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Formulasi and Evaluasi Stabilitas Fisik Suspensi Ubi Cilembu (Ipomea batatas L.) dengan Suspending Agent CMC Na dan PGS Sebagai Antihiperkolesterol Fitriani, Yeyen Nor; INHS, Cikra; Yuliati, Ninis; Aryantini, Dyah
Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Vol. 2 No. 1 (2015)
Publisher : Faculty of Pharmacy, Widya Mandala Surabaya Catholic University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jfst.v2i1.699

Abstract

Drug which has small solubility in water is one of the problems that cause instability of pharmaceutical preparations. One drug practically insoluble in water is cilembu (Ipomoea batatas L.). So cilembu (Ipomoea batatas L.) made in form of suspension in order to produce stable preparations in liquid form. Making of the suspension cannot be separated from the suspending agent. CMC Na (Carboxymethylcellulose Sodium) and PGS (pulvis gummosus) is suspending agent which have been studied to produce a stable suspension. Accordingly, this study was conducted to know the suspension evaluation stability cilembu (Ipomoea batatas L.) with a suspending agent CMC Na and PGS as antihypercholesterol. Method of manufacture is dispersion method. Evaluation of physical stability test was conducted on the organoleptic, homogeneity, pH, density, viscosity, sedimentation volume, and redispersion. Data were analyzed with repeated measures and shelflife. Evaluation of physical stability the suspension cilembu with a suspending agent CMC Na and PGS on observations organoleptic, homogeneity, density and redispersion showed no difference, while the pH, viscosity and sedimentation volume were not significant differences (p< 0.05) during 30 days of storage.
Profil Kromatogram Senyawa Penangkap Radikal DPPH dari Ekstrak Kaempferia rotunda Berdasarkan Perbedaan Metode Ekstraksi Aryantini, Dyah; Lailiyah, Munifatul; Hardini, Pri
Jurnal Sintesis: Penelitian Sains, Terapan dan Analisisnya Vol 6 No 2 (2025): Desember 2025
Publisher : Fakultas Sains, Teknologi, dan Analsisi Institut ilmu Kesehatan Bhakti Wiyata

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56399/jst.v6i2.348

Abstract

Tanaman Kaempferia rotunda merupakan tanaman obat yang secara empiris bermanfaat untuk mengobati batuk, diare, menyembuhkan luka, menurunkan demam bahkan untuk mengobati kanker. K. rotunda mengandung senyawa seperti flavonoid, fenol, Crotepoxide, Pinostrobin, saponin, tanin, dan minyak atsiri. Penelitian ini bertujuan untuk mengetahui profil kromatogram dari analisis Kromatografi Lapis Tipis (KLT) senyawa yang terdapat dalam ekstrak K. rotunda menggunakan dua metode ekstraksi yang berbeda yakni maserasi dan reflux terhadap radikal DPPH secara kualitatif. Hasil rendemen ekstrak maserasi dan refluk sebesar 8,58% dan 3,98% b/b, perbedaan ini terjadi karena durasi ekstraksi serta sifat yang terlarut mungkin bersifat termolabil. Hasil skrining menunjukkan adanya senyawa flavonoid, saponin dan alkaloid pada hasil ekstrak maserasi dan refluk. Hasil identifikasi KLT diperoleh hasil positif flavonoid, fenol, saponin, alkaloid serta terdapat aktivitas penangkap radikal DPPH pada hasil ekstrak maserasi dan refluk yang ditunjukkan dengan adanya spot berwarna kuning pada rentang Rf 0,2-0,8 yang menandakan peredaman terhadap radikal DPPH.
Edukasi Pemanfaatan Herbal (Daun Sirih, Cengkeh dan Kayu Manis) Sebagai Obat Kumur Untuk Mencegah Caries Gigi Di Kawasan Gelandangan Chow Kit Malaysia Aryantini, Dyah; Shofi, Muh.; Agustina, Lia; Yuliati, Ninis; Fauzi Sabban, Indra
Bersama : Jurnal Pengabdian Kepada Masyarakat Vol. 4 No. 1 (2026): Bersama: Jurnal Pengabdian Kepada Masyarakat
Publisher : Fakultas Pertania Universitas Muara Bungo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36355/bsm.v4i1.67

Abstract

The Chow Kit settlement in Kuala Lumpur, Malaysia, is characterized by a population of homeless and low-to-no-income residents. As such, this area frequently becomes a focus for social institutions implementing Community Service Responsibility (CSR) programs, particularly in the health domain. This CSR initiative represents a collaborative effort between USIM Malaysia (Faculty of Dentistry) and the Faculty of Pharmacy (IIK Bhakti Wiyata Kediri, Indonesia), focusing on educational interventions to prevent and reduce dental caries through the use of herbal mouthwash formulations. Dental caries has emerged as a prevalent oral health concern with a significant impact on overall health. The condition originates from the formation of Streptococcus mutans bacterial biofilms, which are typically exacerbated by excessive consumption of sugary foods and tobacco use. The community service methodology employed participatory counseling and educational approaches, utilizing purposive sampling techniques. Evaluation of the program demonstrated enhanced comprehension among the 22 participants, with mean pre-test scores of 57.39 improving to 79.09 post-intervention, reflecting a 21.7% increase. While some participants maintained baseline scores, 86.5% of attendees (19 individuals) achieved improvements exceeding 20 points. Sustainable monitoring and evaluation mechanisms remain essential, given that the participant cohort primarily consists of homeless individuals whose transient living circumstances often preclude consistent maintenance of personal oral hygiene practices.