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Analysis Related Factors with Behavior Use Method Contraception Long Term in Active KB Acceptors in the Family Planning Village Program in Sungai Penuh City Kiran Nandini; Vaulline Basyir; Firdawati Firdawati; Rima Semiarty; Syamel Muhammad; Ilmiawati Ilmiawati
Asian Journal of Healthcare Analytics Vol. 2 No. 2 (2023): November 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ajha.v2i2.8085

Abstract

Method Contraception Long Term (MKJP) is possible contraception used for a period long time, more than two years, effectively and efficiently For objective space birth is more than three years or end pregnancy in couples age already fertile no want to add child Again. Based on the data obtained found that active KB acceptors that is not 51.7 % used MKJP and only 48.3% used MKJP. Analysis is done in a way univariate, bivariate, and multivariate. Research results obtained that amount children (p-value 0.016), access service health (p-value 0.329), knowledge (p value 0.003), attitude (p value 0.014), support family (p value 0.048), and source information (p value 0.009). Based on the results Multivariate obtained the most dominant factor related to behavior use of MKJP, namely knowledge with the highest OR value was 1.897.
Relationship Between Risk Factors and The Incidence of Gestational Trophoblastic Neoplasia at RSUP Dr. M. Djamil Padang Year 2019-2021 Aldi Almujahid; Syamel Muhammad; Asterina
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 2 (2024)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.2.746-753.2024

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Background : Gestational Trophoblastic Neoplasia (GTN) is a tumor originating from cytotrophoblast and syncytotrophoblast that invades myometrium, damages surrounding tissue and blood vessels, and causing bleeding. Purpose : This study aims to determine the relationship between age, history of previous pregnancies, β-hCG levels, parity, and interval with last pregnancy on the incidence of GTN. Method : This research is an observational analytic study with a cross sectional research design. Univariate analysis was carried out which described the frequency distribution of variables and bivariate analysis with the chi square statistical test . Result : The results of this study showed that there was a significant relationship between age, history of previous pregnancies, β-hCG levels and parity) and the incidence of GTN, while the interval with the last pregnancy did not have a significant relationship with the incidence of GTN . Conclusion: It was concluded that age, history of previous pregnancy, β-hCG levels, and parity are risk factors for GTN.
Efficacy of EMCO Therapy on Serum β-hCG Levels in Case of Gestational Trophoblastic Neoplasm (GTN) at Dr. M. Djamil Hospital Padang 2019-2021 Attahhal Fikrian Syadiq Siregar; Syamel Muhammad; Elly Usman
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 2 (2024)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.2.754-762.2024

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Backgrounds: Etoposide, Methotrexate, Cyclophosphamide, and Vincristine (EMCO) Chemotherapy is used as an alternative therapy for patients with a diagnosis of Gestational Trophoblastic Neoplasm (GTN) at Dr. M. Djamil Hospital Padang because Actinomycin D has not been included in the National Formulation (FORNAS). Purpose: To determine the efficacy of EMCO therapy with limited Actinomycin D on serum β-hCG levels in Gestational Trophoblastic Neoplasm (GTN) cases at Dr. M. Djamil Padang Hospital in 2019-2021. Methods: The type of research used is numerical comparative analytics with a cross sectional approach. The number of samples was 17 GTN patients who had done EMCO chemotherapy and checked β-hCG levels before and after chemotherapy. The research was conducted from April to October 2022 at Dr. M. Djamil Hospital Padang. Data processing using total sampling technique and tested using Wilcoxon Test. Results: Most GTN patients were found to be <40 years old (64,7%), history of molar hydatidiform pregnancy (47,1%), last pregnancy interval <4 months (58,8%), β-hCG level before chemotherapy ranged from 104-105 mIU/mL (52,9%), tumor size >5 cm (58,8%), metastasis location in the internal genital tract (35,5%), and patients who did not have metastasis (52,9%). Conclusion: There was a significant decrease in β-hCG levels after chemotherapy using EMCO for three cycles in patients with a diagnosis of GTN.
PERITONEAL TUBERCULOSIS IN YOUNG AGE LADY MIMICKING GYNECOLOGY MALIGNANCY : A CASE REPORT Lusi Jelita Sari; Puja Agung Antonius; Syamel Muhammad
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.1.653-659.2024

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Background : Peritoneal tuberculosis is one of the most challenging forms of extrapulmonarytuberculosis to diagnose. Extrapulmonary TB is very difficult to diagnose because of its non-specific signs and symptoms, thus it sometimes leads to a diagnosis of gynaecologicalmalignancy such as advanced ovarian carcinoma.Case Report : A teenage girl, 12 years old, with a chief complaint of intermittent abdominalpain since the last 1 month. There was no history of an enlarged abdomen, fever and weightloss. Ultrasound examination revealed an irregular adnexal mass suggesting an ovarianmalignancy with other possibilities of an infectious process. Diagnostic laparoscopy andperitoneal biopsy were performed on the patient. Intraoperatively, multiple friable nodular-mylar peritoneal masses with abdominopelvic attachments and fibrin fibres and white vesicleswere found on the entire surface of the genitalia, peritoneum, and intestines. A mass biopsywas performed with histopathological results showing peritoneal tuberculosis. Currently, thepatient is undergoing anti-tuberculosis drugs (OAT) treatment.Discussion : The diagnosis of this disease is difficult to establish. Symptoms are highlyvariable and non-specific and can lead to the wrong tumour pathology. The clinicalcharacteristics are dominated by changes in general condition, abdominal pain and transitdisorders, as well as masses (20 to 25%). The gold standard for definitive PTB diagnosisremains laparoscopy with peritoneal biopsy and subsequent pathological or microbiologicalconfirmation. Yellow/white nodules in the peritoneum observed on the patient's laparoscopicimages are the hallmark of wet peritoneal TB. Omental thickening and abdominal cocoon withmatted small bowel are other classic laparoscopic findings for peritoneal TB.Conclusion : PTB has similar characteristics to peritoneal carcinoma, which makes diagnosisdifficult for clinicians. Early and correct diagnosis of PTB helps to initiate medical managementquickly and helps reduce morbidity and mortality.
Adjuvant Chemotherapy For FIGO Stage IIA2 Cervical Cancer : A Case Report Deni Heryanto; Syamel Muhammad; Puja Agung Antonius
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 2 (2024)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.2.792-800.2024

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Background : Cervical cancer ranked as the third most prevalent cancer among women. This case report is to examine the current status of adjuvant chemotherapy in the treatment of early-stage cervical cancer as documented in the literature. Currently, there is no established evidence supporting the therapeutic efficacy of adjuvant chemotherapy as a standalone treatment following radical hysterectomy surgery. Nevertheless, some literature recommend the use of adjuvant radiotherapy (AR), adjuvant chemotherapy (AC), or concomitant chemoradiotherapy (CCRT) as the standard adjuvant therapies for early-stage cervical cancer following radical hysterectomy with positive prognostic factor. Case report: A 53-year-old female was diagnosed with stage IIA2 in April 2021. The histology type was determined to be keratinized squamous cell carcinoma, moderately well differentiated. The patient underwent a radical hysterectomy, resulting in the acquisition of uterine and cervical tissue measuring 11x11×6 cm. The histology results revealed moderately to poorly differentiated keratinizing squamous cell carcinoma, with no invasion of the parametrium or pelvic lymph nodes with vaginal cutting margin is free of tumor growth, but lymph vascular space invasion was present. Subsequently, adjuvant chemotherapy was administered using carboplatin (AUC 5) and paclitaxel for a total of 6 cycles. After 2 years with follow-up with CT-Scan examination in April 2023 confirmed the absence of any residual mass. Conclusion: A radical hysterectomy combined with adjuvant chemotherapy has been shown to reduce the chance of recurrence or progressiveness of the disease, in which this patient did not experience a recurrence after two years of treatment  
Rapidly Growing Ovarian Granulosa Cell Tumor Following Complete Debulking for Suspected Ovarian Cancer with Histopathology Result of Benign Ovarian Cyst Muhammad, Syamel; Antonius, Puja Agung; Oktavian, Rizki; Savannah, Aisha
Molecular and Cellular Biomedical Sciences Vol 7, No 3 (2023)
Publisher : Cell and BioPharmaceutical Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21705/mcbs.v7i3.352

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Ovarian granulosa cell tumor (GCT) is a rare low-grade malignancy condition. One type of GCT is adult GCT (AGCT), which has the tendency for late recurrence. AGCT is clinically palpable and focally cystic and solid. In this case report, a condition of recurrent ovarian cancer after laparotomy debulking surgery was reported. A 57-year-old woman, who was diagnosed with AGCT, had a history of laparotomy debulking three months prior and complained of abdominal pain and enlargement, along with significant weight loss. Ultrasound examination revealed a solid cyst, raising suspicion of recurrent ovarian cancer. Laboratory results indicated elevated CA-125 levels. Histopathology results confirmed metastasis of AGCT, after the second laparotomy debulking was done. Recurrence of GCT is uncommon within three months of debulking. In this rare condition, we suggested a laparotomy debulking and adjuvant chemotherapy as a treatment. Effectiveness of treatment of recurrent disease is an independent risk factor to reduce the risk of another relapse and increase the survival rate.Keywords: granulosa cell tumor, ovarian cancer, debulking
Differences in Response to External Radiotherapy and Brachytheraphy as a Booster of Cervical Cancer Management Muhammad, Syamel; Wahyuni, Zulfia
Indonesian Journal of Obstetrics & Gynecology Science Volume 7 Nomor 1 Maret 2024
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v7i1.556

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Objective: to determine differences in the response to external box system radiotherapy with brachytherapy as a booster for cervical cancer management. Method: The research design was a case-control study. This study used a retrospective approach by observing patient medical records that were included in the study sample. This research was conducted at the Andalas University Hospital and Dr. M. Djamil Hospital Padang in April– May 2023. The number of samples was 40. Results: This study found that the radiotherapy treatment showed a Sum of Product Diameter (SPD) after the procedure decreased from 8.64 to 2.36. The brachytherapy treatment showed decreased results before and after SPD. Both treatments were equally effective in reducing SPD. Approximately 70% of patients with external box system radiotherapy had a complete response to therapy, and 80% of patients had a complete response in the brachytherapy group. Conclusion: There was no significant response to therapy between external box system radiotherapy and brachytherapy as a booster of stage IIB and IIIB cervical cancer management.Perbedaan Respon Radioterapi Eksternal Sistem Box dan Brakiterapi sebagai Booster Tatalaksana Kanker ServiksAbstrakTujuan: untuk mengetahui perbedaan respons radioterapi sistem kotak eksternal dengan brakiterapi sebagai penguat penatalaksanaan kanker serviks. Metode: Desain penelitian ini adalah studi kasus kontrol dan menggunakan pendekatan retrospektif dengan mengamati rekam medis pasien yang termasuk dalam sampel penelitian. Penelitian ini dilakukan di Rumah Sakit Universitas Andalas dan RSUP M. Djamil Padang pada bulan April-Mei 2023. Jumlah sampel sebanyak 40 pasien. Hasil: Penelitian ini menemukan bahwa pengobatan radioterapi menunjukkan penurunan Sum of Product Diameter (SPD) setelah prosedur dari 8,64 menjadi 2,36. Perawatan brakiterapi menunjukkan hasil penurunan sebelum dan sesudah SPD. Kedua perawatan tersebut sama-sama efektif dalam mengurangi SPD. Sekitar 70% pasien dengan radioterapi eksternal sistem box memiliki respon yang lengkap terhadap terapi dan 80% pasien memiliki respon yang lengkap pada kelompok bbrakiterapi. Kesimpulan: Tidak ada respon terapi yang signifikan antara radioterapi sistem kotak eksternal dan brakiterapi sebagai penguat penatalaksanaan kanker serviks stadium IIB dan IIIB.Kata kunci: kanker serviks, radioterapi eksternal, brakiterapi. 
Hubungan Nilai PCI Intraoperatif dengan Resektabilitas Kanker Ovarium di RSUP Dr. M. Djamil Padang Muhammad, Syamel; Fajriman, Fajriman
Indonesian Journal of Obstetrics & Gynecology Science Volume 6 Nomor 3 November 2023
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v6i3.532

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Tujuan: Ukuran luas massa sebelum operasi berperan dalam keberhasilan sitoreduksi komplit. Peritonial Carcinomatosis Index (PCI) adalah sistem yang paling umum digunakan untuk peritoneal carcinomatosis, dan indikator prognostik independen untuk hasil jangka panjang. Resektabilitas kanker ovarium ditandai dengan residu kanker berpengaruh terhadap prognosis. Penggunaan PCI pada kanker ovarium sebagai faktor prediktor resektabilitas akan meniadakan sebagian faktor perancu terkait tim bedah. Penelitian ini bertujuan mengetahui hubungan nilai PCI metastasis intraoperatif terhadap resektabilitas massa pada kanker ovarium stadium lanjut di RSUP Dr. M. Djamil Padang. Metode: Penelitian analitik observasional dengan desain cross sectional study. Kriteria inklusi berupa pasien kanker ovarium stadium lanjut 1C yang akan dilakukan operasi dan bersedia menandatangani informed consent sejak Oktober 2021. Hasil: Sebanyak 52.5% memiliki riwayat genetik, 72.5% berusia 40 – 70 tahun. Pasien rawatan kanker ovarium stadium lanjut di RSUP Dr. M. Djamil Padang sebanyak 95% IOTA SR malignant, sebanyak 100% memiliki nilai CA-125 > 35, 60% ukuran massa >1 cm. PCI tinggi (skor > 15-39) memiliki frekuensi lebih tinggi dibandingkan nilai PCI Rendah (62,5%). Persentase resektabel lebih tinggi pada nilai PCI rendah dibandingkan nilai PCI tinggi sebanyak 100% (<0.001). Kesimpulan: Terdapat hubungan signifikan antara nilai Peritoneal Carcinomatosis Index intraoperatif dan resektabilitas massa.Relationship between Intraoperative PCI Score with Resectability Ovarian Cancer at Dr. M. Djamil Hospital PadangAbstract Objective: Peritoneal Carcinomatosis Index (PCI) is the most commonly used peritoneal carcinomatosis system, also an independent prognostic indicator for long-term outcomes. The resectability of ovarian cancer characterized by cancer residue affects prognosis. The use of PCI in ovarian cancer as a predictor of resectability will negate some of the confounding factors related to the surgical team. This research to determine the relationship of intraoperative PCI value to mass resectability in advanced ovarian cancer at Dr. M. Djamil Padang Hospital. Method: observational analytic research with cross-sectional study design. The inclusion criteria were advanced stage 1C ovarian cancer patients who will undergo surgery and are willing to sign informed consent since October 2021. Results: 52.5% have a genetic history, 72.5% are 40 – 70 years. For patients with advanced ovarian cancer treatment at Dr. M. Djamil Padang Hospital 95% of malignant SR IOTA,  100% have CA-125 values> 35, 60% of mass size >1 cm. High PCI (score > 15-39) has a higher frequency than a Low PCI value (62.5%). The percentage of resectable is higher in low PCI scores than in high PCI scores, about 100% (<0.001). Conclusion: There is a significant relationship between intraoperative peritoneal carcinomatosis index and mass resectability.Key word: Peritonial Carcinomatosis Index, resectability, ovarian cancer
Hubungan paritas, tingkat pengetahuan ibu, dan teknik menyusui dengan kejadian puting lecet pada ibu menyusui di wilayah kerja Puskesmas Dadok Tunggul Hitam Kota Padang Ridwan, Laila Hijradesy; Muhammad, Syamel; Halida, Erda Mutiara; Firdawati, Firdawati
Jurnal Riset Kebidanan Indonesia Vol 8, No 2 (2024): Desember
Publisher : AIPKEMA (Asosiasi Institusi Pendidikan Kebidanan Muhammadiyah-'Aisyiyah Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32536/jrki.v8i2.291

Abstract

Latar belakang: Menyusui dapat melindungi bayi dari berbagai penyakit dan menciptakan generasi emas di masa mendatang melalui program ASI eksklusif. Akan tetapi, capaian pemberian ASI eksklusif di Puskesmas Dadok Tunggul Hitam merupakan capaian paling rendah di Kota Padang sebesar 40,1%. Salah satu penyebabnya adalah kejadian puting lecet. Tujuan penelitian: mengetahui hubungan paritas, pengetahuan, dan teknik menyusui dengan kejadian puting lecet di Puskesmas Dadok Tunggul Hitam Kota Padang. Metode: Penelitian analitik dengan metode cross-sectional di Puskesmas Dadok Tunggul Hitam pada bulan September 2023. Sampel dalam penelitian ini adalah ibu yang menyusui bayi dengan usia 0-6 bulan (Maret 2023-Agustus 2023) sebanyak 73 responden. Sampel diambil dengan teknik Simple Random Sampling. Analisis data secara univariat, bivariat menggunakan Chi-square, dan multivariat menggunakan analisis regresi logistik dan koefisien determinan. Hasil: Hasil uji bivariat mendapatkan 49,3% responden dengan paritas multipara (p=0,005), 69,9% responden memiliki pengetahuan baik (p=0,000), dan 90,4% responden mengetahui teknik menyusui yang benar (p=0,001). Hasil multivariat menunjukkan variabel tingkat pengetahuan memiliki p-value 0,001 dan memiliki nilai OR paling besar yaitu 6,553. Maka dapat disimpulkan bahwa variabel pengetahuan ibu merupakan variabel yang lebih dominan atau berpengaruh terhadap kejadian puting lecet. Simpulan: Ada hubungan antara paritas, tingkat pengetahuan ibu, dan teknik menyusui dengan kejadian puting lecet.
Uji Daya Hambat Filtrat Lactobacillus gasseri Terhadap Pertumbuhan Staphylococcus aureus yang Diisolasi dari Genitalia Wanita Husna, Annisa Tamara; Suharti, Netti; Akhyar, Gardenia; Putra, Andani Eka; Muhammad, Syamel; Ilmiawati, Cimi
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 4 (2024): Desember 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i4.1329

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Latar Belakang: Lactobacillus gasseri merupakan salah satu jenis bakteri terbanyak ditemukan pada vagina wanita yang dapat menghasilkan bakteriosin sebagai senyawa antibakteri. Bakteriosin dijadikan alternatif melawan bakteri yang resisten terhadap antibiotik, salah satunya Staphylococcus aureus. Selain itu, Staphylococcus aureus merupakan salah satu penyebab vaginitis aerobik yang diteliti dapat membahayakan kehamilan hingga persalinan. Objektif: Tujuan penelitian ini adalah mengetahui kadar hambat minimal (KHM) dan kadar bunuh minimal (KBM) sebagai indikator untuk melihat kemampuan filtrat bakteriosin Lactobacillus gasseri dalam menghambat pertumbuhan Staphylococcus aureus. Metode: Penelitian ini dilakukan pada bulan Mei-November 2023 di Laboratorium Mikrobiologi Fakultas Kedokteran Universitas Andalas dan Laboratorium Pusat Diagnostik dan Riset Penyakit Infeksi Fakultas Kedokteran Unand. Sampel penelitian ini adalah Staphylococcus aureus yang diperoleh dari swab vagina yang dikultur di Laboratorium Mikrobiologi Fakultas Kedokteran Universitas Andalas. Penelitian dilakukan dengan teknik dilusi dan Real Time PCR dengan desain penelitian rancangan acak lengkap. Hasil: Nilai KHM dari filtrat bakteriosin Lactobacillus gasseri terhadap Staphylococcus aureus diperoleh pada konsentrasi >20% dan <40%, sedangkan nilai kadar bunuh minimal (KBM) diperoleh pada konsentrasi 40%. Kesimpulan: Filtrat bakteriosin Lactobacillus gasseri memiliki efek bakteriostatik dan bakterisidal terhadap pertumbuhan Staphylococcus aureus yang dipengaruhi oleh konsentrasi dari filtrat bakteriosin Lactobacillus gasseri.
Co-Authors Afriyeni Sri Rahmi Aisha Savannah Aldi Almujahid Almujahid, Aldi Amel Yanis Andani Eka Putra Antonius, Puja Agung Anugrah, Mutia Paramadita Ardian Riza Asterina Asterina Aswiyanti Asri Aswiyanti Asri Attahhal Fikrian Syadiq Siregar Ayu Anissa Bahri Bobby Indra Utama Caesar Muhammad Wijaya Cimi Ilmiawati, Cimi Citra Ayu Fitrisia Daan Khambri Delmi Sulatri Delsy Nurrizma Deni Heryanto Deni Heryanto, Deni Deo Cerlova Milano Dewi, Madona Utami Dewi, Madona Utami Dodi Suardi Elly Usman Elly Usman Fajriman, Fajriman Fathiyyatul Khaira Firdawati Firdawati Firdawati Firdawati, Firdawati Gardenia Akhyar Hafni Bachtiar Halida, Erda Mutiara Haris Pemuda Hasmiwati Hendra Herizal Hendra Permana Henny Mulyani Husna Yetti Husna, Annisa Tamara Ilmiawati Ilmiawati, Ilmiawati Karmia, Hudila Rifa Khatimah, Gistin Husnul Kiran Nandini Kiran Nandini Lucy Patmasari Lusi Jelita Sari Madona Utami Dewi MARINGAN DIAPARI LUMBAN TOBING Mitra Virgusrudhina Muhammad Zaldy Rasyid Putra Murizal, Thanya Amoret Alya Mustika Sari Muthia Kamelia Nabilla Mahyenda Nadhifa Naura Reyani Netti Suharti, Netti Nindya Rahmadita Nindya Rahmadita Nisa Ayu Farma Nurhalimah Juneldi Pamelia Mayorita Permata Rachim, Dyan Puja Agung Antonius Puji Anugrah Restu Susanti Reyhan Julio Ridwan, Laila Hijradesy Rijalul Abrar Rima Semiarty Rosfita Rasyid Rozi Sastra Purna Rudy Setiawan, Muhammad Santy Saberko Savannah, Aisha Selfi Renita Rusjdi Siregar, Attahhal Fikrian Syadiq Sugeng, Santoso Sukri Rahman Susan Meuthia Timmy Larasati Tofrizal Vaulline Basyir Vaulline Basyir Wahyuni, Zulfia Wijaya, Caesar Muhammad Yenita Afriyeni Yessy Setiawati Yusrawati Yusrawati