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A Review of Rational Pharmacotherapy in the Use of Antibiotics in Hospitals Haruna, Nadyah; Syakir, Darmawansyih; Nilawati, Andi
Sciences and Clinical Pharmacy Research Journal Vol. 2 No. 4 (2026): January
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/scpr.v2i4.5322

Abstract

This study aims to examine the rational pharmacotherapy of antibiotic use in hospital settings, focusing on patterns, determinants, and the role of antimicrobial stewardship (AMS) in optimizing therapeutic outcomes. Employing a qualitative descriptive design through a literature review, this research synthesized findings from scientific journals, official reports, and academic studies published between 2015 and 2025. Data collection involved systematic literature tracing and document analysis, while the data analysis process consisted of thematic identification, data reduction, categorization, and inductive interpretation. The results reveal that the rationality of antibiotic use in Indonesian hospitals remains low, ranging between 6.67% and 68.03%, with key issues involving inappropriate antibiotic selection, incorrect dosing, and inadequate therapy duration. Limited AMS implementation and minimal pharmacist involvement were identified as major contributing factors. Conversely, evidence demonstrates that multidisciplinary AMS programs, particularly those led by clinical pharmacists, significantly improve prescribing rationality, reduce resistance rates, and lower healthcare costs. The findings provide a comprehensive understanding of how institutional, behavioral, and policy factors influence rational antibiotic use, offering implications for both clinical practice and healthcare policy reform. In conclusion, the study underscores the need for sustained AMS integration, pharmacist empowerment, and standardized evaluation systems to strengthen rational pharmacotherapy and combat antimicrobial resistance.
HUBUNGAN STATUS GIZI, STATUS SOSIAL EKONOMI, DAN TINGKAT PENDIDIKAN DENGAN KEJADIAN ANEMIA PADA IBU HAMIL DI PUSKESMAS PAMPANG, KOTA MAKASSAR, TAHUN 2021–2022 Aisyah, Nur; Delima, Andi Alifia Ayu; Darmawansyih; Setiawati, Dewi; Alwi, Zulfahmi
Bina Generasi : Jurnal Kesehatan Vol 17 No 2 (2026): Bina Generasi : Jurnal Kesehatan
Publisher : LPPM STIKES BINA GENERASI POLEWALI MANDAR

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35907/bgjk.v17i2.517

Abstract

Introduction: Anemia in pregnancy is a condition in which pregnant women have hemoglobin (Hb) levels of <11 g/dL in the first and third trimesters, and <10.5 g/dL in the second trimester. Anemia during pregnancy can increase the risk of impaired fetal growth, higher perinatal mortality, preterm delivery, low birth weight, and decreased immunity in both mothers and infants. Objective: This study aimed to determine the relationship between nutritional status, socioeconomic status, and educational level and the incidence of anemia among pregnant women. Methods: This study employed a quantitative observational design with a cross-sectional approach and purposive sampling technique. A total of 173 pregnant women were selected from a population of 306. Secondary data were obtained from medical records. Results: The results showed a significant relationship between socioeconomic status and the incidence of anemia (p = 0.000). However, no significant relationship was found between nutritional status and the incidence of anemia (p = 0.193), nor between educational level and the incidence of anemia (p = 0.960). Conclusion: Socioeconomic status was significantly associated with anemia among pregnant women, while nutritional status and educational level were not.