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Telaah Kualitas Hidup Pasien Penyakit Kronik di Kalimantan Barat Untari, Eka Kartika; Yuswar, Muhammad Akib; Rizkifani, Shoma
Jurnal Epidemiologi Kesehatan Komunitas Vol 9, No 2 : Agustus 2024
Publisher : Master of Epidemiology, Faculty of Public Health, Diponegoro University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jekk.v9i2.12295

Background: The long duration of chronic disease affecting the patient’s quality of life. Every disease including chronic disease has a different duration and prognosis. The instrument that being used in measuring the quality of life can be very important factor. Quality of life assessment has a benefit by evaluate the treatment of patients with chronic disease, moreover the good quality of life will also increase the patient's life expectancy. The purpose of this article are to describe and identify instruments that being used to measure quality of life patients with chronic disease in West Kalimantan.Methods: This study conduct to review the original research articles with the keywords "quality of life", "chronic disease", and "West Kalimantan". Twenty three research articles were obtained in Google Scholar and met the inclusion criteria. The generic instruments such as WHOQOL-BREF and EQ5D are the most widely used to measure the patient’s quality of life.Result: The distribution of chronic diseases that have been assessed were hypertension, chronic renal failure, diabetes mellitus, COPD, pulmonary tuberculosis, asthma, myocardial infarction, stroke, CHD, osteoarthritis, HIV / AIDS, and psoriasis. The disease with the most impact on quality of life is hypertension (6 of 23 articles). There were 53.07% patients has a good quality of life; 15.97% patients has a moderate quality of life; and 30.96% patients has a bad quality of life.Conclusion : Most of the hypertensive patients has a good quality of life compared to other disease groups. Health interventions were needed to improve the quality of life for patients with chronic diseases.

Insurance, Policy, Knowledge Level and Epidemiology As Factors Affecting Demand And Supply of Pharmaceutical Product Cahaya, Noor; Pramestutie, Hananditia Rachma; Hati, Anita Kumala; Untari, Eka Kartika; Utami, Pinasti
Pharmaceutical Journal of Indonesia Vol. 7 No. 2 (2022)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.pji.2022.007.02.2

Fulfillment of drug availability is always a challenge from year to year and is determined by supply and demand issues for pharmaceutical drugs. Good management of drugs and pharmaceutical supplies is important in health services. This is related to the quality of health services and the efficiency and effectiveness of the budget. This review study aims to examine the factors that influence drug supply and demand simultaneously with a different perspective from other studies, namely, the focus is to simultaneously discuss the effects of health insurance financing schemes, registration regulations for pharmaceutical products and imports of pharmaceutical products, the level of pharmacist knowledge, changes in disease patterns, disasters, and wars on drug supply and demand. The research design that was used in this study is a narrative review. The data sources that were used are PubMed, Science Direct, Scopus, and Google Scholar. The inclusion criteria in this study are all research related to the demand for pharmaceutical supplies and drugsthat will be reviewed in the study, either in the form of original research, reviews, or reports. The results obtained articles consisting of 8 articles related to health insurance financing, 6 articles related to registration regulation of pharmaceutical products and import of pharmaceutical products, 5 articles related to pharmacist knowledge level, 3 articles related to changes in disease patterns, and 3 articles related to disasters and wars. Based on the 25 articles that were used as data in this study, it was found that the factors that influence the supply and demand of pharmaceutical supplies are health insurance financing, regulation of registration drug processes and imports of pharmaceutical products, level of knowledge of pharmacists as pharmaceutical service providers, changes in disease patterns, disasters, politics, and war.

Hypoglycemia in Geriatric Patients with Diabetes: A Review Untari, Eka Kartika; Yuswar, Muhammad Akib
Pharmaceutical Journal of Indonesia Vol. 9 No. 2 (2024)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.pji.2024.009.02.3

Background: The prevalence of diabetes tends to be high, 42% of geriatric patients admitted havea diabetes diagnosis, and 33% of these patients experience hypoglycemia. Hospitalization isnecessary for diabetic elderly individuals because their blood glucose levels make themmore vulnerable to other complications. The incidence of hypoglycemia in geriatric patients maybe caused by a variety of factors, including polypharmacy, pharmacokinetic andpharmacodynamic changes, hormonal regulation disorders, food and water intake disturbances,decreased intestinal absorption, and cognitive disorders, as well as other organ disorders that causedisruption of the ability to metabolize antihyperglycemia.Methods: This review will go over how frequently geriatricians, especially those withdiabetes, develop hypoglycemia as a result of using anti-diabetics or other medications thatlead to drop blood sugar.Results: Sulfonylurea and insulin groups are the most frequent causes of hypoglycemia indiabetic older people, according to the articles we analyzed. The significance of specific carefor the elderly population in order to lessen the effects of hypoglycemia.Conclusions: For geriatric individuals with DM, routine blood glucose monitoring is advisedto prevent diabetic complications.

Insurance, Policy, Knowledge Level and Epidemiology As Factors Affecting Demand And Supply of Pharmaceutical Product Cahaya, Noor; Pramestutie, Hananditia Rachma; Hati, Anita Kumala; Untari, Eka Kartika; Utami, Pinasti
Pharmaceutical Journal of Indonesia Vol. 7 No. 2 (2022)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.pji.2022.007.02.2

Fulfillment of drug availability is always a challenge from year to year and is determined by supply and demand issues for pharmaceutical drugs. Good management of drugs and pharmaceutical supplies is important in health services. This is related to the quality of health services and the efficiency and effectiveness of the budget. This review study aims to examine the factors that influence drug supply and demand simultaneously with a different perspective from other studies, namely, the focus is to simultaneously discuss the effects of health insurance financing schemes, registration regulations for pharmaceutical products and imports of pharmaceutical products, the level of pharmacist knowledge, changes in disease patterns, disasters, and wars on drug supply and demand. The research design that was used in this study is a narrative review. The data sources that were used are PubMed, Science Direct, Scopus, and Google Scholar. The inclusion criteria in this study are all research related to the demand for pharmaceutical supplies and drugsthat will be reviewed in the study, either in the form of original research, reviews, or reports. The results obtained articles consisting of 8 articles related to health insurance financing, 6 articles related to registration regulation of pharmaceutical products and import of pharmaceutical products, 5 articles related to pharmacist knowledge level, 3 articles related to changes in disease patterns, and 3 articles related to disasters and wars. Based on the 25 articles that were used as data in this study, it was found that the factors that influence the supply and demand of pharmaceutical supplies are health insurance financing, regulation of registration drug processes and imports of pharmaceutical products, level of knowledge of pharmacists as pharmaceutical service providers, changes in disease patterns, disasters, politics, and war.

Hypoglycemia in Geriatric Patients with Diabetes: A Review Untari, Eka Kartika; Yuswar, Muhammad Akib
Pharmaceutical Journal of Indonesia Vol. 9 No. 2 (2024)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.pji.2024.009.02.3

Background: The prevalence of diabetes tends to be high, 42% of geriatric patients admitted havea diabetes diagnosis, and 33% of these patients experience hypoglycemia. Hospitalization isnecessary for diabetic elderly individuals because their blood glucose levels make themmore vulnerable to other complications. The incidence of hypoglycemia in geriatric patients maybe caused by a variety of factors, including polypharmacy, pharmacokinetic andpharmacodynamic changes, hormonal regulation disorders, food and water intake disturbances,decreased intestinal absorption, and cognitive disorders, as well as other organ disorders that causedisruption of the ability to metabolize antihyperglycemia.Methods: This review will go over how frequently geriatricians, especially those withdiabetes, develop hypoglycemia as a result of using anti-diabetics or other medications thatlead to drop blood sugar.Results: Sulfonylurea and insulin groups are the most frequent causes of hypoglycemia indiabetic older people, according to the articles we analyzed. The significance of specific carefor the elderly population in order to lessen the effects of hypoglycemia.Conclusions: For geriatric individuals with DM, routine blood glucose monitoring is advisedto prevent diabetic complications.

Clinical Trial of Bawang Dayak Leaves Capsules (Eleutherine americana) in Active Smokers Wahdaningsih, Sri; Untari, Eka Kartika; Rizkifani, Shoma
Majalah Obat Tradisional Vol 29, No 2 (2024)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.86496

Smoking is an unhealthy behavior, particularly for the respiratory system's health due to the free radicals found in cigarette smoke. Eleutherine americana or Bawang Dayak has antioxidant properties which can neutralize the harmful free radicals penetrating the body. Additionally, malondialdehyde (MDA) is one of the stress oxidative biomarkers often applied to identify reactive stress. This study was conducted to determine the effect of Malondialdehyde on active smokers who consumed Bawang Dayak Leaves capsules. This study was a pre and post-test design involving 30 smokers who met the inclusion. The participants consumed 1 capsule containing 400 mg Bawang Dayak leaves extract for 7 days. The subject's blood was taken before and after the consumption of the capsules for MDA examination. The results of this study were that the MDA level between before and after Bawang Dayak capsules consumed statistically significant. Moreover, MDA pre and post-test level respectively were 12.074 nmol/ml and 11.869 nmol/ml. The usage of Bawang Dayak leaves capsules for a week can reduce MDA levels and likely has an antioxidant potential for active smokers.

Perbandingan Statin Terhadap Kejadian Efek Samping Terkait Myalgia: Comparison of Statins to Side Effect Events Related Myalgia Irene Mahwal; Eka Kartika Untari; Nurmainah Nurmainah
Jurnal Sains dan Kesehatan Vol. 4 No. 2 (2022): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v4i2.906

Statin adalah golongan hiperlipidemia yang paling umum dilaporkan terkait kejadian myalgia dengan dosis 10-80 mg/hari. Kejadian myalgia yang diinduksi statin menjadi perhatian bagi peneliti, mengingat jumlah pasien hiperkolesterolemia yang menggunakan terapi statin cukup tinggi. Penelitian bertujuan untuk mengetahui golongan statin yang berpotensi menyebebkan kejadian myalgia serta untuk mengetahui tingkat keparahan myalgia akibat penggunaan statin, sehingga dapat meningkatkan kewaspadaan masyarakat dalam mengatasi kejadian efek samping akibat penggunaan statin. Metode penelitian menggunakan desain observasional analitik cross-sectional, dengan instrumen pengumpulan data menggunakan kuesioner FIQR dalam bentuk google form. Hasil penelitian menunjukkan kasus myalgia paling banyak ditemui pada responden yang berusia 36-45 tahun (26,08 %), dan kejadian paling sedikit terjadi pada pasien > 65 tahun (8,69 %). Hasil data distribusi jenis kelamin, perempuan memiliki prevalensi sebesar 56,52 % dan laki-laki sebesar 43,47 %. Golongan statin yang digunakan oleh responden penelitian adalah simvastatin dengan presentase sebesar 58,69 %, sedangkan responden yang menggunakan atorvastatin dengan presentase 41,30 %. Kejadian myalgia yang dialami oleh responden memiliki tingkat keparahan ringan dengan proporsi sebanyak 43 orang, hingga sedang dengan proporsi 3 orang. Kesimpulan dari penelitian ini adalah golongan statin yang berpotensi menyebabkan kejadian myalgia yaitu, simvastatin dan atorvastatin, dengan tingkat keparahan myalgia yaitu ringan hingga sedang.

IDENTIFIKASI DAMPAK INTERAKSI OBAT ANTIHIPERTENSI TERHADAP TEKANAN DARAH PADA PASIEN GERIATRI HIPERTENSI YANG DIRAWAT INAP DI RSUD DR SOEDARSO PONTIANAK Muhammad Akib Yuswar; Egida Rachmadani; Eka Kartika Untari
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 1 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i1.524

Hypertension is one of cardiovascular diseases in geriatrics. Hypertensive geriatric patients require a combination of more antihypertensives to achieve blood pressure targets, it can cause high risk of polypharmacy. Polypharmacy in hypertensive geriatric patients is at high risk of drug interactions that can affect their blood pressure. This study aims to identify the interactions of antihypertensives based on mechanism and severity and also to determine whether there is a change in blood pressure caused by drug interactions in geriatric hypertensive inpatients at RSUD Dr Soedarso on January – June 2019. Data were collected retrospectively from 38 patients’ medical records, using total sampling technique. Data were analyzed descriptively using E-book Stockley’s Drug Interaction and Drug Interaction Checker on medscape.com, drugs.com. There were 28 patients (73%) who may experience drug interactions with a total of 85 cases. Drug interactions with moderate severity and pharmacodynamic interaction mechanism often occur in a row were 61 cases (72%) and 79 cases (93%). There were a decrease and increase blood pressure, which in a row were 23 and 4 patients. The decrease of patients’ blood pressure estimated caused by synergistic drug interactions of antihypertensives and adjustment of each drug dose that has potential to increase blood pressure.

Direct Medical Costs of Diabetes and the Foot Ulcer Outpatients in A General Hospital, Yogyakarta Untari, Eka Kartika; Andayani, Tri Murti; Yasin, Nanang Munif; Asdie, Rizka Humardewayanti
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 15, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.90615

Background: In addition to the financial burden that Diabetes Mellitus (DM) places on diabetics and their families due to the complications of Diabetic Foot Ulcers (DFU), treatment costs are escalating. Along with the costs associated with diabetic impairments, direct medical costs may contribute significantly to the financial burden of diabetes.Objectives: This study aimed to determine expenditures associated with DFU, identify cost-influencing factors, and compare the costs of patients with DFU and those without ulcers.Methods: To achieve this objective, this study employed a cross-sectional design and included 198 medical records of DM patients who met the following criteria: age range of 18 to 60 years; type 1 or type 2 DM; receipt of anti-diabetics; payment information; absence of autoimmune or end-stage chronic disease; and absence of corticosteroid. The significance of the cost difference between DFU and non-ulcer patients was evaluated using parametric and non-parametric tests as well as linear regression analysis to determine the cost-influencing factors.Results: This study included 188 patients with type 2 diabetes and ten patients with type 1 diabetes. A total of 131 people with diabetes did not have ulcers, while 67 had a history of DFU. The average direct medical expenses for patients with DFU are IDR 760,146.32, compared to IDR 542,51.24 for patients without ulcer.Conclusion: The presence of ulcers and glycemic conditions had an effect on the direct costs; insulin use also affected the direct costs. The direct costs of diabetic ulcer were significantly higher than non-ulcer, and they were predominantly affected by insulin prescribing.

Evaluasi Tingkat Pengetahuan Mahasiswa Pendidikan Profesi Apoteker UNTAN melalui Kegiatan Matrikulasi Kurniawan, Hadi; Untari, Eka Kartika
Jurnal Pendidikan Kesehatan (e-Journal) Vol. 11 No. 1 (2022): Jurnal Pendidikan Kesehatan (E-Journal)
Publisher : Poltekkes Kemenkes Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31290/jpk.v11i1.2309

Matriculation is a series of activities to welcome new students and institutional service for new students whereas they are accepted not only from alumni of Tanjungpura University with diverse backgrounds, especially academic and social abilities. This activity is needed to uniform and to harmonize academic skills and support students readiness in Pharmacist Professional Education Study Program at University of Tanjungpura, so the students are expected to pass the educational process and to pass the competency test. In addition, to refresh and to increase the knowledge and understanding of new students when they attend lectures, providing to new students already have a basic concept of knowledge that will be studied in pharmacist professional education. The method used was one group pretest-posttest design. The results of the activity showed that matriculation can increase and affect the value of student learning outcomes significantly with the pretest average score indicator at 46.35933 (scale 0 until 100) to 65.89633 (scale 0 until 100) of post-test average score. The results of filling out the questionnaire indicated that this activity was considered very useful and hoped that the activity would be continuing.

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