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All Journal Jurnal Kesehatan Andalas Molecular and Cellular Biomedical Sciences (MCBS) Syntax Literate: Jurnal Ilmiah Indonesia Indonesian Journal of Obstetrics & Gynecology Science Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Journal of Midwifery Majalah Kedokteran Andalas Bioscientia Medicina : Journal of Biomedicine and Translational Research Health and Medical Journal Contagion: Scientific Periodical Journal of Public Health and Coastal Health Andalas obstetrics and gynecology journal Jurnal Kebidanan Indonesia Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Ilmu Kesehatan Indonesia (JIKSI) Jurnal Riset Kebidanan Indonesia Asian Journal of Healthcare Analytics Indonesian Journal of Advanced Research (IJAR) Jurnal Riset Ilmiah
Syamel Muhammad
Universitas Andalas, Padang
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Carcinoma Endometrioid Ovary pada Struma Ovarii Muhammad, Syamel; Antonius, Puja Agung; Meuthia, Susan; Savannah, Aisha
Health and Medical Journal Vol 5, No 3 (2023): HEME September 2023
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v5i3.1361

Abstract

Kanker ovarium merupakan penyebab utama kematian pada wanita yang didiagnosis sebagai kanker ginekologi. Tingginya angka kematian akibat kanker ovarium karena mayoritas kasus bersifat asimptomatik dan skrining yang dilakukan untuk menegakkan diagnosis masih kurang. Hal ini menyebabkan kanker ovarium dikenal sebagai silent killer. Etiologi spesifik kanker ovarium hingga belum diketahui dengan pasti, namun teradapat beberapa faktor risiko yang berperan terhadap terjadinya kanker ovarium. Faktor risiko genetik diduga berkaitan erat dengan kejadian kanker ovarium, diantaranya mutasi pada gen TP53, BRCA1 dan BRCA2.  Diagnosis kanker ovarium sulit dilakukan pada stadium dini karena tidak adanya gejala spesifik.  Untuk menegakkan diagnosis kanker ovarium dibutuhkan anamnesis, pemeriksaan fisik dan pemeriksaan penunjang seperti CT scan, USG, pemeriksaan tumor marker dan biopsi. Hingga saat ini, pembedahan masih menjadi penatalaksanaan utama bagi kanker ovarium. Pemeriksaan histopatologi juga perlu dilakukan untuk menentukan keganasan, jenis kanker, dan penentuan staging. Kemoterapi adjuvan diberikan pada pasien setelah pembedahan, kecuali jika penyakit hanya terbatas pada ovarium dan  pada kanker yang tidak bisa dioperasi. Prognosis kanker ovarium bergantung dari jenis kanker, stadium  dan komplikasi yang terjadi. Pada jurnal ini dilaporkan kasus seorang pasien perempuan, berusia 59 tahun dengan carcinoma endometrioid ovary pada struma ovarii.
Hubungan Kualitas Antenatal Care dengan Kejadian Bayi Berat Lahir Rendah di Puskesmas Andalas Tahun 2021 Najla, Azarine Shidqi; Afdal, Afdal; Muhammad, Syamel
Jurnal Ilmu Kesehatan Indonesia Vol. 4 No. 4 (2023): Desember 2023
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v4i4.1175

Abstract

Latar Belakang: Bayi berat lahir rendah adalah suatu kondisi ketika bayi lahir dengan berat di bawah 2.500 gram tanpa menghitung usia gestasi. Banyak faktor yang dapat menyebabkan bayi berat lahir rendah, salah satunya adalah kualitas antenatal care ibu selama kehamilan. Objektif: Tujuan penelitian ini adalah untuk mengetahui hubungan kejadian bayi berat lahir rendah dengan kualitas antenatal care di wilayah kerja Puskesmas Andalas tahun 2021. Metode: Penelitian ini merupakan penelitian analitik observasional dengan desain cross sectional pada 43 ibu yang melahirkan tahun 2021 di wilayah kerja Puskesmas Andalas yang dilaksanakan pada bulan Juni 2023. Subjek pada penelitian ini dipilih dengan teknik purposive sampling. Pengumpulan data dilakukan dengan melakukan wawancara menggunakan kuesioner antenatal care dan observasi buku KIA. Data dianalisis menggunakan uji chi-square. Hasil: Hasil penelitian menunjukkan frekuensi bayi berat lahir rendah sebesar 16,3%, dan pada umumnya ibu mendapatkan kualitas antenatal careyang baik. Analisis bivariat menunjukkan tidak terdapat hubungan antara kejadian bayi berat lahir rendah dengan kualitas antenatal care di wilayah kerja Puskesmas Andalas tahun 2021. Kesimpulan: Tidak ada hubungan antara kualitas antenatal care dengan berat lahir rendah, sehingga perlu diperhatikan faktor penyebab berat lahir rendah lainnya agar kejadian bayi berat lahir rendah dapat dicegah. Kata Kunci: berat lahir rendah, antenatal care, ibu
Migraine And Pregnancy: What Should We Know Susanti, Restu; Muhammad, Syamel
Andalas Obstetrics And Gynecology Journal Vol. 4 No. 2 (2020)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.4.2.251-260.2020

Abstract

Migraine is a common headache characterized by unilateral throbbing-like headache and pulsating in nature and sometimes associated with aura. Migraine is a disabling disorder that among adults is more prevalent among women than men. It is primary headache that is often found in pregnancy. Migraine is a common disorder in women of childbearing age, and usually requires pharmacological treatment. Migraine can be considered an important risk factor for hypertensive and vascular diseases during pregnancy. Migraine therapy in pregnancy is very challenging, it must taken into a consideration about the health of the mother and fetus.  Several effective antimigraine medications are reasonably safe for use by pregnant and breastfeeding women. Prophylactic theraphy should be given to patient with recurrent migraine attacks in pregnancy. Nonpharmacological strategies are always first-line treatment options for mild migraine, and should also be used complementarily whenever pharmacological treatment is required. Women with migraine should be offered periconceptional counselling to promote a safe and healthy pregnancy. Keywords: migraine; pregnancy; therapy
Correlation of Tumor Vascularization Using Spectral Pulse Wave Doppler with Neoadjuvant Chemotherapy Response in IB2 and IIA2 stages of Cervical Cancer Muhammad, Syamel; Rahmadita, Nindya
Andalas Obstetrics And Gynecology Journal Vol. 4 No. 2 (2020)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.4.2.145-154.2020

Abstract

Cervical cancer is an abnormal growth or cell changes in the cervical wall, which is the 4th rank in the most common cancer among female and the 2nd most common cancer in female aged fifteen until fourty four years old worldwide. Neovascularization becomes an important step in determining the onset and progressive cancer. Neoadjuvant chemotherapy has been evaluated as a treatment strategy in the stages IB2 and IIA2. The use of chemotherapy drug becomes more effective in adjacent and regular vascularization, and it allows the blood flow to the organs more quickly. This study aims to determine the correlation of tumor vascularization using Spectral Pulse Wave Doppler with neoadjuvant chemotherapy response in IB2 and IIA2 stages of cervical cancer. This research is a cohort analytic study which involves thirty six of patient in IB2 and IIA2 stages. The sampling is selected by using consecutive sampling technique. The data includes the result of ultrasound examination and were analyzed by using the Chi-square test. The results of the research on good and poor tumor vascularization had a good response to thirty of patient (83.3%) who were given neoadjuvant chemotherapy. There was no significant effect between tumor vascularization using Spectral Pulse Wave Doppler to the responses of neoadjuvant chemotherapy in IB2 and IIA2 stages of cervical cancer.Keywords: tumor vascularization using Spectral Pulse Wave Doppler, responses of neoadjuvant chemotherapy, IB2 and IIA2 stages of cervical cancer
Selecting Hormonal Contraceptives in Women Taking Antiepileptic Drugs : Review of Literature and Practical Recommendations Permana, Hendra; Susanti, Restu; Muhammad, Syamel
Andalas Obstetrics And Gynecology Journal Vol. 4 No. 2 (2020)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.4.2.231-240.2020

Abstract

Contraception is a very important issue in women with epilepsy, since very broad questions taken in applying it to prevent unplanned pregnancy. The choice of contraceptive methods must be related to how the mechanism of action of antiepileptic drugs (AEDs), the contraceptive itself, and both interactions. Hormonal contraception can induce metabolism of AEDs and lead to increasing of seizure frequency, and in the other hand AEDs may decrease the blood levels of hormonal contraception. Therefore, physician must consider the type of contraception being used before prescribing AEDs. Additionally, they should emphasize the interaction between them in counseling, to assure that women with epilepsy have time to decide which type will be best use for them. This challenging matter needs better recommendation for practice, both neurologist and gynecologist.Keywords: antiepileptic drug, contraception, women with epilepsy
How far is Covid-19 Pandemic Situation Influence Surgical Treatment in Gynecology Cancer? : Comprehensive Review for Indonesian Muhammad, Syamel; Susanti, Restu
Andalas Obstetrics And Gynecology Journal Vol. 4 No. 2 (2020)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.4.2.203-217.2020

Abstract

Corona virus disease 2019 (COVID-19) was declared as global pandemic and caused devastating crisis in society. Despite of the growing pandemic, high quality medical services toward gynaecologic oncology patients must continue without overlooking the safety of medical staffs. Reducing risk is crucial and achieved by limiting high risk situations. The decision to perform or postpone surgery should be made based on the type and stage of the disease, medical condition of the patient, area census of COVID-19 cases, COVID-associated risks, and available logistic support including adjuvant treatment services. There are several recommendation for gynaecology cancer treatment published by several countries. However, those guidelines cannot be applied to every country across the globe because of the different situations of COVID-19 therefore we proposed guidelines for Indonesia. Surgical management for confiermed COVID-19 case should be postponed for at least 15 days for nonemergency cases. Surgery must be performed immediately for emergency cases such as Haemorrhage with unstable vital status refractory to transfusion, viscus perforation, signs of bowel obstruction refractory to conservative treatment, closed loop bowel or large bowel obstruction, hydatiform mole for live saving procedure.  Keywords: COVID-19, gynaecology cancer, surgical management
Premature Ovarian Failure and Epilepsy Permana, Hendra; Rahmi, Afriyeni Sri; Muhammad, Syamel
Andalas Obstetrics And Gynecology Journal Vol. 5 No. 1 (2021)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.1.1-8.2021

Abstract

Premature ovarian failure (POF) or premature menopause refers to development of amenorrhoea due to cessation of ovarian function before the age of 40 years. The diagnosis is based on elevated FSH levels in menopausal range (usually above 40 IU/l) detected on at least two occasions a few weeks apart. The term “epilepsy” defines a group of disorders characterized by an enduring predisposition of the brain to produce seizures. The hypothalamic-pituitary-ovarian axis regulation is affected by the abnormal neurophysiology of seizures, and the hypothalamic-pituitary-ovarian associated hormones are affected by medications used to treat seizures in women with epilepsy. Ictal and interictal discharges can disrupt the normal activity of brain structures, including the limbic system, amygdala, hypothalamus, and pituitary gland. Management of epilepsy in women requires not only knowledge of epilepsy, but also recognition of the various roles and priorities women have in their lives (education, career development, child rearing, the role as carer within the extended family), and attention to gender-specific issues and their impact on patients’ wellbeing throughout life.Keywords: premature ovarian failure (POF), epilepsy
Menstrual Migraine : How Hormones Impact Migraine Susanti, Restu; Muhammad, Syamel
Andalas Obstetrics And Gynecology Journal Vol. 5 No. 1 (2021)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.1.9-17.2021

Abstract

Menstrual Migraine is divided into 2 subtypes: Menstrually Related Migraine (MRM) and Pure Menstrual Migraines (PMM). In PMM symptoms do not occur outside the menstrual cycle while MRM, symptoms can occur at other times apart from the menstrual cycle. The occurrence of menstrual migraines is related to the female hormones cycle in the form of the decrease in estrogen levels which usually occurs a week before the onset of menstruation. The mechanism is unclear, but it is thought that a decrease in estrogen levels can trigger decrease in serotonin levels, causing cranial vasodilation and sensitization of the trigeminal nerve.  Keywords: menstrual migraine, hormones
Primary Fallopian Tube Carcinoma : A Case Report Abrar, Rijalul; Muhammad, Syamel
Andalas Obstetrics And Gynecology Journal Vol. 5 No. 1 (2021)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.1.130-138.2021

Abstract

Objective: To report the case of primary fallopian tube carcinoma metastatic to cervix and omentum, but not infiltrate the ovariumMethod: Case Report Case: A 40 years old woman presented with gradual onset pain and swelling of the abdomen. The patient was diagnosed with suspected ovarian carcinoma. After examination, the patient prepared for laparotomy; salpingo-oophorectomy, omentectomy, mass resection from pelvic and rectum  Result: The hystological examination result was high grade serous carcinoma from the fallopian tube metastasis to cavum douglas and omentum. This case is a rare case because the tubal carcinoma was metastasis to cavum douglas and omentum without infiltrate the ovarium.Discussion: Primary carcinoma of the fallopian tube is rare and accounts for about 0.14-1.8% of all gynecological malignancies. Clinically the diagnose of tubal carcinoma very similar to ovarian cancer, the diagnose can not distinguished pre operative. The new staging of FIGO may be reference for diagnostic and treatment of the desease. Thorough staging laparotomy is an important part of early management and systemic treatment. Keywords: tubal carcinoma, PFTC, metastasis, high grade serous carcinoma
Ovarian Clear Cell Carcinoma which Detected in Ascitic Fluid Smear Kamelia, Muthia; Asri, Aswiyanti; Muhammad, Syamel
Andalas Obstetrics And Gynecology Journal Vol. 5 No. 2 (2021)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.2.269-277.2021

Abstract

Objective: To report the case of ovarian clear cell carcinoma with involvement of both ovaries and metastatic to ascitic fluid and the label mass in the bladderMethod: Case Report  Case: A 51 years old female presented with enlarging abdominal with gradual pain. The result of transabdominal sonography were multiple cysts with solid mass, suspected solid cystic ovarian neoplasm and ascites. The patient prepared for laparotomy; optimal debulking surgery, mass resection from bladder. Cytology examination was performed from ascitic fluid and it was confirmed by histopathology examination.Result: Microscopic features on cytology examination of ascitic fluid smear was suggest carcinoma. Histological examination was confirmed the diagnosis and the result was ovarian clear cell carcinoma. Discussion: Ovarian clear cell carcinoma is a rare subtype of epithelial ovarian cancer and comprises about 5-10% of ovarian carcinomas. Clear cell carcinoma tends to occur in the fifth to seventh decades. Cytology examination showed the cellular smear consists of groups of epithelial cells with large nucleus, hyperchromatic, pale-staining, vacuolated cytoplasm. There is also eosinophilic, extracellular substance. The presence of a tumor in ascitic fluid and the label mass in the bladder can categorize become IIB. This determined based on the FIGO’s ovarian tumor staging system.Keywords: ovarian clear cell carcinoma; ascitic fluid.
Co-Authors Abrar, Rijalul Afdal Afdal, Afdal Afriyeni Sri Rahmi Aldi Almujahid Almujahid, Aldi Amel Yanis Andani Eka Putra Antonius, Puja Agung Anugrah, Mutia Paramadita Ardian Riza Ariani, Novita Asterina Asterina Aswiyanti Asri Aswiyanti Asri Attahhal Fikrian Syadiq Siregar Ayu Anissa Bahri Ayu Anissa Bahri, Ayu Anissa Basyir, Vaulline Bobby Indra Utama Caesar Muhammad Wijaya Cimi Ilmiawati, Cimi Citra Ayu Fitrisia Daan Khambri Delmi Sulatri Delsy Nurrizma Deni Heryanto Deni Heryanto, Deni Deo Cerlova Milano Dewi, Madona Utami Dewi, Madona Utami Dodi Suardi Eka Fithra Elfi, Eka Fithra Elly Usman Elly Usman Erlina Rustam Fajriman, Fajriman Fathiyyatul Khaira Fedrivia, Rannia Ferdinal Ferry Firdawati Firdawati, Firdawati Gardenia Akhyar Hafni Bachtiar Halida, Erda Mutiara Haris Pemuda Harsby, Carmiyana Puja Hasmiwati Hendra Herizal Hendra Permana Hendra Permana Henny Mulyani henny Mulyani Husna Yetti Husna, Annisa Tamara Ilmiawati Ilmiawati, Ilmiawati Intan, Shinta Ayu Julio, Reyhan Kamelia, Muthia Karmia, Hudila Rifa Khatimah, Gistin Husnul Kiran Nandini Lucy Patmasari Lusi Jelita Sari Madona Utami Dewi MARINGAN DIAPARI LUMBAN TOBING Mayorita, Pamelia Meuthia, Susan Muhammad Zaldy Rasyid Putra Murizal, Thanya Amoret Alya Mustika Sari Muthia Kamelia Nabilla Mahyenda Nadhifa Naura Reyani Najla, Azarine Shidqi Nandini, Kiran Netti Suharti, Netti Nindya Rahmadita Nindya Rahmadita Nisa Ayu Farma Nurhalimah Juneldi Pamelia Mayorita Pemuda, Haris Permata Rachim, Dyan Puja Agung Antonius Puji Anugrah Puti Fajri Lestari Putra, Xavier Novdi Tansyah Rahmadita, Nindya Rahmatini . Restu Susanti Reyhan Julio Ridwan, Laila Hijradesy Rijalul Abrar Rima Semiarty Rosfita Rasyid Rozi Sastra Purna Rudy Setiawan, Muhammad Santy Saberko Sari, Lusi Jelita Savannah, Aisha Selfi Renita Rusjdi Setiawati, Yessy Siregar, Attahhal Fikrian Syadiq Sugeng Santoso Sukri Rahman Timmy Larasati Tofrizal Vaulline Basyir Virgusrudhina, Mitra Wahyuni, Zulfia Wijaya, Caesar Muhammad Yenita . Yenita Afriyeni Yessy Setiawati Yusrawati Yusrawati