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All Journal CAKRA KIMIA (Indonesian E-Journal of Applied Chemistry) Jurnal Veteriner JURNAL PETERNAKAN Indonesian Journal of Pharmaceutical Science and Technology Pharmascience Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) As-syifaa Jurnal Farmasi Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal farmasi UIN Alauddin Makassar Jurnal Agrisistem Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Parapemikir Jurnal Ilmiah Farmasi Kartika : Jurnal Ilmiah Farmasi
Abdul Wahid Jamaluddin
Universitas Hasanuddin
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Electrical & Electronics Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Physics Public Health Social Sciences Veterinary

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Perbandingan Pemberian Madu Lokal Bunga Cengkeh (Syzygium aromaticum) dan Madu Impor Bunga Manuka (Leptospermum scoparium) Secara Topikal Terhadap Penyembuhan Luka Sayat Pada Mencit Putih (Mus musculus) Nikita Tenritojang Mustafa; Dini Kurnia Ikliptikawati; Abdul Wahid Jamaluddin
Jurnal Pharmascience Vol 6, No 2 (2019): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v6i2.7347

Abstract

ABSTRAK Luka merupakan trauma fisik mengakibatkan kulit terbuka. Luka merupakan jalur masuk bagi mikroorganisme dari luar penyebab infeksi. Dahulu madu dimanfaatkan untuk mengobati luka bakar dan luka sayat. Madu memiliki keunggulan yakni memiliki hidrogen peroksida, eugenol dan methylglyoxal yang merupakan antibiotik yang unggul. Penelitian ini dilakukan dengan uji ekperimental. Hewan coba dibagi dalam 4 kelompok. Setiap kelompok diberikan perlakukan antara lain: dengan pemberian madu lokal, madu impor, dan salep povidone iodine (kontrol positif), dan kelompok kontrol negatif tanpa perlakuan. Dilanjutkan pemantauan dan pencatatan untuk proses penyembuhan tiap kelompok. Hal ini diukur dengan indikator antara lain: luas luka, kelembaban luka, warna, serta perubahan keropeng. Pada penelitian ini ditemukan bahwa dengan pemberian madu mempercepat proses penyembuhan luka dibandingkan dengan pemberian air dan povidone iodine (p<0,05). Selain itu ditemukan madu lokal memberikan efek penyembuhan luka yang lebih cepat dibandingkan madu impor. Pemberian madu memberikan efek yang lebih baik terhadap penyembuhan luka. Dibandingkan dengan pemberian salep Povidone iodine dan tanpa perlakuan.Kata kunci : Madu Bunga Cengkeh, Madu Bunga Manuka, Waktu penyebuhan, Warna Luka, Kelembaban. ABSTRACT Wound is a physical trauma causes discontinuity, Leads physiological dysfunction. Wound is an entry point for microorganisms from outside as source of infection. In the past, honey was used to treat burns and cuts. Honey is a natural ingredient as a moist wound-dressings. Besides that, honey contain hydrogen peroxide, eugenol, and methylglyoxal which is a superior antibiotic. This research was carried out by experimental test. The experimental animals were divided into 4 groups, each group consisted of 6 animals. Each group is treated, among others; by giving local honey, imported honey, povidone iodine (positive control), and negative control group without a treatment. Continued monitoring and recording for the healing process of each group. Statistical analysis is performed by calculation of frequency distribution and Independent-t, Anova, and regression analysis to determine the relationship between each variable. Statistical test results are significant if the value of p <0.05. This research found that addition of honeyaccelerated the wound healing process compared to the administration of water and povidone iodine (p <0.05). This is measured by indicators including; wide wounds, moisture wounds, colour change, and scab changes. By giving honey the perfect wound healing process begins on the 11th day until the 13th day. Besides that, local honey is found to provide healing effects that are faster than imported honey. Giving honey provides a better effect on wound healing. compared with Povidone iodine and without a treatment Keywords: Clove Flower Honey, Manuka Flower Honey, Time of Wasting, Colour of Wound, Moisture
Detection of Proteus mirabilis as foodborne disease bacteria in carcass of broiler chickens (Gallus domesticus) Abdul Wahid Jamaluddin; Lucia Muslimin; Muhammad Natsir Djide
Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) VOLUME 2 NO. 1, JANUARY 2018
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jrvi.v2i1.4386

Abstract

Poor hygiene of traditional market often resulted in bacterial contamination of chicken meat including Proteus mirabilis which is also serve as a foodborne disease in human. Proteus mirabilis is pathogenic to humans because it can produces the urease which results in urinary tract infections (UTI). This research aimed to determine the presence of Proteus mirabilis bacteria in chicken meat sold in some traditional markets in the city of Makassar. The samples used in this study (24 samples) were obtained from 6 Traditional Markets in Makassar. Colony observation, Gram staining and biochemical test were used to identify Proteus mirabilis in the chicken carcass. Positive samples were confirmed by Polymerase Chain Reaction (PCR). The result of this study revealed that 12.5% (3/24) were positively contaminated with Proteus mirabilis. The conclusion of this study was that chicken meat sold in the traditional market of Makassar has already been contaminated with Proteus mirabilis
Combination Effect of Golden Snail Powder and Fermented Coconut Cake on Quality of Duck Eggs Nurmauliah Syaharuddin; Rasdyanah Rasdyanah; Dwi Kesuma Sari; Waode Santa Monica; Abdul Wahid Jamaluddin
Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) VOLUME 3 No. 2, JULY 2019
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jrvi.v3i2.6627

Abstract

This study aims to determinate the effect of combination golden snail powder and fermented coconut cake on quality of duck eggs. We were using experimental feeds combination form golden snail powder and fermented coconut cake as raw material for livestock rearing for duck. This research was conducted in July - September 2018 in Mangkoso Village, Barru Regency and continued with sample testing at the Laboratory Animal Husbandry Faculty of Livestock Product Technology University of Hasanuddin. This study used 16 female duck who are 20 weeks old with four types of treatments consists of four replications of each treatment. The egg quality was carried out using a sample of 16 eggs from Ducks which was maintained and treated with different rations. The data obtained were analyzed using variance analysis with a Completely Randomized test for significant different results. The results of the combination of golden snail powder and fermented coconut cake on egg color, egg white index, egg yolk index, haugh unit (HU) value of egg units. All treatments (P1, P2, P3) gave effect to three parameters, namely eggshell quality, egg yolk index and egg yolk color, while the other three parameters namely egg weight, egg white index and Haugh Unit (HU) value did not differ significantly from negative controls. The best treatment was shown by treatment P3 which gave an effect on the heavier egg weight than other treatments, eggshell quality grade A, Egg White Index and Egg Yolk Index showed good quality and bright golden egg yolks. 
Effectiveness of Ginger Ointment (Zingiber officinale roscoe) on Incision Wound Healing in White Rats (Rattus norvegicus) Abdul Wahid Jamaluddin; Ayu Lestari; Wa Ode Santa Monica
Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) VOLUME 5 No. 1, JANUARY 2021
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jrvi.v5i1.13060

Abstract

Ginger (Zingiber officinale roscoe) is one of the most popular plants to be processed into herbal medicine. This plant contains active compounds in the form of gingerols, shogaols, flavonoids and saponins, which have anti-inflammatory, anti-tumor, antioxidant and antimicrobial effects. This study aims to determine the effectiveness of ginger extract ointment on incision wound healing time in white rats (Rattus norvegicus) by observing the percentage of wound healing and changes in wound morphology. This study used a laboratory experimental method using 24 white rats as test animals which were divided into four groups, namely two treatment groups (10% and 20% ginger extract ointment) and two control groups (one negative control group (no treatment) and one positive control group (Oxyfresh Soothing Pet Gel®)). The rats were anesthetized and shaved, then an incision was made on the dorsal part of the rat. The treatment was given twice a day for 14 days. The results showed that there were differences in the comparison of the percentage of wound area between the negative control group (without treatment), the positive control (Oxyfresh Soothing Pet Gel®), the treatment groups (ginger extract ointment 10% and 20%). The conclusion of the study was that the treatment group with 10% ginger extract ointment was more effective in accelerating the wound healing process. Keywords: Ginger extract,  Incision, wound healing, ointment, white rat.
Description of Neutrophil Cells of Giving Sugar and Honey in Incision Wound of Domestic Cat (Felis domestica) Muhammad Fadhil Shalih; Waode Santa Monica; Dwi Kesuma Sari; Abdul Wahid Jamaluddin
Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) VOLUME 5 No. 1, JANUARY 2021
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jrvi.v5i1.13598

Abstract

Neutrophils are one of the most abundant cells of the immune system and are very active during the wound healing process. This study aimed to determine the description and comparison of neutrophil cells after treated sugar and honey in the incision wounds of domestic cats (F. domestica). 15 samples were used with treatment for 14 days and the preparations were given topically. The treatment group consisted of 5 groups, namely Negative control group (NCG) with normal wound healing (without treatment), Positive control group (PCG) given Bioplacenton ointment, treatment group 1 (TG1) used sugar, treatment group 2 (TG2) used honey, Group Treatment 3 (TG3) used combination of sugar and honey. Skin samples were taken on the 4th, 9th, and 14th day of each group to make histopathology preparations and observation under a microscope by assessing the number of neutrophil cells with an indicator score of 0 - 5. Treatment Group 1 (TG1 ) used sugar shown the best decrease in the number of neutrophil cells with the development of the same healing process like as Treatment Group 3 (TG3) used a combination of sugar and honey, while Treatment Group 2 (TG2) used honey shown also a decrease in the number of neutrophil cells. The three treatment groups showed a better healing process than Negative control group (NCG) without treatment and showed almost equivalent results to the Positive control Group (PCG) used Bioplacenton ointment. Keyword: Histopathology, honey, neutrophil, sugar
UJI EFEK EKSTRAK DAUN JAMBU BIJI (Psidium guajava L.) TERHADAP BAKTERI Salmonella pullorum SECARA IN VITRO A. Ika H.A. Imran A.B; Abdul Wahid Jamaluddin; Sitti Arifah
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 3 No 2 (2018): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (308.133 KB) | DOI: 10.36387/jiis.v3i2.196

Abstract

Salmonella pullorum merupakan bakteri yang mempunyai hospes spesifik dan infeksius terhadap unggas, terutama pada anak ayam dan anak kalkun. Salah satu gejala klinis dari penyakit yang disebabkan oleh bakteri ini adalah diare. Untuk menangani masalah bakteri ini umumnya digunakan antibiotik, namun penggunaan yang berlebihan akan menyebabkan residu dan resistensi antibiotik. Untuk menghindari hal tersebut dibutuhkan alternatif pengobatan. Daun jambu biji dikenal sebagai obat tradisional diare. Penelitian ini bertujuan untuk mengetahui efek ekstrak daun jambu biji terhadap bakteri Salmonella pullorum secara in vitro. Penelitian ini menggunakan 6 perlakuan dengan 3 pengulangan diantaranya menggunakan disk tetrasiklin sebagai kontrol positif, DMSO 10% sebagai kontrol negatif, dan variasi konsentrasi ekstrak daun jambu biji 10%, 20%, 30% dan 40%. Hasil penelitian menunjukkan adanya efek ekstrak daun jambu biji untuk menghambat bakteri Salmonella pullorum, dimana konsentrasi tertinggi (40%) memiliki efek yang paling baik.
PENGARUH PEMBERIAN SALEP EKSTRAK KUNYIT KUNING (Curcuma longa Linn) TERHADAP PENYEMBUHAN LUKA SAYAT PADA TIKUS PUTIH (Rattus norvegicus) Muthia Milasari; Abdul Wahid Jamaluddin; Yuko Mulyono Adikurniawan
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (297.922 KB) | DOI: 10.36387/jiis.v4i1.268

Abstract

Turmeric is one of the herbal contents substancials that believed help wound healing process. Scientifically, turmeric has been shown to have an anti-inflammatory and choleretic effect. The curcumin compound has potential effects as antimicrobial and antioxidant that can accelerate the re-epithelialization and migration of cells such as myofibroblast, fibroblasts and macrophages. Those are compounds for wound healing. The aims of this study is to know the effect of yellow tumeric extract oinment in wound healing based on the time of wound close and morphological changes are compared with the controls. This study was carried out by experimental test. The experimental animals were divided into 5 groups, each group consisted of 5 animals. Each group is treated, among others by giving 10%, 20%, and 30% yellow turmeric extract ointment (treatment groups), povidone iodine 10% ointment (positive control) and ointment base (negative control). The rats were given an incision in the back of the vertebrae with square pattern around ±2cm to fascia. Yellow turmeric extract ointment was applied to rat wounds 2 times a day and observed daily from day 1 to day 14. Data were analyzed using ANOVA (analysis of variance). The results showed a significant difference in 5 groups (P< 0.05). There were differences in the results of the study between the treatment group (10%, 20% and 30% yellow tumeric extract ointment), positive control (povidone iodine 10% ointment) and negative control group (ointment base) which showed a faster treatment group to heal wounds compared the control group. The study reveals that 10% yellow turmeric extract ointment is best in accelerating wound healing.
EFEK ADAPTOGENIK EKSTRAK ETANOL KULIT BUAH MANGGIS (Garcinia mangostana L.) PADA MENCIT (Mus musculus) MENGGUNAKAN METODE SWIMMING ENDURANCE TEST Abdul Wahid Jamaluddin; A. Magfira Satya Apada
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (152.796 KB) | DOI: 10.36387/jiis.v5i1.385

Abstract

Adaptogenic activity was related to antioxidant activity which can reduce the number of free radicals, which in turn will reduce stress and improve body balance. Mangosteen rind (Garcinia mangostana L.) with a large antioxidant content promises to be Adaptogen. This study aims to examine the Adaptogenic effects of Ethanol Extract of mangosteen peel (Garcinia Mangostana L.) Using the Swimming Endurance Test (SET) in Mice. Simplicia of Mangosteen Fruit extracted by maceration using 96% ethanol, then tested its Adaptogen activity based on swimming endurance test. The group consisted of negative control (NaCMC 1%), positive control (Vit C. 100 mg / kg BB) and 3 groups treatment of ethanol extract of mangosteen peel ranging from 100, 200 and 400 mg / kg BB where all groups were given oral 1x1 oral administration for 7 days and on the 8th day, a SET test were performed. After that, data analysis was performed statistically. The results showed that the ethanol extract of mangosteen peel had the ability to be Adaptogenic where mice swimming in all groups given mangosteen peel extract was longer than the negative group with a significant difference (p <0.05). Ethanol extract of mangosteen peel showed a strong adaptogenic antistress effect in mice based on increased swimming time ability of mice.
AKTIVITAS INFUSA DAUN JAMBU BIJI (PSIDIUM GUAJAVA L.) TERHADAP NEMATODA HAEMONCHUS SP. DARI SAPI BALI (BOS SONDAICUS) SECARA IN VITRO Nur Ilmi Rahmiati; Abdul Wahid Jamaluddin; Bone Ramadhan
Jurnal Agrisistem Vol 14 No 1 (2018): Jurnal Agrisistem
Publisher : Unit Penelitian dan Pengabdian Masyarakat Politeknik Pembangunan Pertanian Gowa

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Abstract

Haemonchus sp. merupakan cacing pada saluran pencernaan yang sering menyerang ternak seperti sapi, domba dan kambing. Cacing lambung ini sangat berbahaya karena selainmenghisap darah, daya perkembangbiakannya juga sangat tinggi. Untuk menangani masalah cacing ini umumnya digunakan obat cacing sintetik dari golongan benzimidazole, namun telah dilaporkan bahwa penggunaan antelmintik golongan ini secara tidak tepat dapat menyebabkan resistensi. Untuk menangani kasus resistensi dibutuhkan alternatif pengobatanbaru. Penelitian ini bertujuan untuk mengetahui aktivitas infusa daun jambu biji terhadap cacing Haemonchus sp. dari sapi Bali. Penelitian ini dilakukan pada bulan Juli 2017 di Laboratorium Fitokimia Fakultas Farmasi Universitas Hasanuddin dan Balai Besar Veteriner Maros dengan menggunakan sampel sebanyak 90 ekor cacing untuk tiga kali pengulangan. Sampel dibagi menjadi 6 kelompok, kelompok I yaitu kontrol negatif; kelompok II-V infusa konsentrasi 5%; 10%; 20%, dan 40%; dan kelompok VI yaitu kontrol positif berupa piperazine. Kelompok perlakuan masing-masing diuji pada cacing dengan melihat waktu kematian cacing. Hasil dari penelitian ini yaitu konsentrasi tertinggi perlakuan (40%) memiliki waktu paling cepat dalam membunuh cacing di antara konsentrasi perlakuan yang lain. Kesimpulan dari penelitian ini yaitu infusa daun jambu biji memiliki aktivitas terhadap waktu kematian cacing.
UJI PERBANDINGAN EFEKTIVITAS DAYA ANTHELMINTIK EKSTRAK DAUN SIRSAK (Annona muricata L.) Siti Maryam; Abdul Wahid Jamaluddin; Adryani Ris
Jurnal Agrisistem Vol 14 No 1 (2018): Jurnal Agrisistem
Publisher : Unit Penelitian dan Pengabdian Masyarakat Politeknik Pembangunan Pertanian Gowa

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Abstract

Daun sirsak (Annona muricata L.) mengandung tanin, saponin, alkaloid yang diketahui memiliki efek anthelmintik. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak daun sirsak terhadap mortalitas Ascaris suum dan Ascaridia galli serta mengetahui perbedaan efek pemberian ekstrak daun sirsak terhadap Ascaris suum dan Ascaridia galli. Penelitian ini bersifat ekperimental laboratorik. Subjek penelitiannya adalah cacing Ascaris suum dan Ascaridia galli yang aktif bergerak. Subjek dibagi dalam 5 kelompok, setiap kelompok terdiri dari 5 cacing. Kelompok kontrol positif menggunakan Piperazin citrate 1%, kelompok kontrol negatif menggunakan Na CMC 1% sedangkan kelompok perlakuan terdiri dari ekstrak daun sirsak (Annona muricata L.) konsentrasi 40%, 10%, dan 2,5%. Cacing direndam dalam larutan uji dan pengamatan dilakukan setiap 15 menit dan dihitung jumlah cacing yang mati. Data dianalisis dengan ANOVA dan Mann-Whitney U Test. Hasil pengamatan rarata waktu kematian Ascaris suum dan Ascaridia galli berbeda. Pada kelompok Ascaris suum rerata peringkatnya 33,72 lebih tinggi dari pada rerata Ascaridia galli, yaitu 17,28. Yang berarti waktu kematian Ascaris suum lebih lama jika dibandingkan dengan waktu kematian Ascaridia galli. Kesimpulannya adalah efektivitas daya anthelmintik ekstrak daun sirsak pada Ascaridia galli lebih cepat dibandingkan pada Ascaris suum yang disebabkan struktur lapisan Ascaris suum lebih tebal sehingga proses penyerapan ekstrak lebih lama.
Co-Authors A. Ika H.A. Imran A.B Adikurniawan, Yuko Mulyono Adriyani Ris Adryani Ris Ainun, Hasri Amir, Muhammad Nur Anak Agung Putu Joni Wahyuda Andi M. S. Apada Andi Magfira Satya Apada Andi Muhammad Taufan Apada, Andi Magfira Satya Aprilia, Eka Arifah, Sitti Ayu Lestari Azzahrah, Nur Faatimah Baso Yusuf Bone Ramadhan Carisma Sumule Ciputra, Lyvia Angeline Dwi Kesuma Sari Febyana, Andi Fedri Rell Handayani, Nur Atikah Hastang, Hastang Hikmah, Hikma Hosea, Cindy Trie Permatasari Ikliptikawati, Dini Kurnia Imran A.B, A. Ika H.A. Jamilah, Ainun Kadek Evi D.P. Dewi Lucia Musimin Lucia Muslimin M. Natsir Djide Magfira Satya Apada Mapparenta, Bulan Allu Mappiara, Muhammad Afiq S. Minarfa, Tiara S Muhammad Alamsyah Muhammad F. Mursalim Muhammad Fadhil Shalih Muhammad Fadhlullah Mursalim Muhammad Fadhlullah Mursalim Muhammad Fadhlullah Mursalim Muhammad Muflih Nur Muhammad Natsir Djide Mursalim, Muhammad Fadhlullah Musdalifah Musdalifah Muthia Milasari Nahariah Nahariah, Nahariah Nikita Tenritojang Mustafa Nur Ilmi Rahmiati Nur Sriani Rezki Nurmauliah Syaharuddin Nurul Fajriani M Purba, Fika Yuliza Rasdiyanah Rasdyanah Rasdyanah Rian Hari Suharto Ris, Adryani Risyani, Risna Rizal, Yuki Nurindar RR. Ella Evrita Hestiandari Sarah, Ruhil Aziz Siti Maryam Sitti Arifah Suharto, Rian Hari Suryadi Pappa Suryadi Pappa Syahbar, Lutfiah Kurnia Wa Ode Santa Monica waode santa monica WAODE SANTA MONICA Yuko Mulyono Adikurniawan Zainal Abidin Kholilullah Zainal Abidin Kholilullah Zulfikri Mustakdir