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All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Medula Juke Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Indonesian Journal of Science and Technology Majalah Kedokteran Sriwijaya JURNAL KESEHATAN LINGKUNGAN: Jurnal dan Aplikasi Teknik Kesehatan Lingkungan Jurnal Manajemen Kesehatan Yayasan RS.Dr. Soetomo Jurnal Analis Kesehatan Jurnal Dunia Kesmas Jurnal Ilmu Kedokteran dan Kesehatan JURNAL PENELITIAN PERAWAT PROFESIONAL Jurnal Aisyah : Jurnal Ilmu Kesehatan JK Unila (Jurnal Kedokteran Universitas Lampung) Bioscientia Medicina : Journal of Biomedicine and Translational Research JCOMENT (Journal of Community Empowerment) Jurnal Sylva Lestari Prosiding Seminar Nasional Pengabdian Kepada Masyarakat JUKEJ: Jurnal Kesehatan Jompa Majority JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine
Betta Kurniawan, Betta
Bagian Parasitologi, Fakultas Kedokteran, Universitas Lampung
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Efektivitas Antijamur Ekstrak Etanol Daun dan Akar Beluntas terhadap Pertumbuhan Candida Albicans dengan Metode Spektrofometri Dewayanti, Wahyu; Soleha, Tri Umiana; Himayani, Rani; Kurniawan, Betta
Jurnal Dunia Kesmas Vol 14, No 2 (2025): Volume 14 Nomor 2
Publisher : Persatuan Dosen Kesehatan Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jdk.v14i2.20137

Abstract

Kandidiasis merupakan suatu infeksi yang disebabkan oleh jamur family Candida, biasanya oleh spesies Candida albicans. Tanaman beluntas (family Asteraceae) merupakan salah satu tumbuhan yang mampu mengendalikan penyakit jamur. Tanaman tersebut mengandung senyawa flavonoid, tanin, minyak atsiri, dan alkaloid yang dikenal mampu berfungsi sebagai antiinflamasi, antiulkus, antioksidan dan anti mikroba. Lebih lanjut, akar tanaman beluntas juga memiliki kandungan flavonoid, fenol, proanthocyanidins, dan tannin yang terbukti memiliki efek farmakologis, inhibitor mikroorganisme dan mengurangi risiko infeksi jamur. Penelitian ini bertujuan mengetahui perbedaan daya antijamur ekstrak etanol daun dan akar tanaman beluntas terhadap pertumbuhan candida albicans. Penelitian berbentuk eksperimental murni (true experimental) dengan rancangan berupa post test only control group design. Metode spektrofotometri digunakan untuk mengetahui efek antijamur ekstrak etanol sehingga dapat ditentukan diameter zona hambat, Kadar Hambat Minimum (KHM) dan Kadar Bunuh Minimum (KBM). Hasil penelitian menunjukan adanya efektivitas antijamur ekstrak etanol daun Beluntas konsentrasi 100%, 75%, 50%, 25% dan ekstrak etanol akar tanaman Beluntas (Plucea Indica Less) konsentrasi 100% terhadap pertumbuhan Candida albicans. Ekstrak etanol daun Beluntas memiliki efektivitas lebih baik daripada ekstrak etanol akar tanaman Beluntas dalam menghambat pertumbuhan Candida Albicans.
Larvacidal activity of Illicium verum ethanolic extract against Aedes aegypti Kurniawan, Betta; Saftarina, Fitria; Mustofa, Syazili; Syaka, Muthiiah Khodista
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 10, No 1 (2025): March
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30604/jika.v10i1.3038

Abstract

Background: Chemical larvicides that have been used for a long time carry some risks by causing environmental risk. Besides, temephos has been documented to have the growth of resistance in various regions throughout the world among mosquito populations, consequently decreasing its effectiveness in eliminating the larval stage.  Therefore, developing alternative plant-based larvicides was considered a worthy step to reduce the risk of resistance to chemical larvicides. Illicium verum (IV), a plant-based spice, contains secondary metabolites such as flavonoids, saponins, tannins, and alkaloids acting as larvicidal agents. This study was conducted to attain Illicium verum ethanolic extract as an alternate plant-based mosquito larvicide against the dengue vector Aedes aegypti.Methods: The research design was an experimental method with a post-test-only control group design. The larvicide test in this study was divided into five groups with four repetitions and analyzed by Kruskal-Wallis test, post-hoc Mann-Whitney test, and probit analysis conducted with 95% confidence interval.Results: No significant difference was shown between concentrations of 0.25%, 0.125%, and 1% temephos, which showed a value of p0.05 on the Mann-Whitney test. The probit test showed the LC50 value was 0.476%, and the LC90 value was 2.42% at the maximum observation time. At the highest concentration, the LT50 value was 0.037 hours, and the LT90 value was 0.269 hours.Conclusion: This study reveals that natural substance of Illicium verum ethanolic extract surpassed 1% temephos as a botanical larvicide against Aedes aegypti larvae. This should be an environment-friendly solution to synthetic larvicide resistance.
Analysis of Malathion Insecticide Resistance in Aedes aegypti Mosquitoes Using the CDC Bottle Bioassay Method Kirche, Agnes Angelina; Kurniawan, Betta; Putri, Giska Tri; Mutiara, Hanna
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i1.1376

Abstract

Dengue is an infectious disease transmitted by the Aedes aegypti mosquito, which breeds rapidly in Indonesia's tropical environment, increasing the risk of spreading this disease. Vector control using malathion insecticide can be effective, but repeated use and inappropriate dosage can cause resistance in mosquitoes which ultimately increases the risk of dengue infection. CDC Bottle Bioassay is a test method for evaluating mosquito resistance to insecticides with a standardized procedure and is carried out using bottles containing insecticides with different diagnostic doses. Research using this method shows that Aedes aegypti mosquitoes in various locations show resistance to malathion at certain doses and tolerance at other doses. Several studies have also shown that mosquitoes exposed to malathion show categories of resistance or tolerance based on the mortality rate recorded during the test. Malathion, which is a class of organophosphorus insecticides, works by irreversibly binding to acetylcholinesterase and effectively kills mosquitoes, but repeated use can trigger resistance. Factors influencing resistance include biological factors such as migration, operational factors such as insecticide dosage and application, as well as genetic factors associated with the resistant allele. If mosquitoes carrying resistant alleles move or interbreed, this can increase the resistance status in an area, which is seen in Aedes aegypti populations in several regions of the world.
Pengaruh Perubahan Tutupan Lahan dan Indeks Pembangunan Manusia Terhadap Kejadian TB Paru Di Provinsi Lampung Widianningrum, Wahyu; Bakri, Samsul; Kurniawan, Betta; Darmawan, Arief; Suwandi, Jhons Fatriyadi; Nurcahyani, Nuning; Wulandari, Christine
JUKEJ : Jurnal Kesehatan Jompa Vol 4 No 1 (2025): JUKEJ: Jurnal Kesehatan Jompa
Publisher : Yayasan Jompa Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57218/jkj.Vol4.Iss1.1539

Abstract

Land cover change is one of the major contributors to environmental degradation and can significantly alter the physical environment. These alterations in the physical environment may have substantial implications for human health. One of the notable health impacts associated with such changes is the increased incidence of tuberculosis. Tuberculosis cases are linked to the proliferation of Mycobacterium tuberculosis, which thrives in environments with high humidity levels. This study employs linear regression analysis to examine the influence of various types of land cover—namely, plantation areas, mixed agriculture, residential zones, and rice fields—on tuberculosis incidence. Additionally, the study incorporates Human Development Index (HDI) and economic growth rate as proxies for human development in Lampung Province. The findings, based on t-test statistical analysis, reveal that plantation land cover (P-value = 0.045) and the rate of economic growth (P-value = 0.001) have a statistically significant effect on tuberculosis incidence in the region. In contrast, other land use types and the Human Development Index do not exhibit a significant relationship with the number of tuberculosis cases. Based on these results, it is recommended that the government formulate credible and evidence-based regulations concerning future land use planning.
PENCEGAHAN DIABETES MELLITUS TIPE 2 PADA MASYARAKAT PERKOTAAN DENGAN PROMOSI KESEHATAN DI WILAYAH KERJA PUSKESMAS KEDATON, BANDAR LAMPUNG Pramesona, Bayu Anggileo; Kurniawan, Betta; Iqbal, Muhammad; Triyandi, Ramadhan; Agustine Sesunan, Dyah Surya; Puspitasari, Lia; Budyantara, Ronalda
JCOMENT (Journal of Community Empowerment) Vol. 6 No. 3 (2025): Community Empowerment
Publisher : The Journal Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55314/jcoment.v6i3.1034

Abstract

Prevalensi diabetes Mellitus (DM) pada penduduk ³15 tahun mayoritas berdomisili di perkotaan dengan latar belakang pendidikan rendah. Provinsi Lampung berada pada urutan ke-7 kasus DM tertinggi dari seluruh provinsi di Indonesia untuk kategori semua umur. Kota Bandar Lampung memiliki jumlah penderita DM terbanyak ke-5 se-provinsi Lampung. Sedangkan Puskesmas Kedaton, Bandar Lampung berada pada peringkat ke-3 puskesmas se-Bandar Lampung dengan jumlah pasien DM terbanyak dan cenderung bertambah. Perlu adanya upaya preventif agar prevalensi DM tidak terus meningkat. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pengetahuan dan pemahaman masyarakat perkotaan khususnya kelompok Prolanis DM dalam upaya mencegah terjadinya penyakit DM serta mencegah komplikasi yang diakibatkan oleh penyakit DM. Kegiatan ini dilaksanakan pada 8 Agustus 2025 di Puskesmas Kedaton, Bandar Lampung melibatkan 60 lansia prolanis. Promosi kesehatan dilakukan dengan media promosi kesehatan berupa presentasi PowerPoint, dan buku saku DM. Pre-test dan post-test dilakukan sebelum dan setelah kegiatan untuk mengukur skor pengetahuan peserta. Hasil menunjukkan peningkatan rata-rata skor pengetahuan dari 77,5 menjadi 93,5 (20,6%), dan analisis statistik dengan uji t berpasangan menunjukkan adanya perbedaan signifikan skor sebelum dan setelah diberikan promosi kesehatan (p<0,001). Selain peningkatan kuantitatif skor, kegiatan juga melibatkan partisipasi aktif peserta selama sesi diskusi. Temuan ini mengindikasikan bahwa promosi kesehatan pada layanan primer efektif meningkatkan pengetahuan pencegahan diabetes mellitus pada lansia khususnya di perkotaan dan berpotensi mendorong adopsi perilaku preventif, sehingga direkomendasikan replikasi dan penguatan jejaring rujukan untuk tindak lanjut individu berisiko.
Efektivitas Program Pemberantasan Penyakit Demam Berdarah Dengue Nurmumpuni, Dwita; Kurniawan, Betta; Suharmanto, Suharmanto
Jurnal Penelitian Perawat Profesional Vol 6 No 3 (2024): Juni 2024, Jurnal Penelitian Perawat Profesional
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jppp.v6i3.2423

Abstract

Risiko masyarakat terhadap demam berdarah juga bergantung pada pengetahuan, sikap dan praktik masyarakat terhadap demam berdarah, serta pelaksanaan kegiatan rutin pengendalian vektor berkelanjutan di masyarakat yang digalakkan oleh pemerintah. Tujuan review ini adalah untuk menguraikan efektivitas program pemberantasan DBD. Review artikel ini dilakukan dengan cara mencari artikel pada database Google Scholar dan Pubmed dengan menggunakan kata kunci “efektivitas program”, “pemberantasan” dan “demam berdarah dengue”. Artikel yang didapatkan sebanyak 17 artikel dan 6 artikel memenuhi syarat untuk dilakukan analisis. Peneliti membuat rangkuman dan melakukan interpretasi dari masing-masing hasil penelitian. Berbagai upaya pencegahan DBD telah dilakukan di Indonesia maupun negara-negara lainnya. Pada umumnya, program pencegahan pengendalian DBD di setiap negara meliputi pengendalian vektor dan program edukasi untuk masyarakat terkait gejala DBD dan cara pencegahannya. Berbagai program juga telah diimplementasikan untuk memberantas penyakit demam berdarah dengue (DBD), namun dalam pelaksanaannya masih terdapat hambatan-hambatan dari aspek input, proses, dan output. Program ini juga masih belum optimal karena belum memenuhi standar Angka Bebas Jentik sebesar 95%.
A Case Report: Severe Chronic Obstructive Pulmonary Disease (COPD) Exacerbation Due To Community-Acquired Pneumonia (CAP) Infection In Smokers Mustofa, Syazili; Anggraeni, Liza; Putri, Giska Tri; Kurniawan, Betta; Agung Kurnia, Ahmad Fadila
Jurnal Ilmu Kedokteran dan Kesehatan Vol 12, No 1 (2025): Volume 12 Nomor 1
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v12i1.16265

Abstract

COPD, also know as Chronic Obstructive Pulmonary Disease, refers to a lung condition marked by persistent and progressive airflow blockage. This is usually the result of a chronic inflammatory reaction in the respiratory tract brought on by exposure to harmful gases or particles. Respiratory tract infections like Community-Acquired Pneumonia (CAP) frequently cause COPD exacerbations, while smoking is the main risk factor that contributes to the onset and worsening of COPD. The goal of this case report is to provide an understanding of the underlying mechanism of severe COPD cause by CAP infection in smokers and to diagnose and manage the condition effectively. A 72-year-old man complained of shortness of breath that he had been having for the last year, and that had worsened over the previous three days when he arrived at the emergency unit of Abdoel Moeloek Hospital in Lampung. In addition, he also had a fever and severe cough with yellow sputum. Following a comprehensive review of medical history, physical examination, and supporting examination, it was concluded that a CAP infection was linked to severe COPD exacerbation. The patient received antibiotic medication and hospitalization treatment for symptomatic therapy.
Mortality Test Of Spice Plants As Biolarvicides Against Aedes Aegypti Larvae: Literature Review Syaka, Muthiiah Khodista; Kurniawan, Betta; Saftarina, Fitria
JURNAL KESEHATAN LINGKUNGAN: Jurnal dan Aplikasi Teknik Kesehatan Lingkungan Vol 22 No 1 (2025): Jurnal Kesehatan Lingkungan Volume 22 No. 1, Januari 2025
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Kesehatan Lingkungan Banjarbaru

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/jkl.v22i1.902

Abstract

Dengue hemorrhagic fever (DHF) remains a global public health issue, transmitted through the bite of the Aedes aegypti mosquito. One method of disease prevention is the use of insecticides in the form of larvicides. Chemical larvicides have long been used but carry the risk of inducing resistance; therefore, research into the development of alternative larvicides is necessary. Indonesia’s rich biodiversity of spices presents a promising opportunity for the development of spice-based biolarvicides. This study was conducted in the form of a literature review, aiming to provide an overview of mortality tests of spice plants as biolarvicides against Aedes aegypti larvae. The findings from the reviewed literature indicate that two spices—tobacco leaves (Nicotiana tabacum) and zodia leaves (Evodia suaveolens)—in ethanol extract form achieved 100% larval mortality at all tested concentrations. The review also identified a variety of other spices with potential as biolarvicides based on larvicidal tests, with 9 out of 20 spices exhibiting 100% larval mortality rates in the summarized studies. It can thus be concluded that various spice plants demonstrate significant mortality test results and hold potential as alternative biolarvicides against Aedes aegypti larvae. Continued efforts to conduct standardization tests on these spice plants are necessary to develop them into standardized biolarvicidal agents.
ACNE VULGARIS BERBASIS PATOGENESIS Centya Cheirini; Hendra Tarigan; Aditya, Muhammad; Kurniawan, Betta
Medula Vol 14 No 10 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i10.1308

Abstract

Acne vulgaris is a chronic inflammatory disease characterized by polymorphic lesions in the form of comedones, papules, pustules, nodules & cysts in predilection locations. Acne vulgaris is the third most frequent case of the 10 most common skin diseases that often come to health services. The incidence of acne vulgaris can occur due to various factors, including increased androgen hormones, increased sebum production and excessive growth of the Cutibacterium acne bacteria. Cutibacterium acnes bacteria play a role in the inflammatory process which increases the worsening of skin conditions with the enzymes and pro-inflammatory factors produced. Young people are the age who suffer from acne vulgaris more often (85%) with a range of 12-25 years. The diagnosis of acne vulgaris is generally easy to make but therapy results are often unsatisfactory. Medications that are often involved in treating acne vulgaris are the use of topical and systemic antibiotics, retinoids, and anti-clindamycin agents. The purpose of this review article is to find out more about acne vulgaris based on pathogenesis. It is hoped that a deeper understanding of the pathogenesis of acne vulgaris will be able to provide much better therapeutic options, resulting in optimal improvements in acne vulgaris therapy.  
Pemeriksaan Kadar Asam Urat dan Penyuluhan tentang Penyakit Gout pada Masyarakat di Desa Kalisari Kecamatan Natar Kabupaten Lampung Selatan Susianti, Susianti; Kurniawan, Betta; Zuraida, Reni; Mutiara, Hanna
JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Vol. 1 No. 1 (2015): JURNAL PENGABDIAN MASYARAKAT RUWA JURAI
Publisher : FK Unila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpmrj.v1i1.1149

Abstract

Penyakit gout adalah salah satu tipe dari arthritis (rematik) yang disebabkan terlalu banyaknya atau tidak normalnya kadar asam urat di dalam tubuh. Di masyarakat beredar mitos bahwa ngilu sendi berarti penyakit asam urat. Pengertian ini perlu diluruskan, sehingga dirasa perlu untuk melakukan penyuluhan dan perlu dilakukan pemeriksaan kadar asam urat. Kegiatan dilaksanakan pada tanggal 15 November 2015 pukul 15.30 s.d. 17.30 WIB di Desa Kalisari Kecamatan Natar Kabupaten Lampung Selatan dan dihadiri 31 orang warga yang didominasi oleh ibu-ibu rumah tangga. Metode yang digunakan dalam kegiatan ini adalah penyuluhan yang dilanjutkan dengan diskusi. Evaluasi yang dilakukan terdiri dari evaluasi awal (pre-test), evaluasi proses (pertanyaan saat diskusi) dan evaluasi akhir (post-test). Berdasarkan data hasil pengamatan diperoleh rata-rata nilai pre-test peserta 45,61 dan post-test 65,37. Setelah mendapatkan penyuluhan mengenai penyakit gout,terdapat peningkatan pengetahuan masyarakat di Desa Kalisari Kecamatan Natar Kabupaten Lampung Selatan tentang penyakit gout. Setelah dilakukan penyuluhan, masing-masing peserta diperiksa kadar asam urat dalam darah yang diambil dari darah perifer dan diperiksa menggunakan stick. Dari hasil pemeriksaan didapatkanbahwa dari 31 orang peserta dan 10 orang yang memiliki kadar asam urat di atas normal. Itu berarti angka kejadian gout di desa Kalisari cukup tinggi. Terdapat peningkatan pengetahuan masyarakat di Desa KalisariKecamatan Natar Kabupaten Lampung Selatan tentang penyakit gout. Angka kejadian penyakit gout di Desa Kalisari Kecamatan Natar Kabupaten Lampung Selatan sendiri cukup tinggi.
Co-Authors A.A. Ketut Agung Cahyawan W Abda Abda Abigail Pheilia Ade Triajayanti Ade Yonata, Ade Aditya Permana Agung Kurnia, Ahmad Fadila Agustine Sesunan, Dyah Surya Aila Karyus Ali Rahmat Alvin Widya Ananda Andriana, Bibin B. Anggi Setiorini Anggraeni Janar Wulan, Anggraeni Janar Anggraeni, Liza Anniza Agustina Apga Repindo Arief Darmawan Asep Sukohar Bayu Anggileo Pramesona Cahaya Carla Bangsawan Centya Cheirini Christine Wulandari Dewayanti, Wahyu Dian Isti Angraini Dwi Indria Anggraini Dwita Oktaria Dyah Wulan Sumekar Rengganis Wardani Dyah Wulan Sumekar Rengganis Wardani Efrida Warganegara Endah Setyaningrum Etty Widyastuti Ety Apriliana Evi Kurniawaty Fadli, Muhammad Yogie Firdha Yossi Chani Fitria Saftarina Fitria, Saftarina Giska Tri Putri Hadibrata, Exsa Haekal Alfhad Hamzah, Muhammad Syafei Hanna Mutiara Hanna Mutiara Hanna Mutiara Hanna Mutiara, Hanna Hendra Tarigan Hijami, Nurul 'Afifah Husna, Ismalia I Wayan Dika Aditia Darma Ika Yunidasari Indah Anita Dewi Jausal, Anisa Nuraisa jefri irawan Jermsittiparsert, Kittisak Jhons Fatriyadi Suwandi Kartika, Juspeni Keisha Azzahra Tetadrian Khairun Nisa Kirche, Agnes Angelina Kurnia, Yogi Kurniawaty, Evi Laila Puspita M. Ridho Ulya M. Yusran Merry Indah Sari Muatiara, Hanna Muhammad Aditya, Muhammad Muhammad Iqbal Muhammad Ricky Ramadhian Muhammad Yusran Muhartono Muhartono Nani Indah Hardiyanti Novita Carolia Nuning Nurcahyani Nurmumpuni, Dwita Nurul Islamy Nurul Sahana Rahmadhini Nurul Utami Nurul Utami Otta Nur Kirana Putra, Agung Kartika Rahmatullah Rayman Rani Himayani Reni Zuraida Ria Rizki Jayanti Rika Lisiswanti Risal Wintoko Risti Graharti Riyan Wahyudo Rizki Hanriko Rizqa Atina Rodiani - Rofiqul Umam Ronalda Budyantara Sa'diyah, Isma Fadlilatus Samsul Bakri Samsul Bakri Samsul Bakri Selvi Marcellia Septilia Sugiarti Septyne Rahayuni Putri Sri Janahtul Hayati Sri Puji Hartini Suharmanto Suharmanto Suharmanto Susianti Susianti Sutyarso Sutyarso Sutyarso Suwandi, Jhons F. Suwandi, Jhosn Fatriyadi Suyatno Suyatno Syaka, Muthiiah Khodista Syazili Mustofa Tri Umiana Soleha Tri Umiana Soleha Triyandi, Ramadhan Ulima Mazaya Ghaisani Utari Gita Mutiara Wardani, Ika Novianna Widianningrum, Wahyu Zahra Dewi Hasna Difa