Article Per Year (5 Year)
p-Index From 2021 - 2026
1.971
P-Index
This Author published in this journals
All Journal Jurnal Agronomi Indonesia (Indonesian Journal of Agronomy) Jurnal Hortikultura Indonesia (JHI) JURNAL GIZI INDONESIA Jurnal Hortikultura Jurnal Agro Ekonomi Jurnal Ilmu-Ilmu Pertanian Indonesia AGRIVITA, Journal of Agricultural Science AGRITEPA: Jurnal Ilmu dan Teknologi Pertanian TERRA : Journal of Land Restoration AGRITROPICA : Journal of Agricultural Sciences Agritrop : Jurnal Ilmu-Ilmu Pertanian (Journal of Agricultural Science) Akta Agrosia Jurnal Agro Ekonomi
Herison, Catur
Jurusan Budidaya Pertanian, Fakultas Pertanian, Universitas Bengkulu
Agriculture, Biological Sciences & Forestry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Environmental Science Health Professions Industrial & Manufacturing Engineering Materials Science & Nanotechnology

Published : 39 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : JURNAL GIZI INDONESIA

 1 
Identification of lactic acid bacteria from lemea's to lower blood sugar levels in mice's diabetes mellitus Okfrianti, Yenni; Herison, Catur; Fahrurrozi, Fahrurrozi; Budianto, Budianto; Okticah, Anggi; Sari, Miliza Mayang
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 13, No 2 (2025): June
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jgi.13.2.117-123

Abstract

Background: Diabetic is one of the main health problems in society throughout the world, so alternatives are needed to help prevent increasing blood sugar levels. In this case, lactic acid bacteria (LAB) are able to inhibit the performance of the alpha glucosidase enzyme in breaking down carbohydrates into glucose, lowering blood sugar levels so that lactic acid bacteria have potential in controlling hyperglycemia.Objectives: The purpose of this work is to assess the potential of four different strains of Lactobacillus that were isolated from lemea to reduce blood sugar levels in mice.Materials and Methods: This study used a pre-test, post-test, control group design for its experimental methodology. Six groups of 18 male mice, aged between 10 and 12 weeks, with body weights ± 25 g each, were formed,three mice comprised each group. This study was divided into 6 treatment groups, namely 1 group given acarboce, 1 group without treatment (aquadest), and 4 treatment groups given 4 types of pure BAL culture. Treatment consisted of P1 (giving L plantarum B1), P2 (giving L plantarum B2), P3 (giving L plantarum S1), and P4 (giving L fermentum S2). The initial stage of the research was to measure the initial fasting blood sugar of the mice, then alloxan was induced at a dose of 4.54 mg/kg BW and given intravenously at 0.1/10 g BW to the mice. After 5 days of alloxan induction, the fasting blood sugar level was measured again. If the blood sugar level was ≥ 127 mg/dL, the mice were declared DM and ready to be given treatment. The dose of acarbose was 0.65 mg/kg bw, and BAL culture with a concentration of 10 8 CFU/mL of 0.1 mg/ 10 g bw for 14 days every 7 days analyzed the blood sugar levels of the mice.Results: The results of the study showed that giving pure culture of L. plantarum from Betung bamboo shoot lemea to mice with type 2 diabetes mellitus (type 2 DM) as treatment P2 was superior to giving acarbose, P1, P3, and P4 in reducing blood sugar levels with pancreatic damage 50% and lower than other treatments, while the pancreas of type 2 DM mice without therapy had the greatest damage score based on histopathological data.Conclusion: Lactic acid bacteria from Lemea can help lower blood sugar levels and prevent the rate of damage to the pancreas of diabetic mice, with the best culture being L. plantarum from Lemea Betung bamboo shoots
Co-Authors , Rustikawati ,, Rustikawati A.A. Ketut Agung Cahyawan W Adeputri, Eriana Agus Purwito Almunawar, Said Agil Alnopri Andria, Andria Angraini, Dila Anira, Rayuli Arifin Noor Sugiharto Atang Sutandi Atra Romeida Bertham, Yudhy H Budianto Budianto Budianto Budianto Budiyanto Budiyanto Dewi, Kurnia Herlina Dwi Wahyuni Ganefianti, Dwi Wahyuni Dwitama, Niko EDHI TURMUDI Eko Suprijono Fahrurrozi Fahrurrozi Fahrurrozi, Fahrurrozi Hairani, Putri Mian Hasanudin Hasanudin Hasanudin Hellianti Pennita Herlinda, Puput HESTI PUJIwATI Hutabarat, Grace May Sawita Indres, Indres Joko Suharjo, Usman Kris Laksono Trisnantoro Maemunah Maemunah Marulak Simarmata Marulak Simarmata Marwanto Marwanto Merakati Handajaningsih Merakati Handajaningsih Merakati Handayaningsih Mimi Sutrawati Muhammad Chozin, Muhammad Mukhtasar, Mukhtasar Nabila, Athya Kania nFN Thamrin Noor Farid Novrika, Donda Nurjanah, Uswatun Nursalim Nursalim Nurwita Dewi Okticah, Anggi Reny Herawati Ria Meita Rustikawati Rustikawati Rustikawati Rustikawati Saputra, Pringky Okta Sari, Miliza Mayang Sari, Rossi Anandayu Sianipar, Mangara W Sigit Sudjatmiko, Sigit Simanihuruk, Bilman Wilman Sudarsono Suharjo, Usman K.J. Suharjo, Usman Kris Joko Sukisno Sukisno Sukisno Sukisno, Sukisno Sulastrini, Ineu Surjono H. Sutjahjo Surjono H. Sutjahjo Surjono H. Sutjahjo Surjono Hadi Sutjahjo Surmaini, Ervi Suryati, Dotti Sutjahjo, Surjono H. Suyitman Suyitman Suyitman, Suyitman Syakia Kurin, Aricha Thamrin, nFN Tunjung Pamekas, Tunjung Viona Juanda Putri Wuri Prameswari Yenni Okfrianti Yulian, Yulian Zainal Muktamar