the kidney of mice pups.
Protection Effectiveness Of Bit (Beta vulgaris) Fruit Extract In Maintaining Spermatogenesis Ability In White Rats (Rattus novergicus) Induced Carbon Tetracloride (CCl4) Anugrah, Alvyan Lantang; Eliyani, Hana; Utomo, Budi; Susilowati, Suherni; Mafruchati, Maslichah; Kurnijasanti, Rochmah
Journal of Basic Medical Veterinary Vol. 10 No. 2 (2021): Journal of Basic Medical Veterinary, December 2021
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbmv.v10i2.31812

Abstract

The aim of this research was to know whether beetroot (Beta Vulgaris) extract could protect spermatogenesis by maintaining spermatogenic and sertoli cell count  in rats (Rattus novergicus) induced with CCl4. Rats were given beetroot extract daily, for 14 days and 3ml/kg BW CCl4 intraperitoneally one hour after last treatment. This study used twenty rats which were devided equally into 5 groups. K(-), the negative control group was not induced with CCL4 and only given 1% CMC-Na suspension. K(+), the positive control group was induced with CCl­4 and given 1% CMC-Na suspension. P1, P2 and P3 were given beet root extract with doses of 200, 400, and 800 mg/kg BW daily before feeding. All of the beetroot treatment were given orally (2 ml). After 24 hours CCl4 induction, rats were sacrificed and testis were collected to make histology slides. The observations showed significantly different (p<0,05) in all of variables. Result showed significant differences in spermatogenic and sertoli cells between K(-) and K(+) groups, K(+) with P2 and P3 group, and showed insignificant difference between P2 and P3 group in spermatogenic and sertoli cells. The result of this research showed that beetroot extract could protect the spermatogenic and sertoli cells in male rats induced with CCl4.
Isolation, Identification and Risk Factors of Escherichia coli Bacteria in Dairy Goat's Milk Subclinical Mastitis in Siliragung District, Banyuwangi Regency Lestari, Dewi Sri; Setiawan, Boedi; Saputro, Amung Logam; Mafruchati , Maslichah; Praja , Ratih Novita; Prastiya, Ragil Angga
Journal of Basic Medical Veterinary Vol. 12 No. 2 (2023): Journal of Basic Medical Veterinary, December 2023
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbmv.v12i2.49401

Abstract

Mastitis is an inflammation of the mammary gland which can cause a decrease in milk production and income for farmers. Subclinical mastitis is mastitis without clinical symptoms but can result in a decrease in the quality of milk production. One of the main pathogens that cause mastitis is Escherichia coli. The risk factors for the occurrence of mastitis, both clinical and subclinical mastitis, can cause a decrease in milk production caused by several factors, including genetic, feed, and environmental factors. This study aims to determine the presence of subclinical mastitis in dairy goat milk in Siliragung District, Banyuwangi Regency. Sample testing was carried out at the SIKIA Instrument Laboratory, Airlangga University. Isolation was carried out using EMBA media (Eosin Methylene Blue Agar) for further identification consisting of Gram staining and biochemical tests. One of the biochemical tests used is the IMViC (Indole Methyl red Voges-Proskauer Citrate Test). The results of isolation, observation of characteristics, and identification of bacteria in the research that was carried out showed that 8% (5/62) of the samples tested were positively identified as Escherichia coli. The results showed that the risk factors for causing subclinical mastitis included cleaning the cage bedding, washing hands before milking, milking out, teat dipping, and medication.
Environmental and Management Risk Factors for Goat Mastitis in Banyuwangi Lestari, Dewi Sri; Setiawan, Boedi; Saputro, Amung Logam; Mafruchati, Maslichah; Praja, Ratih Novita; Prastiya, Ragil Angga
Journal of Basic Medical Veterinary Vol. 14 No. 2 (2025): Journal of Basic Medical Veterinary, December 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbmv.v14i2.49399

Abstract

Mastitis is a persistent and economically significant health problem in dairy goats in Banyuwangi, East Java, where smallholder production systems dominate. This review synthesises current evidence on the primary risk factors contributing to the high prevalence of subclinical mastitis in the region. Local studies consistently report Staphylococcus aureus as the leading etiological agent, frequently exhibiting antimicrobial resistance linked to unsupervised antibiotic use. Host-related factors such as advanced parity, udder lesions, and teat-end damage increase susceptibility to intramammary infection. Management practices—including inadequate milking hygiene, use of shared towels, absence of pre- and post-dipping, and irregular equipment sanitation—facilitate the transmission of contagious pathogens. Environmental conditions, particularly high humidity and poor housing sanitation, further elevate infection pressure. Socio-economic constraints and limited farmer knowledge about subclinical mastitis and antibiotic stewardship exacerbate disease persistence. The multifactorial nature of mastitis in Banyuwangi underscores the need for context-appropriate interventions combining improved hygiene practices, better housing management, routine screening, and responsible antimicrobial use. Strengthened farmer education and targeted surveillance are essential to reduce mastitis prevalence and enhance the sustainability of goat dairy production in the region.
Co-Authors AA Sudharmawan, AA Adiana Mutamsari Witaningrum Al arif, Mohammad Anam Anugrah, Alvyan Lantang Anwar Ma'ruf Asrar, Siti Iqmallisa Nurrill Bachtiar, Harris Yudhanta Boedi Setiawan Budi Utomo Chusniati, Sri Dewi, Sapna Kurnia Eka Pramyrtha Hestianah Emy Koestanti Sabdoningrum Erma Safitri Fadhli Rahman Fauzi Gandul Atik Yuliani Ginta Riady Hana Eliyani Hani Plumeriastuti Hermin Ratnani IMAM MUSTOFA Ira Sari Yudaniayanti Ismudiono Ismudiono Iwan Sahrial Hamid Iwan Sahrial Hamid Jonathan Makuwira Kusnoto Kusnoto, Kusnoto Lestari, Dewi Sri Lokapirnasari, Widya Paramitha Lucia Tri Suwanti, Lucia Tri Luqman, Epy Muhammad Makuwira, Jonathan Meles, Dewa Ketut Mohammad Sukmanadi Mufasirin Muhammad Ilyas Wahyudi Nur, Maysarah Oktavia Praja, Ratih Novita Prastiya, Ragil Angga Rekasni Adallin A/P Morgan A/P Morgan Revina Ayu Septiani Rimayanti Rimayanti Rochmah Kurnijasanti Saputro, Amung Logam Setiawan Koesdarto Shabira, Zahra Sri Hidanah Sri Mulyati Sri Mumpuni Suherni Susilowati Tita Damayanti Lestari Tjuk Imam Restiadi Trilas Sardjito Tyasningsih, Wiwiek Viski Fitri Hendrawan Wahyudi, Nurul Tri Warsito, Sunaryo Hadi Widjiati Widjiati, Widjiati Yeni Dhamayanti