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INDONESIA
Jurnal Kedokteran Hewan
Published by Universitas Syiah Kuala
ISSN : 1978225X     EISSN : 25025600     DOI : 10.21157
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Veterinary
Jurnal Kedokteran Hewan (J. Kedokt. Hewan), or Indonesian Journal of Veterinary Sciences is a scientific journal field of veterinary sciences published since 2007, published FOUR times a year in March, June, September, and December by Universitas Syiah Kuala (Syiah Kuala University) and Indonesian Veterinary Medical Association (PDHI). Jurnal Kedokteran Hewan is a double-blind review process journal that has been accredited by National Journal Accreditation (ARJUNA), with second grade (Sinta 2), Number: 200 / M / KPTS / 2020. This journal has been registered in the Indonesian Publication Index (IPI), Google Scholar, Sinta, World Cat, Directory of Open Access Journals (DOAJ), EBSCO, Copernicus, Microsoft Academic, and other scientific databases. Jurnal Kedokteran Hewan receives scientific manuscripts in veterinary sciences (veterinary miscellaneous): anatomy, histology, physiology, pharmacology, parasitology, microbiology, epidemiology, veterinary public health, pathology, reproduction, clinic veterinary, aquatic animal disease, animal science, and biotechnology.
Arjuna Subject : Kedokteran Hewan - Kedokteran Hewan (Lain-Lain)
Articles 901 Documents
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EFFECTIVENESS OF STEM CELL THERAPY IN MYOCARDIAL INFARCTION BASED ON ENZYME ACTIVITY AND LIVER HISTOPATOLOGY Rahmi, Riska Asria Sa'adatur; Gunanti, Gunanti; Noviana, Deni; Harlina, Eva
Jurnal Kedokteran Hewan Vol 18, No 4 (2024): December
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v18i4.30881

Abstract

This research aims to study the effectiveness of single placenta stem cell therapy (ST) or a combination of cardiomyocyte co-cultures in pigs with myocardial infarction based on enzymes alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activity as well as liver histopathology. Nine pigs were divided into three treatment groups (K1, K2, and K3) consisting of three pigs per group. Blood sampling was performed one-hour pre-surgery, post-ST-elevation, and eight weeks post-therapy. The experimental animals were treated for eight weeks, then euthanized and necropsied for liver removal. ALT and AST values were analyzed using one-way analysis of variance (ANOVA) and followed by Tukey's test. Histopathological changes in liver tissue were analyzed using Image J 1.53 software, and the measured data were analyzed using oneway ANOVA. The results showed an increase in the ALT and AST values of the three treatment groups on post-ST-elevation blood sampling but were still within normal limits except for K1. ALT and AST values decreased significantly (P0.05) in the group treated with single placental stem cell (K2) or combined cardiomyocyte co-culture (K3). The ALT value of K3 decreased but not significantly (P0.05) compared to K2. The AST value of K3 decreased significantly (P0.05) but was not significantly different (P0.05) compared to K2. The liver tissue showed circulatory disturbances in the central venous congestion, portal vein, sinusoidal dilatation and congestion, and hepatocyte changes in the form of centrilobular necrosis and hydropic degeneration. Stem cell therapy alone (K2) or in combination with cardiomyocyte co-culture (K3) had similar percentage of centrilobular necrosis which was significantly lower than K1 (P0.05). Hepatocyte hydropic degeneration on K2 was classified as mild, whereas on K3 was classified as moderate. As conclusion, administration of placental stem cell therapy alone or in combination with cardiomyocyte co-culture can reduce ALT and AST values and could repair liver tissue.
EFFECTIVENESS OF SUGAR DRESSING TREATMENT OF LAWANG SUGAR CANE ORIGIN ON INCISIONS WOUND HEALING OF RABBIT SKIN Rezeki, Sri; Gunanti, Gunanti; Subangkit, Mawar
Jurnal Kedokteran Hewan Vol 18, No 3 (2024): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v18i3.33524

Abstract

The aim of this research was to determine the effectiveness of sugar dressing treatment from Lawang sugar cane on incision wound healing process of rabbit skin. Nine New Zealand white rabbits were divided into three treatment groups with three rabbits per group. In negative control group (KN), the wounds were only treated with distilled water, while in SD60 and SD100 groups, the wounds were treated with 60% and 100% sugar solution, respectively. The treatment was given once daily for 7 days. The results showed that the sugar dressing treatments have significant effect (P0.05) on the size of the wound area and increased the collagen density, but did not have significant effect on the remaining length of the wound.Based on the results of the study, it can be concluded that sugar dressing dressing treatment from Lawang sugar cane is effective in increasing collagen density in the wound healing process.
RELIABILITY OF AMYLOID DETECTION IMMUNOASSAY KITS FOR ALZHEIMERS DISEASE SCREENING: A PRELIMINARY STUDY Putri, Indah Aprianti; Ningrum, Emilna Mega; Noviana, Rachmitasari; Mariya, Silmi; Saepuloh, Uus; Retnani, Elok Budi; Hamdan, Muhammad; Nugraha, Jusak; Darusman, Huda Shalahudin
Jurnal Kedokteran Hewan Vol 18, No 3 (2024): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v18i3.31109

Abstract

Alzheimers Disease is a progressive neurodegenerative disease that damages the brain and is part of dementia. Alzheimers dementia is caused by various factors that until now the proper therapy is uncertain. Kit production as a diagnostic tool to support the development of screening for Alzheimers disease is a strategic effort. Screening based on detection with Enzyme-Linked Immunosorbent Assay (ELISA) can work effectively and accurately to optimize a specific antibody material or monoclonal antibody to the A42 peptide. This study aimed to research the reliability of the amyloid detection kit which was developed as an alternative screening test for Alzheimers disease compared to commercially available kits. Based on the results and interpretation of inter and intra-assay coefficients, the in-house ELISA kit has comparable A42 detection to the commercially available ELISA kit
PREVALENCE AND RISK FACTOR OF HAEMONCHUS CONTORTUS IN LAKOR GOAT IN LAKOR DISTRICT SOUTHWEST MALUKU Sukariada, I Putu Juli; Ludji, Sherli Melani; Noach, Steffanie M. C.; Puspitayani, Putu Mira
Jurnal Kedokteran Hewan Vol 18, No 4 (2024): December
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v18i4.32681

Abstract

The aimed of this research is to determine the prevalence of Haemonchus. contortus and the associated risk factors. In this study, 739 fecal samples from Lakor goats were randomly collected from five villages in Lakor District, Southwest Maluku. All samples were taken from goats showing clinical symptoms such as emaciation, diarrhea, dull fur, and inactive. Fecal samples were examined using the native method. Data presentation was analysed using the Chi-Square (X2) and Spearman's test statistical analysis methods. The prevalence of H. contortus in Lakor goats in the Lakor sub-District was 81.60% with the highest prevalence was found in Yamluli Village and Lolotuara Village. The correlation coefficient was 0.838** - 0.931** (P0.01). These data indicated that there is a close relationship between the incidence of H. contortus worm infection in lakor goats and the risk factors in the form of gender, age of the goat and body score condition (BCS) as indicated by the high correlation values.
LASER ACUPUNCTURE AS A NON-INVASIVE STRATEGY TO OPTIMIZE RABBIT GROWTH: HISTOMORPHOMETRIC AND LEUCOCYTE ANALYSIS STUDY Ritonga, Mudhita Zikkrullah; Hasan, Denny Irmawati; Hidanah, Sri; Lokapirnasari, Widya Paramita
Jurnal Kedokteran Hewan Vol 18, No 4 (2024): December
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v18i4.42593

Abstract

This study evaluates the effects of laser acupuncture on jejunum morphometry and the differential leucocyte responses in rabbits. Twenty-four Hycole rabbits, aged four to twelve weeks with an average weight of 1046 g, were administered laser acupuncture once a week for six weeks. The rabbits were housed in individual cages and randomly divided into three groups. Group 1 (control) received inactive laser acupuncture for predetermined acupuncture points (Bladder 13, Bladder 15, and Bladder 21). Group 2 received active laser acupuncture at the exact points BL 13, BL 15, and BL 21, using a laser dose of 0.2 Joules. Group 3 received laser acupuncture near, but not precisely at, these exact points. Blood samples were collected at the end of the 12th week, and the jejunum was excised for histomorphometric analysis. The results indicated that rabbits in group 2 had significant increases (P0.05) in villus height (VH), and villus width (VW) compared to groups 1 and 3. The results of differential leucocytes measurements in groups 1, 2, and 3 were lymphocytes 64.2037%, 61.80.374%, 61.80.489% (normal: 30-85%); monocytes 130.447%, 12.20.374%, and 13.40.244% (normal: 4-13.4%), granulocytes 23.40.748%, 260.447%, and 24.80.374 (normal: 21-73%), respectively. These findings indicate that laser acupuncture targeted at BL13, BL15, and BL21 points promotes villi development and maintains differential leukocyte parameters within the normal range.
DETECTION OF MULTIDRUG-RESISTANT Klebsiella pneumoniae IN THE UPPER RESPIRATORY TRACT OF BROILERS AND LAYER CHICKENS FROM COMMUNITY FARM IN ACEH BESAR, INDONESIA Darniati, Darniati; Erina, Erina; Abrar, Mahdi; Zainuddin, Zainuddin; AK, M Daud
Jurnal Kedokteran Hewan Vol 19, No 2 (2025): June
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v19i2.45844

Abstract

This study aimed to investigate the presence of multidrug-resistant (MDR) Klebsiella pneumoniae in upper respiratory tract of broiler chickensand laying hens from community farms in Aceh Besar. Tracheal swab samples were collected and cultured on eosin methylene blue agar for bacterialisolation. Suspected isolates were identified through biochemical testing and confirmed via PCR targeting the rpoB gene. Identified isolates weretested for antibiotic susceptibility against ciprofloxacin, tetracycline, gentamicin, erythromycin, and chloramphenicol, using the disc diffusionmethod. The results revealed K. pneumoniae in 6% of broiler and 14% of laying hens, with widespread multidrug resistance. All isolates wereresistant to erythromycin (100%), gentamicin (100%), tetracycline (85%), ciprofloxacin (40%), and chloramphenicol (15%). These findingsconcluded that there has been the spread of MDR of K. pneumoniae in broiler chickens and laying hens within Aceh Besars community farms inAceh Besar, Indonesia.
COMPUTER-ASSISTED SPERM ANALYSIS OF SPERM MOTILITY DYNAMICS IN GAGA ROOSTERS AT DIFFERENT AGES Khaeruddin, Khaeruddin; Junaedi, Junaedi; Sawitri, Wiwied
Jurnal Kedokteran Hewan Vol 19, No 2 (2025): June
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v19i2.44929

Abstract

This study aimed to evaluate the motility and kinematic parameters of Gaga chicken sperm at different ages using Computer-Assisted Sperm Analysis (CASA). Semen samples were collected seven times each from two roosters aged 6 months (young) and 12 months (mature) using the massage method. CASA evaluation assessed multiple parameters total motility, progressive motility, slow, static, distance average path (DAP), distance straight line(DSL), distance curvilinear (DCL), velocity average path (VAP), velocity straight line (VSL), velocity curvilinear (VCL), straightness (STR), linearity (LIN), amplitude of lateral head displacement (ALH), beat cross frequency (BCF), and wobble (WOB). Data were analyzed using an independent samples t-test. The results showed significant differences (P0.05) in progressive motility, DCL, VAP, and VCL between the two age groups, with the 12-month-old rooster showing higher values compared to the 6-month-old. In conclusion, the significantly higher sperm concentration and viability observed in mature roosters in this study underscore the importance of age-related reproductive maturity in optimizing semen quality for breeding purposes.
ASSESSING ELECTRICAL RESISTANCE OF VAGINAL MUCUS (ERVM) SCORES IN ESTRUS PHASE OF ACEH COWS AND THEIR ASSOCIATION WITH ESTROGEN AND PROGESTERONE LEVELS Thasmi, Cut Nila; Husnurrizal, Husnurrizal; Melia, Juli; Agung, Nabilah Putroe; Riady, Ginta; Yusuf, M.; Rosmaidar, Rosmaidar; Sayuti, Arman; Hasan, M.; Nazaruddin, Nazaruddin; Hafizuddin, Hafizuddin; Nurliana, Nurliana
Jurnal Kedokteran Hewan Vol 19, No 2 (2025): June
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v19i2.44940

Abstract

This study aimed to determine the correlation between ERVM scores and the levels of estrogen and progesterone in Aceh cows during estrus.This study utilized 8 clinically healthy Aceh cows aged 3-5 years. ERVM scores were determined using a DraminskiTMestrus detector probe insertedinto the vagina on the first day of estrus. Estrogen and progesterone concentrations were measured in blood samples collected on the first day of estrususing the enzyme-linked immunosorbent assay (ELISA) method. Data on the correlation between ERVM scores and the levels of estrogen andprogesterone concentrations were analyzed using the Pearson correlation test. The results showed that the average ERVM score during the estrusphase was 192.9216.94 , and the average concentrations of estrogen and progesterone were 103.1344.86 pg/mL and 0.960.60 ng/mL,respectively. Correlation analysis revealed that coefficient correlation (r) values between EVRM and estrogen was -0.607 and with progesterone was-0.149. In conclusion, the ERVM score in Aceh cattle indicates moderate estrus, and the ERVM score obtained in this study is negatively correlatedwith estrogen and progesterone concentrations.
SEROLOGICAL DETECTION OF BOVINE LEPTOSPIROSIS IN SUKABUMI AND CIANJUR REGIONS Susanti, Susanti; Rachmawati, Faidah; Mulyadi, Andi; Sukatma, Sukatma; Purba, Hastuti Handayani S; Anastasia, Yessy; Ariyanti, Tati; Prihandani, Sri Suryatmiati
Jurnal Kedokteran Hewan Vol 19, No 1 (2025): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v19i1.33751

Abstract

This study aims to detect leptospirosis serologically and serovars found in cattle in the Sukabumi and Cianjur areas. 165 cattle serum samples were taken randomly in the Sukabumi and Cianjur region. Microscopic Agglutination Tests (MAT) were used for serological testing using the antigens of Leptospira serovar Icterohaemorrhagiae, Javanica, Celledoni, Canicola, Ballum, Pyrogenes, Cynopteri, Rachmati, Australis, Pomona, Grippotyphosa, Hardjo, Bataviae, and Tarassovi. The MAT results showed that positive serum leptospirosis in cattle in Sukabumi region was 18.75%, with serovars Hardjo 16.25%, Tarassovi 1.25%, and Hardjo and Tarassovi (1.25%). Meanwhile, in Cianjur region, positive serum was 30.60% with serovar Hardjo 22.35%, Tarassovi 2.35%, Icterohaemorrhagiae 1.18%, Grippotyphosa 1.18%, Hardjo and Tarassovi 1.18%, Cynopteri and Hardjo (1.18%), Rachmati, Pomona, Bataviae and Tarassovi (1.18%). Leptospira serovar Hardjo was the dominant serovar in both regions. Overall, one serovar was detected in 22.42% of cattle, two serovars in 1.82% and four serovars in 0.61% cattle.
EFFECTIVENESS OF STINGLESS BEE HONEY IN INCREASING COLLAGEN IN THE SKIN WOUND HEALING OF RATS Maulana, M Ridha; Gunanti, Gunanti; Subangkit, Mawar
Jurnal Kedokteran Hewan Vol 19, No 1 (2025): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v19i1.44574

Abstract

The purpose of this study was to determine the effectiveness of stingless bee honey in healing incision wounds on rat skin based on collagen formation. A total of 30 Sprague-Dawley rats were divided into 3 observation days (n= 10 rats). The incisions performed on all rats but given different treatments. In negative control group, the incision wound was not treated, while in positive control, the incision was treated with bioplacentom. Rats in treatment 1 and treatment 2, the incision wound were treated with 75% and 100% stingless bee honey treatment was given once a day for 7 days. The results showed that the 75% and 100% stingless bee honey groups showed a significant effect on reducing the wound length and increasing the collagen density (P0.05). As conclusion, stingless bee honey is effective in increasing collagen density in the wound healing process of rat.

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