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All Journal Pharmaciana: Jurnal Kefarmasian JKPK (Jurnal Kimia dan Pendidikan Kimia) ALKIMIA : Jurnal Ilmu Kimia dan Terapan Jurnal Keperawatan dan Fisioterapi (JKF) Jurnal Kesmas dan Gizi (JKG) JURNAL FARMASIMED (JFM) Jurnal Dunia Farmasi Jurnal Keperawatan Priority JURNAL PENELITIAN PERAWAT PROFESIONAL Jurnal Ilmiah Wahana Pendidikan Jurnal Indah Sains dan Klinis FORTE JOURNAL All Fields of Science Journal Liaison Academia and Sosiety Journal Liaison Academia and Society Jurnal Pengmas Kestra (JPK) Analit: Analytical and Environmental Chemistry Medistra Medical Journal (MMJ) Analit: Analytical And Environmental Chemistry
Herlina H
Institut Kesehatan Medistra Lubuk Pakam
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Journal : JURNAL FARMASIMED (JFM)

 1 
Development Of Body Lotion From Ethanol Extract Of Temulawak (Curcuma Xanthoriza Roxb) As Antioxidant H, Herlina; Desi Paramita; Pitriani; Lasmaryna Sirumapea
Jurnal FARMASIMED (JFM) Vol 6 No 2 (2024): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v6i2.2093

Abstract

Kulit, sebagai bagian terluar dari tubuh dan penjaga utama dari radikal bebas, dapat dilindungi oleh senyawa antioksidan. Lotion tubuh adalah produk kosmetik yang dioleskan pada kulit luar untuk meningkatkan daya tarik. Temulawak (Curcuma xanthoriza Roxb) mengandung senyawa flavonoid yang dapat berfungsi sebagai antioksidan, mencegah kerusakan kulit akibat radikal bebas. Penelitian ini bertujuan untuk menentukan bahwa lotion tubuh yang mengandung temulawak dapat memiliki sifat antioksidan. Penelitian ini meliputi persiapan bahan simplisia, ekstraksi etanol temulawak, pembuatan lotion tubuh dengan ekstrak etanol temulawak, pengujian stabilitas lotion tubuh, dan pengujian aktivitas antioksidan menggunakan metode DPPH. Lotion tubuh dengan ekstrak etanol temulawak pada konsentrasi 0,25%, 0,5%, dan 1% menunjukkan stabilitas pada sifat organoleptik, homogenitas, dan pH. Namun, pengamatan tentang kemampuan penyebaran dan daya lekat menunjukkan bahwa konsentrasi 0,25% lebih baik. Pengujian aktivitas antioksidan lotion tubuh dengan ekstrak etanol temulawak menggunakan konsentrasi 1% untuk mewakili formulasi pada konsentrasi 0,25% dan 0,5% dan memberikan hasil nilai IC50 sebesar 77,6435 ppm. Berdasarkan hasil ini, dapat disimpulkan bahwa ekstrak etanol temulawak (Curcuma xanthoriza roxb) dapat diformulasikan menjadi lotion dan menunjukkan aktivitas antioksidan yang kuat.
Formulation of Body Scrub Containing Ethanol Extract of Temulawak Rhizome (Curcuma xanthorrhiza Roxb) as a Skin Moisturizer H, Herlina; Melda Astrika Sianipar; Yaturramadhan Harahap, Hasni; Aritonang, Barita; Yosi Darmirani
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2650

Abstract

A body scrub is a cosmetic formulation intended to exfoliate dead skin cells and enhance skin hydration. One promising natural ingredient for body scrub formulations is the rhizome of Java turmeric (Curcuma xanthorrhiza Roxb.), which contains curcumin, a potent antioxidant known to support skin moisture retention. This study aims to evaluate the moisturizing efficacy of a body scrub formulated with Java turmeric rhizome extract. Methods: The rhizome was extracted through maceration using 96% ethanol and incorporated into body scrub formulations at concentrations of 10%, 15%, and 20%. The formulations were assessed for organoleptic characteristics, homogeneity, pH, spreadability, adhesion, oisturizing effect, and potential skin irritation on human volunteers. A commercial body scrub served as the comparator in a study involving 12 volunteers over four weeks, with applications performed once per week. Results: All Java turmeric body scrub formulations remained physically stable at room temperature and did not induce skin irritation. The physical characteristics of the formulations met standard cosmetic criteria, including consistent appearance, pH range of 6–7, spreadability between 5–7 cm, adhesion time above 4 seconds, and absence of irritation. Moisturizing effectiveness was evaluated using a skin analyzer, and data were statistically analyzed using SPSS. The p-value of 0.046 indicates that there is a significant difference between F1 and the commercial product, while for F2 and F3, there is no significant difference in moisturizing effectiveness between the temulawak formulations and the commercial product.. Among the tested formulations, the body scrub containing 20% Java turmeric extract exhibited the highest moisturizing effect. Conclusion: The body scrub formulated with Java turmeric rhizome extract, particularly at a concentration of 20%, is safe for use and shows potential as a natural moisturizing product comparable to commercial products on the market.
Reduction of BOD, COD, and TSS in Textile Wastewater Using Bentonite Activated Charcoal Adsorbent Aritonang, Barita; Ritonga, Ahmad Hafizullah; Harefa, Karnirius; H, Herlina
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2699

Abstract

Wastewater generated by the textile industry contains a variety of hazardous contaminants, including complex organic compounds, synthetic dyes, surfactants, heavy metals, and critical pollution indicators such as biochemical oxygen demand (BOD), chemical oxygen demand (COD), and total suspended solids (TSS). This study evaluates the efficacy of a dual-adsorbent system comprising hydrochloric acid-activated bentonite and phosphoric acid-activated carbon for the removal of BOD, COD, and TSS from textile effluents. The activation processes significantly altered the physicochemical properties of both adsorbents. The moisture content of activated carbon decreased from 18% to 3.10%, while ash content was reduced from 15% to 3.05%. The iodine number, indicative of adsorption capacity, increased from 650 mg/g to 810 mg/g. Additionally, the fixed carbon content improved from 55% to 80%. Surface characterization via Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscopy (SEM) confirmed substantial structural modifications, which enhanced the adsorption performance of the materials. Application of the combined adsorbent system resulted in substantial pollutant removal efficiencies, with reductions of 70.23% in BOD, 70.11% in COD, and 74.88% in TSS. These findings demonstrate that acid-activated bentonite and phosphoric acid-treated activated carbon represent a promising and efficient adsorptive treatment strategy for the remediation of textile wastewater.
The Effect of a Combination of Activated Carbon and Bentonite on Reducing COD, BOD, and TSS Levels in Tofu Industry Wastewater Aritonang, Barita; Ritonga, Ahmad Hafizullah; Harefa, Karnirius; Dicky Yuswardi Wiratma; herlina, herlina
Jurnal FARMASIMED (JFM) Vol 8 No 1 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/cbxjb379

Abstract

Wastewater produced from tofu manufacturing typically contains substantial amounts of organic substances and suspended particles. The concentrations of Biochemical Oxygen Demand (BOD), Chemical Oxygen Demand (COD), and Total Suspended Solids (TSS) frequently surpass the permissible thresholds established in the Regulation of the Minister of Environment and Forestry (Permen LHK) No. P.16 of 2019. Such high levels of pollutants may degrade water quality and pose risks to both aquatic ecosystems and public health in nearby areas. This study investigates the efficiency of combining activated carbon and bentonite, in both raw and activated forms, for reducing BOD, COD, and TSS concentrations in wastewater originating from tofu industries. The BOD test was performed using a five-day incubation at 24 °C, COD was analysed via the closed reflux method, and TSS was quantified using the gravimetric approach. Adsorbent characteristics were examined in accordance with the Indonesian National Standard (SNI), supported by functional group analysis using Fourier Transform Infrared (FT-IR) spectroscopy and morphological observation with Scanning Electron Microscopy (SEM). The results demonstrated that activation enhanced pore development and improved the adsorption capability of both materials. The combined activated carbon and bentonite effectively decreased BOD from 3,600 mg/L to 140 mg/L, COD from 1,500 mg/L to 185 mg/L, and TSS from 320 mg/L to 270 mg/L. All treated parameters met the regulatory quality standards, indicating that the activated mixture of these adsorbents provides an efficient and environmentally sound method for treating tofu processing wastewater.
Co-Authors AGNES OCTAVIA DAMANIK Ahmad Hafizullah Ritonga Alinur, Alinur Alwi Fahruzy Nasution ANGELIKA SINAGA Ardi Ardi Aritonang, Barita Asvia Rahayu Asvia Rahayu Barus, Ester Julianti Karolina Buchari Buchari Buchari Buchari Buchari Buchari Buchari Buchari Daulay, Dicky Edwar Desi Paramita Dewi Sartika Munthe Dicky Yuswardi Wiratma Efrizah, Doni Felix Kasim Fransiskus Gultom, Fransiskus Hani, Sheila Harahap, Fitri Ramadani Harahap, Mutiara Hatni Hasni Yaturramadhan Harahap Helman Helman, Helman Hetty Elfina Hilma Hilma, Hilma julian, julian Karnirius Harefa Lasmaryna Sirumapea Lasmaryna Sirumapea Lubis, Basyariah Lumban Batu, Fider Maryani Maryani Masitah, Tina Herianty Melda Astrika Sianipar Mellinda, Mellinda Misdawati, Misdawati Muhammad Ali Zulfikar Muhammad Ali Zulfikar Muhammad Razali Muthawali, Dede Ibrahim Napitupulu, Erni Malinda Nasution, M.Dandy Resafahlevi Novi Yanti Nurlela Petra Saragih Nursaputri, Ika Pitriani Pranata, Chandra Razali, Muhammad RINI RINI Rizqa Hafizhah Harahap Rotua Sumihar Sitorus Samah, Eri Shofian Syarifuddin Sibuea, Nurhalimah Sinambela, Megawati Sirait, Reni Aprinawaty Siregar, Imanuddin Sirumapea Sirumapea Suprianto Suprianto Supriono Supriono Suwianto, Suwianto Tarigan, Purnaya Sari Teja Rinanda Widyaningsih, Fadlilah Yana, Sri Nur Yaturramadhan Harahap, Hasni Yosi Darmirani Yusri Yusri