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Adhar Arifuddin
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Healthy Tadulako Journal (Jurnal Kesehatan Tadulako)
Published by Universitas Tadulako
ISSN : 24078441     EISSN : 25020749     DOI : https://doi.org/10.22487
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) merupakan media komunikasi dan publikasi ilmiah di bidang ilmu kesehatan yang diterbitkan oleh Unit Penjaminan Mutu Fakultas Kedokteran Universitas Tadulako yang. Jurnal ini terbit secara berkala 4 kali dalam setahun (Januari, April, Juli dan Oktober). Jurnal Tadulako Sehat diterbitkan pertama kali pada tahun 2015. Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) menerima dan menerbitkan artikel penelitian, tinjauan pustaka dan laporan kasus di bidang kedokteran dan kesehatan.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 393 Documents
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Analysis of the Determinants Influencing Treatment Adherence Among Hypertension Patients in South Sorong Regency Salkamal, Salkamal; Adam, Arlin; Iskandar, Muhammad Ishaq; ledia, Ida; Zamli, Zamli
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 1 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i1.1555

Abstract

Background: Hypertension is a major risk factor for cardiovascular diseases, driven by lifestyle modernization and its high prevalence. Addressing treatment adherence is crucial for effective management. Objective: This study aimed to analyze the determinants influencing treatment adherence among hypertension patients in South Sorong Regency, with a specific focus on family support. Methods: A quantitative research approach was conducted in South Sorong Regency from May to June 2024. Data were collected through structured questionnaires and analyzed to assess the influence of various factors on treatment adherence. Results: The findings revealed that family support significantly influenced treatment adherence in hypertension patients. In contrast, knowledge, perception, service delivery quality, and patient satisfaction did not show a significant effect on adherence. Conclusion: Family support plays a critical role in enhancing treatment adherence among hypertension patients in South Sorong Regency. To improve adherence, it is recommended to implement family education through counseling at community health centers (puskesmas) and social media, conduct behavior change campaigns, provide family counseling, train health workers to improve service delivery, and strengthen monitoring and evaluation mechanisms for treatment adherence.
Knowledge of HIV/AIDS Among Adolescents in Indonesia: A Systematic Review Alwi, M Akbar; Hamzah, Hadzmawaty; Syarifuddin, Surya; Karlina, Lilis
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 1 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i1.1556

Abstract

Background: HIV/AIDS remains a significant public health issue globally, with adolescents being one of the most at-risk groups due to various risky behaviors. Limited access to comprehensive information contributes to the continued transmission of HIV within this age group. Objectives: This study aims to describe the level of knowledge about HIV/AIDS among adolescents in Indonesia. Methods: A systematic review was conducted by examining articles published between 2010 and 2024 that align with the study objectives. Ten relevant studies were identified and analyzed. Results: Among the studies reviewed, four reported that adolescent knowledge of HIV/AIDS was categorized as "good." Three studies indicated a "moderate" level of knowledge, and another three revealed a "poor" level. Conclusions: These findings highlight the ongoing need to enhance comprehensive HIV/AIDS education among Indonesian adolescents. Strategies should include school-based education programs, community outreach utilizing various accessible media, and integration of reproductive health education into the school curriculum.
A Retrospective Comparative Study of Clinicopathological Features in High-Grade and Low-Grade Serous Ovarian Carcinoma Ham, Jonathan; Nasser, Andi S.H.D.; Masadah, Rina; Rauf, Syahrul; Nelwan, Berti J.; Miskad, Upik A; Cangara, Muhammad H; Tawali, Suryani
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 1 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i1.1558

Abstract

Backgroud: Ovarian carcinoma is the third most common malignancy in Indonesian women after breast and cervical cancer. Serous ovarian carcinoma is the most frequent subtype, divided into low-grade and high-grade types, each with distinct genetic and biological characteristics. Objective:This study aims to compare the clinicopathological features of high-grade and low-grade serous ovarian carcinoma. Methods: A retrospective cross-sectional study was conducted using 77 paraffin-embedded samples of serous ovarian carcinoma. Clinical and pathological data including age, body mass index (BMI), age at menarche, and parity were collected and analyzed using the chi-square test. Results: Patients aged >50 years accounted for most cases, with 64.3% presenting high-grade serous carcinoma (HGSC). Overweight/obesity was observed in 40.3% of cases. Early menarche (<13 years) was reported in 78%, and 42.7% were multiparous. No significant differences were found in clinical variables between HGSC and low-grade serous carcinoma (LGSC). Histopathologically, HGSC showed more pronounced cytologic atypia, necrosis, and metastasis. Conclusion: High-grade serous carcinoma demonstrates greater aggressiveness compared to its low-grade counterpart. Histopathological assessment plays a critical role in diagnosis, treatment decisions, and prognosis evaluation.
Analysis of Potential Hazards with Job Safety Analysis Techniques at Filling Stations and Transportation of Bulk LPG – PT. Tambang Yokodelta North Sulawesi Arikalang, Aprillya; Adam, Arlin; Sanuddin, Sudirman; Zamli, Zamli
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 2 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i2.1561

Abstract

Background: The LPG Bulk Filling and Transportation Station (SPPBE) at PT. Tambang Yokodelta Matungkas, North Minahasa, is a high-risk environment due to the flammable and pressurized nature of LPG. Identifying potential hazards is essential to ensure worker safety and prevent accidents. Objective: This study aims to analyze potential hazards and assess occupational risks using the Job Safety Analysis (JSA) method at the SPPBE of PT. Tambang Yokodelta. Methods: This qualitative research involved interviews and observations with eight informants, including the SPPBE manager, HSE head, technicians, and operators. Data were collected through interviews, field observations, and document review, and analyzed descriptively. Results: The study identified hazards classified into four risk levels: Low, Medium, High, and Extremely High. Low-risk activities, such as minor injuries, can be controlled with personal protective equipment (PPE). Medium risks, like falling during LPG handling, require additional PPE. High risks, including fire hazards during gas filling, need engineering controls. Extremely high-risk activities, such as gas explosions, require immediate management action and substitution measures. Conclusion: Workers at PT. Tambang Yokodelta face various risks. Effective control measures, including PPE, SOP compliance, engineering controls, and management commitment, are crucial for ensuring occupational safety.
Case Report: 60-Year-Old Female with Ischemic Stroke, Type 2 Diabetes Mellitus, and Hypertension Husnawati, Husnawati; Andriani, Dita Maulida; Rizki, Famella Yustika; Wanty, Fitri Prima; Sinaga, Giacinta Gracesandy; Rahmi, Helvy; Anggraini, Laurentin Leni; Khairani, Putri; Sakinah, Rezkila; Rasihen, Sri Lidya; Wahyudi, Wahyudi; Sinulinga, Yori Yunita
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 2 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i2.1564

Abstract

Background: Ischemic stroke remains a leading cause of death and disability worldwide, with increasing incidence each year. Patients with comorbidities, such as Type 2 diabetes mellitus (DM), pose additional treatment challenges due to a higher risk of drug-related problems (DRPs), particularly drug interactions. Objective: This study aims to describe pharmaceutical care in female patients diagnosed with ischemic stroke and Type 2 DM, with a focus on identifying and evaluating DRPs. Method: A descriptive case study was conducted. Data were collected through medical records and patient monitoring, focusing on the identification and analysis of potential DRPs in the context of pharmaceutical care. Results: The study found drug interactions as the most prominent DRP. An interaction between potassium slow-release (KSR) and candesartan was identified as requiring monitoring. Additionally, moderate interactions were found between atorvastatin and clopidogrel, as well as atorvastatin and amlodipine. These interactions have the potential to influence therapeutic outcomes. Conclusion: The prescribed medication regimen was generally appropriate for the patient's condition. Nevertheless, the presence of DRPs highlights the importance of regular monitoring and dose adjustments. Optimizing pharmaceutical care through early detection and management of DRPs is essential to ensure treatment safety and effectiveness in patients with complex conditions.
The Role of Tumor Budding as a Prognostic Factor in Colorectal Adenocarcinoma Rianti, Andi Marcha; Miskad, Upik Anderiani; Cangara, Muhammad Husni; Wahid, Syarifuddin; Achmad, Djumadi; Tawali, Suryani
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 1 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i1.1586

Abstract

Background: Colorectal cancer is one of the most prevalent malignancies worldwide. Tumor budding has emerged as a potential prognostic indicator in colorectal adenocarcinoma. Objective: This study aimed to analyze the relationship between tumor budding and histopathological grade, lymphovascular invasion, and lymph node metastasis in colorectal adenocarcinoma, and to assess the potential of tumor budding as a prognostic factor. Methods: A cross-sectional study was conducted using 93 colorectal adenocarcinoma samples. The association between tumor budding and histopathological grade, lymphovascular invasion, and lymph node metastasis was evaluated using the Chi-square and Mann-Whitney tests. Results: Among the 93 samples, a significant difference in tumor budding scores was found between cases with and without lymphovascular invasion (p = 0.003). However, no significant association was observed between tumor budding scores and histopathological grade (p = 0.685) or lymph node metastasis (p = 0.092). Additionally, a significant correlation was found between lymphovascular invasion and lymph node metastasis (p < 0.001). Conclusion: Tumor budding may serve as an important prognostic factor in colorectal adenocarcinoma, particularly in its association with lymphovascular invasion
Characteristics of ER, PR, HER2 and Ki67 Expression in Invasive Breast Cancer Patients at RSUP Dr. Wahidin Sudirohusodo, Makassar 2021-2023 Rahmawani, Surya; Nelwan, Berti J; Miskad, Upik Anderiani; Cangara, Muhammad Husni; Sungowati, Ni Ketut; Yamin, Amalia; Aslam, Muhammad; Mardiati, Mardiati
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 1 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i1.1589

Abstract

Background: Invasive breast carcinoma is the most common type of breast cancer among women globally, with high mortality. In Indonesia, it ranks first based on Globocan 2020 data. Objective: To determine the expression of prognostic and predictive markers—Estrogen Receptor (ER), Progesterone Receptor (PR), HER2, and Ki67—in breast cancer cases at RSUP Wahidin Sudirohusodo. Methods: A descriptive study was conducted on 71 samples from 2021–2023. Data on age, histopathologic grade, and marker expression (HER2, ER, PR, Ki67) were analyzed. Samples were stained and examined microscopically. Chi-square tests were performed using SPSS version 27. Results: Among the 71 samples, 47.89% were from patients aged < 50 years and 52.11% from those >/ 50. Grade 2 was most common (59.15%). HER2 expression was negative in 59.15% of samples, ER positive in 83.10%, PR positive in 67.61%, and Ki67 expression was low in 52.11%. Conclusion: Most cases showed negative HER2 and positive ER/PR expression with low Ki67, indicating the relevance of hormonal receptors and proliferation rate as prognostic indicators. These markers are crucial for prognosis and treatment planning in breast carcinoma.
The Relationship Between Fruit and Vegetable Consumption with The Incidence of Anemia Among Adolescent Girls in Three High Schools In Central Maluku Mailera, Damara Herlis; Asmin, Elpira; Abbas, Mutmainnah; Tahitu, Ritha; Titaley, Christiana Rialine; Seimahuira, Theresia
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 2 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i2.1591

Abstract

Background: Anemia is a global health problem common in both developed and developing countries, often caused by nutritional deficiencies, including low intake of fruits and vegetables. Adolescent girls are particularly at risk due to monthly menstrual blood loss. Objective: This study aimed to analyze the relationship between fruit and vegetable consumption and the incidence of anemia among adolescent girls in three high schools in Central Maluku in 2024. Methods: This was a quantitative analytical study using a cross-sectional design. The population consisted of students from SMA Negeri 15, SMA Negeri 44, and SMA Negeri 48 Central Maluku. A total of 102 respondents were selected using a total sampling technique. Anemia status was measured using the Hemocue device, and data on fruit and vegetable consumption were collected using the Commcare application. Data analysis was performed using the Spearman test. Results: The prevalence of anemia among respondents was 36.3%. Meanwhile, 63.7% reported regularly consuming fruits and 55.9% regularly consumed vegetables. Conclusion: There was no statistically significant relationship between fruit (p = 0.504) and vegetable (p = 0.587) consumption and the incidence of anemia in adolescent girls in the selected Central Maluku high schools in 2024.
The Characteristics of Conjunctivitis Patients at the Eye Hospital Makassar: A Recent Analysis of January – December 2023 Records M, A Alya Amaliah; Maharani, Ratih Natasha; Sodiqah, Yani; Akib, Marlyanti Nur Rahmah; Aulia, Nur; Hastiah, Hastiah
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 2 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i2.1596

Abstract

Background: Conjunctivitis is an inflammation of the conjunctiva caused by viruses, bacteria, fungi, or allergies, with varying prevalence based on etiology, age, gender, and season. Objectives: This study aims to determine the characteristics of conjunctivitis patients at the Makassar Eye Hospital from January to December 2023. Methods: This research employed a descriptive method with a retrospective approach using patient medical record data. The study included 118 conjunctivitis patients as the sample. Results: The most affected age group was 18–65 years (72%), followed by children (16.9%) and the elderly over 65 years (11%). Conjunctivitis was more prevalent in females (60.2%) than males (39.8%). The most common etiology was allergy (39%), followed by bacterial (31.4%) and viral causes (29.7%). Allergic conjunctivitis was primarily treated with artificial tears (30.4%) and antihistamines. Bacterial conjunctivitis was mainly managed with a combination of antibiotics, steroids, and artificial tears (43.2%). Viral conjunctivitis was also most frequently treated with the same combination therapy (40%). Conclusions: Conjunctivitis is most prevalent among individuals of productive age (18–65 years) and more common in females. Allergic conjunctivitis is the most frequent type, with artificial tears being the primary treatment.
Effects of Pear Juice on Weight Loss in Obese Adolescents Purnamasari, Yulia; Hikmawati, Isna; Amelia, Vivi Leona; Linggardini, Kris
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 2 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i2.1597

Abstract

Background: Adolescents are highly vulnerable to nutritional problems, with obesity recognized as a global epidemic by the World Health Organization (WHO). In Indonesia, around 13.5% of individuals over 18 are overweight, and 28.7% are obese. Objective: This study aimed to examine the effect of pear juice consumption on weight loss among obese adolescents. Methods: A quasi-experimental study with a pre-test and post-test control group design was conducted. Participants were divided into intervention and control groups, each with 34 obese adolescents selected through purposive sampling. Data were analyzed using Paired t-Test and Independent t-Test at a significance level of </ 0.05. Results: Most respondents were male (55.9%), 75.0% were classified as obese based on BMI, and 60.3% had a genetic predisposition to obesity. The intervention group showed an average weight loss of 1.91 +/ 0.332 kg, while the control group had an average weight gain of 1.79 +/ 0.155 kg. Although weight loss in the intervention group was significant, the difference between groups was not statistically significant. Conclusion: Pear juice may help reduce weight in obese adolescents, possibly due to its fiber content that supports calorie regulation. Further studies with larger samples are recommended.

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