p-Index From 2021 - 2026
5.684
P-Index
Claim Missing Document
Check
Articles

Natural Deep Eutectic Solvent–Extracted Old and Young Mangrove Avicennia marina Leaves: Comparative Antibacterial Activity Against Propionibacterium acnes Djamaludin, Heder; Firdaus, Shelina Innasa; Suprayitno, Eddy; Yahya, Yahya; Arisandi, Desy; Ahmad, Mirza Gulam; Tambunan, Jeny Ernawati; Ahmad, Nurul Hawa; Ramli, Nurul Shazini; Kartikaningsih, Hartati
Journal of Tropical Life Science Vol. 15 No. 3
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.15.03.13

Abstract

Acne vulgaris is a common inflammatory skin disorder largely associated with the proliferation of Propionibacterium acnes. Although antibiotics are widely used for acne treatment, the increasing incidence of antibiotic resistance necessitates the exploration of effective natural alternatives. Mangrove plants are known to contain diverse bioactive compounds with antimicrobial potential. This study aimed to evaluate the antibacterial activity of Natural Deep Eutectic Solvent (NADES) extracts derived from young and old leaves of Avicennia marina against P. acnes. Extraction was conducted using citric acid–glucose-based NADES with different molar ratios: P1 (1:1), P2 (2:1), P3 (3:1), and P4 (4:1), to assess the effect of solvent composition on antibacterial performance. Antibacterial activity was determined using inhibition zone assays, while molecular docking analysis was performed to investigate interactions between extracted metabolites and P. acnes target proteins. The results showed that both young and old leaf extracts exhibited significant antibacterial activity, strongly influenced by the NADES formulation. Young leaf extracts produced the largest inhibition zone with the P4 formulation (24.51±0.75 mm) and the smallest with P1 (21.63±0.67 mm). Similarly, old leaf extracts showed maximum inhibition in P4 (37.38±4.34 mm) and minimum inhibition in P1 (22.62±1.40 mm). Increasing the proportion of citric acid enhanced the extraction of bioactive compounds responsible for antibacterial activity. Molecular docking confirmed strong binding affinities between key metabolites and P. acnes target proteins, supporting the experimental findings. Thus, NADES extracts of A. marina leaves, particularly those prepared using a 4:1 citric acid–glucose ratio, demonstrate strong potential as natural antibacterial agents for acne prevention and treatment.
Effects of Shrimp Aquaculture Effluent on the Habitat Suitability for Macrozoobenthos along the Situbondo Coast Salimatul Muntafi’ah; Hartati Kartikaningsih; Fitri Candra Wardana; Wresti L. Anggayasti
Jurnal Penelitian Pendidikan IPA Vol 12 No 2 (2026)
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v12i2.13571

Abstract

Shrimp aquaculture generates wastewater that may affect coastal ecosystem quality if not properly managed. This study aimed to analyze the relationship between shrimp pond effluent quality and macrozoobenthos diversity as an indicator of habitat suitability in the coastal waters of Situbondo, Indonesia. Wastewater samples were collected from pond outlet wastewater treatment plants (WWTP) in triplicate and analyzed for physicochemical parameters, including phosphate (PO₄), ammonia (NH₃), total suspended solids (TSS), biochemical oxygen demand (BOD), and pH. Macrozoobenthos samples were collected at three distances from the discharge point and analyzed using the Shannon–Wiener diversity index (H'). Data were further analyzed using multiple linear regression and Canonical Correspondence Analysis (CCA) to evaluate the relationship between environmental variables and macrozoobenthos diversity. The results showed that PO₄ concentrations at all stations exceeded the environmental quality standard (0.5 mg/L), while NH₃ concentrations exceeded the standard (5 mg/L) at four stations. TSS levels also exceeded the permitted threshold (100 mg/L) at several stations, whereas BOD and pH remained within acceptable limits. The macrozoobenthos diversity index indicated moderate diversity at stations 1 and 2 (H' ≈ 2), suggesting moderate environmental stress, while stations 3, 4, and 5 showed low diversity (H' < 1), indicating polluted conditions. Regression analysis indicated that nutrient and suspended solid parameters negatively influenced macrozoobenthos diversity, with PO₄ and NH₃ showing the strongest effects. The findings demonstrate that shrimp pond effluent can alter benthic community structure and confirm that macrozoobenthos are effective bioindicators for assessing ecological impacts in coastal ecosystems.
Integration of Spatial and Social Analysis for Safe Sanitation in Cemorokandang Urban Village to Support the Achievement of Sustainable Development Goal 6.2.1 Nike Poerbyanti; Hartati Kartikaningsih; Mufidah Afiyanti
Jurnal Penelitian Pendidikan IPA Vol 12 No 2 (2026)
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v12i2.13666

Abstract

Safe sanitation is crucial for protecting public health and the environment, particularly in densely populated urban areas where inadequate facilities heighten contamination risks. Cemorokandang Urban Village represents such a vulnerable area, requiring a comprehensive assessment to inform local sanitation planning. This study evaluates the condition of safe sanitation and identifies spatial and social factors influencing its achievement using a mixed-method approach that integrates surveys, field observations, water quality testing, and GIS-based spatial analysis. Primary data covered household sanitation facilities, open defecation practices, and water quality, while secondary data were obtained from local institutions. Findings indicate that although all households have toilets with domestic wastewater systems, only 3,25% (211 of 6.497 buildings) met safely managed sanitation criteria despite 96.75% having adequate facilities. Spatial analysis reveals significant variation in sanitation risk across neighborhoods, strongly linked to differences in education, income, and community behavior. Communities with stronger socio-economic capacity demonstrate better understanding and adoption of safe sanitation practices, supported by training and balanced gender participation. Integrating spatial and social data provides a detailed picture of local challenges and supports the design of community-based, location-specific, and gender-responsive interventions. The study recommends targeted actions in high-risk areas, strengthened behavioral training, and inclusive financing mechanisms to accelerate progress toward Sustainable Development Goal 6.2.1.
Embung Bandung Bondowoso Tourism Sustainability Strategy in Sidobandung Village, Balen District, Bojonegoro Regency Amilis Setyandhinavia; Hartati Kartikaningsih; Setyo Tri Wahyudi
Jurnal Penelitian Pendidikan IPA Vol 11 No 2 (2025): February
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i2.6726

Abstract

Embung Bandung Bondowoso Tourism offers water tourism which originates from the Pacal River, Bojonegoro Regency. The choice for developing Embung Bandung Bondowoso tourism is because it is to utilize the embung which has been owned since 2020. Even though Bandung Bondowoso tourism has been open since February 1st 2022 and is currently still in the development process. The development of tourist villages is also a form of accelerating integrated village development to encourage social, cultural and economic transformation of villages. This research uses quantitative research methods. In this research, this was done by filling out a Multidimensional Scaling questionnaire and then analyzing the quantitative data obtained to answer the problem formulation regarding the sustainability status of the research location. The resulting index value shows that the 5 dimensions (ecological, social, economic, institutional and technological) of Embung Bandung Bondowoso Tourism already have very good sustainability status. The sensitive attributes that most influence sustainability and need to be considered are green open spaces, condition and availability of clean water, landslides, erosion and damage to water resources, conflicts of interest between residents, level of education, development of local products, community service providers and ease of reaching the location.
The Correlation between Environmental Sanitation and Stunting Management through Women's Interventions and Food Security in Pre-School Age Children Rizdya Oktofani; Hartati Kartikaningsih; Nurul Badriyah
Jurnal Penelitian Pendidikan IPA Vol 11 No 1 (2025): January
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i1.8265

Abstract

Stunting is a chronic nutritional deficiency that impedes growth and affects the development of body and brain cells. Addressing stunting requires multisectoral collaboration to reduce and prevent stunting among children under 5 years old, the critical "Golden Age" period. Malang City's stunting rate was 18% in 2022, 16% in 2023, with a 2024 target of 14%. Achieving zero stunting involves a multidisciplinary approach, considering environmental, social, and economic factors within a sustainable development framework. This study examines the roles of the community, stakeholders, and government in stunting management. A quantitative approach using explanatory research was conducted on pre-school children in Karangbesuki Village, with a sample of 112 families at risk of stunting from a population of 584. Data was collected through offline questionnaires, and analysis was performed using SEM-PLS software. The study found that environmental sanitation had no significant direct effect on stunting management but positively influenced women's intervention and food security. Both women's intervention and food security significantly impacted stunting management. Furthermore, women's intervention and food security played a perfect mediating role in the relationship between environmental sanitation and stunting management. Future research should consider expanding the sample size and exploring additional independent variables beyond the current framework.
Pengaruh Ekstraksi Hijau Menggunakan NADES Terhadap Karakteristik Ekstrak Daun Tua Mangrove Avicennia marina Desy Arisandi; Hartati Kartikaningsih; Heder Djamaludin; Febrian Salim Prasetyo; Mirza Gulam Ahmad; Jeny Ernawati Tambunan; Gilang Rusrita Aida; Kristina Marsela
Juvenil Vol 7, No 2: Mei (2026)
Publisher : Department of Marine and Fisheries, Trunojoyo University of Madura, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21107/juvenil.v7i2.33201

Abstract

Ekstraksi hijau menggunakan Natural Deep Eutectic Solvent (NADES) berpotensi meningkatkan efisiensi perolehan senyawa bioaktif dari bahan mangrove. Penelitian ini bertujuan menganalisis pengaruh variasi rasio mol NADES asam sitrat:glukosa terhadap karakteristik ekstrak daun tua mangrove Avicennia marina, meliputi kadar air simplisia, rendemen, pH, dan profil fitokimia kualitatif. Penelitian menggunakan Rancangan Acak Lengkap nonfaktorial dengan empat perlakuan rasio mol (1:1, 2:1, 3:1, 4:1) dan empat ulangan. Simplisia dibuat dari daun tua, kemudian diekstraksi menggunakan NADES, diikuti pengukuran rendemen dan pH serta skrining fitokimia (alkaloid, flavonoid, saponin, tanin, steroid, terpenoid). Data rendemen dan pH dianalisis menggunakan ANOVA dan uji Tukey (α=5%). Kadar air simplisia sebesar 8,40±0,53%. Rendemen meningkat seiring kenaikan rasio asam sitrat dengan nilai tertinggi pada 4:1 (76,90±0,47%) dan terendah pada 1:1 (74,60±1,10%). pH ekstrak menurun dari 1,88±0,02 (1:1) menjadi 1,51±0,02 (4:1). Skrining fitokimia menunjukkan flavonoid, tanin, dan alkaloid terdeteksi pada semua perlakuan. Rasio 4:1 direkomendasikan sebagai kondisi awal untuk standardisasi ekstrak dan penelitian lanjutan berbasis kuantifikasi dan bioaktivitas.
Assessing Tropical River Water Quality and Pollution Drivers Using CCME-WQI and PCA Apsari, Selfi'un Linda; Kartikaningsih, Hartati; Pertiwi, Maharani
Civil and Environmental Science Journal (CIVENSE) Vol. 9 No. 1 (2026)
Publisher : Fakultas Teknik Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

City rivers in rapidly expanding tropical regions face considerable degradation due to domestic wastewater and urban runoff. Our study uses the Canadian Council of Ministers of the Environment Water Quality Index (CCME WQI) and Principal Component Analysis (PCA) to assess water quality in the Gembong River, Pasuruan City. It introduces a new integrative approach by combining the CCME-WQI and PCA to simultaneously assess overall water quality status and identify key pollution-causing parameters along with their seasonal variability, addressing the limitations of previous studies that applied these methods separately without linking pollution sources to temporal dynamics. Sampling was conducted at five stations during the rainy, transitional, and dry seasons. Results showed that all stations fell into the Poor category (WQI 37.71–45.67), with Station 2 exhibiting the lowest quality due to dense settlements and untreated drainage discharge. Seasonal analysis revealed significant variations in fecal coliforms, which peaked during the rainy season due to runoff. PCA identified BOD, COD, and fecal coliform as dominant domestic‑wastewater indicators, while TSS and phosphate reflected land‑use effects. A weak negative correlation between rainfall and BOD–COD suggests continuous wastewater input is the primary driver of pollution. These findings imply that pollution control strategies should prioritize the reduction of BOD, COD, and fecal coliform through improved domestic wastewater treatment systems, particularly in densely populated areas, while TSS and phosphate management should focus on controlling surface runoff and land use practices. These results provide a scientific basis for targeted pollution control and adaptive urban water management strategies to support sustainable river governance.
Assessment of coliform bacteria contamination in the Brantas River as a bioindicator of sanitation and clean water source quality Wardah, Nihaya Nailatul; Kartikaningsih, Hartati; Koentjoro, Maharani Pertiwi
Jurnal Pembangunan dan Alam Lestari Vol. 17 No. 2 (2026): Jurnal Pembangunan dan Alam Lestari
Publisher : Graduate School of Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jpal.2026.017.02.07

Abstract

River monitoring for bacterial contamination plays a vital role in preventing waterborne disease transmission and safeguarding public health, particularly in densely populated areas with inadequate sanitation infrastructure. Human activities such as domestic wastewater discharge, improper waste disposal, and agricultural runoff significantly influence microbial communities in aquatic ecosystems and may increase the spread of pathogenic microorganisms and antibiotic resistance. Escherichia coli (E. coli) is widely recognized as a reliable indicator of fecal contamination and overall water quality because its presence suggests potential contamination by enteric pathogens that pose risks to human health. This study aimed to assess coliform bacteria levels in river water as bioindicators of sanitation conditions and the quality of clean water sources. A descriptive-quantitative research design was employed to obtain measurable and systematic data. Water samples were collected from three river locations situated in areas characterized by poor sanitation systems. The selected sites represent zones where domestic activities directly interact with river water, potentially contributing to microbial pollution. Coliform bacteria concentrations were analyzed using the Most Probable Number (MPN) method to estimate bacterial density in each sample. The results demonstrated that coliform contamination levels varied across sampling points and reflected surrounding sanitation conditions. Elevated coliform counts indicated significant fecal pollution, confirming that coliform bacteria are effective bioindicators for evaluating sanitation performance and clean water source quality in riverine environments.
Drainage System Optimization as an Effective Flood Management Strategy in Urban Regions: A Systematic Review Utilizing PRISMA Indah Ashlachal Ummah; Hartati Kartikaningsih; Mulabbi Andrew
Sustainability: Theory, Practice and Policy Vol. 5 No. 2 (2025): Sustainability: Theory, Practice and Policy December Edition
Publisher : Pusat Kajian Berkelanjutan UIN Sulthan Thaha Saifuddin Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30631/sdgs.52.3771

Abstract

Flood disasters cause significant damage and losses in various cities around the world. One of the contributing factors is poor drainage system management. This literature review study aims to explore the effectiveness of drainage systems in addressing flood problems in major cities across the globe. The study utilizes a systematic literature review design with the PRISMA method. Data is sourced from the Scopus database. The document analysis process involves several stages: identification, screening, eligibility, and inclusion, ultimately resulting in 25 articles that align with the objectives of this study. The results indicate that there are three aspects to optimizing drainage systems as an effective flood management strategy in major cities: 1) Smart Technology-Based Drainage System Management, 2) Policy and Regulation-Based Drainage Management, 3) Community and Social Adaptation-Based Drainage Management, and 4) Geomorphology and Natural Process-Based Drainage Management. This literature review is expected to provide practical recommendations for improving drainage systems to be more adaptive and sustainable in addressing increasingly complex flood challenges in the future, particularly in Indonesia.
Co-Authors A'yunin, Qurrota A'yunin, Qurrota Abdul Aziz Jaziri Abdul Mulki Purnama Afifa, Faisa Agung Pramana Warih Marhendra Agung Pramana Warih Marhendra, Agung Pramana Warih Agus Susilo Agus Susilo Ahmad, Mirza Gulam Ahmad, Nurul Hawa Al Fatih, Ahmad Nuril Fuad Alif, Muhammad Rizki Mas Alifatul Fatchiyah Alviani, Melinda Nuril Amilis Setyandhinavia Andi Kurniawan Anggraeni, Ike Listya Anies Chamidah Anik M. Hariati Anshary, Muhammad Reza Apsari, Selfi'un Linda Arifin, Nasrullah Bai Arifin, Sunanto Arning Wilujeng Ekawati Asep Awaludin Prihanto Ashari, Fadhil Muhamad Atikawati, Dini Audina, Nanda Bagyo Yanuwiadi Bambang Semedi Budi Wahono Citra Satrya Utama Dewi Darius Darius Defri Yona Desy Arisandi Dewa Gede Raka Wiadnya Dian Wahyu Wardani Dini Atikawati Djamaludin, Heder Eddy Suprayitno Fauziyah, Jihan Nur Febrian Salim Prasetyo Feni Iranawati Feni Iranawati, Feni Firdaus, Shelina Innasa Fitri Candra Wardana Fuad, Mochamad Arif Zainul Galih Nugroho Gilang Rusrita Aida Gunawan, Fahdynia Karnira Habibah, Laila Nur Happy Nursyam Hardoko Hardoko Heder Djamaludin Ike Listya Anggraeni Indah Ashlachal Ummah Jeny Ernawati Tambunan K, Maharani Pertiwi Kasitowati, Rarasrumdyah Ken Audia Pradarameswari Khotibul Umam Al Awwaly Khusaini, Mohammad Kristama, Yoga Sita Kristin Rosalina Kristina Marsela Kuncoroyekti, Andre Ledhyane Ika Harlyan Lestariadi, Riski Agung Lina Asmara Wati Lina Asmarawat Luchman Hakim M. Choirul Anam Madyasta Anggana Rarassari Maharani Pertiwi Koentjoro Maharani, Sarastria Mimit - Primyastanto Mirna Zena Tuarita Mirza Gulam Ahmad Mochamad Arif Zainul Fuad Mufidah Afiyanti Mufti, Eka Deviana Muhamad Firdaus Muhamad Khafid Rifai Muhammad Rizki Mas Alif Mulabbi Andrew Nasrullah Bai Arifin Nike Poerbyanti Nurhanif, Ardhian Eko Nurul Badriyah Nurul Catur Febriana Oktavia, Yoan Pertiwi, Maharani Putra, Erwansyah Ilham Pradana Qomariyatus Sholihah Rachman Hartono Ramli, Nurul Shazini Rhytia Ayu Christianty Putri Rifai, Muhamad Khafid Rika Kurniaty Rizdya Oktofani Rizki Fadila, Rizki Roosa, Lucy Cynthia Salimatul Muntafi’ah Saputra, Nyoman Robby Manik Sari, Safitri Permata Sartika, Fitarina Setyo Tri Wahyudi Soemarno Soemarno Sri Andayani Sri Andayani Sri Sudaryanti, Sri Subagyo Subagyo Sukoso Sukoso Supirman, S S Supriyadi Supriyadi Surjono Susanto, Dony Tri Syarifah Hikmah Julinda Sari Tambunan, Jenny Ernawati Tambunan, Jeny Ernawati Tian Nur Ma’rifat Toat, Akhmad Prasetyo Ibnu Wahyu Devi Hapsari Wijayanti Wardah, Nihaya Nailatul Wiadnya D.G R Wresti L. Anggayasti Yahya Yahya Yanti Suryanti Yanuar, Adi Tiya YOGA DWI JATMIKO Yunita Eka Puspitasari Zaelanie, K Kartini Zaelanie, K Kartinie