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Journal : Jurnal Veteriner

Aktivitas Antibakteri Ekstrak Daun Sirsak (Annona muricata L.) Terhadap Pertumbuhan Bakteri Pseudomonas aeruginosa Secara In Vitro (ANTIBACTERIAL ACTIVITY OF SOURSOP (ANNONA MURICATA) LEAF EXTRACT ON GROWTH OF BACTERIA PSEUDOMONAS AERUGINOSA IN VITRO) Faisal Fikri; Imas Hapsari Rahmaningtyas; Ragil Angga Prastiya; Muhammad Thohawi Elziyad Purnama
Jurnal Veteriner Vol 20 No 3 (2019)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (121.707 KB) | DOI: 10.19087/jveteriner.2019.20.3.384

Abstract

The aim of this study was to measure antibacterial activity of soursop leaf extract (Annona muricata L.) on bacterial growth inhibition of Pseudomonas aeruginosa by diffuse disc method. The result of the inhibition zone was analyzed using Analysis of Variance and followed using Duncan test, to show highly significantly different (p<0.01). The inhibition number of negative control (C-) was 0.00e±0.00 and the positive control (C+) was 31.31a±0.57. The result of concentration 1 (T1) was 14.49b±4.96; concentration 2 (T2) 8.98c±1.29; concentration 3 (T3) 5.84cd±1.85; concentration 4 (T4) 5.56cd±1.58; concentration 5 (T5) 2.85de±0.28; concentration 6 (T6) 2.98de±0.53; concentration 7 (T7) 2.82de±1.59; concentration 8 (T8) 2.41de±1.10; concentration 9 (T9) 2.20de±0.34; concentration 10 (T10) 1.10e±0.19; and concentration 11 (T11) 0.00e±0.00. The increase of soursop leaf extract concentration showed high inhibition diameter of bacterial growth. It concluded that soursop leaf extract have an antibacterial activity to inhibit P. aeruginosa growth with Minimal Inhibitory Concentration (MIC) 125 ppm.
Ekstrak Etanol Kulit Buah Naga Menurunkan Indikasi Neoplasia Mammae Tikus Putih Berdasarkan Histopatologi dan Inhibitor Siklooksigenase-2 Muhammad Thohawi Elziyad Purnama; Ragil Angga Prastiya; Faisal Fikri; Amung Logam Saputro; Bodhi Agustono
Jurnal Veteriner Vol 19 No 1 (2018)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (192.173 KB) | DOI: 10.19087/jveteriner.2018.19.1.23

Abstract

Cancer caused uncontrolled cell proliferation and triggered by changes on cell information that regulate growth function. Each cell has different potential so many cancer prevalence such as endometrial cancer, lymph node cancer, lung cancer, skin and mammary gland cancer. The aims of this study were to assess the potential of dragon fruit skin ethanolic extract on white rats (Rattus norvegicus) exposed 7,12- Dimethylbenz(á)antrasena (DMBA) on mammary gland based on histopathological features and cyclooxygenase-2 (Cox-2) intensity. This study were used 20 of rats randomly divided into five group and each groups consisted of four rats, i.e: K+ weren’t treated DMBA and extract; K- were treated with DMBA; P1 were treated with DMBA and extract 10 mg/kg BW; P2 were treated with DMBA and extract 15 mg/kg BW; P3 were treated with DMBA and extract 20 mg/kg BW. The DMBA was given by intra dermal injection during twice a week for five weeks and the extracts with gastric tube everyday till 14 days. The data was analyzed by Anova test and continued with Duncan test. The result showed that the histopathological features were decrease significantly on P3. The variables of Cox-2 intensity were decrease significantly on P1, P2 and P3. Conclusion of this study was ethanol extract of dragon fruit skin can decrease neoplastic indication of mammary gland on white rats (R. norvegicus) based on histopathological features and Cox-2 inhibitors.
Aktivitas Superoxide Dismutase pada Serum Darah Babi Landrace yang Disembelih dengan Metode Electrical Stunning Shabrina Fauzia Prayoga; Kuncoro Puguh Santoso; Nove Hidajati; Faisal Fikri; Maya Nurwartanti Yunita; Muhammad Thohawi Elziyad Purnama
Jurnal Veteriner Vol 22 No 2 (2021)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (147.263 KB) | DOI: 10.19087/jveteriner.2021.22.2.168

Abstract

Tujuan penelitian ini untuk menentukan aktivitas Superoxide Dismutase (SOD) pada babi Landrace yang disembelih dengan metode stunning dan non-stunning. Sebanyak 18 ekor babi Landrace jantan dewasa yang telah dikebiri dengan masing-masing bobot 115±20 kg dibagi menjadi dua kelompok, yakni stunning dan non-stunning dengan pengujian serum pada pre dan post treatment. Electrical stunning dilakukan dengan aliran listrik pada dua elektroda sebesar 220 volt dan 1,3 ampere. Sampel darah diambil sebanyak 3 mL, kemudian diuji aktivitas SODnya.. Hasil aktivitas SOD dianalisis dengan uji T berpasangan untuk membandingkan aktivitas SOD serum antara stunning dan non-stunning pada fase pre dan post treatment. Hasil stunning menunjukkan penurunan signifikan (p<0,05) aktivitas SOD sebesar 56,12±54,47 dibandingkan non-stunning sebesar 137,84±66,63. Aktivitas SOD yang rendah tampak signifikan (p<0,05) juga pada pre-treatment dibandingkan dengan post-treatment. Dapat disimpulkan bahwa penyembelihan dengan metode electrical stunning menurunkan aktivitas SOD pada serum babi Landrace.