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All Journal Farmaka Jurnal Mahasiswa Farmasi Fakultas Kedokteran dan Ilmu Kesehatan UNTAN Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Jurnal Kesehatan Masyarakat JURNAL PHARMASCIENCE Majalah Obat Tradisional Jurnal Pengabdian Kepada Masyarakat (Indonesian Journal of Community Engagement) Journal of Tropical Biodiversity and Biotechnology INDONESIAN JOURNAL OF PHARMACY Pharmascience Edukasi: Jurnal Pendidikan Jurnal Fitofarmaka Indonesia JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Jurnal Epidemiologi Kesehatan Komunitas Al-Khidmah PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) GERVASI: Jurnal Pengabdian kepada Masyarakat Pharmaceutical Journal of Indonesia Jurnal Jamu Indonesia Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang Sasambo Journal of Pharmacy Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Farmasi Komunitas Pharmaceutical Sciences and Research (PSR) Jurnal Natural Jurnal Vokasi Kesehatan Jurnal Pendidikan Kesehatan (e-Journal) Jurnal Sains dan Kesehatan Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Indonesian Journal of Jamu

Eka Kartika Untari

Departemen Farmasi, Fakultas Kedokteran, Universitas Tanjung Pura

Author-ID : 435445

Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Education Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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PENGGUNAAN ANTIBIOTIK OLEH MAHASISWA FAKULTAS KEDOKTERAN UNIVERSITAS TANJUNGPURA (THE USED OF ANTIBIOTIK AT MEDICAL FACULTY OF TANJUNGPURA UNIVERSITY) Herlina, Tutun; Untari, Eka Kartika; Desnita, Rise
Jurnal Mahasiswa Farmasi Fakultas Kedokteran UNTAN Vol 4, No 1 (2019): Jurnal Farmasi Kalbar
Publisher : Jurnal Mahasiswa Farmasi Fakultas Kedokteran UNTAN

Show Abstract | Download Original | Original Source | Check in Google Scholar

The irrational use of antibiotics, either through prescriptionor non-prescription for sel-medication is one of main problems in the health sector through out the world. The role of health worker are the appropriate information source for antibiotic treatment. Method. The research used descriptive observational design, conducted at Medical Faculty of Tanjungpura University. The research subject were student of year 2015 in the faculty. The tool used was a questionnarie, with 32 questions. Result. The knowledge about antibiotics among student of medical faculty is categorized into a good-level (62%), quite-level (15%), and less (23%). Conclusion. From the results of this research was found that there were medical student who had less-level of knowledge about antibiotics and still using antibiotic for self-medication even though the use of antibiotics should be based on a prescription.

Analisis Pengaruh Tingkat Pengetahuan Masyarakat terhadap Tindakan Swamedikasi Diare Akut di Kecamatan Pontianak Timur Robiyanto Robiyanto; Monika Rosmimi; Eka Kartika Untari
Edukasi: Jurnal Pendidikan Vol 16, No 1 (2018): Edukasi: Jurnal Pendidikan
Publisher : LPPM IKIP PGRI Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31571/edukasi.v16i1.845

Penelitian bertujuan untuk: (1) mengetahui ada tidaknya pengaruh karakteristik meliputi usia, jenis kelamin, pekerjaan, dan pendidikan terhadap tindakan swamedikasi diare akut; dan (2) Menganalisis pengaruh tingkat pengetahuan terhadap tindakan swamedikasi diare akut pada masyarakat yang tinggal di Kecamatan Pontianak Timur. Penelitian tergolong penelitian observasional dengan rancangan penelitian potong lintang. Pengambilan sampel dengan metode quota sampling dengan jumlah subjek penelitian sebanyak 60 responden. Teknik pengumpulan data dengan penyebaran kuesioner. Uji statistik data menggunakan chi square test. Kesimpulan dari penelitian menunjukkan bahwa: (1) Usia dan pendidikan memiliki pengaruh terhadap pengetahuan swamedikasi; dan (2) Tingkat pengetahuan responden ternyata berpengaruh terhadap tindakan swamedikasi diare akut.

PENGARUH PEMBERIAN EKSTRAK ETANOL DAUN BUAS-BUAS (Premna cordifolia. LINN) TERHADAP KADAR MDA TIKUS WISTAR JANTAN PASCA PAPARAN ASAP ROKOK Asri Adyttia; Eka Kartika Untari; Sri Wahdaningsih
Jurnal Fitofarmaka Indonesia Vol 1, No 2 (2014): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Free radical from cigarrete smoke can cause lipid peroxidation that could lead to tissue damage. Tissue damage can be identified by increased levels of MDA (Malondialdehyde). Leavesof buas-buas (Premna cordifolia. Linn) has an antioxidant activity in invitro study. This study aimed to analyze the effect of P. cordifolia leaves extract on the levels of malondialdehyde (MDA) after exposure to cigarette smoke. The simplicia extracted by maseration using 70% ethanol. Twenty four wistar strain of Rattus novergicus were divided into six groups , i.e. : normal group without any treatment, positive control group with cigarette smoke exposure and vitamin e treatment, negative control groupwith only cigarette smoke exposure, treatment groupwith cigarette smoke exposure and ethanolic extract from P. cordifolialeaves with doses 200; 400; 600 mg/kg of body weight/day. All rats were treated for 14 days using 3 cigarette non filetered each day. After 14 days, plasma MDA was measured in this research. Measurement of plasma MDA are using Spectrophotometer UV-Vis in 532.2 nm. MDA level in this study was analyzed by the Kruskal-Wallis and Mann-Whitney test. The result showed that plasma MDA level of groupreceived ethanol extract of P. cordifolia leaves doses at 600 mg/kg of body weight/day significantly (p<0.05)lower than negative control group and not significantly differ (p<0.05) to normal group and positive control group.

PENGARUH PEMBERIAN EKSTRAK ETANOL DAUN BAWANG MEKAH (Eleutherine Americana Merr.) TERHADAP KADAR MALONDIALDEHYDE TIKUS WISTAR (Rattus norvegicus) JANTAN PASCA PAPARAN ASAP ROKOK Melda Mery Andiriyani; Eka Kartika Untari; Sri Wahdaningsih
Jurnal Fitofarmaka Indonesia Vol 1, No 2 (2014): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Malondialdehyde (MDA) is a biomarker of lipid peroxidation that is closely correlated with level of oxidative stress. The aim of this study was to know ethanol extract activities from E. americana leaves against blood plasma MDA in male Wistar rats exposed by cigarette smoke using tiobarbituric acid test. The simplicia extracted by maseration using 70% ethanol. Twenty four rats were divided into six groups, i.e. : a normal group, an exposed cigarette smoke (negative) control group, a positive control group and three treatment groups. One normal group received carboxyl methyl cellulose and another groups exposed cigarette smoke during 14 days. Positive control group received vitamin E (18mg/kg BW), and another groups received ethanol extract of E. americana leaves doses 180; 90; 45mg/kg BW, respectively. The MDA level was analysed by spectrophotometer UV-Visible in 532,2 nm. The MDA level statically analysis by Kruskal-Wallis test and following by Mann-Whitney test. The mean MDA levels of normal group, negative control group, positive control group and groups received ethanol extract of E. americana leaves doses 180; 90; 45mg/kg BW were 0,11±0,09; 13,74±2,84; 0,06±0,03; 10,88±2,19; 0,13±0,03; 0,03±0,02 ppm. The mean MDA levels of groups received ethanol extract of E. americana leaves doses at 180; 90mg/kg BW significantly (p<0,05) lower than negative control group. These results show the beneficial effect of ethanol extract of E. americana leaves in the MDA level reducing on the rats that exposed by cigarette.

UJI AKTIVITAS ANTIBAKTERI FRAKSI n-HEKSAN KULIT BUAH NAGA MERAH (Hylocereus polyrhizus Britton & Rose) TERHADAP BAKTERI Staphylococcus aureus ATCC 25923 Sri Amalia; Sri Wahdaningsih; Eka Kartika Untari
Jurnal Fitofarmaka Indonesia Vol 1, No 2 (2014): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Inappropiate antibiotic use was one of the main reason that caused pathogenic microorganism resistance, leads to ineffective treatment. One of those resistance bacteria is Staphylococcus aureus. The research for discovering new antibiotics can help with this issue. The peel of red dragon fruit (Hylocereus polyrhizus) is one of the plants that has antibacterial compounds. The aim of this research is to prove and determine the minimum inhibitory concentration (MIC) value of n-hexane fraction of red dragon fruit’s peel againts Staphylococcus aureus ATCC 25923. The peel was maserated with chloroform, then fractinated by n-hexane. Futhermore, the antibacterial properties of the fraction was tested using Disc Diffusion (Kirby-Bauer) methode with 40, 20 dan 10 mg/mL concentrations. Ampisilin used as control positive. Based on the phytochemical screening of the fraction, the n-hexane fraction of the dragon fruit’s peel contain triterphenoid, steroid and alkaloid. Clear zones produced by 40 mg/mL is 12,80 mm and for 20 mg/mL is 11,17 mm. Wherea concentration 10 mg/mL didn’t show any inhibitory zone. According to this reasearch, the MIC value of the fraction is 20 mg/mL.

PERSEPSI PENYAKIT PADA PASIEN HIVAIDS DENGAN TERAPI ANTIRETROVIRAL MENGGUNAKAN INSTRUMEN BRIEF ILLNESS PERCEPTION QUESTIONNAIRE (B-IPQ) VERSI INDONESIA DI KLINIK CST RSJD SUNGAI BANGKONG PONTIANAK Safitri Caesaria; Robiyanto Robiyanto; Eka Kartika Untari
Farmaka Vol 18, No 3 (2020): Farmaka (November)
Publisher : Fakultas Farmasi, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/farmaka.v18i3.21222

Brief Illness Perception Questionnaire (B-IPQ) merupakan kuesioner untuk menilai persepsi pasien terhadap penyakit kronik yang diderita, salah satunya penyakit Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS). Farmasis memiliki peran penting dalam keberhasilan suatu terapi karena dapat membantu meningkatkan kepatuhan pasien dalam meminum obat Antiretoviral (ARV) agar kadar CD4 dapat ditingkat sekaligus mencegah munculnya gejala infeksi oportunistik. Tujuan dari penelitian ini untuk menentukan persepsi pasien HIV/AIDS di klinik Care Support Treatment (CST) Rumah Sakit Jiwa Daerah (RSJD) Sungai Bangkong Pontianak dan mengetahui jenis ARV dan persentase pasien yang mendapatkan peresepan tersebut. Penelitian ini dilakukan dengan rancangan potong lintang antara Desember 2018 - Januari 2019. Data dikumpulkan menggunakan kuesioner B-IPQ versi Indonesia yang sudah diuji validitas dan realiabilitasnya. Jumlah responden penelitian yang memenuhi kriteria inklusi sebanyak 50 pasien. Hasil penelitian menunjukkan bahwa persepsi pasien HIV/AIDS cenderung negatif dengan skor total 49,56. Jenis ARV yang diresepkan dan persentase pasien yang memperolehnya adalah AZT+3TC+NVP (44%), TDF+3TC+EFV (40%), AZT+3TC+EFV (12%), dan TDF+3TC+NVP (4%). Kesimpulan dari penelitian ini 78% responden (38 pasien) memiliki persepsi negatif terhadap penyakit HIV/AIDS yang dideritanya dan jenis ARV yang paling banyak digunakan adalah kombinasi AZT+3TC+NVP untuk 44% responden.

PENGARUH USIA PASIEN DAN DOSIS TERHADAP EFEK SAMPING METFORMIN PADA PASIEN DIABETES TIPE 2 Anas Putri Maria Natasya Panamuan; Eka Kartika Untari; Shoma Rizkifani
Jurnal Farmasi Komunitas Vol. 8 No. 2 (2021): JURNAL FARMASI KOMUNITAS
Publisher : Universitas Airlangga

Metformin obat lini pertama yang direkomendasikan untuk diabetes melitus tipe 2, metformin memiliki efek samping diawal penggunaan. Efek samping obat tidak dapat dikesampingkan karena dapat menimbulkan berbagai dampak dalam penggunaan obat. Tujuan dari penelitian ini yaitu untuk mengetahui hubungan antara faktor usia dan dosis terhadap risiko efek samping pada penderita diabetes melitus tipe 2. Penelitian ini merupakan penelitian observasional dengan rancangan penelitian potong lintang. Sampel yang digunakan pada penelitian ini yaitu penderita DM 2 yang menggunakan metformin sebagai antidiabetes. Teknik pengambilan sampel yaitu purposive sampling dengan sampel sebanyak 54 responden yang memenuhi kriteria inklusi dan eklusi. Analisis uji chi square digunakan untuk menghubungkan antara dua variabel. Variabel dari penelitian ini yaitu faktor usia, dosis dan risiko efek samping. Hasil penelitian didapatkan bahwa terdapat hubungan yang signifikan antara faktor usia terhadap risiko efek samping dengan p-value 0,033 oods ratio sebesar 6,908, setelah usia 30 tahun mulai terjadi penurunan kemampuan ginjal, sehingga menyebabkan proses eliminasi dari metformin tidak berjalan dengan baik yang menyebabkan terjadinya efek samping. Faktor dosis terhadap risiko efek samping juga memiliki hubungan yang signifikan dengan p-value 0,000 oods ratio sebesar 20,614, semakin tinggi dosis yang digunakan risiko efek samping akan semakin tinggi karena berhubungan dengan kadar obat dalam darah.

A study of hemodynamic medicine use in intensive cardiac care unit of dr. Soedarso regional public hospital, Pontianak Shoma Rizkifani; Intan Khairunnisa; Eka Kartika Untari
Media Farmasi: Jurnal Ilmu Farmasi Vol 19, No 1: March 2022
Publisher : Universitas Ahmad Dahlan

Hemodynamic medicines are important to recover patients with a critical period in the ICCU. Hemodynamic medicines have a small range of dose so that it has a large effect on the therapy. Therefore, a study on the use of hemodynamic medicines and doses is necessarily conducted. This study aims to investigate the use and doses of hemodynamic medicines administered to patients in the ICCU of dr. Soedarso Hospital Pontianak. This study is observational research with a descriptive cross-sectional design. The research sample was 49 patients who had met the inclusion criteria. The data were analyzed descriptively to describe the frequency and percentage. The results show that a single hemodynamic medicine is administered to 65% of the patients and a combination of hemodynamic medicines is administered to 35% of the patients. The single medicine refers to dobutamine administered to 84.4% of the patients. Meanwhile, the combination of hemodynamic medicines consists of dobutamine and norepinephrine that are administered to 52.9% of the patients. The doses of hemodynamic medicines frequently administered to patients are 3-5 Î¼g/kg/min dobutamine, 3-10 Î¼g/kg/min dopamine, 0.01-2-2 Î¼g/kg/min norepinephrine, and 1 mg/ml epinephrine. This study concludes that dobutamine (inotropic) is the most frequently used single hemodynamic medicine, and norepinephrine (vasopressor) is the most frequently used combined hemodynamic medicine for the ICCU patients at dr. Soedarso Regional Public Hospital, Pontianak.

ANTIBACTERIAL ACTIVITY TESTING OF N-HEXANE FRACTION OF RED DRAGON (Hylocereus polyrhizus Britton & Rose) FRUIT PEEL ON Staphylococcus aureus ATCC 25923 Sri Amalia; Sri Wahdaningsih; Eka Kartika Untari
Majalah Obat Tradisional Vol 19, No 2 (2014)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Inappropiate antibiotic use was one of the main reason that caused pathogenic microorganism resistance, leads to ineffective treatment. One of those resistance bacteria is Staphylococcus aureus. The research for discovering new antibiotics can help with this issue. The peel of red dragon fruit (Hylocereus polyrhizus) is one of the plants that has antibacterial compounds. The aim of this research is to prove and determine the clear zone value of n-hexane fraction of red dragon fruit’s peel againts Staphylococcus aureus ATCC 2593. The peel was maserated with chloroform, then fractinated by n-hexane. Futhermore, the antibacterial properties of the fraction was tested using Disc Diffusion (Kirby-Bauer) methode with 20 and 40 mg/mL concentrations. Ampicillin used as control positive, and Dymetil sulfoxida (DMSO) used as control negative . Based on the phytochemical screening of the fraction, the n-hexane fraction of the dragon fruit’s peel contain terpenoid and alkaloid. Clear zones produced by 40 mg/mL is 12.80±1,69 mm and for 20 mg/mL is 11.17±1,11 mm.

Increasing Knowledge and Promoting Better Attitude towards Appropriate Self-Medication in Sungai Ambawang Community through CBIA eka kartika untari; Robiyanto Robiyanto; Pratiwi Apridamayanti; Muhammad Akib Yuswar; Rafika Sari; Nera Umilia Purwanti; Ressi Susanti
Jurnal Pengabdian kepada Masyarakat (Indonesian Journal of Community Engagement) Vol 7, No 2 (2021): June
Publisher : Direktorat Pengabdian kepada Masyarakat Universitas Gadjah Mada

Self-medication practice in the community tends to increase. One of the factors that influence this trend is the variation of non-prescription drugs and advertisements. Although in self-medication people are allowed to determine their own medication, but it has the potential to create problems. Sungai Ambawang Sub-district is one of the trans Kalimantan; accordingly the medicine products from outside West Kalimantan can be transported through this area. This community service activity (PKM) aimed to increase knowledge and encourage positive attitudes, so that their behavior of self-medication becomes appropriate. This PKM was carried out by the method of communitybased interactive approach (CBIA) in 2 steps. This activity involved 66 community health center cadres. The participants’ knowledge and attitude were measured twice (pretest and posttest) through questionnaires, then analyzed descriptively and statistically using the Wilcoxon test. The observations showed that most of the participants had bought medicines without a prescription for self-medication (78.7%), obtained the medicine from pharmacies (65.2%), purchased medicines over the counter (45.4%), and frequently used analgesic-antipyretics (77%). The results of the Wilcoxon test showed that there were significant differences between knowledge and attitudes before and after CBIA intervention. Based on the results of this intervention, it was concluded that the CBIA intervention done as the PKM activity could increase knowledge and encourage positive attitudes regarding appropriate self-medication practices.

Co-Authors A.A. Ketut Agung Cahyawan W Agilina, Alvani Renata Agustia Damayanti Agustia Damayanti Agustia Damayanti Agustia Damayanti, Agustia Alvani Renata Agilina Anas Putri Maria Natasya Panamuan Apridamayanti, Pratiwi Asri Adyttia Asri Adyttia Asri Adyttia Asri Adyttia, Asri Ayu Pratiwi Butarbutar, Ruth Haryati Ediati Sasmito Egida Rachmadani Gamayanti, Tasiana Gisela Hadi Kurniawan, Hadi Hati, Anita Kumala Herlina, Tutun Intan Khairunnisa Irene Mahwal Khairunnisa, Intan Kusuma, Ria Liberti, Oktaviona Winda Meilita, Dewi Melda Mery Andiriyani Monika Rosmimi Muhammad Akib Yuswar Muhammad Akib Yuswar Muhammad Akib Yuswar Muhammad Akib Yuswar Nabilla Putri Pratiwi Nanang Munif Yasin Nera Umilia Purwanti, Nera Umilia Niken Larasati Novi Permata Sari Nurmainah Nurmainah Nurul Mar'atus Sholihah Octaviani, Peppy Oskar Skarayadi, Oskar Pinasti Utami, Pinasti pramestutie, hananditia rachma Pratiwi Apridamayanti Pratiwi Apridamayanti, Pratiwi Pratiwi, Nabilla Putri Rachmadani, Egida Rafika Sari Rafika Sari Rafika Sari Ratna Widyaningrum Ria Kusuma Rise Desnita, Rise Rizka Humardewayanti Asdie Robiyanto Robiyanto, Robiyanto Robiyanto, Robiyanto Rosmimi, Monika Ruth Haryanti Butarbutar Safitri Caesaria Samudra, Nizam Elang Sholihah, Nurul Mar'atus Shoma Rizkifani Siti Nani Nurbaeti Sri Amalia Sri Amalia Sri Amalia, Sri Sri Mulyaningsih Sri Wahdaningsih Sri Wardaningsih Susanti, Ressi Susanti, Ressi Tri Murti Andayani Vanie, Vanie Veronika, Vina Wirna Maya Sari Wirna Maya Sari Wirna Maya Sari Wirna Maya Sari, Wirna Maya Yunita Fauziah Yunita Fauziah Yunita Fauziah Yunita Fauziah, Yunita Yuswar, M. Akib Yuswar, Muhammad Akib

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