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All Journal Jurnal Ilmiah Farmasi Pharmaciana: Jurnal Kefarmasian Jurnal Surya Medika Indo-MathEdu Intellectuals Journal International Journal of Science and Society (IJSOC) Jurnal Kesehatan dan Pengelolaan Lingkungan Jurnal Lingkar Mutu Pendidikan Jurnal Ilmiah Pengabdian dan Inovasi Riemann : Research of Mathematics and Mathematics Education Journal Of Medicine And Health Sciences (Medisci) Murabbi: Pendidikan Guru Madrasah Ibtidaiyah Hexagon: Jurnal Ilmu dan Pendidikan Matematika Scientific Development Journal Indonesian Journal of Jamu
Kintoko
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Exploration of the Function of Galactagogue in Fenugreek, Moringa, and Sauropus Androgynus Polyherbal Tea: Systematic Literature Review Eva Kusumahati; Kintoko; Sagiran
Side: Scientific Development Journal Vol. 2 No. 6 (2025): Side: Scientific Development Journal
Publisher : Arbain Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59613/qjxqeb61

Abstract

This study aims to evaluate the effect of polyherbal tea consisting of fenugreek, Moringa oleifera, and Sauropus androgynus on breast milk production and quality, as well as the health of breastfeeding mothers. The method used was a Systematic Literature Review (SLR) based on PRISMA 2020, where studies were identified through a systematic search in the Scopus database using relevant keywords. Data were extracted from studies that met the inclusion criteria and were evaluated to determine the effectiveness and safety of polyherbal teas. The results showed that polyherbal tea supplementation has the potential to increase breast milk production by stimulating the hormones prolactin and oxytocin. Fenugreek and Moringa oleifera significantly increase milk production and change the nutritional profile of breast milk for the better, including increased unsaturated fatty acid content and antioxidant capacity. Sauropus androgynus leaves also show potential as galactogogues and maternal health supporters. In addition, this herbal supplementation provides additional benefits for maternal health, such as improved nutritional status and reduced fatigue. These findings are important because they provide stronger scientific evidence to support the use of herbal supplements in clinical practice, as well as suggesting that polyherbal teas can be an effective natural alternative in improving milk production and quality and supporting the health of breastfeeding mothers. Further research is needed to determine the optimal dosage and long-term effects of these herbal supplements, as well as to understand the synergistic interactions between the herbal ingredients. Relevant keywords for this study included: polyherbal tea, galactagogue, breast milk production, breast milk quality, fenugreek, Moringa oleifera, Sauropus androgynus, and breastfeeding maternal health.
Characterization and The Effects Analysis of Purple-fleshed Sweet Potato Extract (Ipomoea batatas [L.]) Administration on Triglyceride Concentration and Pancreatic Histopathology Profiles of Triton X-100-induced Hyperlipidemia in Rats Kintoko; Hardi Astuti Witasari; Rizky Nurdhillah; Tsania Taskia Nabila
Jurnal Jamu Indonesia Vol. 7 No. 2 (2022): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v7i2.258

Abstract

Hypertriglyceridemia occurs when the triglyceride levels are increasing from the normal (>150 mg/dL) and it causes pancreatitis at a dose of more than 885 mg/dL. The triglyceride-lowering medicines consumption has several side effects on various organ systems. The plant-based medicine (phytomedicine) alternatives have been observed as the synthetic medicine substitution. Purple-fleshed sweet potato (Ipomoea batatas [L.]) contains anthocyanin that has proven to carry out the antioxidant mechanism and the capability to be used as anti-hypertriglyceridemia. This study aims to identify the activity of purple-fleshed sweet potato extracts on triglyceride levels and the histopathological profile of rats' pancreas-induced Triton X-100. Twenty-five male Wistar rats of week 8th were divided into five groups. The normal (N) group was treated with saline solution, and the treatment (T) groups were a single dose of 100 mg/kg of body weight (BW) Triton X-100 and purple-fleshed sweet potato extracts of 175 (T1); 350 (T2); and 700 (T3) mg/kg BW, while the negative (C-) control group was mere induced by a single-dose Triton X-100 of 100 mg/kg BW. The blood serum was isolated and the pre-and post-test was subsequent conducted. The triglyceride serum levels and histopathological data were analyzed by the Kolmogorov-Smirnov normality test and Kruskal-Wallis post-test statistical analysis. The results showed that Triton X-100-induced treatment could significantly increase the triglyceride levels compared to the normal group (P<0.05). The purple-fleshed sweet potato extracts started to lower the triglyceride level at a dose of 700 mg/kg BW (51.83 ±19.15(%)). The extract doses of 175 and 350 mg/kg BW could not reduce the triglyceride level significantly (3.03±2.77 and 5.63±4.24 (%), respectively). A dose of 700 mg/kg BW did not damage the exocrine gland and Langerhans islet of hyperlipidemia rat pancreas treated by Triton X-100. 
Ethnopharmacology, LC-MS profiling, and molecular docking of diarrheal-healing plants by the Osing tribe Cendekiawan, Khrisna Agung; Kintoko; Yuliani, Sapto; Wardhani, Firdha Aprillia
Pharmaciana Vol. 15 No. 3 (2025): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v15i3.31315

Abstract

Indonesia has a long history of using medicinal plants, but much of this knowledge, especially among groups like the Osing people in East Java, is not well-documented. This study looks at the plants used by the Osing community to treat diarrhea. This research was conducted through interviews with residents of Banjar and Licin Villages in Banyuwangi Regency. The significance and perceived efficacy of each medicinal plant were evaluated using the ethnobotanical indices Use Value (UV) and Fidelity Level (FL). They also did tests to find the active chemicals in the plants. The most common plants for treating diarrhea were Psidium guajava (UV = 2.44) and Piper betle (UV = 1.11). Psidium guajava had the highest FL value (64.7%). Tests have shown that these plants contain essential chemicals. Further analysis confirmed the presence of quercetin and kaempferol, which are known to help alleviate stomach problems. To support these findings, computer-based tests were done, including Lipinski rule prediction, ADMET profiling, and molecular docking. The results showed quercetin binds well (ΔG = -9.72) and has a good RMSD value (1.83 Å). This suggests quercetin could be a good starting point for making antidiarrheal drugs. Overall, the study underscores the significance of traditional knowledge and recommends further research on plant-based treatments for stomach issues.
Research Trends in Ethnomedicine-Based Anti-Diabetic Medicinal Plants: A Bibliometric Analysis (2010–2025) Wiwik Rahayu; Kintoko; Sagiran; Muhammad Yulis Hamidy
Jurnal Surya Medika (JSM) Vol. 12 No. 1 (2026): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v12i1.12967

Abstract

Studi ini bertujuan untuk mengindentifikasi dan memulai penelitian tentang tanaman obat anti-diabetes berbasis etnomedis. Studi ini selain menggunakan analisis bibliometrik, juga memanfaatkan perangkat lunak VOSviewers untuk memvisualisasikan jaringan, tren, dan karakteristik penelitian tentang tanaman obat dalam 15 tahun terakhir berbasis database Scopus. Dari penemuan 116 jumlah total dokumen publikasi penelitian tanaman obat dalam 15 tahun terakhir, negara India, Nigeria, Bangladesh, menjadi negara paling aktif dalam penerbitan penelitian tanaman obat dalam 15 tahun terakhir. Universitas University of Nigeria, University of Development Alternative, dan University of Ibadan menjadi afiliasi terbanyak dalam mempublikasikan penelitian tanaman obat. Mohammed Salim Rahmatullah dari Bangladesh, Rainer W. Bussmann dari Georgia, dan Rownak Jahan dari Bangladesh menjadi penulis paling konsisten mempublikasikan penelitian tanaman obat dalam 15 tahun terakhir. Studi ini juga merekomendasikan pentingnya studi-studi di masa yang akan datang untuk membahas potensi kandungan senyawa dalam tanaman obat, khususnya dalam konteks penanganan penyakit kronis seperti diabetes.
Co-Authors Astutik, Wiwin Dwi Botutihe, Lisa Agustina Eva Kusumahati Fitriana, Eni Hadi Siswanto, Deny Hardi Astuti Witasari Ibrozi, Hardi Astuti Witasari IIN INDAWATI Khrisna Agung Cendekiawan Muhammad Yulis Hamidy Nuryanto, Abid Nuryanto, Edy Oktaviani, Tristine Pertiwi, Yuniariana Putri, Nadia Maharani Ramadhanie, Bella Rizky Nurdhillah Rohmah, Lely Arbiati Nur Safira, Rizka Sagiran Sapto Yuliani Siswanto, Deny Hadi Suliyanto Sunanti, Titis Susetyawati , M.M. Endang Susetyawati, M.M. Endang Tsania Taskia Nabila Wahyu Titis Lestariningrum Wardhani, Firdha Aprillia Wiwik Rahayu YULIANA, SARI