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All Journal Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga. Jurnal Kebidanan Althea Medical Journal Folia Medica Indonesiana Indonesian Journal of Tropical and Infectious Disease Majalah Obstetri dan Ginekologi Public Health of Indonesia Jurnal Ilmiah Kedokteran Wijaya Kusuma Jurnal Penelitian Kesehatan Suara Forikes Health Notions Jurnal Keperawatan Muhammadiyah Amerta Nutrition Care : Jurnal Ilmiah Ilmu Kesehatan Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga JURNAL ILMIAH OBSGIN : Jurnal Ilmiah Ilmu Kebidanan & Kandungan NURSING UPDATE JURNAL ILMIAH ILMU KEPERAWATAN Majalah Biomorfologi (Biomorphology Journal) Indian Journal of Forensic Medicine & Toxicology Jurnal Abdi Masyarakat Indonesia Asian Journal of Health Research Strada Jurnal Ilmiah Kesehatan (SJIK) JURNAL KEPERAWATAN
Hermanto Tri Joewono
Department Of Obstetrics And Gynecology, Faculty Of Medicine, Airlangga University
Humanities Biochemistry, Genetics & Molecular Biology Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Other

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Journal : Care : Jurnal Ilmiah Ilmu Kesehatan

 1 
PUASA PADA KEBUNTINGAN TRIMESTER 1, 2 DAN 3 RELATIF AMAN DILIHAT PADA INDEKS APOPTOSIS SEL NEURON OTAK RATTUS NORVEGICUS BARU LAHIR Wati, Yunita Kholilaili Saras; Joewono, Hermanto Tri; Miftahussurur, Muhammad
Care : Jurnal Ilmiah Ilmu Kesehatan Vol 9, No 2 (2021): EDITION JULY 2021
Publisher : Universitas Tribhuwana Tunggadewi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33366/jc.v9i2.1388

Abstract

Fasting in pregnancy that can increase neural network activity in the brain region and produce BDNF secretions that seek survival pathways will produce pro survival / anti apoptosis in cerebral neuron cells and the cerebellum. The aim of this study to analyze the effect of fasting during pregnancy on the index of apoptosis of cerebral neuron cells and the cerebellum of the newly born Rattus norvegicus. This research was using Experimental laboratory studies that were correct with the post test study design were only the control group design using experimental animals Rattus norvegicus at the Pathology Laboratory of the Faculty of Medicine, Airlangga University Surabaya which were collected into 3 research groups (1st, 2nd, and 3rd trimesters) and 1 control group . Each group consisted of 6 Rattus norvegicus mothers. The brain dissection of the newborn Rattus norvegicus child was taken and the apoptotic index was calculated using the Immunohistochemical Tunnel method. and discuss with the Immunoreactive Score (IRS). The results of the Kruskal wallis analysis were expressed as the Cerebrum apoptosis index in all four groups (p 0.05). Most apoptosis in the cerebrum was in the first trimester (3.9) and lowest in the second trimester (1.5). The results of the cerebellar apoptosis index analysis by the Kruskall wallis test proved that the most cerebellar apoptosis in the first trimester (4.87) and the lowest in the second trimester (1.33). Conclusion there is no difference between the 1,2 th trimester and 3 in the control of the cerebrum and cerebellum
MUSIK MOZART MEMILIKI JUMLAH SEL GLIA TERBANYAK PADA CEREBRUM DAN CEREBELLUM RATTUS NORVEGICUS BARU LAHIR DIBANDINGKAN DENGAN GAMELAN JAWA, SUNDA DAN BALI SELAMA KEHAMILAN Khasanah, Rima Nur; Joewono, Hermanto Tri; Widjiati, Widjiati
Care : Jurnal Ilmiah Ilmu Kesehatan Vol 9, No 2 (2021): EDITION JULY 2021
Publisher : Universitas Tribhuwana Tunggadewi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33366/jc.v9i2.1394

Abstract

Intelligence is one of the basic capital in advancing a country. Efforts that can be done during pregnancy is to provide adequate nutrition and stimulation, stimulation that is easily accepted by the fetus is sound and music is the most harmonious combination of sounds. Analyzing the differences in the number of glia cerebrum cells and the newly born Rattus norvegicus cerebellum from mothers exposed to Mozart music, traditional Javanese gamelan music, Sundanese gamelan, Balinese gamelan and those who were not exposed to music during pregnancy. Experimental research with randomized post-test only control group design. Used by experimental animals Rattus norvegicus as a model of music stimulation. Cutting was done with 10 IU PMSG injection, 10 IU HCG and monomating. randomized into 5 groups. The treatment was given from 10-19 days of pregnancy, for 1 hour in the soundproof room, intensity of 65 Db. Children of Rattus norvegicus were decapitated and dissected by the brain then counted the number of glia cells using Hematoksilin - Eosin and analyzed by statistics. There were significant differences in the number of newly born Rattus norvegicus glia cerebrum cells between groups. Mozart group (25.16 ± 1.72; Astrocytes), (26.16 ± 1.50; Oligodendrocytes) and (21.40 ± 4.27; Microglia) were the highest compared to the control group, Javanese gamelan music, Sundanese, and Bali. Average Number of newborn Rattus norvegicus glia cerebellum cells in the Mozart music group (24.48 ± 3.66; Astrocytes), (19.92 ± 3.77; Oligodendrocytes) and (19.92 ± 3.86; Microglia) the highest compared to control groups, Javanese gamelan music, Sundanese gamelan, and Balinese gamelan. The Mozart exposure group had more glia cerebrum and cerebellum cells than those exposed to Javanese, Sundanese, Balinese gamelan and those who were not exposed to music.
MUSIK MOZART MEMILIKI EKSPRESI SYNAPSIN 1 TERTINGGI PADA CEREBRUM DAN CEREBELLUM RATTUS NORVEGICUS BARU LAHIR DIBANDINGKAN DENGAN GAMELAN JAWA, SUNDA DAN BALI SELAMA KEHAMILAN Yaner, Nurul Ramadhani; Joewono, Hermanto Tri; Widjiati, Widjiati
Care : Jurnal Ilmiah Ilmu Kesehatan Vol 9, No 2 (2021): EDITION JULY 2021
Publisher : Universitas Tribhuwana Tunggadewi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33366/jc.v9i2.1402

Abstract

Stimulation classical music has been shown to influence the increase in brain function and the development of child intelligence. Mozart's classical music has a frequency that can stimulate the growth of synaptic tissue. This research was analyze differences in the expression of synapsin 1 cerebrum and cerebellum Rattus norvegicus was born from mothers exposed to Mozart music, traditional Javanese gamelan music, Sundanese, Balinese and who were not exposed to music during pregnancy. This research was using methods experimental with post test only control group design. The treatment was given to Rattus norvegicus animals from pregnancy day to 10-19, for 1 hour in a soundproof room, intensity of 65 dB. On the 20th day of pregnancy, Rattus norvegicus was sacrificed and 3 of the heaviest, medium and lowest Rattus norvegicus children were selected and the heads of Rattus norvegicus children were decapitated and brain dissection and synapsin 1 expression was calculated using an immunohistochemical method and analyzed with appropriate statistics. Result There were significant differences in the expression of newborn synapsin 1 Rattus norvegicus cerebrum between groups with a value of p = 0.042 (mean in the control group IRS: 2.04 ± 0.26, in the Mozart group IRS: 3.84 ± 1.66, Javanese gamelan group IRS: 2.64 ± 0.51, Sundanese gamelan group IRS: 2.92 ± 0.41, and in the Balinese gamelan group IRS: 2.52 ± 1.18) and so in the cerebellum with a value of p = 0.001 (mean in the control group IRS: 2.02 ± 0.30, in the Mozart group IRS: 4.72 ± 0.54, the Javanese gamelan group was IRS: 3.20 ± 0.82, the Sundanese gamelan group was IRS: 3.12 ± 0.83, and in the Bali gamelan group IRS: 2.08 ± 0.30). Conclusion There are differences in the expression of synapsin 1 of the Rattus norvegicus offspring exposed to Mozart music, gamelan traditional music Javanese, Sundanese and Balinese in the cerebellum but there are no differences in the cerebrum during pregnancy. The highest synapsin expression was in the Mozart group.
Co-Authors Abdullah, Aya Ali Achmad Zam Zam Aghasy Agnes Krisylva Agus Sulistyono Agustina Hidayati Agustina Mar'atus Sholichah Ahmed, Samar A. A. Al-Qadhi, Tasnim Mohammed Aldika Akbar, Muhammad Ilham Ali Madinah Ali Medina Ali Medina Ali, Lamia A. S. Almothana, Hebah H. M. Alselwi, Sarah A. D. Alsoufi, Fardous G. Amila, Ukhti Mukminah ilmi Amishinta, Ancha Ayu Amishinta, Ancha Ayu Ancha Ayu Amishinta Andita Hapsari Andriani, Linda Aprilawati, Dwi Askandar Tjokroprawiro Ayu Putri Yani Binta Dwi Novitasari Chandra, Cecilia Felicia Dedi Kuswandi Dessy Hidayati Fajrin Diana Estu Rumahastuti Dwi Budi Santoso Dwi Nurdi Puspita Sari Dwi Puji Wijayanti Ecccita Raheestyningtyas Eka Fitriani Sujitno Eka Nasrur Maulana Eko Budi Koendhori, Eko Budi Ernawati Ernawati Esti Nugraheny Fajrin, Dessy Hidayati Fitria Desky Frisilia Octaviana Yolanda Gatut Hardianto, Gatut Hafiza Amadhin Rusti Hajj, Suha Ali Al Harry Mangasi Binsar Panjaitan Hasan, Helmia Henky Mohammad Masteryanto HERAWATI, LILIK Herlina Alvianti N Herlina Puji Angesti Herman, Sriyana Heryana, Achmad Yuniari Jihanifa Hega Salsabiila Jimmy Yanuar Anas Khanisyah Erza Gumilar Khasanah, Rima Nur Laksana, Muhammad Ardian Cahya Maramis, Margarita M. Maria Inge Lusida Martono Tri Utomo Mikra Latisfian Mikra Latisfian Mikra Latisfian Mohammed, Haitham T. S. Muhammad Adrianes Bachnas Muhammad Miftahussurur Muhdi, Nalini Nabeel Usama Okbah Nareswari Imanadha Cininta Marcianora Naura Ega Kahayani Nur Cholila Nur Laila Faizah Nurvy Alief Aidillah Nyna Puspa Ningrum Okta Margarita Susiana Pamarga Priyambodo Pitria Permatasari Pudji Lestari PUNGKY MULAWARDHANA, PUNGKY Rejeki, Purwo Sri Rio Wironegoro Risa Etika, Risa Sabrina Kemala Hapsari Sakina Samsriyaningsih Handayani Siti Nur Kholifah Siti Nur Kholifah Siti Nur Kholifah Sofiyanti Miftakhurohmah Sonea Venugopal Sulistiawati Sulistiawati Sulistiawati Sulistiawati Tanadi, Melina Rosita Thabet, Habib Thabit, Riyadh A. S. Ucik Nurul Hidayati Ukhti Mukminah ilmi Amila Ummah, Fithriyah Cholifatul Wardhana, Manggala Pasca Wati, Yunita Kholilaili Saras Widati Fatmaningrum Widjiati Widjiati w Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati, Widjiati Widjiati, DR Widjiati, DR Windhu Purnomo Yaner, Nurul Ramadhani Yanti Yanti Yasyviena Za’ima Elnabila Yulia Putri Permatasari Zumroh Hasanah