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Ketoprofen-Tromethamine: Binary Phase Diagram of Multicomponent Crystal, Dissolution Rate, and Analgesic Activity Evaluation Hasanah, Uswatul; Badriyya, Elsa; Safitri, Reza; Yuliza, Sukma; Ihsan, Ikhwanul; Saafrida; Rosaini, Henni; Jessica, Adhitya; Zaini, Erizal
Science and Technology Indonesia Vol. 9 No. 3 (2024): July
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2024.9.3.726-734

Abstract

Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) whose formulation options are limited due to its low dissolution rate in aqueous media. This research aimed to enhance the solubility of ketoprofen in distilled water and to compare the anti-inflammatory and analgesic effects of its resulting multicomponent crystal with tromethamine. The binary phase diagram of ketoprofen-tromethamine was created across molar ratios ranging from 1:9 to 9:1. The multicomponent crystal comprising ketoprofen and tromethamine in the selected ratio was synthesized using a solvent drop grinding method and subjected to further characterization for thermal properties, crystallinity, chemical groups, and morphology. The dissolution rate assessments were evaluated in CO2-free distilled water. Pharmacological analyses examined the anti-inflammatory and analgesic effects of the multicomponent crystal. The binary phase analysis identified the 5:5 (1:1) molar ratio as optimal in forming a multicomponent crystal. Thermograms and diffractograms revealed crystalline alterations attributed to a new crystalline phase. The new multicomponent crystal exhibited approximately 2.7 times higher dissolution rate after 30 minutes, outperforming pure ketoprofen. Pharmacological assessments demonstrated superior analgesic effects of the multicomponent crystal. In summary, the ketoprofen-tromethamine cocrystal in 1:1 molar ratio offers enhanced dissolution rate and provides better analgesic activity than ketoprofen alone.
Impact of Communication Technology on Student Behavior During Lectures Rachmat Kriyantono; Reza Safitri; Noveria Anggraeni Fiaji; Wisnu Wijanarko; Nanang Krisdinanto; Rohmah Nia Chandra Sari; Monica Trivena Nainggolan; Muhammad Hafidz Daros Airlangga; Atma Amanda Putri
Jurnal ILMU KOMUNIKASI Vol. 21 No. 2 (2024)
Publisher : Departemen Ilmu Komunikasi FISIP Universitas Atma Jaya Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/jik.v21i2.7634

Abstract

Technological advancements have impacted education, influencing student behavior across different eras—1990s, 2000s, and today. This survey-based research uses conventional sampling techniques and supports the theory of technological determinism, showing how communication technology affects behavior, thought patterns, and social interactions. Face-to-face communication has largely been replaced by online interactions. The study finds that chatting remains a common activity while waiting for lecturers, and highlights a decline in reading habits. Instead, frequent use of mobile phone has become prevalent. The research underscores how technology reshapes both learning environments and student habits.
Employee Perceptions and Competences in Batam City Private Companies Facing Digital Finance Development Indrayani, Indrayani; Putri Sadayi, Delila; Eleonora Rumengan, Angelina; Safitri, Reza
International Journal of Artificial Intelligence Research Vol 6, No 1.2 (2022)
Publisher : STMIK Dharma Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29099/ijair.v6i1.2.913

Abstract

The transformation and development of digital finance have become an important issue in today's business world. Private companies in Batam City are also experiencing the impact of this transformation. This study aims to analyze employee perceptions and competencies in dealing with the transformation and development of digital finance in private companies in Batam City. This research focuses on understanding how employees perceive digital financial transformation and to what extent they have the necessary competencies to adapt to these changes. This study interviews and observes Batam City private company employees for qualitative data analysis. The systematic analysis was analyzed the data. This study found that most employees see digital finance transition positively. Digital finance may improve efficiency, engagement, and financial information accessibility. This research also finds different employee challenges in digital finance transformation. One is a need for digital technology and financial competence. Employees need help to adapt and maximize digital finance's potential. Thus, employee proficiency in digital financial transformation requires training and skills development. This study offers light on Batam City private company employees' views of digital finance's evolution. Positive impressions suggest digital finance can boost employee productivity and participation in firm financial tasks. However, training and skills development must overcome competency issues. Thus, organizations must focus on personnel development throughout digital financial transformation to ensure business success and continuity.
CITY BRANDING: PERSPEKTIF EVENT SEBAGAI SIMBOLIS PADA FESTIVAL PACU JALUR KABUPATEN KUANTAN SINGINGI, RIAU Trida, Mutiara; Safitri, Reza; Prasetyo, Bambang Dwi
Jurnal Riset Mahasiswa Dakwah dan Komunikasi Vol 6, No 3 (2024)
Publisher : Universitas Islam Negeri Sultan Syarif Kasim Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24014/jrmdk.v6i3.31262

Abstract

Penelitian ini membahas mengenai peran festival pacu jalur yang merupakan identitas daerah dapat dimanfaatkan sebagai alat city branding. Tujuan penelitian ini untuk mengeksplorasi peran Festival Pacu Jalur sebagai simbolisme dalam pembentukan city branding Kabupaten Kuantan Singingi, serta peran pemangku kepentingan (model pentahelix). Paradigma penelitian yang digunakan yaitu konstruktivistik dengan pendekatan kualitatif deskriptif, data dikumpulkan melalui observasi, wawancara, dan dokumentasi dengan melibatkan informan pemangku kepentingan berdasarkan model pentahelix yang meliputi lima aktor yaitu pemerintah, akademisi, pelaku bisnis, komunitas, dan media. Analisis data dilakukan melalui tahapan kondensasi data, penyajian data, dan verifikasi penarikan kesimpulan. Hasil penelitian menunjukkan bahwa Festival Pacu Jalur memiliki peran yang sangat penting dalam pembentukan city branding Kabupaten Kuantan Singingi, dengan memperkuat identitas budaya lokal, meningkatkan daya tarik pariwisata, memberikan peluang pada perekonomian lokal, dan peningkatan infrastruktur. Serta peranan pemangku kepentingan memiliki keterlibatan yang signifikan dalam proses pembentukan city branding Kabupaten Kuantan Singingi dengan memanfaatkan Festival Pacu Jalur.
Penyuluhan: Mampukah Menghadirkan Perubahan? Satriawan, Pravasta Wahyu; Hanim, Faridha; Safitri, Reza; Sawitri, Budi
AGRIEKSTENSIA Vol 22 No 1 (2023): AGRIEKSTENSIA: Jurnal Penelitian Terapan Bidang Pertanian
Publisher : Politeknik Pembangunan Pertanian Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34145/agriekstensia.v22i1.2560

Abstract

Partisipasi masyarakat dalam pengelolaan wisata desa, menjadi tolok ukur keberhasilan suatu penyebaran informasi oleh agen pembaharu atau penyuluh. Tujuan penelitian ini antara lain 1) mengidentifikasi karakteristik inovasi wisata Bon Deso dan 2) mendesain rancangan penyuluhan guna memberikan kesadaran petani Desa Tulungrejo terhadap pentingnya pengembangan wisata Bon Deso. Penelitian ini menggunakan pendekatan action-research untuk mendapatkan pengetahuan sekaligus mengambil tindakan untuk menciptakan perubahan perilaku pada Petani. Penelitian ini berlokasi di wisata Bon Deso, Desa Tulungrejo, Kota Batu. Informan dalam penelitian ini terdiri dari 6 orang dengan 1 sebagai key informan yang ditetapkan secara purposive serta 5 sebagai informan tambahan yang ditetapkan dengan snowball sampling. Wawancara mendalam dilakukan untuk mengeskplorasi permasalahan sehingga dapat ditentukan perencanaan, pelaksanaan, dan evaluasi. Analisa dilakukan secara deskriptif untuk menjabarkan fenomena yang terjadi. Hasil penelitian menunjukkan bahwa Wisata Bon Deso sesuai dengan karakteristik sosial-ekonomi masyarakat dan lingkungan, dapat diamatiidan dicoba. Akan tetapi, wisata tersebut belum memberikan keuntungan sebab belum beroperasi dan mengalami kendala berupa lemahnya dukungan dari stakeholder terkait. Pada aspek perancangan penyuluhan, penetapan tujuan, sasaran, materi, metode, serta media dinilai efektif karena hasil evaluasi menunjukkan terjadi peningkatan pengetahuan secara signifikan dari petani. Rekomendasi penelitian ini yaitu melakukan tindakan persuatif dan memfasilitasi petani dalam memahami konsep wisata berkelanjutan.
Kandang Komunal: Sebuah Model Inovasi Peternakan Sapi Perah (Studi Kasus Kelompok Tani Gunung Harta dan Wonorejeki) Ningtias, Iin; Satriawan, Pravasta Wahyu; Arief, Muhammad Dimas Sulthan; Safitri, Reza
AGRIEKSTENSIA Vol 22 No 1 (2023): AGRIEKSTENSIA: Jurnal Penelitian Terapan Bidang Pertanian
Publisher : Politeknik Pembangunan Pertanian Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34145/agriekstensia.v22i1.2828

Abstract

Keterbatasan kepemilikan luasan lahan pertanian merupakan permasalahan yang sering dihadapi petani dalam menjalankan usahataninya. Kondisi tersebut juga terjadi pada sektor peternakan terutama peternak yang memelihara sapi. Kehadiran kandang komunal merupakan sebuah inovasi dengan tujuan memusatkan hewan ternak pada suatu wilayah. Penelitian ini bertujuan untuk menganalisa proses adopsi peternak sapi perah terhadap inovasi kandang komunal. Penelitian ini dilakukan di Kelompok tani Gunung Harta dan Wonorejeki, Desa Tulungrejo menggunakan pendekatan kualitatif dengan desain studi kasus. Informan dalam penelitian ini adalah 1 orang yang ditetapkan secara purposive dan 4 orang snowball dengan Teknik pengumpulan data dilakukan dengan wawancara mendalam. Secara deskriptif, penelitian ini menghasilkan kesimpulan bahwa kehadiran inovasi kandang komunal menjadi sebuah inovasi yang dapat diterima secara kolektif oleh anggota kelompok tani. Sedangkan beberapa inovasi lain seperti mesin chopper, mesin pemerah susu, dan automatic water supply system tidak dapat diadopsi karena tergolong rumit dan tidak sesuai dengan kondisi lingkungan setempat.
The Meaning of Audience’s Reception on Da’wah Messages in the Gus Iqdam Youtube Channel: (A Reception Study On Majelis Taklim Al Muhsinin) kurniawan, jihan; Safitri, Reza
Sahafa Journal of Islamic Communication Vol. 7 No. 02 (2024): Sahafa Journal of Islamic Communication
Publisher : Universitas Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21111/sjic.v7i02.13284

Abstract

This study analyzes the audience's interpretation of da'wah messages on the Gus Iqdam YouTube channel, focusing on the Majelis Taklim Al Muhsinin congregation. Using a qualitative reception analysis method, the research reveals that audience interpretations vary, influenced by their social backgrounds and understanding of Islamic teachings. The findings show that YouTube as a platform significantly enhances the reach of da'wah, despite challenges in maintaining message relevance. This study emphasizes the importance of Da'wah Communication and Spiritual Communication approaches to explore the emotional and religious dimensions of Gus Iqdam's da'wah, which is adaptive and responsive in engaging diverse audiences in the digital era.
NAVIGATING PUBLIC RELATIONS IN LOCAL GOVERNMENT CONFLICTS:: A Study on The Entertainment Venue Closure in East Java Surya Darmawati; Maulina Pia Wulandari; Reza Safitri
SANGKéP: Jurnal Kajian Sosial Keagamaan Vol. 7 No. 3 (2024): Social Interaction, Education, and Tradition in Community Life
Publisher : Prodi Sosiologi Agama dan Asosiasi Sosiologi Agama Indonesia (ASAGI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20414/sangkep.v7i3.11587

Abstract

This study investigates the crucial function of the Public Relations (PR) Department of one of the Municipal administration offices in East Java in resolving issues between the administration and the public. The PR department is essential in overseeing the public perception by guaranteeing the clear and efficient distribution of information on government acts, policies, and initiatives.  The study is on the PR department's dual role as both an expert prescriber and a communication facilitato to improve government-public relations and mediate conflicts. The study employed a qualitative research methodology, which involved conducting interviews to investigate the role of the PR department. The findings suggest that the department is responsible for creating and executing communication strategies for the Mayor's office. They serve as a mediator between government officials and the public. The department also promotes the resolution of problems by working for the interests of both the government and the public, creating transparency and trust. Ultimately, the PR Department of the Municipal administration office is crucial for improving communication and maintaining constructive relations between the government and the public. The study suggests that enhancing strategic communication planning and implementing transparency measures would be beneficial in reinforcing public trust and promoting active participation.
THE RITUAL COMMUNICATION AS A MEDIUM FOR CULTURAL PRESERVATION AND COLLECTIVE IDENTITY: Study on Nyadran Sonoageng Tradition Siti Noer Tyas Tuti; Reza Safitri
SANGKéP: Jurnal Kajian Sosial Keagamaan Vol. 7 No. 3 (2024): Social Interaction, Education, and Tradition in Community Life
Publisher : Prodi Sosiologi Agama dan Asosiasi Sosiologi Agama Indonesia (ASAGI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20414/sangkep.v7i3.11820

Abstract

Nyadran Sonoageng tradition is a Javanese ritual that combines spiritual values, local culture and Islamic teachings. This study uses a sociocultural approach with communication ethnography method to explore the Nyadran tradition in maintaining social harmony in the midst of changing times. Based on James W. Carey's ritual communication perspective, this study found that symbolic elements such as jolen offerings, processions, and kenduri act as a medium of symbolic communication capable of transmitting collective values. Cross-generational participation in this ritual shows that Nyadran's role as a space to build communication harmony and maintain cultural continuity in a society. The transformation of implementation from simple or traditional to modernization in the implementation of Nyadran, such as the integration of entertainment elements and folk markets, shows the flexibility of tradition in responding to the dynamics of modernization.
Analysis of Disaster Risk Communication Strategies in the Disaster-Resilient Village Program in Sidomulyo Flower Tourism Village By BPBD Batu City Salsabila, Laluna; Pia Wulandari, Maulina; Safitri, Reza
Ranah Research : Journal of Multidisciplinary Research and Development Vol. 6 No. 5 (2024): Ranah Research : Journal Of Multidisciplinary Research and Development (Juli 20
Publisher : Dinasti Research

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38035/rrj.v6i5.951

Abstract

Disaster risk communication is an important thing to convey to the public so that they can recognize the potential and threats of disaster risk in the surrounding area. This research aims to analyze disaster risk communication strategies in the Disaster Resilient Village Program which has been carried out by BPBD Batu City in the Sidomulyo Flower Tourism Village. This research uses a qualitative approach with a case study method to explore the communication strategies implemented to increase awareness and disaster preparedness among the people of Sidomulyo Flower Tourism Village. Data collection was carried out through observation, in-depth interviews, and documentation studies. The results of the study show that the disaster risk communication strategy can be said to be effective because it is accurate and open. However, the BPBD Batu City is unable to reach all levels of society and has not established relationships with conventional media. This has been analyzed using five critical assumptions by Haddow and Haddow (2014), namely Customer Focus, Leadership Commitment, Inclusion of Communication Planning and Operations, Situational Awarness, and Media Partnership.
Co-Authors A.A. Ketut Agung Cahyawan W Airlangga, Muhammad Hafidz Daros Ansahnarmi, Annisa Arief, Muhammad Dimas Sulthan Astaningrum, Meita Dinar Atma Amanda Putri Avicenna, Fitria Azahar Kasim Bambang Dwi Prasetyo Budi Sawitri Chandra Sari, Rohmah Nia Darmawati, Surya Daros Airlangga, Muhammad Hafidz Darsono Wisadirana Edi Dwi Cahyono Eka Pradesti Eleonora Rumengan, Angelina Elsa Badriyya Erizal Zaini Febiola, Intri Fiaji, Noveria Anggraeni Firmannandya, Ade Fitri Avicenna Hanim, Faridha Hanindita Basmatulhana Hertanto, Dedy Iftita, Hasanatul Ihsan, Ikhwanul INDRAYANI INDRAYANI Ismi Aulil Wardani Jessica, Adhitya Kanto, Sanggar Kasim, Azahar Keppi Sukesi Keppi Sukesih Kliwon Hidayat kurniawan, jihan Kuswanto Kuswanto Lisda Veronika M.Pd S.T. S.Pd. I Gde Wawan Sudatha . Mashita Putri Hatama Maulina Pia Wulandari Monica Trivena Nainggolan Muhammad Hafidz Daros Airlangga Muhammad Syukri Nainggolan, Monica Trivena Nanang Krisdinanto Nelci Batlolona Ningtias, Iin Nisa Alfira Noor Aziah Abdullah Norhadi Norhadi Normahfuzah Ahmad Noveria Anggraeni Fiaji Noviadhista, Ulwan Fakhri Oktaviani, Fitri Hariana Patricia Baliana Da Costa Pramesthi, Hanum Kanthi Prasetyo, Agus Subhan Purwandi, Edeliya Relanika Putri Nila Rahmataini Putri Sadayi, Delila Putri, Atma Amanda Rachmat Kriyantono Rachmat Kriyantono Rilo Pambudi Riski Amalia Rizky Trisna Putri Rohmah Nia Chandra Sari Rois, Aulia Nur Rosaini, Henni Saafrida Said, Moch Fauzie Saleh, Ahmad Muwafik Salsabila, Laluna Sandis Wahyu Prasetiyo Sari, Rohmania Chandra Satriawan, Pravasta Wahyu Sinta Swastikawara Siti Noer Tyas Tuti Sujoko, Anang Sundoko Sundoko Surya Darmawati Susanto, Amin Heri Sylvatri, Hapsari Dian Trida, Mutiara Tristania Puspa Kintani Tyas Tuti, Siti Noer Ulwan Fakhri Noviadhista Uswatul Hasanah, Uswatul Utomo, Pradita Eko Prasetyo Wahyuni, Silvia Santi Warda Firdausi Karimah Wijanarko, Wisnu Wisnu Widjanarko Yandi Aulia Rahman Yayuk Yulianti Yeni Pramita Yuliza, Sukma