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The Effect of Propolis Trigona sp. Water Extract from North Lombok on Blood Sugar Levels in Vivo Ananta, Muhammad Naufal Farras; Nuralyza, Imasayu; Humaira, Ani Fatin; Sausan, Salwa; Hidayat, Lalu Husnul; Hasina, Raisya; Pratama, Iman Surya; Andayani, Yayuk; Aini, Siti Rahmatul
Jurnal Penelitian Pendidikan IPA Vol 10 No 8 (2024): August
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i8.7459

Abstract

Propolis has been touted for its ability to regulate blood sugar levels in diabetes, but the effectiveness can vary depending on the region. A study was conducted to investigate the effect of propolis Trigona sp. water extract on blood sugar levels in vivo. The mice were divided into three groups, with four mice in each group. The positive control group received a 5 mg/kgBW glibenclamide suspension, the negative control group was given a 0.25% CMC-Na suspension, and the treatment group was administered with water extract of propolis at a dose of 300 mg/kgBW. All groups were induced with a 20% D-glucose solution intraperitoneally, and blood sugar levels were measured at 15, 30, 60, 90, and 120 minutes via the tail vein. The blood sugar data was analyzed and presented descriptively. The Mann-Whitney statistical analysis was used to determine the results, revealing that the water extract of propolis at 300 mg/kgBW did not have a significant effect on reducing blood sugar levels in animals induced by a 20% D-glucose solution, with a significance value (p < 0.05).
Investigating the Phytochemical Composition, GCMS Profile and Antimicrobial Effects of Nursehan Herbal Remedy for Sinusitis in Praya, Central Lombok Agrijanti; Kusumadewi, Lale Budi; Khusuma, Ari; Djannah, Fathul; Aini, Siti Rahmatul
Jurnal Penelitian Pendidikan IPA Vol 11 No 11 (2025): November: In Progress
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i11.11125

Abstract

Recent studies emphasize the importance of medicinal plants in Indonesia's healthcare systems, where traditional remedies, including herbal formulations, are commonly used for treating ailments such as sinusitis. This research focuses on the Nursehan herbal remedy, a traditional treatment for sinusitis, used in Praya District, Central Lombok Regency. Nursehan is a combination of several plant materials, including Cinnamomum verum, Nauclea orientalis, and Nigella sativa, which are believed to alleviate sinus-related symptoms. However, scientific evidence supporting its efficacy remains limited. This study aims to validate the antimicrobial potential of Nursehan by analyzing its phytochemical profile and antibacterial activity. The Nursehan extract was prepared using a maceration method, and its chemical composition was assessed via GC-MS analysis, which identified key bioactive compounds such as hexadecanoic acid and 8-heptadecenoic acid, known for their antimicrobial and anti-inflammatory properties. Antimicrobial testing using the Kirby-Bauer method revealed significant antibacterial activity, particularly against Streptococcus pyogenes and Staphylococcus aureus. These findings provide scientific backing for the traditional use of Nursehan and highlight its potential as a therapeutic agent for sinusitis.