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All Journal Jurnal Biotek Majalah Farmasetika Jurnal Ilmiah Farmasi Farmasyifa Budapest International Research and Critics Institute-Journal (BIRCI-Journal): Humanities and Social Sciences Jurnal Ilmiah Agribios Jurnal Kebidanan, Keperawatan dan Kesehatan (J-BIKES) Journal of Pharmaceutical and Sciences. Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Ulil Albab
Winata, Hanafis Sastra
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

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Inflammatory Activity Test of N-Hexant Extract of Kandis Acid (Garcinia Xanthochymus) Against Male White Mice (Rattus norvegicus) Winata, Hanafis Sastra; Hafiz, Ihsanul; Kartika, Yulis; Sihombing, Delima
Budapest International Research and Critics Institute (BIRCI-Journal): Humanities and Social Sciences Vol 4, No 3 (2021): Budapest International Research and Critics Institute August
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birci.v4i3.2290

Abstract

Kandis acid (Garcinia xanthochymus) belongs to the genus Garcinia plants scattered in the tropics of Asia. The fruit is widely used as a flavoring dish by the Malay people. Based on research that has been done on the genus Garcinia, it is known that the largest active compound is the santon group. The research used is experimental. The sample in this study was a male white mouse. Anti-inflammatory activity test was conducted on test animals divided into 5 groups, each amounting to 5 heads with suspension test group N-hexan extract of kandis acid fruit dose 200, 400, 800 mg/kg bb, negative control group is CMC Na 1% susspence and positive control is Na diclofenac 2.25 mg/kg bb. Observations were made for 6 hours then the data was analyzed with a one way annalissys of variance (ANOVA) test. Research showed kandis acid extract (Garcinia xanthochymus) was shown to provide anti-inflammatory effects in male white mice induced caragenan at a dose of 200 mg / kgbb with an average value of udem decrease of 5.25, 400 mg/kgbb with an average udem decrease of 5.17 and 400mg/kgbb with an average udem decrease of 6.08, with the most effective dose in anti-inflammatory reduction being 400 mg/kgbb. The most effective dose of candis acid extract (Garcinia xanthochymus) in anti-inflammatory reduction in male white mice was the dose of kandis acid extract (Garcinia xanthochymus) 400 mg/kgbb. It is recommended to the next researcher to conduct fractionation research on kandis acid fruit plants..  
Analysis of Kandis Acid as a Study of Science and Socio-Cultural Benefits in Society Hanafis Sastra Winata; Khairani Fitri; Rani Monalisa Hutagaol; Hafizhatul Abadi
Budapest International Research and Critics Institute (BIRCI-Journal): Humanities and Social Sciences Vol 5, No 1 (2022): Budapest International Research and Critics Institute February
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birci.v5i1.3624

Abstract

The main ingredient of kandis acid is the asam padeh part, which is a typical Indonesian food that has a sour and spicy taste and is then processed into instant spices. This study aims to analysis of kandis acid as a study of science and socio-cultural benefits in society. This study used descriptive analysis and the disc diffusion method using several concentrations of ethanol extract of kandis acid leaves, namely 15%, 25%, and 35%, positive control 1% chloramphenicol (w/v), and 1% (v/v) DMSO negative control. The diameter of the inhibition zone produced in the test of ethanol extract from kandis acid leaves against Staphylococcus aureus bacteria, respectively: 10.73 mm; 11.61 mm; 12.98 mm and 25.5 mm for positive control, while for Escherichia coli bacteria, namely: 6.11 mm; 8.16mm; 10.85mm; and positive control 22.75 mm. The results of statistical tests showed that there was a significant difference, meaning that the concentration had an effect on the inhibition zone formed. In conclusion, the ethanolic extract of kandis acid leaves has antibacterial activity against the growth of Staphylococcus aureus and Escherichia coli bacteria. The instant asam padeh seasoning is made from a mixture of various spices and also kandis acid which has a yellowish-orange color.
Co-Authors Abadi, Hafizhatul Adek Chan Adek Chan Afriadi Afriadi Aris Ma'ruf Bayu Irvia Satria BENNI ISKANDAR Ekawaty Suryani Mastari Faadhilah Yusa Simbolon Fahmi Irsan Nasution Faisal , Hendri Faisal, Hendri Firman Rezaldi Gumilar, Roni Hendri Faisal Hendri Faisal Hendri Faisal Ihsanul Hafiz Ika Julianti Tambunan Indra Ginting izar, Shaflina Kartika, Yulis Khairani Fitri Leny Leny, Leny Luthvia, Luthvia Masturi, Siti Intan Mayang Sari Mayang Sari Melia Sari Muhammad Amin Nasution Muhammad Andry Muhammad Natsir Ilvira MUHAMMAD RIZAL Naziyah, Syifa Ngete, Ani Florida Nidawah Nidawah Nurjanah, Ayu Nurul Aulia Pamungkas, Barolym Tri Panjaitan, Yuli Cahyani Parhan Parhan Rani Monalisa Hutagaol Sahrita Sahrita Sihombing, Delima Siska Dwi Anggraeni Sitanggang, Joanna Siti Fatimah Hanum Siti Intan Masturi Suprianto Suprianto Vivi Eulis Diana Widya Atika Yudianto, Tri