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SKRINING MYCOBACTERIUM TUBERCULOSIS DENGAN PENGECATAN ZIEHL NEELSEN PADA PELAJAR PONDOK PESANTREN NURUL IMAN DI KOTA JAMBI Karolina, Maria Estela; Lipinwati, Lipinwati; Nuriyah, Nuriyah; Siregar, Mara Imam Taufiq; Hestiningtyas, Maya
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 7 No. 1 (2024): MEDIC. Medical dedication
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/medicaldedication.v7i1.32974

Abstract

ABSTRACTMycobacterium tuberculosis is a group of rod-shaped bacteria and acid-fast bacteria that cause infections in the respiratory system or in other body parts such as the brain and bones. Microscopic examination is the easiest, inexpensive and specific examination and can be carried out in all laboratories. For this reason, microscopic examination is the key in carrying out TB control and prevention programs in establishing the diagnosis and evaluation of treatment for TB patients, namely by Ziehl Neelsen staining. Pondok is a dense dwelling and makes Islamic boarding schools often experience health problems. Insufficient ventilation and low sunlight so that the humidity in the room is quite high. Based on this, tuberculosis screening in Islamic boarding schools is important to do. The implementation of this service was carried out at the Nurul Iman Islamic Boarding School, Jambi City, with inclusion criteria for sputum examination with Ziehl Neelsen staining. Staining was carried out in the biomedical laboratory of FKIK UNJA. 23 sputum samples for TB screening did not find Mycobacterium tuberculosis infection with more sample characteristics of male samples with cough <2 weeks. Mycobacterium tuberculosis was not found in students of the Nurul Iman Islamic Boarding School, Jambi City.Keywords: Islamic boarding school, Mycobacterium tuberculosis, Ziehl Nelsen, Sputum ABSTRAKMycobacterium tuberculosis adalah golongan bakteri berbentuk batang dan bakteri tahan asam yang menyebabkan infeksi pada system pernapasan atau pada bagian tubuh yang lain seperti otak dan tulang. Pemeriksaan mikroskopis merupakan pemeriksaan yang paling mudah, murah dan spesifik dan dapat dijalankan di semua laboratorium. Untuk itu pemeriksaan mikroskopis merupakan kunci dalam menjalankan program pengendalian dan pencegahan TB dalam menegakkan diagnosis dan evaluasi pengobatan penderita TB yaitu dengan pengecatan Ziehl neelsen. Pondok merupakan hunian yang padat dan membuat pondok pesantren sering mengalami masalah kesehatan. Ventilasi yang kurang cukup serta cahaya matahari yang rendah sehingga meningkatkan kelembaban di kamar cukup tinggi. Berdasarkan hal tersebut skrining pemeriksaan tuberkulosis di pondok pesantren penting untuk dilakukan. Pelaksanaan pengabdian ini dilakukan di Pondok pesantren Nurul iman Kota jambi, dengan kriteria inklusi untuk dilakukan pemeriksaan sputum dengan pewarnaan Ziehl neelsen. Pewarnaan dilakukan di laboratorium biomedik FKIK UNJA. 23 sampel sputum untuk skrining TB tidak ditemukan infeksi Mycobacterium tuberculosisdengan karakteristik sampel lebih banyak sampel laki-laki dengan batuk <2 minggu. Tidak ditemukan Mycobacterium tuberculosis pada pelajar Pondok pesantren Nurul Iman Kota Jambi.Kata kunci: Pondok pesantren, Mycobacterium tuberculosis, Ziehl Neelsen, Sputum
THE RELATIONSHIP BETWEEN TREATMENT PHASE AND NUTRITIONAL STATUS IN ADULT TUBERCULOSIS PATIENTS AT PUBLIC HEALTH CENTERS IN JAMBI CITY Wulandari, Putri Sari; Karolina, Maria Estela; Hanina; Lipinwati
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 11 No. 3 (2023): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan Special Issues: Jambi M
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jmj.v11i3.27478

Abstract

Background: Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis. Treatment of tuberculosis consists of two phases, the intensive phase for 2 months and the continuation phase for 6-12 months. One of the factors associated with tuberculosis is nutritional status. If the patient has poor nutritional status, the risk of being infected with tuberculosis will increase. Likewise, if a patient is infected with tuberculosis, the risk of suffering from malnutrition will increase due to the side effects of taking anti-tuberculosis drugs and increased metabolism from Mycobacterium tuberculosis infection. This has a huge influence on the patient's recovery. Objective: This study aimed to investigate the relationship between treatment phase and nutritional status in adult tuberculosis patients at Public Health Centers in Jambi City. Methods: This study is an analytic type of research using a cross sectional design. This research was conducted in several Public Health Centers in Jambi City from July to October 2022. Nutritional status was assessed based on the value of Body Mass Index (BMI). The relationship between treatment phase and nutritional status was analyzed using the chi-square test. Results: The number of samples in this study were 71 patients consisting of 90.1% pulmonary TB patients and 9.9% extra pulmonary TB patients. A total of 59.2% of patients were in the intensive phase of treatment and the majority of patients had underweight nutritional status (60.6%). The results of statistical analysis obtained p value < 0.001. Conclusion: There is a relationship between treatment phase and nutritional status in adult tuberculosis patients at the Public Health Centers in Jambi City. Keywords: tuberculosis, nutritional status, treatment phase, Jambi
Uji Beda Leukosit dan NLR (Neutrophil Lymphocyte-Ratio) terhadap Luaran Pasien Sepsis Rawat ICU (Intensive Care Unit) RSUD Raden Mattaher Jambi 2019 - Oktober 2022 Aidil Rahmat Ilham; Lipinwati, Lipinwati; Ahmad Syauqy; Samsirun Halim; Sotianingsih, Sotianingsih; Ekaputri, Tia Wida
Journal of Medical Studies Vol. 4 No. 1 (2024): Journal of Medical Studies
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/joms.v4i1.31935

Abstract

ABSTRACT Background: Sepsis is a clinical syndrome caused by an overreaction of the body's immune response stimulated by microbes or bacteria inside and outside the body. There is visible organ dysfunction. Of an increase of 2 or more scoresSequential Organ Failure Assessment (SOFA). Early diagnosis and treatment by assessing inflammatory factors such as leukocytes and NLR (Neutrophil-to-lymphocyte ratio). This study aims to determine the difference between leukocyte levels and NLR values based on the outcome of septic patients. Method: This study used an analytic observational cohort method with a retrospective and prospective approach involving 54 research subjects, using consecutive sampling. Sampling was done by calculating leukocyte levels and NLR values at 0, 24, 72, and 144 hours in septic patients. Results: The patients who died for more than 24 hours were 36 patients. The highest average results were measured at 24 hours, with leukocytes 17.48 ± 8.49 and NLR 24.96 ± 22.17. The mean leukocyte and NLR levels were higher in the death group. The analysis found no significant difference between the leukocyte and NLR with the outcomes in septic patients (p >0.05). Conclusion: There was no significant difference between leukocytes and NLR with the outcome of septic patients. Keywords: Biomarkers, Leukocytes, Mortality, NLR, Sepsis   ABSTRAK Latar Belakang: Sepsis adalah suatu sindrom klinik oleh karena reaksi yang berlebihan dari respon imun tubuh yang distimulasi mikroba atau bakteri dari dalam dan luar tubuh. Terdapat disfungsi organ yang terlihat. dari peningkatan 2 atau lebih skor Sequential Organ Failure Assessment (SOFA). Diagnosis dan penanganan lebih awal dengan menilai faktor inflamasi seperti leukosit dan NLR (Neutrophil-to-lymphocyte rasio). Penelitian ini bertujuan untuk mengetahui perbedaan antara kadar leukosit dan nilai NLR berdasarkan luaran pasien sepsis. Metode: Penelitian ini menggunakan metode analitik observasional kohort, dengan pendekatan retrospektif dan prospektif yang melibatkan 54 subjek penelitian, menggunakan teknik consecutive sampling. Pengambilan sampel dilakukan dengan cara menghitung kadar leukosit dan nilai NLR pada jam ke-0, 24, 72, dan 144 pada pasien sepsis. Hasil: Dari 54 sampel, hasil luaran pasien meninggal lebih banyak pada jam 24 sebanyak 36 pasien. Rerata hasil tertinggi pada pada pengukuran jam 24 dengan Leukosit 17,48±8,49 dan NLR 24,96±22,17. Rerata kadar leukosit dan nilai NLR lebih tinggi pada kelompok luaran meninggal. Hasil analisis tidak terdapat perbedaan yang signifikan antara Leukosit dan NLR dengan luaran pasien sepsis (p >0,05). Kesimpulan: Tidak terdapat perbedaan yang signifikan antara Leukosit dan NLR terhadap luaran pasien sepsis. Kata Kunci: Biomarker, Leukosit, Mortalitas, NLR, Sepsis
Perbandingan Jumlah Koloni Bakteri pada Pasien Fraktur Terbuka Pre-operasi dan Post-operasi Miftahul Jannah; Maria Estela Karolina; Nindya Aryanty; Lipinwati; Mirna Marhami Iskandar
Journal of Medical Studies Vol. 4 No. 1 (2024): Journal of Medical Studies
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/joms.v4i1.32090

Abstract

ABSTRACT Background: Open fracture is a structural break in the continuity of bone tissue which can relate to the environment of the body that is susceptible to infection. The World Health Organization (WHO) explains that surgical wound infections are infections that occur within 30 days postoperatively. This study aims to compare the number of bacterial colonies in pre and postoperative open fracture patients. Method: This research is a prospective observational analytic with quantitative methods. Sampling was taken by taking pre and postoperative wound swabs of open fracture patients and counting the number of bacterial colonies. Results: The study sample consisted of 23 samples, consisting of men (100%), the largest age range between 20-60 years (73.9%), the most common trauma mechanism was traffic accidents (52.2%) and the most location was the lower extremities (56,4%). The incidence of infection found 20 patients (87%) had preoperative infections and all patients (100%) had no infections 3 days postoperatively. The results of the Wilcoxon test showed a significant difference between the number of bacterial colonies in pre and postoperative open fracture patients (p<0.05). Conclusion: There were differences in the number of bacterial colonies in preoperative and postoperative open fracture patients. Keywords: Bacterial colony count, Open fractures, Surgery ABSTRAK Latar belakang: Fraktur terbuka merupakan terputusnya kontinuitas jaringan tulang secara struktural yang dapat berhubungan dengan lingkungan luar tubuh sehingga rentan terjadi infeksi. World Health Organization (WHO) menjelaskan bahwa infeksi luka operasi adalah infeksi yang terjadi dalam 30 hari paska operasi. Tujuan penelitian ini adalah untuk membandingkan jumlah koloni bakteri pada pasien fraktur terbuka pre dan post operasi. Metode: Penelitian ini merupakan penelitian analitik observasional pendekatan prospektif dengan metode kuantitatif. Pengambilan sampel dengan mengambil swab luka pasien fraktur terbuka pre dan post operasi dan dilakukan penghitungan jumlah koloni bakterinya. Hasil: Sampel penelitian ini berjumlah 23 sampel, terdiri atas laki-laki (100%), rentang usia terbanyak adalah 20-60 tahun (73,9%), mekanisme trauma tersering adalah kecelakaan lalu lintas (52,2%), dan lokasi terbanyak adalah ekstremitas bawah (56,4%). Kejadian infeksi dari total sampel penelitian didapatkan 20 pasien (87%) mengalami infeksi pre operasi dan seluruh pasien (100%) tidak mengalami infeksi 3 hari post operasi. Hasil uji Wilcoxon menunjukkan adanya perbedaaan yang signifikan antara jumlah koloni bakteri pasien fraktur terbuka pre dan post operasi (p<0,05). Kesimpulan: Terdapat perbedaan jumlah koloni bakteri pada pasien fraktur terbuka pre operasi dan post operasi. Kata kunci: Jumlah koloni bakteri, Fraktur terbuka, Operasi
Correlation of IL-10 Levels with the Bacterial Index in Multibacillary Leprosy Fitriyanti, Fitriyanti; Lipinwati, Lipinwati; Istarini, Attiya; Ekaputri, Tia Wida
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 13 No. 2 (2025): JAMBI MEDICAL JOURNAL: Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jmj.v13i2.48898

Abstract

Background: Multibacillary (MB) leprosy features high bacillary load and an immunoregulatory milieu. Methods: A comparative cross-sectional study enrolled 70 participants (MB = 35; controls = 35). Categorical variables were compared with Chi-square/Fisher’s exact tests; medians with Mann–Whitney U. Spearman’s rank correlations were computed within groups. Results: Age did not differ (p = 0.458 and p = 1.000), whereas occupation and education did (p = 0.038 and p = 0.029). The Bacterial Index (BI) was markedly higher in MB (median 3 [IQR 4]) than controls (0 [0]; p < 0.001). IL-10 levels were higher in MB (1.97 [4.30] pg/mL) versus controls (1.12 [1.96] pg/mL; p = 0.033). In MB, BI correlated positively with IL-10 (ρ = 0.357; p = 0.035). Conclusions: MB patients exhibit substantially higher bacillary burden and elevated IL-10 relative to controls. The positive BI–IL-10 association in MB supports a tolerogenic immune profile linked to bacterial load, while PGE₂ showed limited discriminatory value in this sample. Larger, adjusted studies are warranted to validate these relationships and explore their clinical utility.
INTERACTIVE VISUAL EDUCATION TO ENHANCE KNOWLEDGE OF LOW BACK PAIN AMONG THE ELDERLY AND CAREGIVERS AT OLAK KEMANG HEALTH CARE, JAMBI CITY Humaryanto, Humaryanto; Attiya istarini; Lipinwati, Lipinwati; Perkasa, Tengku Arief Buana; Ahmad Syauqy; Hasna Dewi; Fitriyanti; Juanda, Syahreza Hadi; Zikri, Rahmat
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 8 No. 2 (2025): MEDIC. Medical dedication
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Low back pain is a common degenerative illness among the elderly, significantly impacting their quality of life and independence. Insufficient understanding of effective management frequently worsens the disease. The objective of this community service program was to enhance comprehension of low back pain among elderly and their caregivers at the Olak Kemang Public Health Centre in Jambi City. The programme consisted of an instructional session with 41 participants utilising a multidisciplinary-developed interactive visual module, accompanied by a practical demonstration of stretching exercises. A pre- and post-test design was used to quantitatively evaluate the alteration in participants' knowledge. The data were examined with the Wilcoxon and Pearson chi-square tests. The findings indicated a statistically significant enhancement in participants' knowledge, with the median score increasing from 60 (range: 30-80) in the pre-test to 85 (range: 50-100) in the post-test (p < 0.001). The number of participants who attained a passing score (≥70%) rose considerably from 19 to 31 (p = 0.007). The interactive visual education program effectively enhances awareness regarding lowback pain among the elderly and their caregivers. This strategy is highly recommended for implementation in other community health programs. Keywords: Low back pain; caregiver; health education; elderly
Relationship Between the Use of Boots and the Incidence of Tinea Pedis in Motor Vehicle Wash Employees in Jambi City Hasibuan, Fitra Husni Mubarak; Hanina; Aurora, Wahyu Indah Dewi; Lipinwati; Maharani, Citra
Journal of Medical Studies Vol. 5 No. 2 (2025): Journal of Medical Studies
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/joms.v5i2.40683

Abstract

Background: Tinea pedis is a fungal infection of the skin of feet characterized by peeling skin, itching and watery skin. Risk factors for this disease are working in wet places and wearing closed shoes for a long time such as motor vehicle wash service workers. The purpose of this study was to determine the relationship between the use of boots and the incidence of tinea pedis in motor vehicle wash employees in Jambi City. Objective: This study aims to determine the relationship between the use of boots with the incidence of tinea pedis in motorbike wash employees in Jambi City Methods: This quantitative analytical research type with a crosssectional method The research sample was motor vehicle wash employees in Jambi City. The sampling technique used the cluster sampling method, researchers selected groups in each sub-district in Jambi City according to the research criteria as many as 96 samples. Data were obtained using questionnaires, physical examinations and KOH examinations. The data that had been obtained were then processed by computerization using the SPSS application. Results: In this study, it was found that there was a significant relationship between length of work and the incidence of tinea pedis, length of use of boots with the incidence of tinea pedis and foot hygiene with the incidence of tinea pedis. Representatively p-value less than 0.005 (p=0.016) (p=0.000) (p=0.000). Conclusion: The longer working in a humid place, the longer using boots, and the worse foot hygiene a person has increases the risk of getting tinea pedis
The The Correlation of Neutrophil-to-Lymphocyte Ratio with LupusQoL in Systemic Lupus Erythematosus Patients Mahrunnisa Rienti Sepestian; Lipinwati; Dewi, Hasna; Hanina; Nyimas Natasha Ayu Shafira
Journal of Medical Studies Vol. 5 No. 2 (2025): Journal of Medical Studies
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/joms.v5i2.40840

Abstract

Background: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease with diverse clinical manifestations depending on disease activity. Clinical manifestations, disease activity, and side effects of treatment can affect quality of life. The LupusQoL questionnaire assesses the disease's impact on eight quality of life domains. The Neutrophil-to-Lymphocyte Ratio (NLR) is an inflammatory biomarker that correlates with SLE disease activity. Objective: This research aims to determine the correlation between NLR and various domains of the LupusQoL questionnaire in SLE patients. Methods: This observational analytic study used purposive sampling, involving 32 SLE patients treated at Raden Mattaher Hospital, Jambi, in 2024. NLR was obtained from blood counts performed within the last 4 weeks, and HRQOL was measured using the LupusQoL questionnaire. Data were analyzed using Pearson correlation. Result: The mean NLR was 6.50 (1.3–29.43). LupusQoL showed the lowest score in fatigue (58.85). Pearson analysis revealed a moderate inverse correlation between NLR and the planning domain of LupusQoL (p= 0,022). NLR shows no statistically significant correlation with physical health, pain, intimacy, burden to others, emotional health, body image, or fatigue in SLE patients, as p-values >0.05. Conclusion: Higher NLR is correlated with lower planning domain HRQoL in SLE patients and vice versa.