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Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya
Published by Universitas Muhammadiyah Surabaya
ISSN : 25412272     EISSN : 25489526     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Arjuna Subject : -
Articles 301 Documents
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Positive Effect of Konjac Glucomannan on Lowering Blood Pressure in Hypertensive Wistar Rats Putra, Bryan Anggara; Mashudi, Sugeng; Sari, Alfia Pradita; Afriani, Fany Risma; Aziz, Yaya Sulthon; Sansuwito, Tukimin bin
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 02 (2024): Qanun Medika Vol 08 No 02 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i02.21297

Abstract

Hypertension is a non-communicable disease that is currently a top priority for global health. Commonly offered anti-hypertensive pharmacological therapies such as ACE-inhibitors are known to have side effects in long-term use, unlike herbal glucomannan, which has been used as a treatment for patients with type 2 diabetes. The purpose of this study was to see what effect applying glucomannan supplements for 6 hours had on blood pressure parameters obtained from the wistar rat subjects who had hypertension. Twenty five male Wistar rats with normal systolic blood pressure (sBP) ± 110 mmHg were involved in the study; they received a 10% high salt diet for 14 days. They were divided into 4 groups: the positive control group G1 received captopril at 25 mg/kg of body weight and the treatment groups G2  50 mg KGM. Blood pressure measurement using sphygmonanometers with diastolic blood pressure (dBP) is the exclusion criterion of the study. Data analysis is done with a paired sample t-test. Blood pressure in each group decreased after 6 hours of intervention, but the most significant results were obtained in the G5 group that received glucomannan 100 mg/kg bb. In conclusion, Glucomannan can lower blood pressure; this potential is the same as that of red ginger, which modulates the production of angiotensin-corventing enzymes.
Anxiety Level of Pregnant Women at Siti Khodijah Muhammadiyah Sepanjang Hospital During COVID-19 Pandemic Dwi Ariningtyas, Ninuk; Islamy, Aulia Nuril; Subagyo, Roni; Anas, Muhammad
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 02 (2024): Qanun Medika Vol 08 No 02 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i02.21374

Abstract

Pregnant women are one of the vulnerable groups who have to face the unpleasant effects of the COVID-19 pandemic. One of the effects is the psychological impact that is bad for both the mother and the fetus. This study aims to describe the level of anxiety experienced by pregnant women during the COVID-19 pandemic at Siti Khodijah Muhammadiyah Sepanjang Hospital. The results of this study are expected to be used as information to help overcome more serious mental health problems. This research uses using quantitative descriptive design with a cross-sectional approach. The sample of this study was 112 pregnant women who met the research criteria. This research was conducted by giving them questionnaires consisting of their age, job, parity, gestational age, history of COVID-19 illness, history of mental problems, knowledge about COVID-19, and level of anxiety. Statistical analysis showed 84.8%, 8.9% and 6.3% of pregnant women experience low, moderate, and concerning levels of anxiety, respectively. The majority of pregnant women are primigravida, aged 20-35 years, with a gestational age of 28-41 weeks, housewives, and the level of knowledge about COVID-19 is very good. Correlation analysis using Kendall's tau-b showed a significance value of 0.038 (<0.05), which means a relationship exists between the level of knowledge about COVID-19 and the level of anxiety of pregnant women. In conclusion, the level of anxiety of pregnant women the most is low anxiety, followed by moderate and concerning levels of anxiety.
Karakteristik Pasien Tuberkulosis Paru Dengan HIV di Rumah Sakit Umum Daerah Dr Harjono Ponorogo Periode Januari 2018 - Desember 2022 Kusuma Dewi, Anindya Zalfaa; Pratama A., Ronald; Taruna, Dody; M. Dikman, Irmawati; Soedarsono, Soedarsono; Levani, Yelvi
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 02 (2024): Qanun Medika Vol 08 No 02 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i02.21666

Abstract

Tuberculosis (TB) is the most common opportunistic infection in people living with HIV/AIDS in Indonesia, and HIV infection promotes Mycobacterium tuberculosis infection. In ODHIV, the probability of contracting TB is 10% per year. According to the Indonesian Ministry of Health, East Java is in second place with 71,909 cases and has the second highest number of AIDS patients and 824,000 TB cases in Indonesia. This study aims to determine the characteristics of pulmonary tuberculosis patients with HIV at DR Harjono Ponorogo Hospital for the period January 2018 - December 2022. This study applied descriptive research methodology with quantitative techniques with secondary data from medical records of pulmonary TB patients with HIV at Dr. Harjono Ponorogo Hospital for the period January 2018 - December 2022.  The results showed a total sample of 130 medical records, there were several characteristics of TB patients with HIV, namely the highest age group of 30-39 years by 29.2%, more in male gender 73%. More patients had last high school education 38.5%, more treatment duration in patients who did for 9 months 61.5% and the results showed more patients with poor prognosis 56%. In conclusion, the characteristics of TB patients with HIV with the highest group at the age of 3-39 years, having male gender, more high school education, with more treatment duration of 9 months, and the results showed a poor prognosis.
The relationship of body mass index, mid-upper arm circumference, and waist circumference with the blood pressure in elderly indriyani, indriyani; Tiara, Rury; Noviyanti, Noviyanti; Aprilia, Cintiya
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 01 (2025): Qanun Medika Vol 09 No 01 January 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i01.21888

Abstract

Life expectancy is one of the most popular summary measures for a population's general health. Growing Life Expectancy predicts a rise in senior citizens in the coming years. An increase in health issues among the elderly may result from an aging population. Anthropometric measures of nutritional status can reveal nutritional status, which may contribute to the development of cardiovascular risk; however, research on this topic in the elderly is still lacking. This study uses a cross-sectional design and a sample size of 60 elderly people who live in Muhammadiyah University Palembang's development village. Blood pressure and anthropometric measures were taken by researchers. Throughout the course of five minutes, three separate readings of the blood pressure, waist circumference, mid-upper arm circumference, and body mass index (BMI) were obtained. The means of these measurements were then analyzed. Diastole Blood Pressure/DBP was substantially correlated with BMI, WC, and MUAC (P = 0.001; r = 0.407; P = 0.003; r = 0.381 & P = 0.017; r = 0.307, respectively). In conclusion, systolic and diastolic blood pressure in the elderly are positively associated with anthropometric measures of body fatness, particularly BMI.
Evaluating the effectiveness of Thiel embalming solution for preserving cadavers in anatomy and surgical education Indrawan, I Made Rayo Putra; Margiana, Ria
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 01 (2025): Qanun Medika Vol 09 No 01 January 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i01.21946

Abstract

Cadavers have played a crucial role in anatomy teaching, owing to their resemblance to the anatomical structures found in living individuals. To optimize the utilization of cadavers, embalming procedures that involve the application of chemical fixative agents are needed. The "soft embalming" approach, which involves various salts as fixating agents, was first developed by Walter Thiel. Although the Thiel solution has demonstrated efficacy in enhancing tissue elasticity, consistency, and color, a study is needed to find the most suitable for embalming with this solution to maximize its utility in the context of anatomy and surgical education. The study results show that the Thiel solution produces the best outcomes for its flexibility, uniformity, and color, which is optimal for anatomical and surgical teaching. The efficacy of Thiel's solution for preserving cadavers for educational intentions is noteworthy for the study of anatomy and surgical procedures. The advantageous characteristics of Thiel embalming include flexibility, consistency, and natural coloring. Nevertheless, it is crucial to consider the restrictions associated with preserving the brain, spinal cord, eye, and musculoskeletal tissues. In conclusion, the utilization of Thiel solution has proven to be an efficient embalming agent for preserving cadavers in the fields of anatomy and surgery education, besides brain, spinal cord, eye, and musculoskeletal systems, should be reconsidered.
Hubungan Kecanduan Gawai dengan Kejadian Insomnia pada Mahasiswa Fakultas Kedokteran Universitas Muhammadiyah Surabaya Djalilah, Gina Noor; Oktaviyanti, Lucky Dyah; Prasetya, Era Catur; Indrawati, Nina Devi; Nugraha, Adi Satria
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 02 (2024): Qanun Medika Vol 08 No 02 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i02.22069

Abstract

Insomnia is a condition characterized by difficulty falling asleep, staying asleep, or waking up early despite having the opportunity to sleep. Insomnia can reduce the quality and quantity of sleep, leading to various negative effects on an individual's health and well-being. One of the potential causes of insomnia is excessive smartphone use, which can lead to addiction. Smartphone addiction can affect people of all ages, from children to adults. It has been associated with several adverse effects, including insomnia, recurrent and prolonged headaches, and fatigue. This study aimed to investigate the relationship between smartphone addiction and insomnia among medical students at the University of Muhammadiyah Surabaya. This cross-sectional observational study involved 87 medical students from the 2019, 2020, 2021, and 2022 cohorts. The sample was selected using a proportionate stratified random sampling technique. Data were collected using the Smartphone Addiction Scale (SAS) and the Insomnia Rating Scale (KSPBJ-IRS) through a Google form. The data were analyzed statistically using the Chi-square test in SPSS version 25. The Chi-square test showed a p-value of 0.005 (<0.05), indicating a statistically significant relationship between smartphone addiction and insomnia among medical students at Muhammadiyah University of Surabaya. In conclusion, the study found a significant relationship between smartphone addiction and insomnia among medical students at Muhammadiyah University of Surabaya. This suggests that excessive smartphone use may contribute to sleep disturbances in this population.
Larvicide activity of ethanol extracts from Zodia (Evodia suaveolens S.) leaves and Cananga (Cananga odorata) flowers on Aedes aegypti larvae Dewi, Purista Tiara; Dewi, Listiana Masyita
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 01 (2025): Qanun Medika Vol 09 No 01 January 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i01.22132

Abstract

Controlling Aedes aegypti population in Dengue management programs is often carried out using high doses of synthetic insecticides, such as temephos, that may lead to resistances. An alternative of natural ingredient such as Zodia (Evodia suaveolens S.) leaves, that containing evodiamine and Cananga (Cananga odorata) flower that containing linalool, appears to be a promising larvicide. This study aims to determine the effectivity of ethanol extracts from Zodia leaves and Cananga flowers on the mortality of Aedes aegypti larvae. This experimental study using Aedes aegypti larvae at stage of III-IV. Each ingredient was extracted by the maceration method and then prepared at concentration of 2.5% and 5%. PEG 400 was also added as a diluent. Observations performed every 6 hours, for 24 hours. Data analysis using Kruskal Wallis test and Dunn's test. Within 24 hours, in each of study group, there was 100% larval mortality. The Kruskal Wallis test resulting p-value of <0.05. From Dunn’s test, comparisons between each study group and the negative and positive control groups yielded p-values <0.05 and 1.000, respectively. Thus, it can be said that ethanol extracts from Zodia leaves and Cananga flowers are as effective as temephos as larvicide on Aedes aegypti larvae
Prevalence And Pattern Sensitivity Multidrug Antibiotics Resistant Pseudomonas aeruginosa in the High Care Unit at Dr. Soetomo General Academic Hospital Period 2022-2023 Kusumawati, Ratna; Koendhori, Eko Budi; Mertaniasih, Ni Made; Ikhwani, Irfan Arif; Hidayat, Dimas Firman; Levani, Yelvi; Paramitha, Ayu Lidya
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 02 (2024): Qanun Medika Vol 08 No 02 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i02.22152

Abstract

The prevalence of Multidrug antibiotic-resistant Pseudomonas aeruginosa (MDRPA) has been increasing during the decade And has become attention in hospital patients. This retrospective descriptive descriptive aimed to determine the prevalence of MDRPA and its sensitivity patterns. Data were taken from results of bacterial culture and antibiotic resistance tests from various clinical specimens from patients at Dr. Soetomo General Academic Hospital throughout 2022-2023. The resistance test was carried out using a Vitek 2 compact instrument. MDRPA is defined as Pseudomonas aeruginosa that is not sensitive to three or more of the following classes of antibiotics: meropenem or imipenem, ciprofloxacin, gentamicin or amikacin, ceftazidime or cefepime, and piperacillin/ tazobactam. The prevalence of MDRPA was 57.0%. MDRPA isolates were also the most common origin from the burn unit and HCU A (high care unit A), mostly from pus specimens and sputum. Pseudomonas aeruginosa sensitivity was best with piperacillin/tazobactam (55.5%), meropenem (54.8%), amikacin (47.5%), gentamicin (46.5%), cefepime (46.3%), ceftazidime (45.0%), ciprofloxacin (44.7%) and aztreonam (43.2%). The sensitivity of MDRPA to antibiotics is much lower than that of Pseudomonas aeruginosa. This study showed high number of MDRPA specifically in Surabaya and the pattern sensitivity of Pseudomonas aeruginosa can become guidelines in choosing antibiotics treatment for patients.
Mesial Temporal Lobe Epilepsy as a Common but Elusive Case: A Case Report Junior, Darren; Wulandari, Putu Kintan; Harkitasari, Saktivi; Sumardika, I Wayan; Sumadewi, Komang Trisna
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 01 (2025): Qanun Medika Vol 09 No 01 January 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i01.22259

Abstract

Epilepsy is a common neuronal disorder that could include partial or generalized seizures due to abnormal brain electrical activity. A 32-year-old female patient was presented to the emergency room with a chief complaint of seizure. The seizure semiology started with epigastric pain, which then progressed into sudden speech arrest. Afterward, the patient experienced left-sided head movement followed by jerkings on the left hand. The patient then became unconscious and experienced full body rigidity. Physical examinations, vital signs, and laboratory results showed no abnormalities. Diagnostic assessments only showed unspecific signs of diffuse cerebral edema through a CT Scan and an atrophy of the right hippocampus with a slight increase in FLAIR signal intensity and dilatation of the right lateral ventricle pericornu through MRI. The patient was given phenytoin and folic acid twice daily. The presence of right mesial temporal sclerosis served as a possible cause of epilepsy in this patient despite having several obscurities. The patient showed atypical signs of generalized tonic seizure progression, adult-onset seizures, and increased MRI FLAIR signal intensity. More detailed examinations and constant reports of epilepsy cases are highly needed among physicians to provide more specific methods and tools to diagnose, classify, and treat epilepsy in the future.
Emergency Pregnancy with Severe Preeclampsia and Total Atrioventricular Block In A 28-Year-Old Woman Cholili, Muhamad Nofa; Irwanto, Yahya
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 01 (2025): Qanun Medika Vol 09 No 01 January 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i01.22296

Abstract

The co-occurrence of preeclampsia with bradycardia due to total atrioventricular block (TAVB) during pregnancy is a rare yet severe phenomenon. There is limited literature available on this specific combination. This case report aims to contribute valuable insights by documenting the clinical presentation and management of a 28-year-old woman who is diagnosed with severe preeclampsia and total atrioventricular block during pregnancy.   A 28-year-old pregnant woman was referred to the emergency room with dyspnea and vaginal discharge. She had a history of cardiac issues, including atrial septal defect and total atrioventricular block. Her blood pressure was 206/129 mmHg, and a pulse rate of 67 beats per minute. Then, she was diagnosed with severe preeclampsia, hypertensive emergency, and impending eclampsia with a suspect congenital disease contributing to her atrioventricular block. The patient underwent urgent cesarean section intrauterine stabilization and received postoperative care. Postoperatively, the patient reported no further dyspnea or bradycardia. The history of salbutamol usage and the activation of plasminogen activator inhibitor-1 (PAI-1) in patients with atrial septal defects (ASD) is suspected as a potential etiological factor in the pathophysiology of preeclampsia during pregnancy. TAVB can be induced by congenital ASD. In conclusion, the use of salbutamol and activation of PAI-1 in patients with TAVB induced by ASD are suspected as potential causes of preeclampsia during pregnancy.

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