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Jurnal Kedokteran Hewan
Published by Universitas Syiah Kuala
ISSN : 1978225X     EISSN : 25025600     DOI : 10.21157
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Veterinary
Jurnal Kedokteran Hewan (J. Kedokt. Hewan), or Indonesian Journal of Veterinary Sciences is a scientific journal field of veterinary sciences published since 2007, published FOUR times a year in March, June, September, and December by Universitas Syiah Kuala (Syiah Kuala University) and Indonesian Veterinary Medical Association (PDHI). Jurnal Kedokteran Hewan is a double-blind review process journal that has been accredited by National Journal Accreditation (ARJUNA), with second grade (Sinta 2), Number: 200 / M / KPTS / 2020. This journal has been registered in the Indonesian Publication Index (IPI), Google Scholar, Sinta, World Cat, Directory of Open Access Journals (DOAJ), EBSCO, Copernicus, Microsoft Academic, and other scientific databases. Jurnal Kedokteran Hewan receives scientific manuscripts in veterinary sciences (veterinary miscellaneous): anatomy, histology, physiology, pharmacology, parasitology, microbiology, epidemiology, veterinary public health, pathology, reproduction, clinic veterinary, aquatic animal disease, animal science, and biotechnology.
Arjuna Subject : Kedokteran Hewan - Kedokteran Hewan (Lain-Lain)
Articles 901 Documents
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THE SEDATIVE STUDY OF TABAR KEDAYAN ROOT ETHANOLIC EXTRACT (Aristolochia foveolate) IN MICE (Mus musculus) Wijayanti, Agustina Dwi; Nugroho, Alvinia Rusandriani; Yanti, Desti Ika; Fitriana, Ida ida
Jurnal Kedokteran Hewan Vol 18, No 2 (2024): June
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v18i2.33759

Abstract

The study was conducted to know the sedation effect of Tabar kedayan (Aristolochia faveolate). Thirty male mice were grouped into six groups, and each group contained five mice which were given six treatments. Group I, II, III, and IV were treated orally with tabar kedayan root ethanolic extract (TKREE) with a single dose of 50, 100, 200, and 400 mg/kg body weight, group V was given chlorpromazine with a dose of 20 mg/kg, and group VI was given distilled water 10 mL/kg of body weight. Based on the analysis, the results of mice falling time for group I, II, III, IV, V, and VI were 238.93101.01, 208.38115.41, 240.69102.19, 276.4268.28, 31.6464.55, and 168.09126.82 seconds, respectively. The groups were significantly different from the positive control group (P0.05). Mice treated with TKREE fell longer than negative and positive controls. Based on these results, the administration of TKREE did not cause a sedation effect on mice; otherwise, may have potential as a stimulant, and studies are needed to provide scientific evidence to support this potential.
ANGIOGENESIS ACTIVITY OF Chromolaena odorata L. LEAF EXTRACT GEL IN OPEN WOUNDS INCISION PHASE II OF RATS Limbong, Ahmad Affandi; Mirnasari, Mirnasari; Dasrul, Dasrul; Ismy, Jufriady; Hidayat, Imam; Yusuf, M
Jurnal Kedokteran Hewan Vol 18, No 2 (2024): June
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v18i2.36581

Abstract

This study aims to determine the effect of administering Chromolaena odorata L. leaf extract gel on increasing angiogenesis in the healing of open incisional wounds in rats (Rattus norvegicus). In this study, 27 healthy male rats, aged 3-4 months with a body weight of 150-200 g were used. The rats were anesthetized and incised in the back area with a size of 2x2 cm (WxL) and a depth reaching subcutaneous. The rats were divided into three groups (n= 9), the group only given gel (P0), the group of rats that were given 10% Chromolaena odorata leaf extract gel (P1), and the group of rats that were given 20% Chromolaena odorata leaf extract gel (P2). Collection of wound skin tissue samples for histopathological preparations was carried out on days 3, 7, and 14 after treatment, 3 individuals per group for each collection. The results showed that application of Chromolaena odorata leaf extract gel on P1 and P2 could increase angiogenesis significantly (P0.05) compared to P0 on days 3 and 7, but was not significantly different (P0.05) on day 14. The average angiogenesis in P1 and P2 on day 3 was similar, while on day 7 the average angiogenesis on P1 was significantly different compared to P2. It was concluded that administration of Chromolaena odorata leaf extract gel could increase angiogenesis in rats during phase II of the open incision wound healing process.
IDENTIFICATION OF QUANTITATIVE AND QUALITATIVE TRAITS DIVERSITY IN LOCAL BUFFALO IN NAGAN RAYA DISTRICT Abdullah, Mohd Agus Nashri; Mutawalli, Mutawalli; Ammar, Muhammad; Sari, Eka Meutia
Jurnal Kedokteran Hewan Vol 18, No 2 (2024): June
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v18i2.34229

Abstract

b-districts, Beutong and Seunagan, with 45 buffalo samples from each sub-district. The survey method with random buffalo sampling was employed in this study. The selection of the two research sub-districts was based on the highest buffalo population numbers in Nagan Raya District. The research locations were chosen from six villages: Babah Krueng, Gunong Nagan, Blang Seunong, Sapek, Alue Dodok, and Blang Pateuk. Primary data were obtained from measuring several quantitative traits of buffaloes aged 2.5-3.0 years in the field. All data were analyzed using descriptive statistics. The research results show that the quantitative traits based on the coefficient of variation (CV) of body measurements of buffaloes in Nagan Raya vary considerably. The body measurements of male buffaloes in Beutong Sub-District showed chest circumference, shoulder height, and body length of 172.70 cm, 121.84 cm, and 111.48 cm, respectively, while the female buffalo's chest circumference, shoulder height, and body length were 180.86 cm, 122.18 cm, and 119.32 cm, respectively. The body measurements of male buffaloes in Seunagan Sub-District showed chest circumference, shoulder height, and body length of 169.23 cm, 115.91 cm, and 105.23 cm, respectively, while the female buffalo's chest circumference, shoulder height, and body length were 187.89 cm, 123.04 cm, and 117.39 cm, respectively. The qualitative and quantitative traits of buffaloes measured in these two subdistricts show differences due to different environmental vegetation.
THE ACCURACY OF VAGINAL MUCUS CHARACTERISTICS AS CLINICAL SIGNS IN EARLY PREGNANCY DIAGNOSIS OF DAIRY CATTLE Suwandi, Syifa Damaianti; Supriatna, Iman; Setiadi, Mohamad Agus
Jurnal Kedokteran Hewan Vol 18, No 2 (2024): June
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v18i2.35615

Abstract

This study aims to observe the changes in the characteristics of vaginal mucus to diagnose early pregnancy in dairy cattle. The characteristics of vaginal mucus include pH value, consistency, volume, and Vaginal Electrical Resistance (VER) value to diagnose early pregnancy using a Draminski Estrous Detector. The sample used that collected in this research was 52 dairy cattle. The research method consists of taking samples and observing the characteristics of the mucus. Data analysis includes normality test, T-test and Pearson correlation. The results showed that the mucus volume of pregnant cattle was less (1.280.356 mL) than that of non-pregnant cattle (2.210.437 mL), the pH value in pregnant cattle tended to be acidic, while non-pregnant cattle were classified as neutral, and there were differences in the consistency of mucus in pregnant cattle (4.00.0), while non-pregnant cows tended to be liquid (2.60.204). The volume and consistency of vaginal mucus in pregnant and non-pregnant cattle were significantly different (P0.05). The VER value of pregnant cattle was higher (36563.2 ohms) than non-pregnant cattle (19055.3 ohms). The VER value was highly correlated (r= 0.819) with the pregnancy status of dairy cattle. Thus, VER can be used as an accurate indicator to determine the status of early pregnancy in dairy cattle.
THE QUALITY OF CHILLED RAM SEMEN AFTER STORAGE IN EXTENDER WITH ADDITION OF MELATONIN AT 4 C Triyaningrum, Triyaningrum; Fahrudin, Mokhamad; Karja, Ni Wayan Kurniani; Prasetyaningtyas, Wahono Esthi
Jurnal Kedokteran Hewan Vol 18, No 1 (2024): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v18i1.34649

Abstract

Semen was collected using an artificial vagina, and then examined macroscopically and microscopically. Semen with motility of 70% was diluted into different extenders: tris egg yolk-glucose (TEYG), tris egg yolk-glucose extender with 0.5 mM melatonin (TEYG + M0.5), tris egg yolk-glucose extender with 1 mM melatonin (TEYG + M1), tris egg yolk-glucose extender with 2 mM melatonin (TEYG + M2). All semen samples were stored at 4 C for 5 days (H0-H5) and examined every 24 hours. Semen was examined for spermatozoa motility, viability, abnormality, and membrane plasma integrity. The results showed that there were no significant changes of semen quality on H0 (P0.05). In general, the melatonin supplemented groups had a higher semen quality value than the control. Melatonin supplementation can protect and maintain the quality of chilled semen. In addition, the result showed that TEYG + M1 extender was the best extender treatment, which was indicated by higher values than other treatments.
PHYSICO-CHEMICAL VALUE AND HYPOGLYCEMIC EFFECT OF INDUSTRIAL-GRADE ETHANOLIC EXTRACT OF PIGEON PEA (Cajanus cajan) LEAVES AND GINGER (Zingiber officinale var. amarum) Wresdiyati, Tutik; Alfarisi, Hamzah; Putri, Anisya Saeila; Abidah, Puri Adzrok; Darawati, Made; Aziz, Sandra; Sadiah, Siti; Astawan, Made; Santoso, Koekoeh
Jurnal Kedokteran Hewan Vol 18, No 1 (2024): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v18i1.31691

Abstract

This study aimed to analyze flavonoid and 6-gingerol content and to test the hypoglycemic effects of industrial-grade Cajanus cajan (pigeon pea) leaf and Zingiber officinale rhizome (ginger) extracts on hyperglycemic rats. Extraction utilized maceration with 70% alcohol at PT. Insular Multi Natural. Extracts were characterized and analyzed for flavonoids and 6-gingerol content. Hypoglycemic activity was assessed using the oral glucose tolerance test (OGTT) on rats with induced hyperglycemia via 90% sucrose solution. The results indicated higher flavonoid content in C. cajan leaf extract (4090.09338.23 mg/100 g) compared to Z. officinale extract (622.74203.39 mg/100 g), while gingerol content in Z. officinale extract was 701.524.42 mg/100 g. This study concluded that combination of industrial-grade pigeon pea leaves extract and ginger extract reduce the level of blood glucose in hyperglycemic model rats at all combination dose (150:150, 200:100, and 100:200 mg/kg BW). The combination dose of 200:100 mg/kg BW showed the best blood glucose level profile.
THE EFFECT OF SUPEROVULATION INDUCTION USING FSH ON INCREASING FSH AND LH CONCENTRATIONS IN NEW ZEALAND WHITE RABBITS Wahyuni, Sri; Fathurrahman, Fadhil; Adam, Mulyadi; Syafruddin, Syafruddin; Roslizawaty, Roslizawaty; Hasan, Muhammad; Melia, Juli; Dasrul, Dasrul; Isa, Muhammad; Rosmaidar, Rosmaidar
Jurnal Kedokteran Hewan Vol 18, No 1 (2024): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v18i1.37513

Abstract

This study aimed to determine the concentrations of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH) in New Zealand White (NZW) rabbits after superovulation induction using FSH. Six female NZW rabbits and one male NZW rabbit were used in this study. Criteria for female NZW rabbits used include having previously given birth, not being pregnant, and having a body weight of 2-3 kg. The rabbits were divided into two treatment groups; the first group was injected with physiological NaCl (NZW1, n= 3), while the second group was injected with FSH (NZW2, n= 3). Injections of physiological NaCl or FSH were administered five times at 12-hour intervals and first injection was given at 20:00 p.m. In NZW1, each injection was given physiological NaCl with volumes of 0.2:0.2+0.2;0.4+0.4 mL, respectively whereas in NZW2, each injection was given FSH with doses of 4:4+4:8+8 mg, respectively. Twelve hours after the last FSH injection, NZW2 rabbits were injected with 100 IU hCG and mated with male rabbit, while NZW1 rabbits were mated without hCG administration. On days 1, 3, and 5 after mating, blood samples were collected for FSH and LH hormone examination using the Enzyme-Linked Immunosorbent Assay (ELISA) method. The FSH concentrations on days 1, 3, and 5 between NZW1 vs NZW2 were 34.781.46 vs 39.753.18; 41.434.90 vs 41.425.14; and 44.471.51 vs 30.130.19 mIU/mL, respectively (P0.05). The LH concentrations on days 1, 3, and 5 between NZW1 vs NZW2 were 33.784.01 vs 40.1812.36; 29.342.24 vs 31.3110.13; and 42.0911.38 vs 30.578.87 mIU/mL, respectively (P0.05). It is concluded that FSH administration does not affect the concentrations of FSH and LH in NZW rabbits. The FSH concentration five days after mating tends to fluctuate, while the LH concentration tends to decrease as the days increased.
ANALYSIS OF THE ACUTE IMMUNE RESPONSE OF PACIFIC WHITE SHRIMP (Litopenaeus vannamei) INFECTED BY Vibrio parahaemolyticus AND ITS METABOLITES Rahayu, Indar Widiastuti; Rizkiantino, Rifky; Halalludin, Beni; Herman, Roffi Grandiosa; Dewanti, Lantun Paradhita; -, Iskandar; Wisoyo, Daniel; Sari, Putri Purnama; Rahayu, Mufti; Fitriana, Rachmawati Nur; Panjaitan, Bestran Virlando; Haliman, Rubiyanto Widodo; Laiman, Hendri
Jurnal Kedokteran Hewan Vol 18, No 1 (2024): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v18i1.34498

Abstract

This study was aimed to observe the survival rate (SR) and clinical signs, and the acute immune response of Pacific white shrimp (Litopenaeus vannamei), including total hemocyte count (THC), bacterial clearance, and prophenoloxidase (ProPO) activity due to infection with the Vibrio parahaemolyticus bacteria and its metabolites. Shrimp were infected by bacterial isolates with culture media (A), bacterial isolates without culture media (B), and metabolites suspensions from bacterial culture media (C) for 8 hours with observation every 2 hours. The results showed that experimental shrimps in groups A and B showed clinical signs and reduced SR, 24.44% and 62.22%, respectively. Experimental group C still showed the clinical signs but did not cause the mortality (SR 100.00%). The THC did not show significant changes, either based on experimental groups or duration of infection, but all groups tended to show decreasing THC at 8 hours post-infection. Bacterial clearance and ProPO activity also did not show significant differences between experimental groups or duration of infection at 8 hours post-infection. However, there was an increase in bacterial clearance activity at 6 hours post-infection in the experimental groups A and B. Based on the study results, the acute immune response in shrimp from all of the experimental groups did not show significant changes at 8 hours post-infection. However, group A significantly decreased SR compared to groups B and C.
EFFECT OF CIPLUKAN STEMS AND LEAVES EXTRACT ADMINISTRATION (Physalis angulata L.) ON THE DEGREE OF hepatic lobes INFLAMMATION IN DYSLIPIDEMIA INDUCED WISTAR RATS Safira, Nazala; Pamungkas, Katon; Utami, Rizki fajar; Ahsani, Dwi Nur; Pramaningtyas, Miranti Dewi
Jurnal Kedokteran Hewan Vol 18, No 1 (2024): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v18i1.32339

Abstract

The aim of this study was to determine the effect of stems and leaves ciplukan extract on the degree of liver lobe inflammation in dyslipidemia-induced wistar rats. This research was an experimental study with a post-test only design. A total of 24 Wistar rats were allotted into 4 groups with 6 rats per group. Hepatic organs were then histologically stained with Hematoxylin-Eosin stain. Inflammation reading was done by looking for inflammatory foci in the preparation. The result was then analyzed using Kruskal-Wallis test. The results showed that groups I and II had one severe inflammation. Group III had two severe degrees of inflammation. Group IV had no severe inflammation. The analysis revealed that there was no significant difference in the degree of inflammation between groups (P= 0.964). Administration of ciplukan stem and leaf extract did not affect the degree of liver lobe inflammation in Wistar rats induced by dyslipidemia.
THE EFFECTIVENESS OF COMBINATION OF SNAKEHEAD FISH, TEMULAWAK, AND MENIRAN EXTRACTS ON POST OVARIOHYSTERECTOMY WOUND HEALING IN CATS Bermani, Fadeli; Soehartono, Raden Harry; Berlian, Guntur; Siswandi, Riki
Jurnal Kedokteran Hewan Vol 18, No 1 (2024): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v18i1.34542

Abstract

This study aims to determine the effectiveness of combination of snakehead fish, ginger and meniran extract (GTM) on healing wounds after ovariohysterectomy (OH) in cats. Twenty healthy female cats aged 1-4 years, weighed 2-4 kg were divided into three groups with different doses of GTM and compared with the group without treatment (n= 5 cats/group). The GTM dose was extrapolated from the human dose using allometric scaling, with the basal dose for G:T:M were 40:3.2:4.8 mg/kg BW (group 1, GTM1x). Treatment groups 2 (GTM2x) and 3 (GTM4x) were given a dose of GTM that was multiplied by 2 and 4 of the basal doses, respectively. OH was performed via a flank approach with the same operator and anesthesia. Discharge, swelling and erythema scores were significantly lower on days 3, 4 and 5 post-operativeamong all GTM groups compared with control. Pain evaluation using Baseline Tactile Semmes Monofilaments showed significantly lower in GTM2x and GTM4x compared to GTM1x and control. The 4A-vet pain scale showed lower pain in GTM2x from 1 to 5 days postoperative. The number of leukocytes, erythrocytes and platelets was in the normal range indicates the absence of postoperative infection. Postoperative albumin levels showed a significantly higher difference in GTM2x compared to control. The treatment given GTM2x showed the fastest healing interval (3.20.44 days). The combination of GTM can reduce pain, reduce wound scores and accelerate post-OH wound healing with the most effective dose was GTM2x. ________________________________________________________________

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