Article Per Year (5 Year)
p-Index From 2021 - 2026
3.37
P-Index
This Author published in this journals
All Journal Jurnal Kesehatan Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) JOPS (Journal Of Pharmacy and Science) Media Kesehatan Politeknik Kesehatan Makassar Jurnal Mandala Pharmacon Indonesia Jurnal Promotif Preventif Jurnal Kesehatan Tambusai Jurnal Farmasi dan Sains Indonesia (JFSI) Jurnal Buana Farma Journal of Experimental and Clinical Pharmacy (JECP) Jurnal EduHealth Sasambo Journal of Pharmacy Journal of Language and Health Jurnal Farmasi Sains dan Praktis Journal of Health Sciences and Medical Development Natural: Jurnal Pelaksanaan Pengabdian Bergerak Bersama Masyarakat Indonesian Journal of Medical and Pharmaceutical Science Kunir: Jurnal Farmasi Indonesia (KJFI) Journal of Pharmascience
Farid, Nurfiddin
Univeritas Megarezky Makassar
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

Published : 24 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 24 Documents
Search

 1   2   3 
Formulasi Sediaan Gel Basis HPMC Ekstrak Etanol Daun Jarak Cina (Jatropha multifida) Sebagai Penembuhan Luka Sayat pada Tikus Putih (Rattus norvegicus) Farid, Nurfiddin; Kalsum, Ummu; Yustisi, Juaella; Wahyuli, Resky
Sasambo Journal of Pharmacy Vol. 1 No. 2 (2020): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (418.369 KB) | DOI: 10.29303/sjp.v1i2.25

Abstract

Saat ini banyak penelitian yang mengembangkan tanaman berkhasiat untuk pengobatan tradisional. Salah satu tanaman yang dapat digunakan sebagai obat tradisional adalah tanaman Jarak cina (Jatropha multifida L). Berdasarkan pengalaman empiris secara turun temurun banyak digunakan oleh masyarakat khususnya Jeneponto, Desa Bulusibatang untuk menyembuhkan luka baru. Di Desa Bulusibatang lebih dikenal dengan tanaman ampicillin (Daun Jarak cina). Pemanfaatan tanaman obat masih perlu terus digali dan dikembangkan berdasarkan penelitian dan pengkajian secara mendalam seiring dengan kemajuan teknologi. Oleh karena itu, peneliti ingin melanjutkan penelitian dengan membuat sediaan farmasi untuk mempermudah penggunaannya secara topikal yaitu sediaan Gel ekstrak etanol Daun Jarak cina (Jatropha multifida L) untuk mengobati luka sayat pada tikus putih (Rattus novergecus). Penelitian ini merupakan penelitian Eksperimental Laboratorium yaitu Uji Efektivitas sediaan Gel ekstrak daun Jarak cina (Jatropha  multifida L) terhadap penyembuhan luka sayat pada Tikus putih (Rattus norvegicus). Data hasil pengamatan dianalisis dengan menggunakan metode analisis statistic yaitu analysis of variance (ANOVA) untuk mengetahui rata-rata kelompok perlakuan dan kelompok kontrol. Berdasarkan hasil penelitian, kontrol positif Bioplacenton lebih efektif dibandingkan kontrol negatif. Dan konsentrasi sediaan gel Ekstrak daun Jarak cina (Jatropha multifida) pada konsetrasi 15% yg paling efektif dalam penyembuhan luka sayat dibandingkan dengan konsetrasi 5% dan 10%.
Pengaruh Konsentrasi Ekstrak Etanol Daun Labu Siam (Sechium edule (Jacq.) Swartz) dalam Sediaan Gel Antibakteri terhadap Aktivitas Staphylococcus aureus Muzayyidah Muzayyidah; Muhammad Yusuf; Nurfiddin Farid; Jangga Jangga; Wira Anugrah
Journal of Pharmascience Vol. 10 No. 2 (2023): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v10i2.15341

Abstract

Daun labu siam (Sechium edule (Jacq.) Swartz) telah diidentifikasi mengandung flavonoid, tannin, dan saponin yang berpotensi sebagai antibakteri. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri formula sediaan gel ekstrak etanol daun labu siam dan pengaruh variasi konsentrasi ekstrak terhadap aktivitas tersebut pada Staphylococcus aureus. Formulasi sediaan gel ekstrak etanol daun labu siam dibuat dengan variasi konsentrasi ekstrak 10% (F1), 15% (F2), dan 20% (F3) dengan kontrol positif sediaan gel Klindamisin. Pengujian aktivitas antibakteri terhadap Staphylococcus aureus menggunakan metode sumuran dan pengamatan dilakukan dengan mengukur diameter zona hambat. Hasil pengujian menunjukkan F1 memiliki rata-rata diameter zona hambat sebesar 13,2 mm, F2 memiliki diameter zona hambat 15,4 mm, dan F3 memiliki diameter zona hambat 18,6 mm. Analisis data dengan uji One Way ANOVA menunjukkan adanya peningkatan diameter zona hambat yang signifikan setiap penambahan konsentrasi ekstrak daun labu siam dalam sediaan gel (p<0.05). Kata Kunci: Labu Siam, Gel Antibakteri, Metode Sumuran, Staphylococcus aureus, Zona Hambat Siamase Pumpkin Leaves (Sechium edule (Jacq.) Swartz) have been identified as containing flavonoids, tannins, and saponin potential as antibacterial agents. This study aims to determine the antibacterial activity of the etanol extract gel formulation of siamase pumpkin leaves and the effect of varying concentrations of the extract in Staphylococcus aureus activity. The formulation of siamase pumpkin leaves ethanol extract gel prepared using various extract concentration of 10% (F1), 15% (F2), and 20% (F3) with a positive control of clindamycin gel. Antibacterial activity against Staphylococcus aureus was tested using the well method and observations by measuring the inhibition zone. The results showed that F1 had an average inhibition zone of 13,2 mm, F2 had an inhibition zone of 15,4 mm, and F3 had an inhibition zone of 18,6 mm. Data analysis using the Oneway ANOVA test showed that there was an effect of the concentration of the ethanol extract of siamase pumpkin leaves in the gel preparation on antibacterial activity (p<0,05). In addition, of the three gel formulations, F3 showed the best antibacterial activity against Staphylococcus aureus with a strong category of inhibition zone.
Formulasi dan Uji Efektivitas Sediaan Lip cream dari Ekstrak Etanol Biji Buah Merah (Pandanus conoideus L) sebagai Pewarna Alami dengan Menggunakan Metode DPPH (1,1-Difenil-2-Pikrihidrazil) Nur Baetty Primadani; Rugayyah Alyidrus; Nurfiddin Farid; Nielma Auliah
JURNAL FARMASI DAN MAKANAN Vol 7 No 1 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v7i1.4173

Abstract

Formulation and Effectiveness Test of Lip Cream Preparations from Ethanol Extract of Red Fruit Seeds (Pandanus conoideus L) as A Natural Dye Using The DPPH (1,1-Diphenyl-2-Pikrihidrazil) Method. Red fruit seeds are botanical specimens that possess keratenoid chemicals, specifically b-carotene and a-carotene, which exhibit antioxidant properties. The objective of this study is to develop a stable Lipcream formulation and measure the IC50 value of the lipcream prepared from the ethanol extract of red fruit seeds (Pandanus conoideus L), which has antioxidant properties. An experimental research approach utilizing a solvent maceration technique with a solvent concentration of 96%. The obtained concentrated extract was subjected to rotation, followed by the fabrication of solutions with concentrations of 2%, 4%, and 6%, utilizing beeswax as a thickening agent. Kaolin is used as a texturizer. The emollients used are castor oil, cetyl alcohol, and dimethicon. Methyl paraben and propyl paraben are utilized as preservatives. Titanium dioxide serves as a pigment. The scent of vanilla. The preparation was evaluated by a cycling test consisting of 6 cycles over a period of 12 days. Organoleptic observations revealed a semi-solid texture, cream-like form, and a vanilla scent. The homogeneity test yielded consistent results, with pH measurements exceeding 0.05p, spreadability test results surpassing 0.05p, and adhesiveness test results meeting the specified standards. In addition to doing antioxidant testing, the DPPH method is employed using a UV-Vis spectrophotometer. The research findings indicate that the ethanol extract derived from red fruit seeds (Pandanus conoideus L) can be effectively made into a stable lip cream formulation, both in terms of its physical and chemical properties. The IC50 values obtained from the lip cream formulation including the ethanol extract of red fruit seeds (Pandanus conoideus L) were 59,496 ppm, 52,817 ppm, and 5,581 ppm, respectively. Formula 3 contains the most potent antioxidant value among all lip cream preparations.
Formulasi Sediaan Acne Patch Ekstrak Etanol Daun Coleus scutellarioides L. terhadap Propionibacterium acnes dan Staphylococcus epidermidis Abdul Wahid Suleman; Natasya Virginia; Nasrawati Basir; Sriyanty Sadsyam; Chikita Inaku; Nurfiddin Farid
Indonesian Journal of Medical and Pharmaceutical Science Vol. 5 No. 1 (2026)
Publisher : Sultan Agung Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v5i1.566

Abstract

Background: The increasing prevalence of acne vulgaris and the growing resistance of Propionibacterium acnes and Staphylococcus epidermidis to conventional antibiotics have encouraged the development of safer and more effective natural therapies. This study aimed to formulate and evaluate the physical stability of an acne patch containing ethanolic extract of miana leaves (Coleus scutellarioides L.) and to determine its antibacterial activity against P. acnes and S. epidermidis. Methods: Miana leaves were extracted by maceration using 96% ethanol and formulated into acne patches at concentrations of 0.5%, 1%, and 2% using hydroxypropyl methylcellulose (HPMC) as the film-forming polymer. The formulations were evaluated for organoleptic properties, weight uniformity, pH, thickness, moisture content, and stability through a cycling test. Antibacterial activity was assessed in vitro using the agar diffusion method. Results: All formulations exhibited acceptable physical characteristics and remained stable throughout the cycling test. Statistical analysis revealed significant differences in antibacterial activity among the formulations (p < 0.05). The inhibition zones increased proportionally with extract concentration, indicating a concentration-dependent antibacterial effect. The formulation containing 2% miana leaf extract demonstrated the highest antibacterial activity against both P. acnes and S. epidermidis and showed significantly greater inhibition than the lower concentrations (p < 0.05). Furthermore, this formulation maintained satisfactory physical stability and quality parameters. Conclusion: These findings indicate that the 2% miana leaf extract acne patch is the optimal formulation and has potential as a safe, stable, and effective natural anti-acne product.
Co-Authors Abda Abda Abdul Wahid Suleman Ahmad, Fitriani Fajri Aliah, Ahmad Irsyad Andi Bibit Utari Rahayu Andi Ulfiana Utari Azima, Annisa Chikita Inaku Dian Islamiah Dwi Rantisari Thayeb, Andi Meinar Dwi Yulianti Alifah Hilmiati Wahid Hilmiati Wahid Idris, Zulfiah Ika Lismayani Ilyas Inda sari Jangga Kontesa, Emiliana Ansika Latelay, Rio Markasi Muh. Yusuf Wahyuni Hasniar Muhammad Akmal A Sukara Muhammad Arman Muhammad Yusuf Muhammad Yusuf Muhammad Yusuf Murdi, Anna Muthmainna Musdalifa Musdalifa Mutmainnah Siradjuddin Muzayyidah Muzayyidah Muzayyidah Nasrawati Basir Natasya Virginia Nielma Auliah Nur Baetty Primadani Nurfitria Junita Nurhikma Awaluddin Nurjannah Bachri Nurul Inayah Octaviani, Dilha Putri Indah Sari Rahmania Rahmania Rugayyah Alyidrus Rugayyah Alyidrus Rusli, Nurul Azmi Saleh, Adriandy Setiawan, Prayitno Sri Wahyuningsih Sriyanty Sadsyam Sriyanty Sadsyam Suhartina Hamzah Suhenro, Suhenro Suhrah Febrina Karim Sulfiani, Sulfiani Syamsu, Andi Suparlan Isya Syarifuddin, Surya Tamzil Azizi Musdar Ummu Kalsum Ummu Kalsum Wahid, Hilmiati Wahyuli, Resky Wahyuni Irianti Wira Anugrah Yustikawati Yustikawati Yustisi, Juaella