Article Per Year (5 Year)
p-Index From 2021 - 2026
10.427
P-Index
This Author published in this journals
All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan JURNAL GIZI INDONESIA Jurnal Kedokteran Brawijaya Althea Medical Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Medika Malahayati MEDIC MEdical Dedication Medical Scope Journal (MSJ) Jurnal RSMH Palembang Jurnal Karya Abdi Masyarakat Electronic Journal Scientific of Environmental Health And Diseases Gema Lingkungan Kesehatan Journal of Medical Studies Quantum Wellness : Jurnal Ilmu Kesehatan ASSYIFA: Jurnal Ilmu Kesehatan Medika Tadulako: Jurnal Ilmiah Kedokteran Fakultas Kedokteran International Journal of Health Science
Erny Kusdiyah
Universitas Jambi
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

Published : 85 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : Althea Medical Journal

 1 
Profile of Apoptotic Marker Genes and Histopathology of the Placenta in Pregnancies with Pre-Eclampsia Herlambang, Herlambang; Enis, Rina Nofri; Tarawifa, Susan; Harahap, Huntari; Puspasari, Anggelia; Maharani, Citra; Kusdiyah, Erny
Althea Medical Journal Vol 10, No 2 (2023)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v10n2.3088

Abstract

Background: Pre-eclampsia (PE) is a hypertensive disorder in pregnancy and a significant cause of maternal and perinatal mortality and morbidity. Failure of spiral artery remodeling due to abnormal apoptosis, triggers disturbances in the mother and the baby’s growth. This study aimed to identify the profile of apoptotic marker genes and histopathological features of the placenta in pregnancies with pre-eclampsia.Methods: This study had used case-control method. Samples were taken from normal pregnancies (n=25) and pregnant women with pre-eclampsia (n=25) using a purposive sampling method from several hospitals in Jambi. qRT-PCR was used to examine apoptotic gene expression from placental tissue and hematoxyline eosin staining to view the placenta’s microscopic appearance. The targeted genes were BCL2-associated X (BAX) and B-cell lymphoma 2 (BCL-2). Histopathological changes of the placenta observed were syncytial node, cytotrophoblast, villous edema, hypervascularization, fibrosis stroma, atherosis, infarction, and thrombosis.Results: Relative BAX genes expression were increased once in placenta pre-eclampsia compared to controls, but not statistically significant (p-value>0.05). There was no difference between the decline of BCL-2 gene expression in pre-eclampsia placenta compared to the control (p-value >0.05). Histopathological changes in the placenta were syncytial node and cytotrophoblast (25 of 25), villous edema (19 of 25), hypervascularization (24 of 25), fibrosis stroma (22 of 25), atherosis (12 of 25), infarction (17 of 25), and thrombosis (24 of 25).Conclusion: The expression of BAX genes in pre-eclampsia tends to increase compared to normal pregnancy, and the expression of BCL-2 decreases.  The histopathological features of pre-eclampsia pregnancy placenta are mostly syncytial nodes, cytotrophoblasts, stromal fibrosis, and thrombosis.
Protein Insufficiency Among First-Trimester Pregnant Women in Jambi, Indonesia Herlambang, Herlambang; Puspasari, Anggelia; Maharani, Citra; Enis, Rina Nofri; Fitri, Amelia Dwi; Kusdiyah, Erny; Ibnu, Ismi Nurwaqiah
Althea Medical Journal Vol 12, No 2 (2025)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v12n2.4044

Abstract

Background: Insufficient protein intake or specific patterns of plasma amino acid levels during pregnancy has been associated with adverse maternal and neonatal outcomes. Studies in non-pregnant women have reported an association between protein intake and amino acid levels, however, data in pregnant women remain limited. Jambi, a region rich in freshwater fish, has a traditional dishes based on fish, which may affect maternal protein adequacy. This study aimed to assess protein sufficiency intake, plasma essential amino acid levels, and the relationship between fish consumption and protein intake among first-trimester pregnant women. Methods: A cross-sectional study was conducted in 2022 involving pregnant women at 9-16 weeks of gestation in Jambi, Indonesia, selected through purposive sampling. Protein intake and fish consumption data were collected using Food Frequency Questionnaires. Plasma essential amino acid levels were measured using Liquid Chromatography-Mass Spectrometry. Bivariate analyses were performed using Mann-Whitney and Chi-square tests.Results: Among 30 participants, 23.3% had insufficient protein intake and had lower plasma essential amino acid levels. Lysine levels showed a statistically significant difference between groups (p=0.010). Women with adequate protein intake reported significant higher fish consumption, particularly of freshwater fish (p=0.033).Conclusion: Adequate protein intake during early pregnancy is related to higher plasma essential amino acid levels. Consumption of local freshwater fish contributes to maintaining sufficient protein intake. These findings emphasize the importance of integrating healthy dietary patterns and locally sourced nutrient-rich foods into prenatal care to support maternal wellness and long-term health outcomes.
Co-Authors Agung Prasetio ahmad syauqi, ahmad Ahmad Syauqy Ahmad Syauqy Ahmad Syauqy Amalia, Fenny Amatullah, Afifah Ameli Dwi Fitri Amelia Dwi Fitri Amelia Dwi Fitri Amelia Dwi Fitri Amelia Dwi Fitri Amelia Dwi Fitri Amelia Dwi Fitri, Amelia Dwi Amelia, Wulan Rizky Anati Purwakanthi, Anati Andika Sulistiawan Anggelia Puspasari Annissa Delfira Aras, Rudi Berlian Panji Arini Putri Antika Armaidi Darmawan Asro Hayani Harahap Asro Hayani Harahap Asro Hayani Harahap Asro Hayani Harahap Attiya Istarini Ave Olivia Rahman Azairin, Laura Prima Azzahra Sarah Fatimah Ramadhanti Budi Justitia Budi Justitia Cicilia Nopita Citra Maharani Delfira, Annisa dewi, hasna Dhea Assyifa Dianisa, Giva Ega Benita Elfiani Eliezer, Victor Elvi Roza Enis, Rina N. Erina Shinta Anggraini Esa Indah Ayu, Esa Indah Essy Octavia Fadillah, Tanty Fadli Fadli Faila Sufa Fairuz Quzwain Fairuz, Fairuz Fakhri, Ayushia Generosa Fatimah, Firda Firmansyah Firmansyah Firmansyah Firmansyah Firmansyah Gading, Patrick William Guspianto Guspianto Hanina Harahap, Asro Hayani Hasibuan, Mhd Usni Zamzami Hasmita, Debby Herlambang Herlambang Herlambang Herlambang HERLAMBANG HERLAMBANG Herlambang Herlambang Hiratna, Hiratna Hulwa Atika Adilita Humaryanto Humaryanto, Humaryanto Huntari Harahap Ima Maria indah ayu dia, Esa Intan Karnina Putri Iskandar, Mirna Marhami Ismi Nurwaqiah Ibnu Kashmir, Arifin Kurniawan Keisya Dzikrina Putri Kennedy Artahsasta Gonbei Khairunnisa, Dhia Fairuz Kharisma, Made Deva Khoirunnisa' Mufiidatun Ummah ZA Lipinwati ., Lipinwati Lisa Susanti Mahendra, Mhd Habib Dwi Makmur, M. Jufri Maria Estela Karolina Maria, Ima Mayani, Gita Miftahurrahmah Miftahurrahmah, Miftahurrahmah Moniga, Agra Farellio Muhammad Anggamguna Mulyadi, Deri Mursalin, Adhywira Nabila Putri, Zahra Nur, Amrizal Muhammad NURIYAH Nuriyah Nuriyah Nuriyah Nuriyah Nuriyah Nuriyah Nuriyah, Nuriyah Nurul Izza Nyimas Natasha Ayu Shafira Octaviani, Jelica Oxalis, Siti Chalista Zaisha Putri Sari Wulandari Putri, Nadhilah Rahmadani, Firinia Raihanah Suzan Ramadhan, Ghozi F. Ratna Sugiati Riasari, Vonna Rina Nofri Enis Rina Nofrienis Rita Halim rizkiyani noor, amadea Rohman, Umi Rofiqul Jannah Shabrina Nadilah Zahra Subhan, Rahmatika Sugianti, Ratna Sugiarti, Ratna Sugiati, Ratna Susanti, Febriyolla Suzan, Raihanah Tarawifa, Susan Tia Wida Ekaputri Viapita, Brilianti Wahyu Indah Dewi Aurora Wahyuningtias, Isna Rizkia William Gading, Patrick Zami, Muh. Husni Zam Zamzami , Mhd Usni Zul Andriatha