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All Journal Journal of Biomedicine and Translational Research Molecular and Cellular Biomedical Sciences (MCBS) Syntax Literate: Jurnal Ilmiah Indonesia SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Muara Sains, Teknologi, Kedokteran dan Ilmu Kesehatan Syntax Idea Jurnal Bakti Masyarakat Indonesia Jurnal Scientia MAHESA : Malahayati Health Student Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research Tarumanagara Medical Journal Jurnal Pengabdian Masyarakat Nusantara Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara Termometer: Jurnal Ilmiah Ilmu Kesehatan Dan Kedokteran Jurnal Keperawatan Bunda Delima Jurnal Pengabdian Kolaborasi dan Inovasi IPTEKS Jurnal Kabar Masyarakat Jurnal Abdimas Indonesia Ebers Papyrus Jurnal Muara Medika dan Psikologi Klinis Journal of Community Service and Society Empowerment Karunia: Jurnal Hasil Pengabdian Masyarakat Indonesia Jurnal Pengabdian Sosial Jurnal Serina Abdimas
Sidarta, Erick
Departemen Biologi Universitas Tarumanagara, Indonesia
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Skrining Kesehatan Kulit dengan Penilaian Kadar Air dan Minyak pada Kelompok Usia Produktif di Sekolah Kalam Kudus II, Duri Kosambi Sidarta, Erick; Averina, Friliesa; Herdiman, Alicia; Destra, Edwin
Jurnal Kabar Masyarakat Vol. 2 No. 3 (2024): Agustus : JURNAL KABAR MASYARAKAT
Publisher : Institut Teknologi dan Bisnis Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54066/jkb.v2i3.2226

Abstract

Skin health, as the body's largest organ, is an important aspect of health. It plays an important role such as: protection against pathogens, regulating temperature, and preventing fluid loss. Internal factors such as genetics, hormones, and general health, as well as external factors such as UV exposure, pollution, skin care habits, and diet, influence skin health. The aim of this activity is to increase health awareness and provide education about the importance of maintaining healthy skin. Community service activities were done at Kalam Kudus II High School using the PDCA (Plan-Do-Check-Act) method. At the planning stage, skin health problems were identified and educational activity plans were drawn up. Implementation includes health seminars, individual consultation sessions, and skin examinations using a skin analyzer to assess the oil and water content of the skin. Evaluation was carried out by collecting feedback from participants, and follow-up actions were prepared based on the evaluation results. A total of 68 participants took part in this activity. It was observed that in 18-35 year age group, skin conditions were more stable compared to the 36-50 year age group. In which the latter was starting to show signs of skin aging. This also shown in the 51-64 year age group whom experiencing dry skin and other skin problems more often.
Kegiatan Penapisan Kadar Air dan Minyak Kulit Sebagai Deteksi Dini Kulit Kering di SMAN 75, Jakarta Utara Sidarta, Erick; Gunaidi, Farell Christian; Destra, Edwin; Fadhila, Arni Ismi
jurnal ABDIMAS Indonesia Vol. 2 No. 2 (2024): Juni : Jurnal ABDIMAS Indonesia
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jurai.v2i2.1607

Abstract

Skin hydration is critical to maintaining healthy skin, as the skin functions as a physical barrier against external environmental factors such as pathogen invasion, UV radiation, chemical exposure, and mechanical trauma. This activity highlights the importance of early detection of skin hydration levels to prevent conditions such as dry skin with a Plan-Do-Check-Action (PDCA) approach. Effective strategies such as regular use of moisturizer, a healthy diet, increased fluid intake, a gentle skin cleansing routine, and regular monitoring using a skin analyzer are important to maintain healthy skin. Community education and screening demonstrated a positive impact on skin hydration awareness and practice, emphasizing the importance of hydration in improving skin barrier function and overall quality of life.
Demensia : Patofisiologi, Faktor Resiko dan Peran Inflamasi dalam Perkembangan Penyakit Erick Sidarta; Triyana Sari; Sari Mariyati Dewi Nataprawira
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 3 No. 1 (2025): Januari : Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v3i1.4801

Abstract

Dementia is a complex neurodegenerative syndrome characterized by cognitive decline, including memory impairment, difficulty in thinking, and social interaction, which can affect daily activities. This condition is often caused by other diseases, including Alzheimer’s disease, vascular dementia, Lewy body dementia, and frontotemporal dementia, each with unique pathological mechanisms. Alzheimer’s disease, the leading cause of dementia, involves the accumulation of beta-amyloid plaques and tau tangles that disrupt neuronal function and trigger chronic inflammation. Vascular dementia results from impaired blood flow to the brain, while Lewy body dementia is associated with the misfolding of alpha-synuclein protein. Meanwhile, frontotemporal dementia is linked to the accumulation of tau or TDP-43 proteins, causing degeneration of the frontal and temporal lobes. Aging is the primary risk factor for dementia through the process of inflammaging, a low-grade chronic inflammation caused by persistent activation of the immune system. Inflammaging accelerates neurodegeneration by increasing oxidative stress, mitochondrial dysfunction, and the accumulation of pathological proteins. Additionally, neuroinflammation plays a crucial role by over activating microglia, which exacerbates neuronal damage. The combination of inflammation as both a trigger and a consequence create a pathological cycle that accelerates the progression of dementia. Preventive strategies include managing modifiable risk factors such as hypertension, diabetes, obesity, and adopting a healthy lifestyle, alongside developing therapies targeting inflammaging and neuroinflammation. A deeper understanding of these pathophysiological and inflammatory mechanisms is essential to support the development of multidisciplinary interventions to reduce the global burden of dementia.
Pelatihan Bantuan Hidup Dasar Petugas Tata Kelola dan Pemuda Gereja Paroki Santo Fransiskus Asisi Tebet Sidarta, Erick; Dwiana, Alya; Sukianto, Louise Audrey; Kasvana, Kasvana; Tan, Nikita
Karunia: Jurnal Hasil Pengabdian Masyarakat Indonesia Vol. 4 No. 1 (2025): Jurnal Hasil Pengabdian Masyarakat Indonesia
Publisher : Fakultas Teknik Universitas Maritim AMNI Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58192/karunia.v4i1.3085

Abstract

Sudden cardiac arrest is a condition that occurs quite frequently. This sudden cessation of heart function is caused by the loss of electrical activity in the heart, which results in the cessation of blood circulation throughout the body. Quick and proper handling of this condition can reduce the mortality rate due to cardiac arrest. Therefore, Basic Life Support (BLS) training needs to be conducted to educate the general public. The BLS training conducted for the management officers and youth of Saint Francis of Assisi Church in Tebet was carried out by providing theoretical and practical BLS lessons, as well as conducting pre-tests and post-tests to assess the participants' understanding of the material and practices provided. From the activity conducted, a total of 22 participants attended the BLS training, and there was a significant difference in the average pre-test and post-test scores. It can be concluded that the training provided was effective in increasing the participants' understanding and knowledge of BLS.
Relationship between MC4R rs17782313 Polymorphism and Body Mass Index and Appetite Regulation in Young Adults in Indonesia Sidarta, Erick; Kumala, Meilani
Journal of Biomedicine and Translational Research Vol 11, No 1 (2025): April 2025
Publisher : Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jbtr.v11i1.26018

Abstract

Background: Obesity is an increasing public health problem, including among young adults in Indonesia. Genetic, environmental, and behavioral factors contribute to obesity. One of the genetic variants associated with obesity is the MC4R rs17782313 polymorphism, which plays a role in appetite regulation and energy balance.Objective: This study aims to determine the relationship between the MC4R rs17782313 polymorphism and Body Mass Index (BMI) in young adults in Indonesia and to evaluate its effect on feelings of hunger, satiety and eating satisfaction.Method: We conducted a cross-sectional study involving 152 young adults at Universitas Tarumanagara. Genotyping was done using the real-time PCR method with the KASP™ system. To evaluate hunger, satiety, and eating satisfaction, we used the Visual Analog Scale (VAS; 0–100 mm, where lower scores indicate intense sensations of hunger, satiety, and satisfaction) before and after meals and calculated the difference scores. We analyzed the data using R software.Results: The results showed no significant relationship between the MC4R rs17782313 polymorphism and BMI (p = 0.7). However, there was a significant difference in hunger scores between the TT and TC genotypes (p = 0.024), where individuals with the TT genotype experienced a greater reduction in hunger after eating than individuals with the TC genotype. In addition, we also found a significant difference in BMI based on gender in our young adult population (p = 0.0032).Conclusion: This study found that MC4R rs17782313 was not significantly associated with BMI in this population. However, the variant may influence appetite regulation, as individuals with the TT genotype showed a smaller reduction in hunger after eating. A significant BMI difference between sexes was also observed; these findings suggest a role for MC4R in eating behavior, warranting further investigation in larger, diverse populations.
Peran Edukasi dan Evaluasi Handgrip Strength sebagai Upaya Deteksi Dini Sarcopenia pada Usia Produktif di Cengkareng Sidarta, Erick; Santoso, Alexander Halim; Destra, Edwin; Wijaya, Bryan Anna; Setiawan, Fiona Valencia
Journal of Community Service and Society Empowerment Том 3 № 02 (2025): Journal of Community Service and Society Empowerment
Publisher : PT. Riset Press International

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59653/jcsse.v3i02.1777

Abstract

Hydrated skin is an important indicator of overall skin health, as water content in the stratum corneum plays a vital role in maintaining the skin barrier function. Insufficient hydration can lead to dry skin, increase the risk of infections, and reduce quality of life. This activity aimed to assess skin water and oil levels among the elderly residents at Hana Nursing Home to prevent dry skin conditions. The PDCA (Plan–Do–Check–Act) approach was applied, which included planning the screening activities, measuring skin water and oil levels, evaluating the results, and providing skin care education for participants with abnormal findings. A total of 36 elderly individuals participated in this activity at Hana Nursing Home, South Tangerang. The results showed that 20 participants (55.56%) had low oil levels, while 24 participants (66.67%) had low water levels. These findings underscore the importance of maintaining skin hydration through adequate fluid intake, regular use of moisturizers, and adopting a healthy lifestyle. Early detection of skin hydration status, combined with targeted education, is effective in preventing dry skin and improving quality of life in the elderly population.
EDUKASI EFEK KONSUMSI NATRIUM TERHADAP TEKANAN DARAH DAN SKRINING UNTUK DETEKSI DINI RISIKO HIPERTENSI PADA USIA PRODUKTIF Sidarta, Erick; Santoso, Alexander Halim; Destra, Edwin; Edbert, Juan; Alexandro, Cristian
Jurnal Pengabdian Kolaborasi dan Inovasi IPTEKS Vol. 3 No. 3 (2025): Juni
Publisher : CV. Alina

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59407/jpki2.v3i3.2609

Abstract

Tekanan darah tinggi pada usia produktif dapat berkembang tanpa gejala dan sering tidak terdeteksi tanpa pemeriksaan langsung. Kegiatan ini bertujuan untuk melakukan skrining tekanan darah dan memberikan edukasi mengenai peran konsumsi natrium terhadap peningkatan tekanan darah. Pemeriksaan dilakukan menggunakan tensimeter digital otomatis dan diklasifikasikan ke dalam tiga kategori: tekanan darah normal, pre-hipertensi, dan hipertensi. Hasil skrining menunjukkan bahwa 53,06% peserta termasuk kategori hipertensi, 30,61% pre-hipertensi, dan hanya 16,33% memiliki tekanan darah normal. Edukasi disampaikan secara kolektif menggunakan media poster yang menekankan pembatasan natrium harian serta identifikasi makanan dengan kandungan garam tinggi. Kegiatan ini disusun sebagai bagian dari upaya promotif dan preventif untuk meningkatkan kesadaran terhadap hipertensi dan gaya hidup yang berkontribusi terhadap pengendalian tekanan darah. Kata Kunci: Hipertensi, Tekanan Darah, Natrium, Usia Produktif, Edukasi Gizi, Strategi Preventif
DEVELOPMENT OF AMPLIFICATION REFRACTORY MUTATION SYSTEM PCR TO DETECT ANDROGEN RECEPTOR GENE G1773A (RS6152) POLYMORPHISM Triyana Sari; Erick Sidarta; Sari Mariyati Dewi Nataprawira; Giovani Evangelista Alfonsius; Damar Sajiwo
Jurnal Scientia Vol. 12 No. 03 (2023): Education, Sosial science and Planning technique, 2023 (June-August)
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Androgen receptor (AR) is a ubiquitous receptor responsible for responses by androgen stimulus. Androgen, a hormone which will bind to the AR, is essentials for normal male sexual development. Nevertheless, one of the polymorphisms in the AR gene, G1733A (rs6152) have been associated with numerous clinical risks such as cardiovascular disease (CD), androgenetic alopecia, high prostate-specific antigen (PSA) levels, male infertility, recurrent spontaneous abortions and prostate cancer. This study aims to develop an alternative and cost-effective method to detect G1773A (rs6152) polymorphism. In this study, amplification refractory mutation system-polymerase chain reaction (ARMS-PCR) using two pair of primers was used to detect the G1733A (rs6152) polymorphism. Primer design was done using http://primer1.soton.ac.uk/primer1.html online tools and then manually adjusted to increase the specificity. A total of 54 samples were screened using ARMS PCR and 2 representative samples of each allele from previous screening were used to validate the results using Sanger DNA sequencing. Among 54 subjects screened, we found 52 (96.3%) subjects carry G allele and 2 (3.7%) subjects carry A allele. No heterozygote was found in this study. The frequency of G allele was 96.97% and the frequency of A allele was 3.03%. Result validation using DNA sequencing was in agreement with ARMS-PCR method results. ARMS-PCR can be used as efficient alternative for genotyping of G1733A (rs6152) AR gene polymorphism
Evaluasi Lemak Subkutan melalui Skinfold Caliper Empat Titik sebagai Media Edukasi Komposisi Tubuh untuk Pencegahan Obesitas Sidarta, Erick; Santoso, Alexander Halim; Destra, Edwin; Riadi, Seravin Janet; Sartono, Stefanny
Jurnal Pengabdian Sosial Vol. 2 No. 9 (2025): Juli
Publisher : PT. Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/vw3hj092

Abstract

Lemak subkutan merupakan jaringan penyimpanan energi utama yang dapat mengalami akumulasi akibat asupan kalori berlebih. Pemeriksaan lipatan kulit menggunakan skinfold caliper menjadi metode skrining non-invasif yang efektif untuk mendeteksi peningkatan lemak subkutan sebelum munculnya manifestasi obesitas klinis. Kegiatan dilaksanakan di Gereja St. Fransiskus Asisi, Jakarta Selatan, dengan melibatkan 65 peserta. Pemeriksaan dilakukan pada empat titik tubuh: biseps, trisep, suprailiaka, dan subsubsubskapula. Hasil digunakan untuk menyampaikan edukasi personal terkait gaya hidup dan risiko obesitas. Ketebalan tertinggi ditemukan pada titik suprailiaka (rerata 18,93 mm), diikuti oleh trisep (15,8 mm), subsubskapular (13,22 mm), dan biseps (10,51 mm). Edukasi disampaikan berdasarkan hasil masing-masing peserta untuk meningkatkan pemahaman terhadap pentingnya pengaturan kalori dan aktivitas fisik. Pemeriksaan skinfold caliper dapat digunakan sebagai skrining awal akumulasi lemak subkutan dan menjadi sarana efektif dalam edukasi promotif-preventif untuk mencegah obesitas berbasis komunitas.
Peran Kadar Gula Darah dan Asam Urat terhadap Komposisi Lemak dan Massa Otot Wanita Dewasa di Jakarta: Studi Multisenter dengan Kontrol Usia: The Role of Blood Sugar and Uric Acid Levels on Fat Composition and Muscle Mass in Adult Women in Jakarta: A Multicenter Study with Age Control Sari, Triyana; Santoso, Alexander Halim; Sidarta, Erick; Wijaya, Christian; Satyanegara, William Gilbert
Jurnal Keperawatan Bunda Delima Vol 7 No 2 (2025): EDISI AGUSTUS
Publisher : Akademi Keperawatan Bunda Delima Bandar Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59030/jkbd.v7i2.176

Abstract

Pendahuluan: Prevalensi diabetes melitus dan hiperurisemia yang meningkat pada wanita dewasa di Indonesia menjadi perhatian karena berkaitan dengan peningkatan lemak tubuh dan penurunan massa otot. Lemak viseral diketahui sebagai prediktor risiko metabolik, sementara massa otot penting dalam regulasi glukosa. Namun, studi untuk evaluasi hubungan antara kadar gula darah, asam urat, dan komposisi tubuh pada populasi wanita Indonesia masih terbatas. Metode: Penelitian ini merupakan studi potong lintang multisenter di enam kelurahan DKI Jakarta, melibatkan 325 perempuan dewasa yang dipilih secara purposive. Data dikumpulkan melalui pemeriksaan gula darah puasa dan asam urat dari darah vena setelah puasa ≥8 jam, serta pengukuran komposisi tubuh menggunakan OMRON HBF-375. Analisis statistik dilakukan menggunakan uji korelasi Pearson dan partial correlation dengan usia sebagai variabel kontrol. Hasil: Rerata usia responden adalah 48,7 tahun (SD 13,26). Kadar gula darah puasa berkorelasi positif signifikan dengan total lemak tubuh (r = 0.175, p = 0.002), lemak viseral (r = 0.156, p = 0.005), dan lemak subkutan (r = 0.136, p = 0.014); korelasi tetap signifikan setelah kontrol usia (p < 0.05). Kadar asam urat juga berkorelasi signifikan dengan lemak viseral (r = 0.235) dan subkutan (r = 0.210), p < 0.001. Tidak ditemukan korelasi signifikan antara kedua biomarker dengan massa otot (p > 0.05). Kesimpulan: Gula darah dan asam urat berkaitan dengan peningkatan lemak tubuh secara independen terhadap usia, sedangkan penurunan massa otot lebih dipengaruhi oleh proses penuaan.
Co-Authors Alexander Halim Santoso Alexandro, Cristian Alvian Rendy Santoso Andianto, Ivan Christian Arlends Chris Arlends Chris Averina, Friliesa Bachri, Fiqi Afrizal Bryan Anna Wijaya Bryan Anna Wijaya Damar Sajiwo Damar Sajiwo Daniel Yohanes Putra David Limanan Destra, Edwin Dwiana, Alya Edbert, Juan Edwin Destra Fadhila, Arni Ismi Fajarivaldi, Kresna Bambang Fiona Valencia Setiawan Fiona Valencia Setiawan Giovani Anggasta Giovani Evangelista Alfonsius Giovani Evangelista Alfonsius Gunaidi, Farell Christian Herdiman, Alicia Herliani, Adellia Sheny Johny Hartawan Sutrisno Junius Kurniawan Kasvana, Kasvana Meilani Kumala Nataprawira, Sari Mariyati Dewi Ria Buana Ria Buana, Ria Riadi, Seravin Janet Rizqy Lazuardy Hasan S, Donatila Mano Sajiwo, Damar Santoso, Alexander Halim Saputera, Monica Djaja Sari M. Dewi Nataprawira Sari Mariyati Dewi Nataprawira Sari Mariyati Dewi Nataprawira Sari Mariyati Dewi Nataprawira Sartono, Stefanny Satyanegara, William Gilbert Setiawan, Fiona Valencia Sukianto, Louise Audrey Susy Olivia Lontoh Sutrisno, Johny Hartawan Tan, Nikita Tjie Haming Setiadi Triyana Sari Valdo, Louis Wijaya, Bryan Anna Wijaya, Christian Winata, Raymond