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Kliniko-Sitopatologi Lesi Prekanker Leher Rahim di Klinik Unja Smart Desa Mendalo Darat Kabupaten Muaro Jambi Fairuz, Fairuz; Dewi, Hasna; Nuriyah, Nuriyah; Lipinwati, Lipinwati; Ayudia, Esa Indah; Lestari, Nur Afni
Jurnal Karya Abdi Masyarakat Vol. 5 No. 3 (2021): Jurnal Karya Abdi Masyarakat
Publisher : LPPM Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (454.739 KB) | DOI: 10.22437/jkam.v5i3.16281

Abstract

Kanker serviks merupakan suatu keganasan yang berkembang di daerah leher rahim. Hampir semua kasus, sebesar 99%, terkait dengan infeksi HPV resiko tinggi. Di Indonesia, angka kejadian kanker berada pada urutan ke-8 di Asia Tenggara, dan urutan ke-23 di Asia. Salah satu skrining kanker serviks yang dapat dilakukan yaitu tes pap smear. Tujuan dari penelitian ini adalah untuk melihat gambaran klinis dan gambaran sitopatologi lesi prekanker leher rahim sesuai dengan klasifikasi Bethesda 2014. Lokasi kegiatan dilakukan di Klinik Unja Smart, Mendalo, Kabupaten Muaro Jambi. Variabel klinis yang dinilai adalah usia, paritas, jenis kontrasepsi, menopause, keluhan, riwayat ginekologi dan status lokalis, sedangkan variabel sitopatologinya adalah gambaran lesi prekanker leher rahim menurut kriteria Bethesda 2014. Didapatkan dari kriteria klinis usia rata-rata adalah 40 tahun, multipara, tidak menggunakan KB dan keluhan terbanyak adalah keputihan. Hasil sitopatologi pap smear terbanyak adalah Negative for intraepithelial lesion or malignancy NILM dan diikuti oleh Servisitis kronis non spesifik (CKNS) di urutan kedua. Kesimpulannya adalah gambaran kliniko-sitopatilogi masih menunjukkan keadaan yang normal.
Mycobacterium Tuberculosis Identification on Suspected Extra Pulmonary Tuberculosis Patients Lipinwati, Lipinwati; Hanina, Hanina; Wulandari, Putri Sari; Iskandar, Mirna Marhami; Istarini, Attiya; Miranda, Melly; Dewi, Hasna; Juniati, Rianita; Fairuz, Fairuz
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 13 No. 1 (2025): JAMBI MEDICAL JOURNAL: Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jmj.v13i1.38458

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Background: Extra Pulmonary Tuberculosis (EPTB) is Tuberculosis infection in organs other than the lungs, like pleura, lymph nodes, abdomen, genitourinary tract, skin, joints and bones, or meninges. The Diagnosis of EPTB is still challenging because symptoms of EPTB is vary, location EPTB is an inaccessible site, and paucibacillary smear. We wanted to know the Mycobacterium tuberculosis identification using the qPCR method on samples of EPTB suspects. Methods: This research was a descriptive research with laboratory experiments. Subjects in this study were all cases of suspected EPTB with clinically diagnosed, thoraks radiographs, colonoscopy, and formalin fixed paraffin embedded (FFPE). DNA extraction was carried out according to  PureLink® Genomic dna extraction kit instructions. The PCR volume 20 ul with 2x QuantiNova SYBR Green PCR Kit, M.tuberculosis Primer IS 6110, and DNA Sample. QPCR temperatures was done with predenaturation at 95 °C for 3 minutes, and followed 45 cycles, consist of denaturation at 95 °C for 15 seconds, annealing at 60 °C for 30 seconds dan extenstion at 72 °C for 30 seconds. PCR was performed with positive and negative controls, and data analysis was based on positive and negative ct controls. Results: From 30 suspect EPTB samples, there are males (56,67%), with age 36-55 yo (50%), site of samples most from gastrointestines (70%), and there are 6 samples (20%) with positive qPCR. Conclusion: qPCR methods can be used for EPTB diagnosis.
Antimicrobial effect of alkaloids extract of Areca catechu L Against Methicillin Sensitive Staphylococcus aureus Bacteria Humaryanto, Humaryanto; Lipinwati, Lipinwati; Hanina, Hanina; Halim, Rita
Riset Informasi Kesehatan Vol 14 No 2 (2025): Riset Informasi Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30644/rik.v14i2.871

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Background: Infection caused by the bacterium Metihcillin Sensitive Staphyloccous aureus (MSSA) is still one of the infections that often occurs in humans. The emergence of various cases of resistance of MSSA bacteria to various antibiotics both in the community and in hospitals (nosocomial infections), has triggered the development of herbal medicines, one of which is the areca nut (Areca catechu L) which is thought to have antibacterial effects. The purpose of this research was to determine the antimicrobial effect of alkaloids in areca nut extract against MSSA bacteria. Method: Areca nut was extracted with 96% ethanol using the maceration method and continued with areca nut seeds and fractionation of the alkaloid active substances with ethanol-water, n-hexane and ethyl acetate (1:1) solvents. The sensitivity test of bacteria using the Kirby Bauer disc diffusion method with duplex repetitions. Amoxcillin clavulanat used as standard antimicrobial of antimicrobial test. Results: The extract components contained are alkaloids, flavonoids and tannins. Furthermore, the resistance test of MSSA bacteria to areca nut alkaloid extract and the amoxicillin antibiotic disc gave results of an average inhibitory zone diameter of 20.33 mm (strong activity) and 22.80 mm (strong activity). Conclusion: MSSA bacteria showed sensitivity to areca nut alkaloid extract with strong activity.
HANDS ON TRAINING FOR PRE-ANALYTIC SAMPLE OF HISTOPATHOLOGY AND CYTOLOGY EXAMINATION IN JAMBI CITY Quzwain, Fairuz Chatib; Dewi, Hasna; Lipinwati; Hanina; Miftahurrahma
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 8 No. 1 (2025): MEDIC. Medical dedication
Publisher : Universitas Jambi

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Abstract

The pre-analytic stage is an important stage in the anatomical pathology examination. in the specimen are prepared by the assistant nurse surgeon or clinician or laboratory analyst who receives the cytology sample, so it is necessary to provide correct and appropriate information for them and training in handling these samples is carried out. This activity is carried out to improve the understanding of health workers in managing samples and tissues at the pre-analytical stage. In this training, a standard operating procedure (SOP) for pre-analytical handling of histopathology and cytology samples will also be prepared, which is expected to be recognized by the association as an SOP for its members that applies in Jambi province. The method implemented is direct training on tissue and fluid samples and evaluation is carried out by assessing the pre-test and post-test after the activity is carried out. The results of the activity assessment showed a significant increase in the understanding and knowledge of the participants in the activity by looking at the increase in the pre-test and post-test scores. There is an increase in the understanding and knowledge of the training participants regarding the management of tissue and fluid samples at the pre-analytical stage.
MANAGEMENT OF SCABIES IN ISLAMIC BOARDING SCHOOLS: DEVELOPMENT OF EARLY DETECTION CADRES WITHIN THE TAHTUL YAMAN COMMUNITY HEALTH CENTER AREA, JAMBI CITY, 2024 Hanina; Fitriyanti, Fitriyanti; Lipinwati; Hasna Dewi; Ahmad Syauqy; Attiya Istarini; Ivo Amrina Rasyada
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 8 No. 1 (2025): MEDIC. Medical dedication
Publisher : Universitas Jambi

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Abstract

ABSTRACT Scabies is a skin disease that is often found in Indonesia caused by Sarcoptes scabei. The prevalence of scabies in Islamic boarding school environments in Jambi is around 4.9%. Sandra Widaty et al. from the Faculty of Medicine, University of Indonesia, have developed a Deskab (Early Detection of Scabies) form that can be used by ordinary people (cadres) very easily, and the results are relatively similar to those carried out by medical personnel. The method is to present cadres and resource persons, conduct a pretest, provide scabies material, posttest, and training on how to directly apply the Deskab form by cadres and be assessed by a doctor. There were 18 participants from four Islamic boarding schools. The majority of participants were male (67%) and adults (19-59 years) (67%). The average pretest and posttest score was 79.64 (80%) and 83.78 (83%). The average score for the Deskab results is 95.12 (95%), and all cadres have a score above 79. All cadres are declared to have passed and are expected to be able to carry out early detection screening on santri so that efforts to control scabies in the work area of the Tahtul Yaman Health Center can be realized as planned. Keywords: scabies, Deskab, cadre, boarding school
EVALUATION OF BLOOD PRESSURE, CHOLESTEROL, GLUCOSE, AND URIC ACID LEVELS IN PATIENTS AT THE OLAK KEMANG HEALTH CENTRE IN JAMBI CITY Attiya Istarini; Lipinwati; Hasna Dewi; Wulandari, Putri Sari; Samsirun Halim; Amatullah, Afifah; Hafizah; Denok Tri Hardiningsih
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 8 No. 1 (2025): MEDIC. Medical dedication
Publisher : Universitas Jambi

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Abstract

ABSTRACT Hypertension is a chronic elevation of systemic arterial pressure beyond a level that may damage the endothelium. Individuals with hypertension typically demonstrate increased levels of blood glucose, cholesterol, and uric acid. Hyperlipidemia, age, and hypertension exhibit a complicated interplay that profoundly influences cardiovascular risk. Inadequate management of blood pressure and insufficient public awareness regarding the early detection of metabolic syndrome continue to significantly worsen the global prevalence of cardiovascular disease.This community service initiative assessed blood pressure and blood chemistry to identify early risk factors for cardiovascular disease. Olak Kemang Health Centre, affiliated with Jambi University's Faculty of Medicine and Health Sciences, conducts community service projects. Patients of the Regular Olak Kemang Health Center engaged in this research. Following an 8-hour fasting period, all individuals underwent assessments of their blood pressure, cholesterol levels, glucose, and uric acid concentrations. This study evaluated the blood pressure and clinical chemistry of 44 subjects. Seven patients (15.9%) exhibited pre-hypertension, twelve (27.3%) presented with stage 1 hypertension, and eleven (25%) were diagnosed with stage 2 hypertension. The majority of individuals with hypertension were aged 46 to 55 years. In the community service, 4 participants exhibited elevated uric acid levels, 9 had elevated glucose levels, and 7 had elevated cholesterol levels. Eight patients with stage 1 hypertension exhibited higher blood chemistry levels. Considering that glucose, cholesterol, and uric acid are associated with cardiovascular disease risk, it is advisable for patients with hypertension to have their levels regularly monitored. Their connection highlights the need for integrated management strategies to improve patient care and prevent complications.  Keywords: Elderly, Hypertension, Hyperlipidemia, Hyperglicemia, Hyperuricemia.   ABSTRAK Hipertensi adalah peningkatan kronis tekanan arteri sistemik di atas level yang dapat merusak endotelium pembuluh darah. Individu dengan hipertensi biasanya menunjukkan peningkatan kadar glukosa darah, kolesterol, dan asam urat. Hiperlipidemia, usia, dan hipertensi menunjukkan interaksi yang meningkatkan resiko kejadian penyakit kardiovaskular. Manajemen tekanan darah yang tidak memadai dan kurangnya kesadaran publik mengenai deteksi dini sindrom metabolik terus memperburuk prevalensi penyakit kardiovaskular global secara signifikan. Kegiatan pengabdian masyarakat ini bertujuan untuk pemeriksaan tekanan darah dan kimia darah untuk mengidentifikasi lebih awal faktor risiko penyakit kardiovaskular. Kegiatan ini diinisiasi oleh Fakultas kedokteran dan Ilmu Kesehatan Universitas Jambi bekerja sama dan dilaksanakan di Puskesmas Olak Kemang Kota Jambi. Pasien Puskesmas Reguler Olak Kemang terlibat dalam kegiatan ini. Setelah puasa selama 8 jam, semua individu menjalani penilaian tekanan darah, kadar kolesterol, glukosa, dan konsentrasi asam urat. Studi ini mengevaluasi tekanan darah dan kimia klinis dari 44 peserta. Tujuh orang (15,9%) menunjukkan pra-hipertensi, dua belas orang (27,3%) menunjukkan hipertensi stadium 1, dan sebelas orang (25%) didiagnosis hipertensi stadium 2. Mayoritas individu dengan hipertensi berusia 46 hingga 55 tahun. Dalam pengabdian masyarakat, empat orang menunjukkan peningkatan kadar asam urat, sembilan orang memiliki peningkatan kadar glukosa, dan tujuh orang memiliki peningkatan kadar kolesterol. Delapan pasien dengan hipertensi stadium 1 menunjukkan kadar kimia darah yang lebih tinggi. Mengingat bahwa glukosa, kolesterol, dan asam urat berhubungan dengan risiko penyakit kardiovaskular, disarankan bagi pasien hipertensi untuk memantau kadar kimia darah secara teratur. Hubungan antara hipertensi dan sindrom metabolik menunjukkan perlunya strategi manajemen terpadu untuk meningkatkan perawatan pasien dengan hipertensi dan mencegah komplikasi. Kata kunci: Lansia, Hipertensi, Hiperlipidemia, Hiperglikemia, Hiperurisemia
The Relationship Between Carbohydrate Intake and Physical Activity with Body Mass Index in Medical Students Suzan, Raihanah; Syofira, Novianti; Lipinwati, Lipinwati; Halim, Rita; Istarini, Attiya
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 13 No. 1 (2025): JAMBI MEDICAL JOURNAL: Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jmj.v13i1.41056

Abstract

Background: The Body Mass Index (BMI) of medical students is influenced by dietary habits, lifestyle choices, and socio-cultural factors. The unique lifestyle and academic pressures faced by medical students make it essential to understand the relationship between carbohydrate intake, physical activity, and BMI in this population. Methods: This cross-sectional analytical study was conducted among 102 medical students at Jambi University, selected through purposive sampling. Data were collected using the International Physical Activity Questionnaire (IPAQ), a 2x24-hour food recall questionnaire, and anthropometric measurements of height and weight. Statistical analysis was performed using the Spearman correlation test. Results: The majority of respondents had low carbohydrate intake (85.3%), moderate physical activity levels (52.9%), and normal BMI (44.1%). Spearman correlation analysis showed no significant relationship between carbohydrate intake and BMI (p = 0.3, r = 0.1). However, a statistically significant negative correlation was found between physical activity and BMI (p < 0.001, r = -0.43), indicating that higher physical activity levels are associated with lower BMI. Conclusion: This study found no significant relationship between carbohydrate intake and BMI but identified a negative correlation between physical activity and BMI among medical students. These findings highlight the importance of promoting physical activity as the key factor in maintaining a healthy BMI.
HUBUNGAN KADAR GULA DARAH SEWAKTU DENGAN NEUROPATI DIABETIK PADA PASIEN DIABETES MELITUS TIPE 2 Lisa, Mei; Lipinwati, Lipinwati; Istarini, Attiya; Syauqy, Ahmad; Shafira, Nyimas Natasha Ayu
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 41 No 4 (2025): Volume 41 Nomor 4, September 2025
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v41i4.721

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ABSTRACT Introduction: Diabetes mellitus can cause microvascular complications, one of the most common being neuropathy, which is triggered by persistent hyperglycemia. Aims: To determine the relationship between random blood glucose levels and the incidence of diabetic neuropathy in Type 2 Diabetes Mellitus patients. Methods: This analytical observational study used a cross-sectional design involving 92 Type 2 Diabetes Mellitus patients. Neuropathy was assessed using the DNS-Ina questionnaire, while random blood glucose levels were obtained through laboratory tests. Data were analyzed using the Chi-square test. Results: Among the respondents, 53.3% did not experience hyperglycemia, while 82.3% had diabetic neuropathy. The Chi-square test revealed a p-value of 0.017 with an odds ratio of 4.568, indicating a significant association between random blood glucose levels and diabetic neuropathy. Conclusion: There is a significant relationship between random blood glucose levels and the incidence of diabetic neuropathy in Type 2 Diabetes Mellitus patients at H. Abdul Manap Regional Hospital, Jambi City. Keywords: diabetic neuropathy, random blood glucose, Type 2 diabetes mellitus
INFLAMASI BOWEL DISEASE Lipinwati, Lipinwati
Scientific Of Environmental Health and Diseases Vol. 2 No. 1 (2022): Scientific of Environmental Health And Diseases
Publisher : LPPM Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (240.655 KB) | DOI: 10.22437/esehad.v2i2.16919

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ABSTRACT Inflammatory Bowel Disease (IBD) is one of public health problems because it will affect patient education, work ability and related with quality of life. IBD is a chronic recurrent inflammation of the small intestine and colon with unknown etiology, with symptoms mild to severe abdominal pain and diarrhea. IBD is divided into 2 types: one is Crohn's disease (CD) which often occurs in the ileum (can extend to the entire gastrointestinal tract) with symptoms of abdominal pain, diarrhea, vomiting and weight loss, and two is Ulcerative colitis (UC) which is characterized by progressive inflammation. in the gastrointestinal tract and colonic mucosa. The etiology of IBD is suspected result of a complex interaction between genetics, role of the gut microbiota, immune system, and specific environmental factors. The pathogenesis of IBD is not clearly known, there is a thought that IBD is caused by a complex role between the gut microbiota, dysregulation of the immune system, role of genetics and environmental factors. Diagnosis is based on history taking, physical examination, supporting examinations such as blood tests, stool cultures, radiological examinations, endoscopic examinations and histopathology. The principle of IBD therapy is treating active IBD inflammation quickly until remission, prevent recurrent inflammation by maintaining remission as long as possible, and treat/prevent complications. The management includes pharmacotherapy, nutrition, surgery and psychotherapy. Keyword: Inflammatory Bowel Disease (IBD), Ulcerative colitis (UC) ABSTRAK Inflamatory Bowel Disease (IBD) merupakan masalah kesehatan masyarakat yang penting karena akan mempengaruhi pendidikan pasien, kemampuan bekerja dan berhubungan dengan kualitas hidupnya. IBD adalah peradangan kronik berulang pada usus halus dan kolon yang belum diketahui penyebabnya dengan gejala sakit perut yang berat dan diare. IBD terbagi atas 2 jenis, yaitu: Crohn’s disease (CD) yang sering terjadi ileum (dapat meluas ke seluruh dinidng saluran cerna) dengan gejala sakit perut, diare, muntah dan penurunan berat badan, dan Ulcerative colitis (UC) yang ditandai dengan peradangan progresif pada sistem saluran cerna dan mukosa kolon. Etiologi IBD secara pasti belum diketahui, diduga IBD merupakan hasil dari interaksi kompleks antara genetik, peran mikrobiota usus, sistem imunitas, faktor lingkungan yang spesifik. Patogenesis IBD secara jelas belum diketahui, adanya pemikiran bahwa IBD disebabkan oleh peran kompleks antara mikrobiota usus, disregulasi sistem imun, peran genetik dan faktor lingkungan. Penegakkan diagnosis berdasarkan anamnesis, pemeriksaan fisik, pemeriksaan penunjang seperti pemeriksaan darah, kultur tinja, pemeriksaan radiologi, pemeriksaan endoskopi dan histopatologi. Prinsip terapi IBD adalah mengobati peradangan aktif IBD dengan cepat sehingga tercapai remisi, mencegah peradangan berulang dengan mempertahankan remisi selama mungkin, dan mengobati/mencegah komplikasi. Manajemen IBD meliputi farmakoterapi, nutrisi, operasi dan psikoterapi. Keyword: Inflamatory Bowel Disease (IBD), Ulcerative colitis (UC)
Faktor-Faktor Risiko Kejadian Tuberkulosis Paru Kambuh Di Puskesmas Kota Jambi Tahun 2020-2022 Natasia Ulfa, Regina; Efendy, Makruf; Halim, Samsirun; Lipinwati, Lipinwati
Scientific Of Environmental Health and Diseases Vol. 3 No. 2 (2023): Scientific of Environmental Health And Diseases
Publisher : LPPM Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/esehad.v4i1.29333

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ABSTRAK Latar Belakang: Tuberkulosis (TB) paru kambuh merupakan salah satu kendala untuk tercapainya target End TB strategy tahun 2030 sehingga perlu penelitian mengenai ini. Tujuan penelitian ini yaitu untuk mengetahui gambaran faktor risiko terjadinya TB paru kambuh di Puskesmas Kota Jambi tahun 2020-2022 Metode: Penelitian ini menggunakan desain deskriptif retrospektif. Sampel dalam penelitian ini berjumlah 22 orang yang diambil dengan menggunakan teknik total sampling. Analisis data yang digunakan yaitu analisis univariat. Hasil: Hasil penelitian faktor risiko kejadian tuberkulosis paru kambuh di Puskesmas kota Jambi tahun 2020-2022 didapatkan sebagian besar penderita yaitu laki-laki (81,8%), usia >34 tahun (77,3%), status sosial ekonomi rendah (81,8%), tingkat pendidikan terakhir SMA (59,1%) dan ada riwayat kebiasaan merokok (55,5%), status gizi normal (59,1%), kepadatan hunian kamar memenuhi syarat (86,4%), riwayat berobat teratur (77,3%), tidak ada penyakit penyerta (68,2%), tidak ada riwayat kontak erat (68,2%), pengetahuan baik (59,1%), sikap yang baik (77,3%) dan dukungan keluarga yang baik (68,2%). Kata Kunci: Faktor risiko, tuberkulosis paru, kambuh