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BIOAKTIVITAS ZAT EKSTRAKTIF KULIT Acacia auriculiformis A. Cunn. ex Benth. TERHADAP RAYAP TANAH (Coptotermes curvignathus Holmgren) Yanti Hikma; Wasrin Syafii; IGK Tapa Darma
Tengkawang : Jurnal Ilmu Kehutanan Vol 2, No 2 (2012): Jurnal Tengkawang
Publisher : Universitas Tanjungpura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26418/jt.v2i2.3138

Abstract

This research was undertaken mainly to isolate and identify antitermitic substances that may be prospective as wood natural preservative from the bark of Acacia auriculiformis A. Cunn. ex Benth. The woodmeal of the samples were extracted with acetone. The acetone extract was then fractionated into n-hexane soluble fraction, ethyl ether soluble fraction, ethyl acetate soluble fraction, and insoluble fraction. The antifeedant bioassay test was carried out by treating paper discs with extracts at six level of concentration i.e. 0%, 2%, 4%, 6%, 8%, and 10% (w/w). The bioassay test revealed that ethyl ether soluble fraction exhibited high toxicity to subterranean termite Coptotermes curvignathus Holmgren (concentration of 4% has been indicated very strong activity). Keywords: Bioactivity, extractives, Acacia auriculiformis, termites, Coptotermes curvignathus
Leukocyte Profile of Mice Infected with Plasmodium berghei and Treated with Aqueous Extract of Strychnos Ligustrina and Its Combination with Dihydroartemisinin Piperaquine Phosphate (DHP) Umi Cahyaningsih; Siti Sa'diah; Wasrin Syafii; Rita Kartika Sari; Arifin Budiman Nugraha
Jurnal Sain Veteriner Vol 41, No 3 (2023): Desember
Publisher : Faculty of Veterinary Medicine, Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.88896

Abstract

Malaria is still one of the most highly pathogenic diseases, which remains a significant problem for public health. Natural compounds are alternative ways as an antimalarial compound that are applied for the artemisinin combination. The aim of this study was to determine the effect of a combination of S. ligustrina extract and DHP on the differential leukocytes percentages. This study used 100 mice which were divided into five groups. Group A and B were used for the healthy mice and infected-untreated groups, respectively. Group C used as a controlled drug, received 222 mg/kg BW of DHP. Group D received 300 mg/kg BW of aqueous extract of S. ligustrina. Group E received a combination between 111 mg/kg BW of DHP and 200 mg/kg BW of aqueous extract S. ligustrina. The findings demonstrated that DHP and S. ligustrina extract had an impact on neutrophils, lymphocytes, inhibition, and percentages of parasitemia. The findings revealed that treatment groups C, D, and E reduced the percentage of parasitemia. The percentage of neutrophils in treated groups was significantly higher than in group A (P<0.05). The percentage of lymphocytes was lower in the treated groups, while the percentages of eosinophils, monocytes, and basophils did not significantly different (P<0.05). This study found that group D and E had the same effect on the leucocyte profile as group C. Our findings suggest that the aqueous extract of S. ligustrina, as well as the combination treatment with DHP, have the potential to lead to the discovery of new antimalarial medicines.
Antifungal Activity and Identification of Active Compounds From Wood Tristaniopsis whiteana (Griff) Against Wood Rot Fungus Jemi, Renhart; Syafii, Wasrin; Febrianto, Fauzi; Hanafi, Muhammad
Wood Research Journal Vol 15, No 1 (2024): WOOD RESEARCH JOURNAL
Publisher : Masyarakat Peneliti Kayu Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51850/wrj.2024.15.1.28-35

Abstract

The aim of the study was to analyze the content of pelawan wood extractive substances (Tristaniopsis whiteana (Griff)) and to test it with the fungi Schizophyllum commune Fr and Pleurotus ostreatus. Pelawan heartwood powder was macerated with methanol. Then fractionated in stages with n-hexane, chloroform, ethyl acetate, and butanol. The resulting extract was then tested with S. commune and P. ostreatus fungi. The most active fraction was isolated using column chromatography with a gradient system, the eluent was methanol:chloroform. Sub-fractions were then tested for fungi to determine the most active sub-fractions, and the most active sub-fractions were then analyzed by 1H NMR. The results showed that the extractive content of pelawan wood was most soluble in chloroform. All extract fractions contain potential as anti-fungal. .The chloroform fraction was very active compared to the other fractions. Isolation of the chloroform fraction by column chromatography obtained 8 sub-fractions. All of these sub-fractions were able to inhibit the growth of S.commune and P.ostreatus with IC(50) = 54.55 - 64.69 mg/L and IC(50) = 54.17 - 64.44 mg/L respectively. PL.3 sub-fraction was the most active among the 8 sub-fractions. The results of 1H NMR analysis on the PL.3 subfraction were shown to be Heptanoic Acid compounds.
Antifungal Activity and Identification of Active Compounds From Wood Tristaniopsis whiteana (Griff) Against Wood Rot Fungus Jemi, Renhart; Syafii, Wasrin; Febrianto, Fauzi; Hanafi, Muhammad
Wood Research Journal Vol 15, No 1 (2024): WOOD RESEARCH JOURNAL
Publisher : Masyarakat Peneliti Kayu Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51850/wrj.2024.15.1.28-35

Abstract

The aim of the study was to analyze the content of pelawan wood extractive substances (Tristaniopsis whiteana (Griff)) and to test it with the fungi Schizophyllum commune Fr and Pleurotus ostreatus. Pelawan heartwood powder was macerated with methanol. Then fractionated in stages with n-hexane, chloroform, ethyl acetate, and butanol. The resulting extract was then tested with S. commune and P. ostreatus fungi. The most active fraction was isolated using column chromatography with a gradient system, the eluent was methanol:chloroform. Sub-fractions were then tested for fungi to determine the most active sub-fractions, and the most active sub-fractions were then analyzed by 1H NMR. The results showed that the extractive content of pelawan wood was most soluble in chloroform. All extract fractions contain potential as anti-fungal. .The chloroform fraction was very active compared to the other fractions. Isolation of the chloroform fraction by column chromatography obtained 8 sub-fractions. All of these sub-fractions were able to inhibit the growth of S.commune and P.ostreatus with IC(50) = 54.55 - 64.69 mg/L and IC(50) = 54.17 - 64.44 mg/L respectively. PL.3 sub-fraction was the most active among the 8 sub-fractions. The results of 1H NMR analysis on the PL.3 subfraction were shown to be Heptanoic Acid compounds.
Kelarutan Lignin Kayu Cepat Tumbuh dalam Ekstraksi Alkali Deded Sarip Nawawi; Adesna Fatrawana; Wasrin Syafii
Jurnal Ilmu Kehutanan Vol 15 No 1 (2021): Maret
Publisher : Faculty of Forestry Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (546.99 KB) | DOI: 10.22146/jik.v15i1.1512

Abstract

The dissolution of wood lignin in the alkali solution were analyzed for two fast growing species, sengon (Paraserianthes falcataria) dan leda (Eucalyptus deglupta). Wood samples were extracted in 1% sodium hydroxide solution in cold and hot temperatures for 24 and 1 h, respectively. Extractable substances content, permanganate consumption (expressed as assumed lignin content) were analyzed from the filtrates, lignin content and diastereomeric of β-O-4 structure were analyzed from the wood residue after alkali extraction. The extracted substances from both of wood in hot alkali was higher than in cold alkali solution, although the time of cold alkali extraction was much longer that hot alkali extraction. Assumed lignin content in the extract was quite high in both samples which were 34.4-42.9% and 35.5-39.8% including 2,15-2,29% dan 1,04-1,32% of lignin for cold and hot alkali extraction, respectively. The changes in stereo isomeric form, erythro and threo, of β-O-4 structure of lignin in wood residue indicated that partial depolimerization of lignin was takec place during alkali treatment.
Co-Authors Abdul Aziz Darwis Achmad Achmad Achmad Achmad Adesna Fatrawana Adesna Fatrawana Akhiruddin Maddu Akhirudin Maddu Akhirudin Maddu Amril Aman Anak Agung Istri Sri Wiadnyani Ani Suryani Anne Carolina Bambang Prasetya Bambang Prasetya Bambang Prasetya Bintang C. H. Simangunsong Buchari Buchari Buchari Buchari Deded Sarip Nawawi Denny Irawati Desi Melianti Dewi R Agungpriyono E Gumbira Sa, E Gumbira Eka Novriyanti Eka Novriyanti Eko Budi Santoso Eko S Pribadi Elis Nina Herliyana ENDANG SUHENDANG Erdy Santosa Erdy Santosa Evie Nihayah Fabianus Ranta Fahriya Puspita Sari Faizatul FALAH Fathul Yusro Fauzi Febrianto Gunawan Pasaribu Gunawan Pasaribu Gustan Pari Gustan Pari Gustan Pari Gustan Pari Gustan Pari Gustan Pari Gustan Pari Gustan Pari Gustan Pari Gustan Pari Gustan Pari Gustan Pari Gustini Syahbirin Herman Siruru Herman Siruru Hikma Yanti Hiroyuki Yamamoto Husni Y Rosadi, Husni Y I MADE ARTIKA I Nyoman Jaya Wistara IGK Tapa Darma Illah Sailah Imam Wahyudi Indrawan, Imam Wahyudi Irmanida Batubara Irnayuli R. Sitepu Irnayuli R. Sitepu Iskandar Z Siregar Istie Rahayu Izza Firdausi Hadiyanto Jemi, Renhart Juliasman Juliasman Karliati, Tati Khaswar Syamsu Kosei Yamauchi Kurnia Sofyan Kurnia Sofyan Kurnia Sofyan Laela N. Anisah Laela Nur Anisah Latifah K. Darusman Latifah K. Darusman Lucky Risanto M. Daud Maggy T Suhartono Maggy T Suhartono Maman Turjaman Maman Turjaman Maya Ismayati Mody Lempang Mody Lempang Mody Lempang Muflihati Muflihati Muhammad Adly Rahandi Lubis Muhammad Fadli Muhammad Hanafi Nissa Nurfajrin Solihat Norman Razief Azwar Nugraha, Arifin Budiman Nur Adi Saputra Nur Azizah Pudja Mardi utomo Pudja Mardi utomo Purwoko, Agus Rahmi Mauladdini Renhart Jemi Rita K Sari Rita Kartika Sari Romi Irka Putra S Heris Anita Saat Egra Santiyo Wibowo Santiyo Wibowo Santiyo Wibowo Saptadi DARMAWAN Saptadi Darmawan Simon Taka Nuhamara Simon Taka Nuhamara Siruru, Herman Siti Maemunah Siti Sa&#039;diah Siti Sa'diah Soetrisno Hadi Soetrisno Hadi Sri Familasari Suminar A Achmadi Suminar S Achmadi Syamsul Arifin Tohru Mitsunaga Umi Cahyaningsih Widya Fatriasari Widya Fatriasari Widya FATRIASARI Widya FATRIASARI Yanico Hadi Prayogo Yanotama T Laksana Yanti Hikma Yusup AMIN