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All Journal Media Kesehatan Masyarakat Indonesia Sains Olahraga : Jurnal Ilmiah Ilmu Keolahragaan JBIO: jurnal biosains (the journal of biosciences) Media Ilmu Keolahragaan Indonesia Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Journal of Biomedicine and Translational Research Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat Kinestetik : Jurnal Ilmiah Pendidikan Jasmani Journal of Saintech Transfer Sumatera Medical Journal Jurnal Ners AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh SCRIPTA SCORE Scientific Medical Journal Jurnal Syntax Fusion : Jurnal Nasional Indonesia Ophthalmologica Indonesiana
Yetty Machrina
Department Of General Medicine, Faculty Of Medical, Universitas Sumatera Utara, Medan, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Education Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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Identifying the Burden of Digital Eye Strain: Prevalence, Clinical Manifestations, and Risk Factors in Indonesian Medical Students Zega, Elwande Hagasaro; Selly Azmeila; Yetty Machrina; Kamal Basri Siregar
Majalah Oftalmologi Indonesia Vol 52 No 1 (2026): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/oi.v52i1.101960

Abstract

Introduction: The increasing use of digital devices among university students, particularly in medical education, has raised concerns regarding Digital Eye Strain (DES). This study aimed to assess the prevalence, symptom profile, and risk factors of DES among Indonesian medical students. Methods: A cross-sectional study was conducted among 356 medical students using the validated Computer Vision Syndrome Questionnaire (CVS-Q). Data on demographic characteristics, ocular history, digital device usage habits, and DES symptoms were collected. Bivariate and multivariate logistic regression analyses were performed to identify factors associated with DES, with a significance level set at p < 0.05. Results: The prevalence of DES was 62.9%. Common symptoms included itchy eyes (76.8%), blurred vision (70.1%), and headaches (76.33%). Bivariate analysis revealed associations between DES and refractive errors (OR 1.889, p = 0.004), poor posture (OR 0.467, p = 0.001), and the use of more than two digital devices daily (OR 1.610, p = 0.030). Multivariate analysis identified refractive errors (OR 2.049, 95% CI: 1.300–3.227, p = 0.002), poor posture (OR 0.413, 95% CI: 0.258–0.663, p < 0.001), and the use of more than two devices (OR 1.879, 95% CI: 1.171–3.015, p = 0.009) as independent risk factors for DES. Conclusion: DES is highly prevalent among Indonesian medical students. Refractive errors, poor posture, and the concurrent use of multiple digital devices were significant risk factors. Vision screening, ergonomic education, and digital health awareness are recommended to reduce DES and support ocular health.
Mekanisme Sinergis Ekstrak Etanol Serai dan Slow Interval Training terhadap Leptin, MDA, dan Histologi Adiposit pada Obesitas: Narrative Review Raudhatul Jannah; Yetty Machrina; Dwi Rita Anggraini
Jurnal Ners Vol. 10 No. 2 (2026): APRIL 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i2.56975

Abstract

Abstrak Latar Belakang: Obesitas merupakan faktor risiko utama sindrom metabolik yang berhubungan erat dengan stres oksidatif, resistensi leptin, dan remodeling jaringan adiposa. Kombinasi terapi herbal—khususnya ekstrak etanol serai (Cymbopogon citratus)—dan latihan fisik terstruktur berpotensi mengatasi disregulasi metabolik tersebut secara sinergis. Namun, bukti ilmiah mengenai mekanisme biologis kombinasi keduanya masih sangat terbatas. Tujuan: Review ini bertujuan menganalisis secara kritis jalur mekanistik efek kombinasi ekstrak etanol C. citratus dan slow interval training terhadap kadar serum leptin, kadar MDA, dan gambaran histologi sel adiposit pada model obesitas. Metode: Narrative review sistematis terhadap 28 artikel dari database Scopus, PubMed, ScienceDirect, dan Google Scholar (2020–2025), menggunakan kata kunci terstruktur dan kriteria inklusi–eksklusi ketat. Hasil dan Pembahasan: C. citratus mengandung senyawa bioaktif (citral, geraniol, limonene) yang terbukti menghambat peroksidasi lipid, menurunkan ekspresi TNF-α dan IL-6, serta memodulasi jalur PPARγ-adipogenesis. Slow interval training pada intensitas 50–70% HRmax mengaktifkan jalur AMPK-PGC1α, meningkatkan lipolisis, dan memperbaiki sensitivitas reseptor leptin (LepRb) melalui regulasi SOCS3. Secara sinergis, kombinasi keduanya diduga bekerja melalui reduksi stres oksidatif → normalisasi sinyal JAK2/STAT3 → pemulihan sensitivitas leptin → remodeling histomorfometri adiposit. Kesimpulan: Kombinasi C. citratus dan slow interval training memiliki potensi sinergis yang secara mekanistik dapat menurunkan MDA, memulihkan sensitivitas leptin, dan memperbaiki morfologi adiposit pada kondisi obesitas Kata Kunci: Cymbopogon citratus; leptin; malondialdehyde; slow interval training; adiposit; obesitas; stres oksidatif
Co-Authors Aditya Candra Aditya Candra Anggraini, Dwi Rita Ardinata, Dedi - Ashri Yudhistira Aznan Lelo Daulay, Milahayati Dedi Ardinata dharma Lindarto, dharma Diningrat, Diky Setya Eka Roina Megawati ELMAN BOY Gema Nazri Yanni Gema Nazri Yanni Gusbakti Rusip Gusbakti Rusip Harahap, Armansyah Maulana Harahap, Juliandi Koswara, Jocelyn Krishna Moorthi, Priya Darshini Laksmi, Lidya Imelda Lewis, Edwin - Lubis, Mahrani Maya Savira Mentari, Cindy Novita Sari Harahap Nuraiza Meutia Nurul Amalia Sofyan Pratiwi, Lisa Nabila Priawan, Indra Purba, Ambrocious Qori An-Nabil, Muhammad Rahmi Rahmi Rambe, Andrina Y.M Raudhatul Jannah Rina Amelia Ririe Fachrina Malisie Rusdiana Rusdiana Santi Syafril, Santi Selly Azmeila Sembiring, Rosita Juwita Siahaan, Sulyaprilawati Battri Sihombing, Rocky Charles Andreas Siregar, Kamal Basri Sri Sumartiningsih Syafruddin Ilyas Tarigan, Amira Permatasari Tri Widyawati, Tri Ulya, Ulfatul Wongso, Venessa Yamamoto, Zulham Yaznil, Muhammad Rizki Yunita Sari Pane Yusni Yusni Zega, Elwande Hagasaro