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All Journal JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Kartika Kimia Jurnal Mandala Pengabdian Masyarakat Current Research on Biosciences and Biotechnology Jurnal Farmasi Sains dan Praktis MOSIRAHA : Jurnal Pengabdian Farmasi Dedikasi: Jurnal Pengabdian Pendidikan dan Teknologi Masyarakat Indonesian Journal of Community Empowerment Jurnal Pengabdian Masyarakat Indonesian Journal of Jamu Dedikasi: Jurnal Pengabdian Pendidikan dan Teknologi Masyarakat Sadewa: Jurnal Pengabdian Masyarakat Journal of Pharmaceutical and Natural Resources
Asniar Pascayantri
Department Of Pharmacy, Faculty Of Pharmacy, Universitas Halu Oleo, Kendari, 93232
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Sosialisasi dan Edukasi Pemanfaatan Tanaman Berkhasiat Obat Dalam Menghadapi Masa Pandemi COVID-19 di Kota Kendari: Socialization and Education Of Effective Medicine Plants In Facing COVID-19 Pandemic in Kendari City Andi Nafisah Tendri Adjeng; Ruslin Ruslin; La Ode Muhammad Fitrawan; Asniar Pascayantri
Jurnal Mandala Pengabdian Masyarakat Vol. 1 No. 2 (2020): Jurnal Mandala Pengabdian Masyarakat
Publisher : Progran Studi Farmasi STIKES Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (545.351 KB) | DOI: 10.35311/jmpm.v1i2.13

Abstract

Coronavirus-19 (COVID) has been declared as world pandemic by WHO. This virus is known to have originated in the city of Wuhan, China since December 2019. The President of the Republic of Indonesia has declared the status of this disease to be an Emergency Response stage in March 2020. In order to quickly handle COVID-19, public understanding of preventive measures for public health COVID-19 is needed in Indonesia, especially in several areas of Kendari City, namely Pondambea and Anduonohu villages. The aim of Halu Oleo University Internal Community Service (PKM) to the community was to help the local government increase public awareness to prevent and fight the Covid-19 virus in the form of utilizing nutritious plants that could increase the body's immune system. The form of community service activities was providing counseling, namely the door to door lecture and discussion method and the distribution of free leaflets and masks, the resulting output is an increase in community understanding and skills in cultivating and utilizing nutritious plants so as to achieve increased peace / public health (general public partners).
IN VITRO CYTOTOXICITY ASSAY OF Petrosia sp. ETHANOL EXTRACT BY USING MTT METHOD OF T47D BREAST CANCER CELL LINE Asniar Pascayantri; Mini Bekti Ningsih; Baru Sadarun; Muhammad Hajrul Malaka; Adryan Fristiohady; Fadhliyah Malik; I Sahidin
Jurnal Farmasi Sains dan Praktis Vol 7 No 3 (2021): Supplementary Issue (The 4th National Pharmacy Conference 2021 Universitas Halu O
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v7i3.6128

Abstract

Breast cancer is increasing as the constraints of side effects, drug-resistant, and high medical costs. Indonesia has a variety of marine biotas that can be explored. The sponge is one of the marines biotas that had potential candidates for anticancer compounds. The secondary metabolites of sponge such as steroids, alkaloids, polyketides, terpenoids, and polyacetylenes have pharmacology effects as anti-inflammation, antineoplastic and cytotoxic activity. The study is aimed to determine the secondary metabolite of Petrosian sp. ethanol extract and the cytotoxic activity at the T47D cell line of breast cancer. The ethanol extract of Petrosian sp. is obtained by maceration using 96% ethanol as a solvent. Extract weight is obtained 274.7 grams with a 2.94% yield of values. Cytotoxicity assay was using MTT methods with IC50 parameters by using software GraphPad prism version 5. Secondary metabolites of Petrosian sp. ethanol extract showing alkaloids, flavonoids, steroids, tannins, and saponins. The possible compound that showed anticancer activity is spinasterol. Cytotoxicity activities of Petrosian sp. ethanol extracts showing IC50 values at 78.13 ppm and IC50 values at 65.88 ppm on positive control. These results proved cytotoxicity activities had moderate cytotoxicity.
SOSIALISASI DAN EDUKASI APOTEKER CILIK DI SD NEGERI 1 SOROPIA Vica Aspadiah; Wahyuni; Asniar Pascayantri; Irvan Anwar; Hasnawati
Mosiraha: Jurnal Pengabdian Farmasi Vol. 1 No. 3 (2023): Edisi Desember 2023
Publisher : Fakultas Farmasi Universitas Halu Oleo

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Abstract

Daerah pesisir merupakan daerah yang cenderung memiliki keterbatasan akses, baik dalam hal sarana dan prasarana ataupun kemajuan pengetahuan khususnya dalam bidang kesehatan. Masyarakat sadar akan pentingnya kesehatan, namun hal tersebut belum diikuti dengan pengetahuan yang benar. Apoteker merupakan salah satu profesi tenaga kesehatan yang keahliannya belum dikenal luas oleh masyarakat. Padahal profesi ini memiliki peran penting dalam memberikan pengetahuan dan pemahaman tentang obat-obatan guna meningkatkan kualitas hidup masyarakat ke arah yang lebih baik. Pengenalan apoteker sejak dini sangat penting sejalan dengan kampanye yang dilaksanakan oleh World Health Organization dalam upaya menjalankan dan menegaskan kegiatan promosi kesehatan yang dilaksanakan di Sekolah-sekolah dasar di Indonesia. Tujuan dari kegiatan pengabdian ini adalah untuk mengedukasi anak-anak di SD Negeri 1 Soropia, Desa Waworaha, Kecamatan Soropia, Kabupaten Konawe agar lebih mengenal profesi Apoteker dan tugasnya serta mengetahui cara penggunaan obat yang baik dan benar sejak dini. Selain itu, agar dapat menumbuhkan minat anak-anak kepada profesi Apoteker dan informasi penggunaan obat yang baik dan benar dapat diterapkan dalam kehidupan mereka sehari-hari. Metode yang digunakan pada kegiatan ini adalah presentasi materi, games, pembagian hadiah, serta pemasangan selempang Apoteker Cilik. Kegiatan sosialisasi apoteker cilik ini dapat memberikan pemahaman materi mengenai Profesi Apoteker dan tugasnya serta cara penggunaan obat yang baik dan benar kepada para peserta yang dibuktikan dengan peningkatan pengetahuan saat tanya jawab setelah sosialisasi.
EDUKASI APOTEKER CILIK PADA SISWA SD NEGERI 3 SOROPIA, KECAMATAN SOROPIA, KABUPATEN KONAWE Ruslin; Wa Ode Sitti Zubaydah; Nita Trinovitasari; Astrid Indahlifiany; Asniar Pascayantri; Rifa'atul Mahmudah; Rahmat Muliadi
Mosiraha: Jurnal Pengabdian Farmasi Vol. 2 No. 1 (2024): Edisi April 2024
Publisher : Fakultas Farmasi Universitas Halu Oleo

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Abstract

Masyarakat mulai sadar akan kesehatan namun belum diikuti dengan pengetahuan yang benar. Upaya dalam pelaksanaan kesehatan pada masyarakat, apoteker memegang peranan penting dalam meningkatkan kualitas hidup masyarakat ke arah yang lebih baik. Pengenalan apoteker sejak dini sangat penting sebagai program pendidikan dan pelayanan kesehatan di tingkat sekolah dasar. Program apoteker cilik di sekolah-sekolah dasar merupakan sebagai bentuk pengenalan dan edukasi mengenai profesi apoteker sehingga dapat menumbuhkan minat generasi muda terhadap profesi apoteker. Tujuan dari kegiatan pengabdian ini adalah untuk memberikan sosialisasi kepada anak-anak usia dini di SDN 3 Soropia, Desa Soropia Kecamatan Soropia, Kabupaten Konawe agar mengetahui profesi apoteker serta tugasnya. Metode yang digunakan pada kegiatan ini adalah presentasi materi, games, pembagian snack, pemberian hadiah, serta pemasangan selempang apoteker cilik. Hasil kegiatan pengabdian ini yaitu anak-anak pesisir SDN 3 Soropia dapat mengetahui sosok profesi Apoteker serta tugasnya. Kesimpulan yang diperoleh dari sosialisasi apoteker cilik yaitu peserta dapat memahami materi mengenai profesi Apoteker serta tugasnya yang dibuktikan dengan peningkatan pengetahuan setelah sosialisasi dan pemahaman anak-anak pesisir SDN 3 Soropia mengenai profesi apoteker.
PENINGKATAN LITERASI MASYARAKAT TENTANG PENGGUNAAN SUNSCREEN SEBAGAI UPAYA PENCEGAHAN PHOTOAGING DI KELURAHAN ANDUONOHU KENDARI Astrid Indalifiany; Asniar Pascayantri; Vica Aspadiah; Rahmat Muliadi; Adibah Nailal Husna; Nabilah Dwijayanti Suleman; Nur Halimah Mutmainah; Sitti Ruhiyat; Tri Wilda Bahir; Atia Fauziah; Sitti Nurjannah; Azzahra Asmaya
MAJU : Indonesian Journal of Community Empowerment Vol. 3 No. 3 (2026): MAJU : Indonesian Journal of Community Empowerment, Mei 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/maju.v3i3.2569

Abstract

High ultraviolet (UV) exposure in tropical regions increases the risk of premature skin aging (photoaging), while public awareness regarding proper sunscreen use remains limited. This community service program aimed to improve community literacy on sunscreen use as an effort to prevent photoaging. The program was conducted in Anduonohu Village, Kendari City through door-to-door education, interactive counseling, sunscreen application demonstrations, leaflet distribution, and evaluation using post-tests and direct discussions. Educational materials included the dangers of UV exposure, selection of SPF and PA, correct sunscreen application techniques, and the importance of reapplication. The results showed an improvement in participants’ understanding and awareness regarding daily sunscreen use. Post-test evaluation indicated that 70% of participants experienced increased knowledge and behavioral changes related to sunscreen use. This activity demonstrates that personal and demonstrative educational approaches are effective in improving community skin health literacy.
IMPLEMENTASI PROGRAM DAGUSIBU MELALUI PENDEKATAN LEAFLET DALAM MENINGKATKAN PENGETAHUAN MASYARAKAT KELURAHAN WATU-WATU TENTANG AKSES DAN PEROLEHAN OBAT YANG TEPAT Asniar Pascayantri; Adryan Fristiohady; Irnawati Irnawati; Asriullah Jabbar; Sabarudin Sabarudin; Hasnawati Hasnawati; Nur Illyin; Astrid Indalifiany; Fadhliyah Malik; Vica Aspadiah; Rahmat Mualiadi; Dian Munasari Solo; La Ode Muhammad Fitrawan; Nasrudin Nasrudin; Ari sartinah; Muhammad Ilyas Y; Mubarak Mubarak
BESIRU : Jurnal Pengabdian Masyarakat Vol. 3 No. 5 (2026): BESIRU : Jurnal Pengabdian Masyarakat, Mei 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v3i5.2570

Abstract

Low drug literacy can lead to drug misuse, irrational self-medication, and the procurement of medicines from unofficial sources. This community service activity aimed to improve the knowledge of Watu-Watu Village residents on proper drug access and acquisition through the DAGUSIBU program, using educational leaflets, discussions, and interactive question-and-answer sessions. Program effectiveness was measured using pre- and post-tests, as well as Likert-scale evaluations. Results showed an increase in community knowledge from 61% to 100%, and the program received a mean evaluation score of 4.83 out of 5. The leaflet-based DAGUSIBU program, combined with active interaction, effectively improved community drug literacy and can serve as a replicable model for community-based pharmaceutical education.
Immunostimulatory Effect of Cayratia trifolia L. Domin on Granulocytes and Natural Killer Cells in Tuberculosis-Induced Rats Muhammad Ilyas Y; Wa Ode Salma; Mubarak Mubarak; Nasrudin Nasrudin; Parawansah Parawansah; Fadhliyah Malik; Asriullah Jabbar; Asniar Pascayantri; Esti Badia; Sernita Sernita; Nirwati Rusli; Lukman La Basy
Jurnal Jamu Indonesia Vol. 11 No. 3 (2026): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v11i3.433

Abstract

Pulmonary tuberculosis (TB) remains a major public health problem in Indonesia and a leading cause of death from infectious diseases, partly because of impaired host immunity. Galing (Cayratia trifolia L. Domin) has been reported to exert immunomodulatory effects in bacterial infections. This study evaluated the immunostimulatory effect of galing leaf and stem extracts on granulocytes and natural killer (NK) cells in a TB-induced rat model. Leaf and stem extracts were administered orally to 28 Wistar rats at doses of 400 and 500 mg/kg body weight for seven days, followed by induction with TB ESAT-6 antigen. Granulocyte counts were measured using a hematology analyzer, whereas NK cells were quantified by ELISA. Galing extract significantly increased granulocyte and NK cell expression compared with the negative control (p<0.05). These findings indicate that galing extract has potential as an immunostimulatory agent in pulmonary TB by enhancing granulocyte and NK cell responses.
EDUKASI DAGUSIBU UNTUK MENINGKATKAN PENGETAHUAN PENGELOLAAN OBAT PADA PASIEN DIABETES MELITUS TIPE 2 Muhammad Arba; Asniar Pascayantri; Asriullah Jabbar; Nasrudin Nasrudin; Al Indra Jaya Tamsa; Eka Safitri; Kadek Ayu Meithasari; Rani Rahmah; Wa Ode Nuryani; Mubarak Mubarak; Wa Ode Mulyana; Muhammad Ilyas Y
MAJU : Indonesian Journal of Community Empowerment Vol. 3 No. 4 (2026): MAJU : Indonesian Journal of Community Empowerment, Juli 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/maju.v3i4.2664

Abstract

Type 2 Diabetes Mellitus is a chronic disease that requires continuous antidiabetic medication use, making adequate knowledge of proper medication management essential for patients. This community service program aimed to improve the knowledge of patients with Type 2 Diabetes Mellitus regarding antidiabetic medication management through education on obtaining, using, storing, and disposing of medicines properly (DAGUSIBU) at the Integrated Non-Communicable Disease Post (Posbindu PTM) of Lepo-Lepo Primary Health Center, Kendari City. The program was conducted through interactive counseling and knowledge assessment using pretest and posttest questionnaires administered to 50 participants. Data were analyzed descriptively and using the Wilcoxon Signed Rank Test. The results showed that the mean knowledge score increased from 47.10 to 91.50 after the educational intervention. Statistical analysis revealed a significant difference between pretest and posttest scores (p<0.001). The normalized gain value of 0.84 indicated a high level of educational effectiveness. This educational program effectively improved participants’ knowledge of antidiabetic medication management and should be implemented continuously to enhance medication literacy among patients with chronic diseases.
Cytotoxic Activity of Chromolaena odorata Ethyl Acetate Fraction and Its Inhibitory Mechanism Through Cell Cycle Modulation Against WiDr Colon Cancer Cells Asniar Pascayantri; Hasnawati Hasnawati; Dian Munasari Solo; Nurramadhani A. Sida; Wa Ode Nurhayati Basri; Sarida Sarida; Aisyah Aisyah; Nurul Azizah Putri Herina; Muhammad Bagas Rahya Arafat
Jurnal Kartika Kimia Vol 9 No 1 (2026): Jurnal Kartika Kimia
Publisher : Department of Chemistry, Faculty of Sciences and Informatics, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkk.v9i1.1057

Abstract

Chromolaena odorata has traditionally been used to treat various diseases such as bacterial and fungal infections, external wounds, stomach ulcers, and vomiting blood. Its anticancer activity has been extensively studied. This study aims to prove the cytotoxic effect of Chromolaena odorata leaves on WiDr colon cancer cells and its inhibitory mechanism through cell cycle modulation. Dried Chromolaena odorata leaves were extracted by maceration using 96% ethanol. They were then triturated with n-hexane and ethyl acetate to obtain n-hexane and ethyl acetate fractions. The ethyl acetate fraction was then screened for phytochemicals using the tube method and tested for cytotoxicity using the MTT assay. The selectivity index (SI) was calculated by comparing the IC50 of WiDr cells to Vero cells. Cell cycle modulation was then observed using flow cytometry. The results showed that the ethyl acetate fraction of Chromolaena odorata leaves contained flavonoids, phenolics, and tannins, and was moderately cytotoxic to WiDr cells with an IC50 of 207.69 µg/mL,, with an SI of 3.5. The ethyl acetate fraction of Chromolaena odorata was able to inhibit the growth of WiDr colon cancer cell division through the G2/M and Sub G1 phases. Thus, it was concluded that the ethyl acetate fraction of Chromolaena odorata has great potential to be developed as a candidate source of colon anticancer agents.
PENINGKATAN KESADARAN MASYARAKAT TENTANG JAMU KEBUGARAN YANG AMAN DAN TERSTANDARISASI SEBAGAI LANGKAH PENCEGAHAN PENYALAHGUNAAN OBAT TRADISIONAL DI KELURAHAN KAMBU Dian Munasari Solo; Asriullah Jabbar; Hasnawati Hasnawati; Fadhliyah Malik; La Ode Muhammad Fitrawan; Nasrudin Nasrudin; Rahmat Muliadi; Elvi Rahmayani; Nurlian Nurlian; Asrumin Asrumin; Asniar Pascayantri; Vica Aspadiah; Mubarak Mubarak; Muhammad Ilyas Y.
BESIRU : Jurnal Pengabdian Masyarakat Vol. 3 No. 6 (2026): BESIRU : Jurnal Pengabdian Masyarakat, Juni 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v3i6.2618

Abstract

Obat tradisional (Jamu) tetap populer di Indonesia karena dianggap aman dan terjangkau. Namun, informasi yang keliru sering kali menyebabkan penggunaan yang tidak tepat serta kurangnya pemahaman mengenai manfaat kesehatan jangka panjang dan standar ilmiah yang berlaku. Di Kelurahan Kambu, pengetahuan masyarakat tentang pemanfaatan jamu yang aman dan terstandarisasi masih sangat terbatas. Program ini bertujuan untuk meningkatkan literasi kesehatan masyarakat dalam upaya pencegahan penyalahgunaan jamu, sekaligus mendorong perilaku konsumsi herbal yang aman dan rasional sesuai dengan standar regulasi yang berlaku. Kegiatan pengabdian kepada masyarakat ini dilaksanakan di Kelurahan Kambu, Kendari, dengan menggunakan pendekatan kunjungan dari rumah ke rumah. Intervensi yang diberikan meliputi ceramah interaktif, diskusi, serta pembagian leaflet informatif kepada 14 responden. Materi edukasi mencakup identifikasi jamu, teknik produksi yang terstandarisasi (CPOTB), serta protokol "CEK KLIK" (Cek Kemasan, Label, Izin edar, dan Kedaluwarsa). Program ini berhasil meningkatkan pemahaman dan keterampilan masyarakat dalam mengolah bahan herbal seperti kunyit, jahe, madu, dan meniran menjadi minuman kebugaran yang aman. Para peserta memperoleh wawasan mengenai takaran, standar keamanan, serta cara memverifikasi registrasi produk melalui kanal resmi BPOM. Integrasi kearifan lokal dengan pendekatan ilmiah terbukti efektif dalam memperkuat kesadaran masyarakat terhadap penggunaan obat tradisional yang aman dan rasional.
Co-Authors ., HALIK Adibah Nailal Husna Adriatman Rasak Adryan Fristiohady Afifah Nur Ramadhani Agus Silfia Susanto Aisah Fitriani Aksan Aishah Handayani Aisyah Aisyah Aisyah Nelpin Mangidi Al Indra Jaya Tamsa Anastasyah Putri Andi Asrianty Angelina Lisar Anwar, Irvan Arba, Muhammad Ari Sartinah Aspadiah, Vica Asriullah Jabbar Asriullah Jabbar Asriullah Jabbar Asrumin Asrumin Astrid Indahlifiany Astrid Indalifiany Astrid Indalifiany Atia Fauziah Azzahra Asmaya Badia, Esti Baru Sadarun Chetrin Priliyani Dhealfa Azzahra Dian Munasari Dian Munasari Solo Dian Munasari Solo Dwi Purnama Sari Eka Safitri Elvania Dwiyanti Poea Elvi Rahmayani Endang Endang Fadhliah Malik Fadhliyah Malik Fadhliyah Malik Fitrawan, La Ode Muhammad Fristiohady, Adryan Hasnawati Hasnawati Indah Nurcahaya Sari Irnawati Irnawati Irvan Irvan Kadek Ayu Meithasari La Ode Muhammad Fitrawan Laila Qodriyah Karimu Loly Subhiaty Idrus Lukman La Basy Lukman La Basy Mallarangeng, Andi Nafisah Tendri Adjeng Manfret Gobai Mayang Sari Mini Bekti Ningsih Mozarivky Salsabilla Javanni Mubarak Mubarak Muhamad Andriawan Muhammad Bagas Rahya Arafat Muhammad Farid Hamuni Muhammad Hajrul Malaka Muhammad Ilyas Y Muhammad Ilyas Y Nabilah Dwijayanti Suleman Nasrudin Nasrudin Nirwati Rusli Nita Trinovitasari Nita Trinovitasari Nur Aviarahma Sihani Nur Halimah Mutmainah Nur Illiyyin Akib Nur Illyin Nurfadillah Sudia Nurhikma Nurhikma Nurlian Nurlian Nurramadhani A. Sida Nursa Yanggun Musria Nurul Azizah Putri Herina Ocha Olyvia Padil Anugrah Parawansah, P Putri Juanti Rachma Malina Rahma Nur Aliza Rahmat Mualiadi RAHMAT MULIADI, RAHMAT Rani Rahmah Refky Caesar Karangan Rifa&#039;atul Mahmudah Rini Apriani Ruslin Ruslin Ruslin Ruslin Ruslin Sabarudin Sabarudin Sahidin Sahidin Sarida Sarida Sernita Silviana Hasanuddin Siti Hayati Sitti Nurjannah Sitti Raodah Nurul Jannah Sitti Ruhiyat Sulsiah Sulsiah Sumi Wally Talitha Nayla Shabira Rivai Theyuci Marchelda Tri Wilda Bahir Tsaqila Aulia Sukma Uswatun Khasanah Vera Yunita Vica Aspadiah Wa Ode Amanah Wa Ode Ifan Mustikawati Wa Ode Mulyana Wa Ode Nurhayati Basri Wa Ode Nuryani Wa Ode Salma Wa Ode Sitti Zubaydah Wahyuni Wahyuni Wanda Januarty Saputri Wianda Puspo Negoro Yuyun Suria