Claim Missing Document
Check
Articles

Found 23 Documents
Search

CPOB 2024: Kunci Sukses Produksi Obat yang Aman dan Berkualitas Wibowo, Teguh Setiawan; Rahmawati, Riana Putri
Jurnal Pengabdian West Science Vol 4 No 04 (2025): Jurnal Pengabdian West Science
Publisher : Westscience Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58812/jpws.v4i04.2112

Abstract

Penerapan Cara Pembuatan Obat yang Baik (CPOB) 2024 menjadi faktor utama dalam memastikan produksi obat yang aman, bermutu, dan berkhasiat. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pemahaman dan keterampilan para pelaku usaha di industri farmasi dalam mengimplementasikan standar terbaru CPOB 2024. Metode yang digunakan meliputi sosialisasi, pelatihan praktis, dan pendampingan teknis kepada peserta program profesi apoteker Universitas Muhammadiyah Kudus angkatan 11 dalam menerapkan prinsip-prinsip CPOB, mulai dari kontrol bahan baku, proses produksi, hingga pengawasan mutu. Hasil kegiatan menunjukkan peningkatan pemahaman peserta terhadap regulasi dan penerapan CPOB, serta kesadaran akan pentingnya sistem dokumentasi dan pengendalian proses produksi untuk menjamin keamanan dan kualitas produk. Dengan adanya pelatihan ini, diharapkan para pelaku industri farmasi dapat lebih siap dalam memenuhi standar regulasi serta meningkatkan daya saing produk obat bahan alam di pasar nasional maupun internasional.
Peningkatan Pengetahuan Swamedikasi untuk Anak “Bunda Kenal Obat, Anak Sehat” Muslim, Ahmad Suriyadi; Rahmawati, Riana Putri; Kurniawati, Pratiwi; Malihatin, Putri Dewi; Setianingsih, Indah Wahyu
JOURNAL OF PHILANTHROPY: The Journal of Community Service Vol. 3 No. 1 (2025): Journal of Philanthropy, January 2025
Publisher : Samodra Ilmu: Lembaga Penelitian, Penerbitan, dan Jurnal Ilmiah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58353/jop.v3i1.249

Abstract

A child can be defined as a human being under the age of 18, including an unborn child. All aspects of a child's needs are heavily dependent on their parents, particularly their mother. This includes basic needs such as nutrition, affection during growth and development stages, and guidance on parenting, all of which are primarily provided by the mother. During the growth and development stages, children are vulnerable to various illnesses, including fever, cough, cold, diarrhea, itchiness, and rashes. As a result, mothers need to be able to provide self-medication or swamedikasi. This community service program aims to enhance the knowledge and understanding of mothers, specifically those of KB Aisyiah 1 Kudus, in providing self-medication for their children. The program consists of several stages, including obtaining permits, distributing pre-test questionnaires, presenting materials, and concluding with post-test questionnaires. The program's evaluation is based on the analysis of the pre-test and post-test questionnaires. The community service program lasted for approximately four days, with participants comprising mothers of KB Aisyiah 1 Kudus students. The prevalence of participants' ages ranged from 25-30 years, with most having more than one child and being housewives (seven participants). The program resulted in a significant increase in the average pre-test and post-test scores, with a 57.14% improvement. This indicates that the program has successfully enhanced the mothers' knowledge and understanding of self-medication.
Testing the Effectiveness of Basil Leaf Essential Oil (Ocimum basilicum L) against Aedes Aegypti Mosquitoes in Aromatherapy Candles Rahayu, Santi Dwi; Rahmawati, Riana Putri; Arif, Fahrudin
Advances in Healthcare Research Vol. 3 No. 2 (2025): March - August
Publisher : Yayasan Pendidikan Bukhari Dwi Muslim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60079/ahr.v3i2.541

Abstract

Purpose: This study aims to formulate basil leaf essential oil (Ocimum basilicum L.) as an active ingredient against Aedes aegypti mosquitoes in the form of aromatherapy wax that can be applied by inhalation. Research Method: This study is a laboratory experimental study. Essential oil from basil leaves was obtained through steam distillation, while the wax preparation was made using the melting method. The aromatherapy wax formulation consisted of five groups, namely positive control, negative control, formulation I (2%), formulation II (4%), and formulation III (6%). Each formulation was tested through a series of physical property tests, including organoleptic tests (color, odor, and shape), burning time test, melting point test, and effectiveness test as an insect repellent against Aedes aegypti. Data analysis was performed using a one-way ANOVA statistical test and followed by a Tukey Post Hoc test. Results and Discussion: The results showed that aromatherapy candles containing basil essential oil had varying effectiveness against mosquito mortality. Formulations with higher concentrations (4% and 6%) provided the best results in physical testing and biological effectiveness compared to other formulations and controls. Implications: This study supports the development of natural-based aromatherapy candles as a safe, effective, and environmentally friendly alternative insecticide for controlling Aedes aegypti mosquitoes in domestic environments.
Formulation and Antibacterial Activity Testing of Face Mist Made from Red Betel Leaf (Piper Crocatum Ruiz and Pav.) Ethanol Extract Against Propionibacterium Acnes Anggraeni, Ira; Rahmawati, Riana Putri; Besan, Emma Jayanti
Advances in Healthcare Research Vol. 3 No. 2 (2025): March - August
Publisher : Yayasan Pendidikan Bukhari Dwi Muslim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60079/ahr.v3i2.571

Abstract

Purpose: This study aimed to formulate and evaluate the antibacterial activity of face mist containing ethanol extract of red betel leaf (Piper crocatum Ruiz & Pav.) against Propionibacterium acnes, with the hypothesis that higher extract concentrations enhance antibacterial efficacy. Research Method: A quantitative experimental design was conducted using three formulations with extract concentrations of 15%, 25%, and 35%, alongside positive (clindamycin 300 mg) and negative (base face mist) controls. Samples were obtained from Kayen Village, Pati Regency, Indonesia. Physical evaluations included organoleptic, homogeneity, pH, and spreadability tests, while antibacterial activity was assessed using the disc diffusion method. Data were analyzed with Shapiro–Wilk, Levene’s, One-Way ANOVA, and LSD Post Hoc tests. Results and Discussion: All formulations met physical quality standards. Antibacterial testing showed inhibition zones of 7.57 mm (moderate) for 15%, 10.67 mm (strong) for 25%, and 13.47 mm (strong) for 35%, with higher concentrations producing greater inhibition. Positive control exhibited a 37.60 mm (very strong) inhibition zone, while the negative control showed no activity. Implications: Red betel leaf extract demonstrates potential as a natural antibacterial ingredient in acne treatment formulations. The 35% concentration was optimal but still less effective than clindamycin. Future research should focus on optimizing formulation stability, enhancing sensory appeal, and exploring synergistic combinations to improve efficacy.
Pola Pengobatan Pasien Hipertensi di Puskesmas X Kabupaten Kudus Muslim, Ahmad Suriyadi; Rahmawati, Riana Putri; Sugiarti, Retno; Sari, Fatika; Amalia, Linda
Jurnal Indonesia Sehat Vol. 3 No. 3 (2024): JURINSE: Desember 2024
Publisher : SAMODRA ILMU: Lembaga Penelitian, Penerbitan, dan Jurnal Ilmiah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58353/jurinse.v3i3.251

Abstract

Background: According to the WHO, hypertension is a degenerative disease suffered by the majority of the world's population. Meanwhile, in Indonesia itself, the number of people suffering from hypertension increased by 25.8%. If left untreated, hypertension can cause various other diseases such as stroke, heart attack, and diabetes mellitus. Method: This study aims to determine the treatment patterns of hypertensive patients at Puskesmas Rejosari, Kudus Regency. This type of research is a non-experimental descriptive study using a retrospective approach with patient data from July to September 2024. Research Results: The results of the study show that the prevalence of anti-hypertensive medication use in the CCBs group with amlodipine was 50%, the ACE Inhibitor group with captopril was 20%, the use of Hydrochlorothiazide (HCT) was 10%, furosemide was 5%, and the use of combination therapy was 15%. Conclusion: The antihypertensive medication utilization pattern among hypertensive patients at the Puskesmas primarily involves the use of CCB (Amlodipine) as the first-line treatment. The effective and safe use of antihypertensive medications can contribute to blood pressure control and the prevention of hypertension-related complications.
Rahasia Sehat dari Dapur Tradisi: Workshop Pembuatan Minyak Gosok untuk Kesehatan Alami Wibowo, Teguh Setiawan; Rahmawati, Riana Putri; Wulandari, Ninuk; Aguswina, Melany Eka; Putri Susanti, Dina Eka
Jurnal Pengabdian West Science Vol 4 No 09 (2025): Jurnal Pengabdian West Science
Publisher : Westscience Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58812/jpws.v4i09.2708

Abstract

Minyak gosok tradisional merupakan salah satu warisan kearifan lokal yang telah digunakan secara turun-temurun oleh masyarakat Indonesia untuk menjaga kesehatan dan mengatasi berbagai keluhan ringan, seperti pegal linu, nyeri otot, serta kelelahan fisik. Di tengah pesatnya perkembangan teknologi kesehatan dan dominasi obat-obatan modern, praktik tradisional ini tetap bertahan karena dinilai lebih aman, alami, dan terjangkau. Artikel ini membahas pelaksanaan workshop pembuatan minyak gosok tradisional yang bertujuan meningkatkan pemahaman masyarakat mengenai manfaat tanaman obat, teknik pembuatan minyak gosok yang higienis, serta potensi pemanfaatannya untuk kesehatan keluarga maupun peluang usaha berbasis herbal. Kegiatan ini menggunakan pendekatan partisipatif dengan memadukan penjelasan teoritis dan praktik langsung, sehingga peserta memperoleh keterampilan yang aplikatif dan berorientasi pada pemberdayaan masyarakat. Hasil workshop menunjukkan adanya antusiasme tinggi dari peserta dalam menggali potensi kearifan lokal, sekaligus kesadaran untuk mengintegrasikan pengetahuan tradisional dengan prinsip ilmiah. Artikel ini diharapkan dapat memberikan kontribusi dalam pelestarian budaya, promosi kesehatan alami, dan pengembangan ekonomi kreatif berbasis tanaman obat.
HUBUNGAN ANTARA KETEPATAN DOSIS ANTIBIOTIKA DENGAN LAMA RAWAT INAP PASIEN DENGAN GANGGUAN NAFAS DI RUANG NICU (Neonatal Intensive Care Unit) RSUD R.A. KARTINI KABUPATEN JEPARA PERIODE TAHUN 2024 Septiani, Hanim Ayun; Rahmawati, Riana Putri; Sukoharjanti, Bintari Tri
Parapemikir : Jurnal Ilmiah Farmasi Vol 14, No 3 (2025): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v14i3.9517

Abstract

Gangguan nafas pada neonatus merupakan salah satu penyebab utama perawatan intensif di ruang NICU. Infeksi bakteri menjadi faktor pemicu yang sering ditemukan, sehingga penggunaan antibiotik menjadi terapi utama. Ketepatan dosis antibiotik sangat penting untuk memastikan efektivitas terapi dan mencegah resistensi, serta mempercepat proses penyembuhan. Ketidaktepatan dalam pemberian dosis dapat memperpanjang durasi infeksi dan berdampak pada lama rawat inap pasien. Penelitian ini bertujuan untuk mengetahui hubungan antara ketepatan dosis antibiotika dengan lama rawat inap pasien neonatus dengan gangguan nafas di ruang NICU RSUD R.A. Kartini Kabupaten Jepara. Penelitian ini menggunakan metode kuantitatif dengan pendekatan cohort retrospektif, yaitu melalui penelusuran dari rekam medis pasien yang dirawat di ruang NICU RSUD R.A. Kartini Kabupaten Jepara pada periode Januari-Desember 2024. Data diperoleh melalui telaah rekam medis pasien, kemudian dianalisis menggunakan uji univariat dan bivariat uji  menggunakan uji chi-square untuk melihat hubungan antar variabel. Hasil penelitian pada 101 responden dilakukan uji chi square dan mendapat nilai            P-value sebesar 0.579 ( p = 0.05), maka Ho diterima dan Ha ditolak sehingga dapat disimpulkan bahwa tidak ada hubungan antara ketepatan dosis antibiotika dengan lama rawat inap pasien dengan gangguan nafas di ruang NICU (Neonatal Intensive Care Unit) RSUD R.A. Kartini Kabupaten Jepara.
Formulation and Efficacy Test of Antistress Aromatherapy Candle with Jasmine Essential Oil (Jasminum sambac L) on Mice (Mus musculus) Febrianti, Noor Alfina; Rahmawati, Riana Putri; Arif, Fahrudin
Advances in Healthcare Research Vol. 3 No. 2 (2025): March - August
Publisher : Yayasan Pendidikan Bukhari Dwi Muslim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60079/ahr.v3i2.521

Abstract

Purpose: Aromatherapy is a non-pharmacological healing method that uses essential oils as therapeutic agents. Jasmine flowers (Jasminum sambac L.) contain active compounds such as linalool, benzyl acetate, methyl salicylate, cis-jasmone, nerolidol, and indole that have potential applications in stress management. This study aims to investigate the antistress efficacy of aromatherapy candles made from jasmine essential oil on mice (Mus musculus). Research Method: This study employed a laboratory experiment with a post-test-only control group design. A total of 25 male mice were divided into five groups, each consisting of five mice. The treatment groups were exposed to aromatherapy candles with essential oil concentrations of 2%, 4%, and 6%, while the control groups included a negative control and a positive control. Stress induction was performed using the Tail Suspension Test (TST), and effectiveness was assessed through immobility time parameters. Data analysis was conducted using a One-Way ANOVA test. Results and Discussion: The results indicate that the wax formula with a concentration of 6% has the best physical characteristics and provides the fastest relaxation effect. The ANOVA test reveals a significant difference between groups (p < 0.05), indicating a significant effect of aromatherapy wax on stress reduction in mice. Implications: This study reinforces the potential of jasmine essential oil-based aromatherapy candles as an alternative therapy for stress management, while also supporting the development of safe and effective, naturally based health products.
Formulation and Efficacy Test of Antistress Aromatherapy Candles Containing Peppermint Leaf Essential Oil (Mentha Piperita L) and Clove Leaf Essential Oil (Syzygium Aromaticum L) on Mice (Mus Musculus) Nazilla, Khunut; Rahmawati, Riana Putri; Sukoharjanti, Bintari Tri
Advances in Healthcare Research Vol. 3 No. 2 (2025): March - August
Publisher : Yayasan Pendidikan Bukhari Dwi Muslim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60079/ahr.v3i2.523

Abstract

Purpose: This study aims to determine the effectiveness of aromatherapy candles containing peppermint (Mentha piperita L.) and clove (Syzygium aromaticum L.) essential oils at concentrations of 3%, 5%, and 7% on mice. Research Method: This study employed a laboratory experimental method with a post-test-only control group design. The formula used in this study was a combination of peppermint and clove with concentrations FII (2%:1%), FIII (3%:2%), and FIV (4%:3%), as well as negative and positive controls (lavender). The evaluation was conducted on physical tests of the candles, including organoleptic tests, burn time tests, and melting point tests. The antistress effectiveness testing was divided into five groups, each consisting of 5 mice. The first treatment involved the Tail Suspension Test to induce stress in the mice. Subsequently, the mice were exposed to aromatherapy candles, and the Forced Swimming Test was conducted. The test results were analyzed using the One-Way ANOVA test. Results and Discussion: All aromatherapy candle formulas met the physical evaluation test requirements. Formulas FII and FIII demonstrated antistress efficacy with a significance value of less than 0.05. Implications: These results indicate that the combination of peppermint leaf essential oil and clove leaf essential oil has potential as an active ingredient in anti-stress aromatherapy candles. Further research is needed to support its effectiveness on a broader scale.
EFEKTIVITAS BIOINSEKTISIDA EKSTRAK ETANOL BAWANG PUTIH (Allium sativum) TERHADAP MORTALITAS KECOA AMERIKA (Periplenata americana) Rahmawati, Riana Putri; Etikasari, Ria; Setyaningrum, Intansari; Wilisa, Oni Yulianta; Andjarwati, Fitri Nur
Prosiding University Research Colloquium Proceeding of The 13th University Research Colloquium 2021: Kesehatan dan MIPA
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Bioinsektisida alami merupakan upaya pemanfaatan tanaman herbal sebagai pestisida alami guna membasmi serangga atau hama yang merusak tanaman ataupun merugikan manusia, hal ini dilakukan atas dasar pertimbangan pemanfaatan potensi flora alam yang banyak di temui di sekitar manusia. Tanaman di Indonesia banyak yang berkhasiat sebagai insektisida alami diantaranya bawang putih. Pemanfaatan bawang putih (Allium sativum) dapat digunakan sebagai bioinsektisida alami yang memiliki kandungan flavonoid dan zat alicin. Kecoa merupakan organisme yang seringkali mengganggu kenyamanan dengan meninggalkan bau yang tidak sedap, menyebarkan berbagai patogen penyakit, dan menimbulkan alergi. Penelitian ini bertujuan untuk mengetahui aktivitas bioinsektisida ekstrak bawang putih (Allium sativum) terhadap mortalitas kecoa amerika (Periplaneta americana). Penelitian eksperimental laboratorium dengan melakukan pembuatan bioinsektisida ekstrak etanol bawang putih (Allium sativum) menggunakan metode maserasi. Ektrak kental yang didapat kemudian dibuat 5 kelompok perlakuan yaitu kelompok konsentrasi 1%,5%,10%,20%,30%, kontrol positif pestisida merk “X” dan kontrol negatif dengan aquadestilata. Pengamatan dilakukan pada jam ke-1, 3, 6, 12, 24, 48 dan 72. Parameter yang diamati adalah jumlah mortalitisa kecoa. Hasil penelitian ini menunjukkan mortalitas tertinggi pada konsentrasi 30% sebanyak 83,33% yaitu dapat membunuh 15 kecoa dengan 3 kali replikasi dan mortalitas terendah pada konsentrasi 1% sebanyak 5,56 % dapat membunuh 1 kecoa dengan 3 kali replikasi. Hal ini menunjukkan bahwa semakin tinggi konsentrasi ekstrak yang diberikan maka semakin tinggi angka kematiannya.