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All Journal VALENSI JURNAL KIMIA SAINS DAN APLIKASI REKAYASA Biology, Medicine, & Natural Product Chemistry EduChemia: Jurnal Kimia dan Pendidikan KOVALEN: Jurnal Riset Kimia IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) JC-T (Journal Cis-Trans): Jurnal Kimia dan Terapannya Science and Technology Indonesia AKSIOLOGIYA : Jurnal Pengabdian Kepada Masyarakat ALCHEMY Jurnal Penelitian Kimia JMM (Jurnal Masyarakat Mandiri) SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Chemistry Indonesian Journal of Chemical Research Jurnal Serambi Engineering Walisongo Journal of Chemistry Jurnal Kreativitas PKM Jurnal Farmasi Indonesia Jurnal Nuansa Akademik: Jurnal Pembangunan Masyarakat Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Pengabdian Pada Masyarakat Molekul: Jurnal Ilmiah Kimia Jurnal Pengabdian Masyarakat (Jupemas) Jurnal Kesehatan Bakti Tunas Husada Medical Sains : Jurnal Ilmiah Kefarmasian
Gatut Ari Wardani
Universitas Bakti Tunas Husada
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Physicochemical Characterization and Dissolution Enhancement of Mefenamic Acid–Isonicotinamide Crystalline Solid Dispersion Indra, Indra; Apriani, Nurul; Aprillia, Ade Yeni; Wulandari, Winda Trisna; Wardani, Gatut Ari; Gustaman, Firman
Biology, Medicine, & Natural Product Chemistry Vol 14, No 2 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.142.601-607

Abstract

Poor aqueous solubility limits the bioavailability of non-steroidal anti-inflammatory drugs like mefenamic acid. This study aims to improve the solubility and dissolution of mefenamic acid through crystalline solid dispersions using solvent evaporation and co-grinding techniques with selected co-formers. Solid dispersions were formulated at different drug-to-co-former ratios (1:1, 1:2, and 2:1) and characterized using differential scanning calorimetry, Fourier-transform infrared spectroscopy, and powder X-ray diffraction. DSC results revealed reduced crystallinity, indicated by the disappearance of melting peaks and the appearance of a single glass transition temperature. FTIR analysis confirmed hydrogen bonding between the drug and co-former, while PXRD patterns showed a loss of long-range order, supporting the formation of amorphous phases. Dissolution testing demonstrated a significant increase in drug release, particularly in the 1:2 formulation, which outperformed the pure drug and other ratios. These results confirm that the choice of preparation method and co-former ratio critically influence the performance of solid dispersions. This study provides valuable insights into the design of improved oral formulations for poorly soluble drugs, contributing to the advancement of pharmaceutical technology
Pelatihan Pembuatan “Smart Clean” sebagai Upaya Peninggatan Produktivitas Ibu PKK Desa Karangbenda Kabupaten Pangandaran Nurdianti, Lusi; Indra, Indra; Wulandari, Winda Trisna; Idacahyati, Keni; Setiawan, Fajar; Wardani, Gatut Ari; Aprillia, Ade Yeni; Gustaman, Firman
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 7, No 2 (2024): Volume 7 No 2 2024
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v7i2.12397

Abstract

ABSTRAK Pada saat ini, kesadaran tentang pentingnya penggunaan deterjen cair pakaian semakin meningkat. Kandungan surfaktan yang terkandung dalam detergen dapat menimbulkan dampak negatif bagi makhluk hidup dan lingkungan karena limbah yang tidak terurai dengan baik oleh mikroorganisme akan menjadi suatu permasalahan bagi lingkungan. Workshop ini bertujuan memberikan edukasi dan keterampilan kepada warga dalam memproduksi deterjen cair yang ramah lingkungan dan hemat biaya. Materi penyuluhan disampaikan dalam bentuk ceramah dan tanya jawab, dengan diharapkan peserta dapat memahami manfaat deterjen untuk kebersihan pakaian keluarga, mengenai deterjen pakaian yang ramah lingkungan, dan mampu melakukan sosialisasi serta mempraktekkan pembuatan deterjen pakaian sendiri. Berdasarkan hasil pengolahan statistik, terdapat peningkatan rata-rata nilai skor kuesioner peserta setelah mengikuti pelatihan dalam pembuatan deterjen cair pakaian. Hasil uji statistik menggunakan uji T berpasangan menunjukkan bahwa terdapat perbedaan rata-rata yang signifikan antara nilai rata-rata skor kuesioner peserta sebelum dan sesudah pelatihan. kegiatan workshop ini dapat memberikan manfaat yang baik bagi masyarakat dan lingkungan sekitar desa, seperti mengurangi biaya pengeluaran keluarga dan memberikan peluang berwirausaha penjualan deterjen cair pakaian. Kata Kunci: Deterjen, Ekonomis, Workshop, Ramah Lingkungan, Parigi  ABSTRACT At this time, awareness about the importance of using liquid laundry detergent is increasing. Because waste that does not properly decompose by microorganisms will become a problem for the environment, the surfactant content in detergents may have a negative effect on living things and the environment. This workshop aims to provide education and skills to residents in producing environmentally friendly and cost-effective liquid detergent. The education material is delivered in the form of lectures and questions and answers, with the hope that participants will be able to understand the benefits of detergent for cleaning family clothes, learn about environmentally friendly laundry detergent, and be able to socialize and practice making their own laundry detergent. Based on the results of statistical processing, there was an increase in the average score of participants' questionnaires after taking part in training in making liquid laundry detergent. The results of statistical tests using the paired T test showed that there was a significant average difference between the average scores of participant questionnaires before and after training. This workshop activity can provide good benefits for the community and environment around the village, such as reducing family expenses and providing entrepreneurial opportunities for selling liquid laundry detergent. Keywords: Detergent, Economical, Workshop, Environmentally Friendly, Parigi
Peningkatan Pengetahuan Masyarakat dalam Pemanfaatan dan Pemilihan Bahan Baku Obat Tradisional di Daerah Cikatomas Kabupaten Tasikmalaya Nurdianti, Lusi; Rahayuningsih, Nur; Wulandari, Winda Trisna; Aprillia, Ade Yeni; Idacahyati, Keni; Indra, Indra; Wardani, Gatut Ari; Setiawan, Fajar; Gustaman, Firman; Annissya, Widia Primi; Julyanti, Ai Rian
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 7, No 8 (2024): Volume 7 No 8 (2024)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v7i8.16066

Abstract

ABSTRAK Masyarakat daerah Cikatomas Kabupaten Tasikmalaya mata pencaharian utamanya adalah sebagai petani, sehingga tanaman tumbuh baik disana, pemanfaatan tanaman ini dapat dibuat untuk bahan baku jamu sehingga dapat memberdayakan dan mendorong masyarakat dalam upaya pengembangan kesehatan tradisional. Memberdayakan masyarakat dengan pengetahuan dan keterampilan dalam mengolah tanaman obat menjadi produk jamu yang bermanfaat bagi Kesehatan selain itu untuk meningkatkan kesadaran masyarakat tentang pentingnya memilih jamu yang aman dan memiliki izin edar dari BPOM serta mengembangkan potensi ekonomi lokal melalui usaha home industry berbasis produk jamu. Total peserta yang termasuk dalam kriteria inkulusi dalam kegiatan ini adalah 110 orang, penyuluhan yang dilakukan menggunakan metode presentasi dengan media spanduk, stiker, dan power point, selain itu dilakukan pretest dan post-test. Rata-rata pretest sebesar 58,41 dan post-test sebesar 92,95, berdasarkan hasil pengujian statistik nilai pretest dengan post-test memiliki perbedaan yang signifikan (p<0,05). Program penyuluhan pemanfaatan Bahan Baku Obat Tradisional dalam pembuatan sediaan jamu dan cerdas memilih obat tradisional di Kampung Parunggolong desa Lengkong Barang kecamatan Cikatomas Kabupaten Tasikmalaya mendapatkan respon yang positif dari masyarakat setempat. Kata Kunci: Obat Tradisional, Jamu, Cikatomas  ABSTRACT The people of the Cikatomas area in Tasikmalaya Regency primarily earn their livelihood as farmers. The plants grown there are well-suited for use as raw materials in herbal medicines. Utilizing these plants can empower and encourage the community in their efforts to develop traditional health practices. Empowering the community with knowledge and skills to process medicinal plants into beneficial herbal products not only increases public awareness about the importance of selecting herbal medicines that are safe and approved by BPOM but also helps develop local economic potential through home-based businesses centered around herbal medicine products. A total of 110 participants met the inclusion criteria for this activity. The counseling was conducted using presentations with banners, stickers, and PowerPoint. Additionally, a pretest and post-test were administered. The pretest average score was 58.41, while the post-test average was 92.95. Based on statistical testing, there is a significant difference between the pretest and post-test scores (p < 0.05). The outreach program focused on the use of traditional medicinal raw materials for making herbal medicine preparations and smart selection of traditional medicines in Parunggolong Village, Lengkong Barang Village, Cikatomas District, Tasikmalaya Regency, was well-received by the local community. Keywords: Traditional Medicine, Jammu, Cikatomas
Program Penyuluhan Registrasi Produk Kosmetik untuk Meningkatkan Kesadaran Remaja di SMK Farmasi Bina Putera Nusantar Tasikmalaya Nurdianti, Lusi; Rahayuningsih, Nur; Indra, Indra; Setiawan, Fajar; Gustaman, Firman; Wulandari, Winda Trisna; Wardani, Gatut Ari; Aprillia, Ade Yeni; Annissya, Widia Primi; Julyanti, Ai Rian
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 8, No 5 (2025): Volume 8 No 5 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v8i5.19960

Abstract

ABSTRAK Kosmetik telah menjadi kebutuhan sehari-hari, namun masih banyak produk yang tidak memenuhi standar keamanan dan regulasi. Banyak produk kosmetik illegal dan tidak terdaftar di Badan Pengawas Obat dan Makanan (BPOM), sehingga beresiko mengandung bahan berbahaya. Selain itu, kesadaran Masyarakat, terutama siswa/I sekolah kejuruan farmasi, tentang pentingnya kosmetik yang aman dan halal masih terbatas. Program pengabdian masyarakt ini bertujuan untuk meningkatkan pemahaman siswa/I SMK Farmasi Bina Putera Nusantara Tasikmalaya mengenai pentingnya penandaan dan regristrasi sediaan kosmetik yang baik dan halal, sehingga mereka dapat menjadi konsumen yang lebih cerdas dan kritis dalam memilih produk kosmetik. Kegiatan dilakukan dalam bentuk penyuluhan dengan metode presentasi, diskusi interaktif, serta pre-test dan post-test untuk mengukur pemahaman peserta. Media yang digunakan meliputi brosur, spanduk, dan presentasi menggunakan PowerPoint. Hasil evaluasi menunjukkan adanya peningkatan pemahaman siswa/I terhadap aspek legalitas dan keamanan kosmetik, ditunjukkan dengan peningkatan skor post-test dibandingkan pre-test. Siswa/I menjadi lebih memahami pentingnya regristrasi BPOM, penandaan kosmetik, seta konsep halal dalam produk kosmetik. Program penyuluhan ini efektif dalam meningkatkan kesadaran dan pengetahuan siswa/I mengenai kosmetik yang aman dan halal. Dengan edukasi yang tepat, generasi muda dapat menjadi konsumen yang lebih bijak dalam memilih dan menggunakan produk kosmetik yang terjamin kualitas serta keamanannya Kata Kunci: Penyuluhan, Kosmetik Halal, Regristrasi BPOM, Edukasi Konsumen, Keamanan Kosmetik  ABSTRACT Cosmetics have become an essential part of daily life. However, many products on the market do not meet safety and regulatory standards. The presence of illegal and unregistered cosmetics, which may contain harmful substances, remains a significant concern. Public awareness- particularly among vocational pharmacy students- is still lacking regarding the importance of safe and halal-certified cosmetics. This community engagement program aims to enhance students’ understanding of SMK Farmasi Bina Putera Nusantara Tasikmalaya regarding the importance of proper cosmetic labeling and registration, enabling them to become more informed and critical consumers. The program was conducted as an educational seminar using a presentation-based approach, interactive discussion, and pre-test and post-test assessment to evaluate participants’ comprehension. The materials were delivered through brochures, banners, and PowerPoint presentations. The evaluation results indicated a significant improvement in students’ knowledge of cosmetic legality and safety. Post-test scores demonstrated an increased understanding of BPOM registration, cosmetic labelling regulations, and halal certification requirements compared to pre-test results. The outreach program effectively raised students’ awareness and knowledge of safe and halal cosmetics. Proper education can empower younger generations to make informed choices when selecting and using cosmetics that comply with safety and regulatory standards. Keywords: Awareness Program, Halal Cosmetics, BPOM Registration, Consumer Education, Cosmetic Safety
Peningkatan pengetahuan masyarakat mengenai berbagai macam dan cara pemanfaatan tanaman obat keluarga (toga) di desa Linggalaksana Wardani, Gatut Ari; Auli, Tiffani Navisha; Syahrani, Ismi; Rachmadhiani, Ana Noviana; Assidik, Rizki Abdurochman; Mujahidah, Luthfi Najdah
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 8, No 3 (2024): September
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v8i3.25379

Abstract

Abstrak Indonesia merupakan salah satu negara dengan keanekaragaman hayati yang besar sehingga kaya akan berbagai tanaman yang memiliki potensi sebagai obat. Di Desa Linggalaksana, Kecamatan Cikatomas, Kabupaten Tasikmalaya, terdapat banyak tanaman yang berpotensi sebagai tanaman obat keluarga (TOGA) diantaranya binahong dan bunga telang, namun pemahaman masyarakat Desa Linggalaksana terkait pemanfaatan tanaman obat masih rendah. Penyuluhan ini bertujuan untuk meningkatkan pengetahuan masyarakat dan mendorong budidaya Tanaman Obat Keluarga (TOGA) di Desa Linggalaksana. Melalui penyuluhan, diskusi, dan tanya jawab, pengetahuan masyarakat Desa Linggalaksana meningkat secara signifikan, dari 5,38% menjadi 61,53%. Program ini diharapkan dapat mendorong penanaman TOGA lebih luas untuk meningkatkan kesadaran akan pentingnya tanaman obat keluarga. Kata kunci: tanaman; obat; herbal; keluarga; budidaya. Abstract Indonesia is one of the countries with great biodiversity, rich in various plants with medicinal potential. In Linggalaksana Village, Cikatomas District, Tasikmalaya Regency, there are many plants with the potential to be used as family medicinal plants (TOGA), including binahong and butterfly pea flowers. However, the understanding of the Linggalaksana Village community regarding the use of medicinal plants is still low. This outreach aims to increase the community's knowledge and encourage the cultivation of Family Medicinal Plants (TOGA) in Linggalaksana Village. Through outreach, discussions, and question-and-answer sessions, the knowledge of the Linggalaksana Village community increased significantly, from 5.38% to 61.53%. This program is expected to encourage wider TOGA planting to raise awareness of the importance of family medicinal plants. Keywords: plants; medicine; herbs; family; cultivation.
Co-Authors Ade Yeni Ade Yeni Aprilia Ade Yeni Apriliani Adinda Nur Octavia Agustina, Ariyanti Ahmad Tantowi Jaohari Alfanaar, Rokiy Andyny Dwinovia Rianty Anindita Tri Kusuma Pratita Anindita Tri Kusuma Pratita Anisa Pebiansyah Anisa Pebiansyah Annazalia Rustandi Putri Annissya, Widia Primi Apriani, Nurul Aprillia, Ade Yeni Ardiansyah, Dandi Ariyanti Agustina Assidik, Rizki Abdurochman Auli, Tiffani Navisha Ayu Erviena Bayu Tri Laksono Clarisa Kartika Putri Cucu Nurpatonah Dea Dara Pamungkas Denis Pajriati Diana Sri Zustika Diana Sri Zustika, Diana Sri Dichy Nuryadin Zain Ditha Rizqi Aulia Utami Dwi Puspa Syahirrah Ega Maulana Qudsi Estin Nofiyanti Estin Nofiyanti Estin Nofiyanti Estin Nofiyanti Eva Saefatuzzahro Fadilah, Refi Tazhqiyatul Fajar Setiawan Fajar Setiawan Fajar Setiawan FAJAR SETIAWAN Fajar Setiawan Fasya Ammatul Hawa Fathurohman, Mochamad Firma Gustaman Firman Gustaman Firman Gustaman Firman Gustaman Gustaman, Firman Hanna Nurul Husna Hanna Nurul Husna Hanna Nurul Husna Haura Aklina Elyasin Hendy Suhendy Heri Herdiana Hertikawati, Hesi Hesi Hertikawati Idacahyati, Keni Iis Sukmawati Indra Indra Indra Indra Indra, Indra Ira Rahmiyani Itmam Milataka Izfadllillah, Thesa Julyanti, Ai Rian Keni Ida Cahyani Keni Idacahyati Keni Idacahyati Keni Idacahyati Khoeruman Nur, Fauzan Lena Yulianti Lia Nuramalia Lilis Tuslinah Lilis Tuslinah Lilis tuslinah Lilis Tuslinah Lusi Nurdianti, Lusi Mellyanawaty, Melly Meri Meri Meri, Meri Micola, Muhammad Yolanda Mochamad Fathurohman Mochamad Fathurohman Mujahidah, Luthfi Najdah Nandhini Huda A Nisa Uswatun Khasanah Noer Laelly BTAG Nur Laili Dwi Hidayati Nur Rahayuningsih, Nur Nurcholis Salman Nurhidah, Mia Nurlita, Putri Octavani, Salsabila Hanifah Pebiansyah, Anisa Pikri Adit Praditya R Pratama, Azril Pratita, Anindita Tri Kusuma Rachmadhiani, Ana Noviana Rahma, Aisyah Alpiah Ratih Damayanti Richa Mardianingrum Rissa Putri Aulia Yulianto Rohganala, Vinka Fitria Rubiansyah Dio Lazuardi Ruswanto, Ruswanto Sagita Wulandari Salman, Nurcholis Salsabila Hanifah Octavani Salsabila Putri Awalia Rahmat Septian, Ade Dwi Shal Nurdinda Fauziah Sindi Lestari Siti Laila Abiya Sri Asih Sri Juari Santosa Sugiharti, Mulya Tri Syahirrah, Dwi Puspa Syahputra, Ricky Andi Syahrani, Ismi Taofik Hidayat Taufik Hidayat Taufik Hidayat Taufik Hidayat Taufik Hidayat Tiara Permata Sari Tita Nofianti, Tita Tresna Lestari, Tresna Vera Nurviana Wawan Rismawan Wawan rismawan Widdy Erlinasari Widya Puspitasari Winda Trisna Wulandari Winda Trisna Wulandari Winda Trisna Wulandari Winda Trisna Wulandari Winda Trisna Wulandari Winda Trisna Wulandari, Winda Trisna Zain, Dichy Nuryadin