Article Per Year (5 Year)
p-Index From 2021 - 2026
2.757
P-Index
This Author published in this journals
All Journal Jurnal Farmasi Andalas Jurnal Sains dan Teknologi Farmasi Indonesian Journal of Pharmaceutical Science and Technology Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Jurnal Sains dan Teknologi Pangan Jurnal Penelitian Farmasi Indonesia JURNAL PENDIDIKAN TAMBUSAI TEKNOLOGI PANGAN : Media Informasi dan Komunikasi Ilmiah Teknologi Pertanian Jurnal Katalisator JFIOnline Jurnal Ilmu Kefarmasian Indonesia Jurnal Health Sains Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Pharmaceutical Sciences and Research (PSR) SITAWA : Jurnal Farmasi Sains dan Obat Tradisional Jurnal Katalisator Jurnal Farmasi Indonesia Borneo Journal of Pharmacy Jurnal Bakti Nusantara Jurnal Kefarmasian Indonesia Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Melzi Octaviani
Sekolah Tinggi Ilmu Farmasi Riau
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

Published : 27 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 27 Documents
Search

 1   2   3 
POTENSI ANTIOKSIDAN DARI EKSTRAK KULIT BATANG Bauhinia semibifida Roxb Haiyul Fadhli; Ainun Nurain Nurdin; Melzi Octaviani
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (317.175 KB) | DOI: 10.36387/jiis.v4i1.257

Abstract

Telah dilakukan penelitian tentang uji aktivitas antioksidan ekstrak kulit batang pohon kupu-kupu (Bauhinia semibifida Roxb) dengan metode DPPH. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan dari ekstrak kulit batang pohon kupu-kupu (Bauhinia semibifida Roxb) terhadap radikal bebas. Pengujian aktivitas antioksidan menggunakan ekstrak n-heksana, etil asetat dan metanol dari kulit batang pohon kupu-kupu dan sebagai kontrol pembanding digunakan Vitamin C. Pengujian berdasarkan absorban DPPH terhadap ekstrak pada panjang gelombang 517 nm menggunakan microplate reader. Hasil penelitian menunjukkan bahwa ekstrak n-heksana kulit batang pohon kupu-kupu memiliki nilai IC50 137 µg/mL dengan nilai AAI <0,5 dan dikategorikan lemah, nilai IC50 ekstrak etil asetat 30,15 µg/mL dengan nilai AAI 1,32 dan dikategorikan kuat dan ekstrak metanol memiliki nilai IC50 sebesar 16 µg/mL dengan nilai AAI sebesar 2,5 yang dikategorikan sangat kuat. Hal itu menunjukkan bahwa ekstrak metanol kulit batang pohon kupu-kupu (Bauhinia semibifida Roxb) mempunyai aktivitas sebagai antioksidan yang sangat kuat dibandingkan dengan ekstrak lainnya.
Uji Aktivitas Antibakteri Ekstrak Etanol Daun dan Kulit Batang Sawo (Manilkara zapota (L.) Van Royen) Melzi Octaviani; Syafrina Syafrina
JURNAL ILMU KEFARMASIAN INDONESIA Vol 16 No 2 (2018): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (530.018 KB)

Abstract

Sapodilla (Manilkara zapota (L.) van Royen) is a plant that grows in a tropical climate, fruit all year round and the distribution is in the widespread in Indonesia. The contents of secondary metabolites in the leaves and the bark sapodilla are flavonoids, phenols and saponins are known to inhibit the growth of bacteria. The purpose of this research is to know the antibacterial activity of ethanol extract leaves and bark Sapodilla against Staphylococcus aureus and Propionibacterium acnes bacteria. The study was performed by disc diffusion method with the varyation concentrations of ethanol extract from the leaves and bark with a concentration of 50%, 25%, 12.5%, 6.25% and 3.125% respectively and the positive control is clindamycin and the negative control is DMSO . The diameter of the inhibition zone formed on the ethanol extract test of the leaves sapodilla against Staphylococcus aureus and Propionibacterium acnes at a concentration of 50% was 14.18 ± 0.13 mm and 15.33 ± 0.25 mm, respectively. While the diameter of the inhibition zone formed on the ethanol extract test of the bark against Staphylococcus aureus and Propionibacterium acnes at a concentration of 50% was 14.22±0.15 mm and 18.30±0.23 mm, respectively. The results of the data statistical analysis using oneway ANOVA, it shown a significant difference (p < 0.05) between the variation of the concentration of the extract. The test results shown that the antibacterial activity ethanol extract of the leaves and bark of Sapodilla had activity for inhibit the growth of Staphylococcus aureus and Propionibacterium acnes bacteria.
Sosialisasi Protokol Kesehatan dalam Mencegah Penularan Covid-19 di Kelurahan Bina Widya Kota Pekanbaru Rickha Octavia; Denni Anggraini; Adriani Susanty; Rahma Dona; Melzi Octaviani
Jurnal Health Sains Vol. 2 No. 7 (2021): Jurnal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v2i7.226

Abstract

COVID-19 cases in Riau Province are still showing a significant increase in numbers. This is due to the activities and mobility of the people of Riau Province who are very much outside the house. Problems in the community, among others, are still many who do not understand the prevention of COVID-19 transmission, including the importance of using masks when out of the house, the importance of personal hygiene, hand washing with soap, and pyshical distancing. The habit of implementing clean and healthy living behaviors is not easy, it requires understanding and motivation from individuals so that each individual is more disciplined in applying them. The purpose of this research is to increase people's knowledge about COVID-19 through leafleat media. The method used is qualitative method. Pretest the community to get an early overview of the understanding of health protocols in preventing the transmission of COVID-19. The results of the posttest questionnaire showed an increase in people's knowledge from not understanding to understanding and very understanding. This is because the measurement of knowledge is done by providing complete information about COVID-19 and its prevention through leaflet media that is very effective in improving one's knowledge. The conclusion of socialization research that has been conducted on November 29, 2020 at RW 09 RT 03 Bina Widya Village, Panam Pekanbaru Riau can be seen that there is an increase in public knowledge after this activity, thus adding to the public's insight on how to prevent the transmission of covid-19 and what foods can be consumed during the current pandemic in order to improve the immune system or immune system.
UJI AKTIVITAS ANTIBAKTERI SARI BUAH SAWO MANILA (Manilkara zapota (L.) van Royen) MUDA DAN MASAK TERHADAP BAKTERI Escherichia coli MELZI OCTAVIANI
Jurnal Penelitian Farmasi Indonesia Vol. 6 No. 1 (2017): jpfi
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (923.767 KB)

Abstract

The antibacterial activity of the Manila Fruit Juice (Manilkara zapota (L.) van Royen) Raw and Ripe againt Escherichia coli bacteria has been done with a solid dilution method. The purpose of this research is to know and compare the antibacterial activity of fruit juice sawo manila raw and ripe to inhibit the growth of Escherichia coli bacteria. The results of the Antibacterial Activity of Manila (Manilkara Zapota (L.) van Royen) Raw with a concentration of 100%, 80%, 60%, 40% and 20%, respectively, of 120 colonies/ml colonies, 154 colonies/ml, 179.33 colonies/ml, 195.33 colonies/ml and 196.67 colonies/ml with an average number of early colonies of bacteria 197.67 colonies/ml. The results shown that the concentration of 100% will be decreasing of 39% the colony. While, the antibacterial activity test’s results of manila fruit juice (Manilkara zapota (L.) van Royen) ripe with 100%, 80%, 60%, 40% and 20%, respectively, with the average number of colony 221.00 colonies/ml, 221.67 colonies/ml, 221.67 colonies/ml, 221.67 colonies/ml and 221.67 colonies/ml with an average number of early colonies of bacterial 222.00 colonies/ml. This indicated that the raw manila has antibacterial activity, while the manila ripe fruit juice shown no antibacterial activity against bacteria of Escherichia coli.
Uji Aktivitas Antimikroba Ekstrak Etanol Kulit Bawang Merah (Allium cepa L.) dengan Metode Difusi Cakram Octaviani, Melzi; Fadhli, Haiyul; Yuneistya, Erenda
Pharmaceutical Sciences and Research Vol. 6, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Shallots (Allium cepa L.) are generally used as cooking ingredients by the community. The part of the shallot widely used is only a part of the tuber, while the outer shell of the shallot is thrown away because it is only considered as wastes. Based on phytochemical screening results, extract of shallot peels contains phenolics, flavonoids, and terpenoids that can inhibit the growth of microorganisms. The purpose of this research is to know the antimicrobial activity of ethanol extract of shallot peels against Staphylococcus epidermidis and Staphylococcus aureus as Gram positive bacteria, Salmonella thypi and Eschericia coli as Gram negative bacteria and also antifungal activity against Trichophyton mentagrophytes. The study was performed using disc diffusion method with the variation of concentration of ethanol extract of the peels of 50%, 25%, 12.5%, 6.25%, 3.125% and 1.5625% w/v, respectively, the positive control of chloramphenicol for bacteria, the positive control of nystatin for fungi and the negative control of DMSO. The diameter of the inhibition zone formed on the activity assay of ethanol extract of the shallot peels against Staphylococcus epidermidis, Staphylococcus aureus, Salmonella thypi and Eschericia coli at the concentration of 50% was 11.75 mm, 16.03 mm, 9.42 mm and 7.77 mm, respectively. The inhibition zone formed on the activity assay of ethanol extract of the shallot peels against Trichophyton mentagrophytes at the concentration of 50% was 18.53 mm. As conclusion, ethanol extract of the shallot peels could inhibit the growth of Staphylococcus aureus, Staphylococcus epidermidis, Salmonella thypi, Escherichia coli and Trichophyton mentagrophytes.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAN FRAKSI BUAH Syzygium polyanthum Wigh Walp TERHADAP BAKTERI GRAM NEGATIF Melzi Octaviani; Rahima; Haiyul Fadhli
JURNAL KATALISATOR Vol. 6 No. 2 (2021): Jurnal Katalisator, Volume 6, No 2, 2021
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (605.821 KB) | DOI: 10.22216/katalisator.v6i2.395

Abstract

Tumbuhan salam (Syzygium polyanthum Wigh Walp) digunakan oleh masyarakat sebagai rempah dan bumbu penyedap rasa makanan. Selain itu, tumbuhan salam juga dapat digunakan untuk mengobati berbagai penyakit. Bagian tumbuhan salam yang dapat dimanfaatkan sebagai obat selain daun adalah bagian buah. Buah salam memiliki kandungan metabolit sekunder yaitu flavonoid, fenolik, saponin dan alkaloid yang diketahui mampu menghambat pertumbuhan bakteri. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri dari ekstrak etanol, fraksi n-heksana, fraksi etil asetat dan fraksi n-butanol buah salam terhadap bakteri Escherichia coli, Salmonella typhi dan Shigella dysenteriae dengan metode difusi cakram. Konsentrasi larutan uji yang digunakan 10%; 5%; 2,5%; 1,25%; 0,625%; 0,313%, 0,156% dan 0,078% b/v, serta kontrol positif ciprofloxacin 5 µg/disk dan kontrol negatif DMSO. Hasil uji aktivitas antibakteri dianalisis dengan menggunakan metode one way ANOVA dan uji Kruskall-Wallis. Didapatkan hasil (p<0,05) yang menunjukkan adanya perbedaan yang signifikan daya hambat yang diberikan antara kontrol dan seri konsentrasi. Hasil pengujian menunjukkan bahwa ekstrak dan fraksi buah salam memiliki aktivitas dalam menghambat pertumbuhan bakteri Escherichia coli, Salmonella typhi dan Shigella dysenteriae.
Uji Aktivitas Antijamur Sari Buah Belimbing Wuluh (Averrhoa bilimbi L.) Terhadap Jamur Candida albicans Melzi Octaviani; Fadila Fadila
Jurnal Katalisator Vol 3, No 2 (2018): KATALISATOR
Publisher : LLDIKTI Wilayah X

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (760.399 KB) | DOI: 10.22216/jk.v3i2.3309

Abstract

Uji aktivitas antijamur sari buah belimbing wuluh (Averrhoa bilimbi L.) terhadap jamur Candida albicans telah dilakukan dengan menggunakan metode dilusi padat. Penelitian ini bertujuan untuk mengetahui aktivitas antijamur sari buah belimbing wuluh (Averrhoa bilimbi L.) terhadap jamur Candida albicans. Hasil penelitian menunjukkan adanya penurunan  jumlah koloni jamur yang diperoleh pada konsentrasi 100%, 80%, 60%, 40% dan 20% berturut-turut dengan persentase 55%, 48%, 40%, 30% dan 0,16% terhadap pertumbuhan jamur uji. Hasil uji statistik one way ANOVA menunjukkan nilai p<0,05 (p=0,000) yang berarti seluruh konsentrasi menunjukkan adanya perbedaan signifikan antar seluruh kelompok perlakuan
Isolation of Endophytic Fungus from Leaves of Uncaria cordata (Lour.) Merr and Antibacterial Activity Against Propionibacterium acnes and Escherichia coli Melzi Octaviani; Winda Yusma Ameliah; Neni Frimayanti; Meiriza Djohari; Haiyul Fadhli
Borneo Journal of Pharmacy Vol. 5 No. 3 (2022): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v5i3.3692

Abstract

Uncaria cordata (Lour). Merr (akar kaik-kaik) is one of the medicinal plants used as antibacterial because it contains bioactive compounds that can inhibit the growth of microorganisms. The plant is one of the sources of endophyte fungal isolates that can be developed as an alternative to producing antibacterial compounds. This research aimed to isolate the endophytic fungus from the leaves of U. cordata and know the antibacterial activity against Propionibacterium acnes and Escherichia coli by disc diffusion. The Fungi that were isolated from the leaves of U. cordata were 17 isolates. The isolates were continued for antibacterial activity testing: IFED 1 (Nigrospora sp.), IFED 2 (Aspergillus sp.), IFED 3 (Fusarium sp.), and IFED 4, whose genus was unknown. The results obtained were fungal isolates IFED 1 to IFED 4 had activity in inhibiting the growth of P. acnes with moderate category (18.16 mm) and weak categories (6.21, 6.16, and 6.68 mm) and in E. coli with moderate category (14.56 mm) and weak categories (6.53, 6.71, and 7.23 mm). The results of One-Way ANOVA and Tukey's test showed a significant difference (p <0.05) between the diameter of the inhibition zone with the type of endophytic fungus supernatant isolated from the leaves of U. cordata. The best isolate of endophytic fungi inhibiting P. acnes and E. coli bacteria was IFED 1 (Nigrospora sp).
Analisis Kandungan Boraks Pada Gula Merah Yang Dijual Di Pasar Simpang Baru Panam Pekanbaru Susanti, Emma; ramadhan, alfitrah; Rahmah, musyirna; octaviani, melzi
SITAWA : Jurnal Farmasi Sains dan Obat Tradisional Vol. 3 No. 1 (2024): SITAWA : Jurnal Farmasi Sains dan Obat Tradisional
Publisher : LPPM Akademi Farmasi Imam Bonjol Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62018/sitawa.v3i1.73

Abstract

Gula merah merupakan salah satu bahan pangan yang dibuat dari olahan nira palma yaitu aren dan kelapa yang dibuat secara tradisional. Gula merah sering digunakan masyarakat indonesia sebagai bumbu masak serta pemanis makanan dan minuman karena memiliki aroma dan rasa yang khas. Pada proses pembuatan gula merah kini masih ditambahkan bahan tambahan pangan yang berbahaya sebagai pengawet dan pengeras. Belakangan ini marak isu mengenai penggunaan bahan tambahan kimia yang berbahaya dalam pembuatan gula merah, salah satunya adalah boraks. Boraks adalah salah satu senyawa yang dikenal masyarakat dengan asam borat yang dilarang penggunaanya sebagai bahan tambahan pangan, tetapi boraks masih ditambahkan sebagai pengawet pada gula merah yang bertujuan agar daya tahan lama dan sebagai pengeras pada gula merah. Tujuan penelitian ini adalah untuk mendeteksi ada atau tidaknya kandungan boraks pada gula merah dengan metode uji nyala api dan uji kertas tumerik (kurkumin). Pengambilan sampel dilakukan dengan metode purposive sampling. Hasil penelitian pada uji kualitatif sampel dengan metode nyala api dan kertas kurkumin menunjukan hasil tidak mengandung boraks yang ditandai dengan tidak terjadinya perubahan warna pada uji nyala api maupun uji kertas kurkumin.
Aktivitas Antibakteri dan Antijamur Fraksi Etil Asetat Kulit Buah Jeruk Manis (Citrus sinensis (L.) Osbeck) Octaviani, Melzi; Masnun, Lidiatil; Nasution, Musyirna Rahmah; Susanti, Emma; Utami, Rahayu; Furi, Mustika
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 15 No. 2 (2023): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v15i2.140

Abstract

The sweet orange (Citrus sinensis (L.) Osbeck) is a popular fruit. The part of the sweet orange that is consumed is only the fruit flesh, while the orange peel is only thrown away and not utilized. The sweet orange peel contains several secondary metabolites, namely alkaloids, flavonoids, tannins, phenols, saponins, and steroids, which have antimicrobial properties. This study aims to determine the effect of the concentration of the ethyl acetate fraction of sweet orange peel on antibacterial and antifungal activity in Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Salmonella typhi, and Candida albicans fungi using the disc diffusion method. The ethyl acetate fraction was prepared in several concentration series, namely 50%, 25%, 12.5%, 6.25%, 3.125%, and 1.5625% w/v. The results obtained showed that all concentrations of the ethyl acetate fraction series showed activity in inhibiting the growth of Salmonella typhi bacteria. Series concentrations of 3.125% to 50% have activity in inhibiting the growth of Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, and Candida albicans fungi. The results of the data analysis using statistical one-way ANOVA showed that the antibacterial and antifungal activities between the concentration series were significantly different (p<0.05) from the negative control.
Co-Authors Adriani Susanty agistia, nesa Agusri Boestari Ainun Alfatma Ainun Nurain Nurdin Akmal Djamaan Amanda, Denisya Anggraeni, Silvana Anggraini, Dhiva Annisa Annisa Armon Fernando Asiska Permata Dewi Della Ariska Deni Anggraini Denni Anggraini Eliza Fitri Emma Susanti Emma Susanti Emma Susanti Emrizal Erenda Yuneistya Erizal Zaini Ezuela, Deska Z Fadila Fadila Felycia Wardi Fina Aryani, Fina Furi, Mustika Ginta Rio Maranti Gressy Novita Haiyul Fadhli Husnawati Idzan, Nur Kamilah Jonang, Aqila Rifdah K, Della Yunita Sary. Kasnaidi, Ahmad Faisal Khairiah, Kinanti Bahy Masnun, Lidiatil Meiriza Djohari, Meiriza Miftahul Jannah Muharani, Siska Musyirna Rahmah Nst Musyirna Rahmah, Musyirna Nadilla Alfitri Nasution, Musyirna Rahmah Neni Frimayanti Nofri Hendri Sandi Nova Novita Novita Dewi Novita Sari Rahayu Utami Rahayu Utami Rahayu Utami Utami Rahima Rahma Dona ramadhan, alfitrah Repuja, Dira Rickha Octavia Rizki Annisa A Rizki Wulandari Rustini Rustini Rustini Rustini Safitri, Elsa Sari, Fatwa Aulia Sasnita, Nadya Ayu Septi Muharni Septiani Nindia Putri Sinata, Novia Suci Anggela Soraya Syafrina Syafrina utari, Mayang Wardi, Felycia Wildan Khairi Mukhtadi Winda Yusma Ameliah Wira Noviana Suhery Wiwin Suryani Yuneistya, Erenda