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Formulation and Physicochemical Characterization of a Macroemulsion Containing Ethanolic Extract of Kemuning Leaves (Murraya paniculata (L.) Jack) Weningtyas, Anditri; Wiratama, Arif Ladika; Wibisono, Taurisma Aulia Nanda; Septiananda, Farsya Hidayah; Prastita, Nenes
BIOEDUSCIENCE Vol 10 No 1 (2026): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/20395

Abstract

Background: Ethanolic extract of Murraya paniculata leaves contains several bioactive constituents, but its direct application is limited by physicochemical instability and solubility issues. Objective: This study aimed to formulate and characterize macroemulsions containing ethanolic extract of Murraya paniculata leaves and to identify the most promising formulation based on physicochemical evaluation.   Methods: The extract was prepared by maceration using 96% ethanol. Four macroemulsion formulations were developed using different ratios of virgin coconut oil, Tween 80, PEG 400, and water. The formulations were evaluated through phytochemical screening, organoleptic properties, emulsion type, transmittance, particle size distribution, pH, zeta potential, centrifugation, and cycling test.   Results: The extract contained flavonoids, alkaloids, tannins/phenolics, and triterpenoids. All formulations were identified as oil-in-water emulsions. Based on the reported data, F2 showed high transmittance and a low polydispersity index, while F1 and F2 demonstrated better physical stability than F3 and F4.   Conclusions: The study indicates that F1 and F2 were the most promising formulations; however, the claim of a single best formulation should be supported by complete, consistently presented particle-size, zeta-potential, and stability data.
Nutritional Determinants and Molecular Insights into Anemia among Boarding School Adolescents Kiky Martha Ariesaka; Lintang Widya Sishartami; Anditri Weningtyas; Moh. Mirza Nuryady
Jurnal Kesehatan Masyarakat Vol. 21 No. 3 (2026)
Publisher : Universitas Negeri Semarang in collaboration with Ikatan Ahli Kesehatan Masyarakat Indonesia (IAKMI Tingkat Pusat) and Jejaring Nasional Pendidikan Kesehatan (JNPK)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v21i3.35386

Abstract

Introduction: Anemia remains a significant public health problem among adolescents in developing countries such as Indonesia. Female adolescents are more vulnerable due to menstrual blood loss and increased iron needs during growth, while dietary diversity and beverage habits may further influence anemia risk. Aim: This study aimed to analyze factors associated with anemia, including gender, diet quality, and tea or coffee consumption, and to explore their molecular relevance using a bioinformatics approach. Methods: A cross-sectional study was conducted among 199 adolescents (105 males, 94 females) aged 12–17 years in a boarding school in Malang, Indonesia. Data collection included hemoglobin measurement, anthropometric assessment, and a Food Frequency Questionnaire (FFQ). Statistical analysis was performed using Chi-square and logistic regression, while bioinformatics analysis employed STRING, Cytoscape, and ShinyGO to identify key genes and pathways. Results: Female gender (AOR = 6.595; p < 0.001), adequate diet (AOR = 0.184; p = 0.012), and tea/coffee intake (AOR = 7.532; p < 0.001) were significant predictors of anemia. Bioinformatics analysis identified SLC11A2, TFRC, and HAMP as key genes regulating ferroptosis and mineral absorption pathways. Conclusions: Gender, dietary quality, and tea or coffee consumption significantly influence anemia in adolescents. 
Edukasi dan Skrining Kesehatan sebagai Upaya Deteksi Dini Diabetes Melitus Tipe 2 dan Hipertensi pada Ibu-Ibu PKK di Desa Sumberejo Kecamatan Gedangan Kabupaten Malang Sishartami, Lintang Widya; Weningtyas, Anditri; Ariesaka, Kiky Martha; Haliza, Septiana Nur; Sajidah, Akifah Hanin Najwa; Ahnaf, Ahmad Baihaqi; Nurbin, Afif Radika
Lumbung Inovasi: Jurnal Pengabdian kepada Masyarakat Vol. 11 No. 3 (2026): September
Publisher : Lembaga Penelitian dan Pemberdayaan Masyarakat (LITPAM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/linov.v11i3.6519

Abstract

Diabetes melitus (DM) dan hipertensi merupakan penyakit tidak menular yang memerlukan upaya promotif dan preventif melalui peningkatan pengetahuan serta deteksi dini di masyarakat. Kegiatan pengabdian kepada masyarakat ini bertujuan meningkatkan pengetahuan dan kesadaran ibu-ibu PKK mengenai DM dan hipertensi serta mengidentifikasi kondisi kesehatan melalui skrining glukosa darah dan tekanan darah. Kegiatan dilaksanakan pada 52 ibu-ibu PKK di Desa Sumberejo melalui edukasi kesehatan menggunakan media booklet, pre-test dan post-test, serta pemeriksaan glukosa darah dan tekanan darah. Hasil menunjukkan adanya peningkatan rerata skor pengetahuan meningkat dari 72,50 pada pre-test menjadi 92,69 pada post-test setelah edukasi, dengan perbedaan bermakna (p < 0,001). Hasil skrining glukosa darah sewaktu menunjukkan bahwa 92,3% peserta berada dalam ketagori normal dan 7,7% berada dalam kategori hiperglikemia. Hasil skrining tekanan darah menunjukkan bahwa 30,8% peserta berada dalam kategori normal, 13,5% termasuk hipertensi grade 1, dan 55,8% termasuk hipertensi grade 2. Hasil pemeriksaan disampaikan kepada peserta sebagai umpan balik untuk meningkatkan kesadaran terhadap kondisi kesehatan dan pentingnya pemeriksaan secara berkala karena skrining ini tidak digunakan sebagai diagnosis definitif. Peserta dengan hasil yang memerlukan perhatian lebih lanjut diberikan anjuran untuk melakukan pemeriksaan lanjutan di fasilitas pelayanan kesehatan. Kegiatan ini menunjukkan bahwa integrasi edukasi dan skrining dapat meningkatkan pengetahuan serta membantu peserta mengenali kondisi kesehatan yang memerlukan pemantauan lebih lanjut. Kontribusi ibu-ibu PKK melalui kegiatan ini berpotensi memperkuat peran keluarga dan masyarakat dalam deteksi dini serta pencegahan penyakit tidak menular secara berkelanjutan. Health Education and Screening of Type 2 Diabetes Mellitus and Hypertension among PKK Women in Desa Sumberejo Kecamatan Gedangan Abstract Diabetes mellitus (DM) and hypertension are non-communicable diseases that require promotive and preventive efforts through improving health knowledge and facilitating early detection within the community. This community service activity aimed to improve the knowledge and awareness of PKK women regarding DM dan hypertension and to identify health conditions through blood glucose and blood pressure screening. The activity involved 52 PKK women in Desa Sumberejo and consisted of health education using a booklet, pre-test and post-test assessments, blood glucose and blood pressure measurements. The results demonstrated that the mean knowledge score increased from 72,50 at pre-test to 92,69 at post-test, with a statistically significant difference (p < 0,001). Random blood glucose screening showed that 92,3% of participants had results within the normal category and 7,7% had results categorized as hyperglycemia. Blood pressure screening showed that 30,8% pf participants had normal blood pressure, 13,5% were classified as having grade 1 hypertension, and 55,8% as having grade 2 hypertension. The screening results were communicated to participants as direct feedback to increase awareness of their health status and the importance of regular health monitoring, as the screening was not intended to provide definitive diagnosis.Participants with findings requiring further attention were advised to undergo follow-up examintaions at healthcare facilities. These findings demonstrate that integrating health education and screening can improve knowledge while enabling participants to recognize health conditions requiring further monitoring. The involvement of PKK women through this activity has the potential to strengthen the role of families and communities in the early detection and prevention of non-communicable diaseases in a sustainable manner