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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Published by Perkumpulan Obstetri dan Ginekologi Indonesia
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 1,731 Documents
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A Case Series on Pregnant Patients with Ovarian Cysts and Management of Potential Complications Hermawan, Gezta Nasafir; Laihad, Bismarck Joel
Indonesian Journal of Obstetrics and Gynecology Volume 13. No. 3 July 2025
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v13i3.2004

Abstract

Abstract (English) Objective: To report a series of ovarian cyst cases in pregnancy that we diagnosed in our obstetrics and gynecology department; and to provide literary perspective in management of potential complications. Methods: A case series Case: We present three cases of pregnant patients with ovarian cysts diagnosed at different trimesters of gestational age. Patients included in this case series were shown to have cysts at the time of sonographic examination. Each patient displayed different complications and underwent specific management for each complication which includes laparotomy and emergency cesarean section. All patients were discharged in clinically stable conditions and the mass was evaluated for further histopathologic examination. This case series will also discuss possible complications of pregnancy with ovarian cysts, and the prevalence of each complication based on the gestational age. Due to its potential complications, ovarian cysts in pregnancy must be accurately evaluated and given appropriate management. Conclusion: Ovarian cysts in pregnancy must be evaluated accurately so that appropriate management is carried out. Clinicians should be aware of cyst complications during pregnancy. Keywords: Ovarian Cysts, Pregnancy, Potential Complications
Relationship of History of Hypertension with Severity and Onset of Preeclampsia: A Cross-Sectional Study Adnan, Muhammad Luthfi; Weningtyas, Vyanda Sri; Pramaningtyas, Miranti Dewi; Wahyana, Eka Budi
Indonesian Journal of Obstetrics and Gynecology Volume 13. No. 3 July 2025
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v13i3.2168

Abstract

Objective: This study aimed to find correlation between a history of hypertension with severity and onset of preeclampsia.Methods: A retrospective cohort study with retrospective analysis of medical record data in patients with preeclampsia and severe preeclampsia from November 2021 – February 2022 was conducted at dr. Soediran Mangun Sumarso Regional General Public Hospital, Wonogiri, Central Java. Analysis was performed between the history of hypertension with severity and onset (<34 weeks and age ? 34 weeks gestational age). Data analysis was performed using SPSS software with univariate Chi-Square analysis.Results: A total of 44 medical record data were obtained in this study. A total of 20 patients (45.5%) had a history of hypertension and 24 (55.5%) patients had no history of hypertension. A total of 23 patients (52.3%) were diagnosed with severe preeclampsia and 21 patients (47.7%) were diagnosed with preeclampsia. Based on statistical analysis, it was found that there was no significant correlation between the history of hypertension and the severity of preeclampsia (p=0.741; OR (CI 95%): 0,818 (0,249 – 2,690)) and onset (p=0.88; OR (CI 95%): 1,133 (0,222 – 5,788)).Conclusion: There is no relationship between history of hypertension with the severity and onset of preeclampsia. Further studies with larger populations are needed to analyze the relationship between history of hypertension and preeclampsia.Keywords: blood pressure, cardiovascular disease, hypertension, onset, preeclampsia.
Effect of Bengkoang (Pachyrhizus erosus) Extract on Estrogen Receptor-?, Progesterone Receptor Expression, and Follicle-Stimulating Hormone Levels Suryanti; Putri Ardela, Mayasari; Frenty Hadiningsih, Eka; Winarsih, Sri; Noorhamdani; Nurseta, Tatit; Norahmawati, Eviana
Indonesian Journal of Obstetrics and Gynecology Volume 13. No. 3 July 2025
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v13i3.2180

Abstract

Abstract Objective: Progesterone functions by inhibiting the release of Gonadotropin-Releasing Hormone (GnRH), which decreases Follicle-Stimulating Hormone (FSH) levels and converts them into hypoestrogens. This condition affects the expression of steroid, estrogen, and progesterone receptors, contributing to endometrial proliferation and secretion during the menstrual cycle. Methods: This study aims to demonstrate that Bengkoang extract administration increases the expression of Estrogen Receptor (ER), Progesterone Receptor (PR), and Follicle-Stimulating Hormone (FSH) in Wistar model rats. This study divided 25 female Wistar rats into five groups: one control group without progesterone and Bengkoang extract and four treatment groups injected with progesterone. After exposure, Bengkoang extract was administered to three treatment groups at doses of 70 mg/200 g BW/day (treatment 1), 140 mg/200 g BW/day (treatment 2), and 280 mg/200 g BW/day (treatment 3). Results: The results showed an increase in the expression of Estrogen Receptor- ? (Er?), Progesterone Receptor (PR), and Follicle-Stimulating Hormone (FSH) levels in treatment 1, treatment 2, and treatment 3 groups compared to the KP with p <0.05 Conclusion: The study investigating the effect of Bengkoang (Pachyrhizus erosus) extract on estrogen receptor-? (ER?), progesterone receptor (PR) expression, and follicle-stimulating hormone (FSH) levels has demonstrated significant findings. Keywords: Estrogen, Estrogen receptor-?, Follicle-stimulating hormone, Pachyrhizus erosus, Progesterone, Progesterone receptor
Characteristics and treatment in patient with Vaginismus in East Java Indonesia Kurniawati, Eighty Mardiyan; Hardianto, Gatut; Paraton, Hari; Setyo Hadi, Tri Hastono; Widyasari, Anis; Rahmawati, Nur Anisah
Indonesian Journal of Obstetrics and Gynecology Volume 13. No. 3 July 2025
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v13i3.2231

Abstract

Background - Vaginismus is still an under-researched case of women's health despite its universal prevalence. Aim -This study aims to explore the characteristics of vaginismus in East Java Indonesia. Methods- The subjects in this study were all new female patients with Vaginismus was found in a single hospital - East Java Indonesia in 2022. The data used in this study are secondary data obtained from the medical records. Descriptive data are presented as numbers and percentages for categorical data. Results – Vaginismus was found in a single hospital - East Java Indonesia. Based on medical record data, throughout 2022 there will be 60 patients with a diagnosis of Genito Pelvic Pain Penetration Disorder (GPPPD). The results of the assessment of patient characteristics showed that almost all patients were of reproductive age. Most of the respondents have been married for more than 1 year. Management is carried out independently and collaboratively. A total of 60 patients underwent anamnesis and physical examination. Complaints experienced by patients are failure to penetrate. Treatment was done using Botox injections, dilatation, hymenectomy, and consultation to psychiatrist and andrologist. Conclusion - Management in cases of Vaginismus requires cross-professional collaboration such as psychiatrists and andrology. The treatment given also tends to be complex.
Management of Severe Preeclampsia with Anemia in Pregnant Women with Covid-19 Infection : A Multidisciplinary Approach Handayani, Ririn; Anggraeni, Ernawati; Sari, Melati Puspita; Handayani, Yuni; Cahyono, Hendra Dwi
Indonesian Journal of Obstetrics and Gynecology Volume 13. No. 3 July 2025
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v13i3.2329

Abstract

Coronavirus disease 2019 (COVID-19) is a disease that is currently pandemic almost worldwide, with the first case in Indonesia on March 2, 2020, spreading rapidly across the entire country. Pregnant women are a vulnerable group to experience health disorders, especially infectious diseases, due to changes in physiological body and immune response mechanisms within their bodies. In this study, we report a case of COVID-19 in a 31-year-old pregnant woman at 30-31 weeks of gestation, who is pregnant with her second child and complained of leaking amniotic fluid and shortness of breath. Physical examination results showed: positive SARS-CoV-2 antigen swab test, BP 156/112 mmHg, T (36.0°C), heart rate 107 beats per minute, respiratory rate 30 breaths per minute, fetal heart rate 144 beats per minute, SpO2 97%, urine protein +4, Hb 4.4 g%. Vaginal toucher examination revealed cervical dilation of 1 cm, negative for amniotic fluid leakage, and cephalic presentation. Spontaneous delivery process. The baby was born normally, female, APGAR score 1-2, weight 900 grams, length 27 cm, positive anus. Complications accompanying pneumonia, metabolic acidosis, anemia, melena, coagulopathy. This case report contains clinical descriptions, diagnosis, and management of care for pregnant women with Covid-19.
Multiple Congenital Anomalies with Breech Presentation: Dilemma in Diagnostic Procedures, Delivery Management, and Counseling in Developing Country Gusasih, Bahar Sangkur; Pramatirta, Akhmad Yogi; Aziz, Muhammad Alamsyah; Kurniadi, Andi
Indonesian Journal of Obstetrics and Gynecology Volume 13. No. 3 July 2025
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v13i3.2380

Abstract

Objective: Multiple congenital anomalies present significant diagnostic and management dilemmas, particularly in resource-limited settings. Globally, these conditions affect approximately 1 in 33 infants and are a major contributor to perinatal mortality. We report a rare case of a term pregnancy with severe, undiagnosed multiple congenital anomalies, highlighting the challenges in diagnosis, delivery management, and counseling in a developing country.Case Illustration: A 22-year-old primigravida presented at 35-36 weeks of gestation in active labor with a fetus in breech presentation. Antenatal ultrasonography at 27 weeks had revealed a single live fetus with severe fetal growth restriction, polyhydramnios, and multiple structural anomalies suspicious for an underlying trisomy. Amniocentesis was offered for a definitive diagnosis but was declined by the family. A female neonate was delivered via spontaneous vaginal breech delivery, with low APGAR scores. The infant was admitted to the High Care Unit for respiratory support but passed away the following day due to respiratory failure. The family had opted for a Do Not Resuscitate (DNR) status.Conclusions: In cases of severe fetal anomalies detected by ultrasound, advanced genetic testing like NIPT followed by diagnostic testing should be offered to facilitate definitive diagnosis and counseling. Delivery decisions in such cases should be individualized, prioritizing maternal safety while considering the fetal prognosis. This case underscores the urgent need for improved access to and awareness of genetic counseling and diagnostic services in developing countries to optimize perinatal outcomes.Keywords: breech presentatoin, developing countries, genetic counceling, multiple congenital anomalies, prenatal diagnosis.
Emotional Impact of In Vitro Fertilization (IVF): Anxiety, Depression, and Their Relationship with Pregnancy Outcomes Agiananda, Feranindhya; Natadisastra, Raden Muharram; Amir, Nurmiati; Irwanto; Aninditha, Tiara; Wibisono, Sasanto; Wahmurti, Tuti; Kekalih, Aria; Karnasih, Artasya; Samjunanto, Achmad; Puspaseruni, Putri Air; Velyani, Dyani Pitra; Prayangga, Regina
Indonesian Journal of Obstetrics and Gynecology Volume 13. No. 3 July 2025
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v13i3.2626

Abstract

Objectives: Infertility can significantly impact women's physical and psychological health. Numerous treatment options are commonly pursued, with IVF often considered the last resort for infertile couples. However, IVF is associated with increased stress at every stage, potentially influencing women's perceptions and experiences throughout the procedure. This research examines anxiety and depression faced by women at different stages of IVF and analyzes their association with pregnancy outcomes. Methods: This cohort study was conducted at Dr. Cipto Mangunkusumo General Hospital and Dr. Sander B. Daya Medika Clinic from May 2018 to March 2023. Data were collected using questionnaires and assessments during IVF, focusing on the evaluation of anxiety, depression, and pregnancy outcomes. Chi-square and Fisher’s exact test was used to assess associations between variables, while Friedman ANOVA was used for longitudinal analysis of anxiety and depression scores during IVF. Results: The final analysis comprised 61 participants. The study revealed significant changes in anxiety and depression throughout IVF. Both anxiety (p < 0.001, Kendall’s w = 0.19) and depression levels (p = 0.001, Kendall’s w = 0.121) showed a significant rise across the IVF timeline. There is no statistically significant association between anxiety and depression scores and pregnancy outcomes across three measurement points during IVF (p > 0.05). Conclusion: Anxiety and depression significantly increase during IVF but do not affect clinical pregnancy rates. These findings highlight the importance of mental health screening and psychiatric support during IVF to ensure women’s comfort and enable them to navigate IVF more effectively. Keywords: Anxiety, Depression, Pregnancy Outcomes, Women, In Vitro Fertilization (IVF)
Vaginal Microbial Patterns and Matrix Metalloproteinase-9 Levels in relation to Premature Rupture of Membranes Muliati, Tuty; Chalid, Maisuri Tadjuddin; Leonardy, Rudy Butje; Hamid, Firdaus; Wewengkang, Ellen; Asni, Sitti Nur
Indonesian Journal of Obstetrics and Gynecology Volume 13. No. 3 July 2025
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v13i3.2741

Abstract

Introduction: The premature rupture of membranes (PROM) before the onset of labor, characterized by the painless leakage of fluid from the vagina, can lead to fetal distress and increase the risk of cesarean section. This study analyzed the microbial patterns and matrix metalloproteinase 9 (MMP-9) levels in cases of PROM. Methods: This was an observational study with cross-sectional design. Samples were collected from 60 pregnant women diagnosed with PROM who underwent examination and treatment at St. Khadijah I Hospital in Makassar in November 2023. Statistical analysis was performed using the Independent Samples T-Test for microbial patterns and MMP-9 levels. Results: The MMP-9 level in PROM group was significantly higher (1706,78 ± 386,36) compared to non-PROM group (1328,20 ± 1556,22) with p = 0.006. For microbial pattern, E. coli was the predominant bacteria in PROM group (72,0%) compared to non-PROM group (28,0%) with p = 0.004. Conclusion: The results of this study indicate that high MMP-9 level and predominant E. coli presence in the vaginal swab may increase the risk of PROM.
Feasibility Study For Birth Defect’s and Congenital Abnormalities’s Integrated Service In A Low-Middle Income Country Saroyo, Yudianto Budi; Firmansha Dilmy, Mohammad Adya; Salsabila Putri, Cut Tisya; Islamah, Rachelya Nurfirdausi; Budiman, Jenica Xaviera; Rumondang, Amanda; Purwosunu, Yuditiya; Irwinda, Rima; Rohsiswatmo, Rinawati
Indonesian Journal of Obstetrics and Gynecology Volume 13. No. 3 July 2025
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v13i3.2783

Abstract

Background: Congenital abnormalities are anatomical and physiological abnormalities that are present in babies from birth. One of the main causes of high infant mortality and neonatal mortality in Indonesia is congenital abnormalities in babies. This study describes the prevalence of congenital abnormalities in Dr. Cipto Mangunkusumo Hospital, as a tertiary referral hospital in Indonesia, which requires integrated healthcare service to be treated well. Methods: Data obtained from 323 patients at Dr. Cipto Mangunkusumo General Hospital are collected in a year, to be further analyzed in retrospective cohort study. Collected data includes the patients’ age, birth date, reproductive history, gestational age, and congenital abnormalities of the baby. Results: The data shows that patients with the age group of 30-39 years old dominated the cases of pregnancy with congenital abnormalities. Cases are also more dominant in the gestational age of 13 – 28 weeks (second-trimester). Most cases of abnormalities are from the central nervous system with 159 cases and followed by cardiovascular system with 130 cases. Overall prevalence of congenital abnormalities are detected within patients during prenatal screening in Dr. Cipto Mangunkusumo General Hospital. Conclusion: This study highlights the importance in managing congenital abnormalities and birth defects by developing an integrated service in the healthcare system to lower infant and neonatal mortality. Keywords: birth defect, congenital abnormalities, prenatal screening
A Mixed-Methods Evaluation of an Iron Supplementation Program for Adolescent Girls in Magelang City Ganap, Eugenius Phyowai; Rahmalina, Rahmalina; Dwi Cahyanti, Ratnasari; Hari Respati, Supriyadi
Indonesian Journal of Obstetrics and Gynecology Volume 13. No. 3 July 2025
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v13i3.2865

Abstract

AbstractObjective: To evaluate the implementation of the iron supplementation program for adolescent girls in Magelang City andidentify supporting and inhibiting factors.Methods: This study used a mixed-methods triangulation design with purposive sampling. Quantitative data from the MagelangCity Health Office were analyzed descriptively, while qualitative data from interviews and FGDs explored implementationbarriers.Results: The program achieved 72.2% coverage, meeting the national target. Supporting factors included regulatory planning,digital reporting via e-PPGBM, cross-sectoral collaboration, and the Aksi Bergizi initiative. However, barriers such as lack ofbudget, SOPs, human resources, and low adherence were identified.Discussion: Quantitative findings provided an overview of program success, while qualitative insights revealed operationalchallenges. Low adherence was influenced by limited awareness, unclear benefits, and perceived barriers like nausea and lackof parental support. Reporting delays and system closures also hindered performance.Conclusion: Despite meeting coverage targets, the program faces significant implementation challenges. Strengtheningbudgeting, SOPs, and human resources, along with improving adolescent awareness, is essential for future success.Keywords: Adolescent girls, iron supplementation, mixed-methods study, program evaluation.

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