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All Journal Jurnal Penelitian Saintek EKSAKTA: Journal of Sciences and Data Analysis Jurnal MIPA Jurnal Bios Logos Protobiont: Jurnal Elektronik Biologi Tengkawang : Jurnal Ilmu Kehutanan AL KAUNIYAH Jurnal Produksi Tanaman SEMIRATA 2015 Majalah Obat Tradisional Jurnal Perlindungan Tanaman Indonesia Jurnal Ilmiah Dinamika Rekayasa (DINAREK) BIOMA BIOMA : Jurnal Biologi Makassar Science and Technology Indonesia Jurnal AGROSAINS dan TEKNOLOGI Jurnal Bioteknologi & Biosains Indonesia (JBBI) Jurnal Penelitian Sains Jurnal Biodjati Jurnal Biologi Tropis Indonesian Journal of Chemistry JURNAL PENGABDI Majalah Ilmiah Biologi BIOSFERA: A Scientific Journal Biosaintifika: Journal of Biology & Biology Education Martabe : Jurnal Pengabdian Kepada Masyarakat Jurnal Labora Medika Jurnal Ilmu dan Teknologi Kayu Tropis Floribunda Jurnal Agronomi Tanaman Tropika (JUATIKA) Biologica Samudra ZIRAA'AH MAJALAH ILMIAH PERTANIAN Bioscientist : Jurnal Ilmiah Biologi Jurnal PkM (Pengabdian kepada Masyarakat) Berkala Penelitian Hayati JURNAL BIOLOGI PAPUA JAMAS: Jurnal Abdi Masyarakat Jurnal Bioteknologi & Biosains Indonesia (JBBI) Jurnal Bioteknologi & Biosains Indonesia
Elvi Rusmiyanto Pancaning Wardoyo, Suci Lestari, Mukarlina,
Faculty Of Mathematics And Natural Sciences, University Of Tanjungpura, Jl. Prof. Dr. H. Hadari Nawawi, Pontianak 78124, Indonesia
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Physics Public Health Social Sciences Veterinary

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Journal : BIOMA

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Aktivitas larvasida fraksi metanol dan etil asetat buah lakum (Cayratia trifolia (L.) Domin.) terhadap larva nyamuk Aedes aegypti Diah Wulandari Rousdy; Elvi Rusmiyanto Pancaning Wardoyo; Siti Ifadatin
Bioma : Jurnal Ilmiah Biologi Vol. 10 No. 1: April 2021
Publisher : Universitas PGRI Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26877/bioma.v10i1.5595

Abstract

ABSTRAKAedes aegypti merupakan serangga vektor dari virus Dengue penyebab Demam Berdarah Dengue (DBD). Kandungan senyawa dalam tumbuhan lakum berpotensi sebagai larvasida. Buah lakum dimaserasi dengan pelarut methanol kemudian difraksinasi menggunakan etil asetat. Fraksi diteliti kandungan senyawanya menggunakan analisis fitokimia. Uji larvasida diamati selama 48 jam terdiri dari tujuh konsentrasi berseri yaitu kontrol; 0,04; 0,12; 0,2; 0,6; 1; 3% (b/v). Setiap konsentrasi diulang 3 kali dan setiap ulangan terdiri dari 10 ekor larva nyamuk Ae. aegypti. Data mortalitas dianalisis menggunakan analisis probit untuk menentukan nilai LC50. Fraksi metanol buah lakum  berpotensi sebagai larvasida dengan nilai LC50 6 jam sebesar 1,125%. Fraksi etil asetat  buah lakum  berpotensi sebagai larvasida dengan nilai LC50 6 jam sebesar 1,102%. Buah lakum mengandung senyawa: polifenol, kuinon, flavonoid, alkaloid dan terpenoid. Kata kunci: Aedes aegypti; Cayratia trifolia (L.) Domin; larvasida; LC50  ABSTRACTLarvacidal activity of methanol and ethyl acetate fraction of lakum fruits (Cayratia trifolia (L.) Domin.) against Aedes aegypti larvae. Aedes aegypti is a vector from the Dengue virus which causes Dengue Hemorrhagic Fever (DHF). The compounds of lakum plants has the potential larvicide. The fruit of C. trifolia was macerated with methanol then fractionated using ethyl acetate as a solvent. The fraction was examined for its compound using phytochemical analysis. Larvacide test was observed for 48 hours consisting of seven concentration of 0 (control); 0.04; 0.12; 0.2; 0.6; 1; 3% (w/v). Each concentration was repeated 3 times and each repetition consisted of 10 larvae of Ae. aegypti. Mortality data were analyzed using probit analysis to determine the LC50 of the fraction of methanol and ethyl acetate from lakum fruit. The methanol fraction has the potential larvicide with a six hour LC50 value 1.125%. The ethyl acetate fraction has the potential larvicide with a six hour LC50 value 1.102%. The C. trifolia fruits contains polyphenols, quinones, flavonoids, alkaloids and terpenoids. Keywords: Aedes aegypti; Cayratia trifolia (L.) Domin.; larvacide, LC50
Liver Histopathology of Mice Induced by Paracetamol on Administration of Methanol Extract of Laban Tree Bark (Vitex pubescens Vahl.) Wiwit Anggraini; Diah Wulandari Rousdy; Elvi Rusmiyanto Pancaning Wardoyo
Bioma : Jurnal Ilmiah Biologi Vol 12, No 1: April 2023
Publisher : Universitas PGRI Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26877/bioma.v12i1.11664

Abstract

Paracetamol metabolism takes place in the liver mediated by CYP450 enzymes and generates NAPQI radicals. The NAPQI radical is highly electrophilic to hepatocyte biomolecules and is therefore capable of inducing liver damage. Laban tree bark (V. pubescens) methanol extract is known to contain antioxidant compounds of flavonoids, saponins, and tannins with an IC50 value of 19.83 g/ml. This study aims to determine the optimal dose of extract that can improve the liver microanatomy of mice induced by toxic dose of paracetamol (TDP). This study used 30 male Swiss strain mice with a body weight of 20-30 g. The treatments given consisted of negative control (paracetamol 105 mg kg-1), positive control (vitamin E 46.8 mg kg-1), and laban extract at a dose of 75; 150; 300; 600 mg kg-1 BW. Liver microanatomy parameters measured included hepatocyte diameter (19.50±0.21 µm), sinusoids (4.39±0.23 µm), and central vein (36.84 ± 1.79 µm). Data were analyzed using one-way ANOVA and Duncan's Multiple Range Test further test was then presented in the form of mean ± standard deviation. The results showed that extract at a dose of 600 mg kg-1 had hepatocyte, sinusoid, and central vein diameters that were not significantly different (p>0.05) with vitamin E.
Co-Authors Abraham Sambo Ahmad Yani Nelly Wahyuni Lia Destiarti Ali Djamhuri Andhini Aprilia Anggraini, Wiwit Ara, Chilliany Ari Hepi Ari Hepi Yanti Ari Hepi Yanti Ari Hepi Yanti Ari Widiyantoro Arini Miftahul Jannah Arum Setiawan Arum Setiawan Ary Kusmawati Azkiya, Tiara Catur Wulandari Catur Wulandari Chilliany Ara Cucu Suhery Desy Desy, Desy Devinda Ekarizky Diputri Diah Wulandari Rousdy Diah Wulandari Rousdy Diah Wulandari Rousdy Diah Wulandari Rousdy Diah Wulandari Rousdy Diah Wulandari Rousdy Dian Purnama Sari Dwi Gusmalawati Endah Sayekti Ester Yulinda Evi Noviani Fadhlullah, Hafizh Rizqi Firman Saputra Firman Saputra Fransisko, Satria Fuza Amalia Gusrizal Gusrizal Harlia Harlia Hasan Ashari Oramahi Hildayati, Umi Ibnur Rusi Indri Kusharyanti Irtiawati, Irtiawati Irwan Lovadi Junardi Junardi Kardina, Megawati Kustiati Kustiati Kustiati Laila Hanum Lena Dian Saputri Maryati Maryati Megawati - Mukarlina -, Mukarlina Mukarlina, Mukarlina Nurul Huda Oktavia, Vivi Pancaning Wardoyo Peli, Peli Perdana, Aurendyo Yuscel Rachmad Setijadi, Rachmad Rafdinal Rafdinal Rahmawati Rahmawati Rahmawati Rahmawati Rahmawati, Rahmawati Ratu Safitri Renny Puspita Sari Ribka Sinta Uli Panjaitan Rikhsan Kurniatuhadi, Rikhsan Rina agus setiawati Riyandi Riyandi Riyandi Riyandi Riza Linda Riza Linda Rizki Perdana Putri Rousdy, Diah setiawati, Rina agus Sholihin, Nur Siti Hodijah Siti Ifadatin Siti Ifadatin Siti Khotimah Siti Nur Hasanah, Siti Nur Sulistrioningsih, Sulistrioningsih Sumi, Sumi Tri Rima Setyawati Tsuyoshi Yoshimura Turnip, Masnur Unang Supratman Widya Anggraeni Widya Anggraeni Wiwit Anggraini Yudha Arman Zulfa Zakiah