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All Journal Jurnal Ilmu Dasar Journal of Tropical Soils Jurnal Pendidikan Indonesia Jurnal Keterapian Fisik INDONESIAN JOURNAL OF PHARMACY JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA E-Dimas: Jurnal Pengabdian kepada Masyarakat Jurnal Dinamika Pengabdian (JDP) Science and Technology Indonesia AKSIOLOGIYA : Jurnal Pengabdian Kepada Masyarakat BIOEDUSCIENCE Indonesian Journal of Chemistry Jurnal Perikanan Universitas Gadjah Mada JSFK (Jurnal Sains Farmasi & Klinis) Seminar Nasional Lahan Suboptimal Molekul: Jurnal Ilmiah Kimia JFIOnline SELL (Scope of English Language Teaching, Linguistics, and Literature) Journal CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Jurnal Mesin Nusantara SRIWIJAYA JOURNAL OF ENVIRONMENT Jurnal Ilmiah IT CIDA : Diseminasi Teknologi Informasi Pharmaceutical Sciences and Research (PSR) Gaster Journal of Global Pharma Technology Journal of Pharmacy Science and Technology Journal of Prosthetics Orthotics and Science Technology (JPOST) Jurnal Penelitian Sistem Informasi Jurnal Informatika Polinema (JIP) (MJN) SELL (Scope of English Language Teaching, Linguistics, and Literature) Journal Jurnal Terapi Wicara dan Bahasa Jurnal Kefarmasian Indonesia
Dwi Setyawan
Department Of Pharmaceutics, Faculty Of Pharmacy, Universitas Airlangga, Jl. Dharmawangsa Dalam, Surabaya 60286, Indonesia
Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Library & Information Science Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Transportation Veterinary Other

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Nutrient Cycling Index in Relation to Organic Matter and Soil Respiration of Rehabilitated Mine Sites in Kelian, East Kalimantan Setyawan, Dwi; Gilkes, Robert; Tongway, David
JOURNAL OF TROPICAL SOILS Vol. 16 No. 3: September 2011
Publisher : UNIVERSITY OF LAMPUNG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5400/jts.2011.v16i3.219-223

Abstract

Degraded soils at mine sites are often associated with decreased soil fertility.  However, soil nutrient status might be improved through biomass recovery primarily from re-vegetation.  This paper relates nutrient cycling index (NCI) derived from Landscape Function Analysis (LFA) to soil respiration and soil organic matter as a measure of improving soil condition after rehabilitation.  Fieldwork was conducted at Kelian Equatorial Mining, East Kalimantan in June 2001.  Four sites were selected representing rehabilitation work in 1994 (7 year), 2000 (1 year) and 2001 (3 month), and a reference site of undisturbed primary forest.  The NCI value was calculated from scores of basal/canopy cover, litter (abundance, origin and degree of incorporation), cryptogam cover and surface roughness.  Soil respiration was measured using the inverted-box method.  In general, the NCI values increased with age of rehabilitation (12 to 56 %) showing a significant increase compared with the values of reference site (80%).  Soil respiration varied greatly and the values were equally high (200-800 mg CO2 m-2 hr2) across all sites. Tropical soils like those of Kelian might be inherently rich of soil organism as shown by high value of soil respiration.  Nevertheless, the NCI values were not systematically related to soil respiration.  We found that increased organic matter may be used as early sign of functioning soil resources in degraded land.
Pemanfaatan Agen Biologis dalam Pengelolaan Sampah Organik Rumah Tangga di Dusun Bejen Kabupaten Bantul Nuryady, Moh. Mirza; Fauzi, Ahmad; Setyawan, Dwi; Nurwidodo, Nurwidodo; Pratiwi, Ambar; Utami, Inggita; Putra, Ichsan Luqmana Indra; Munir, Misbahul
Aksiologiya: Jurnal Pengabdian Kepada Masyarakat Vol 8 No 4 (2024): November
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/aks.v8i4.11104

Abstract

Sampah organik merupakan hasil dari sisa makan, kayu, ranting, daun, dan kertas, sampah organik mendominasi di Indonesia. Salah satu penghasil sampah organik adalah rumah tangga. Dusun Bejen kabupaten Bantul merupakan penghasil sampah organik tersebut. Dengan adanya Pengabdian Kepada Masyarakat (PKM) menambah pengetahuan dan keterampilan serta kesadaran Warga Dusun Bejen Bantul meningkat dan permasalahan sampah yang belum tertangani di lokasi tersebut dapat terselesaikan. Kegiatan ini dilaksanakan di halaman Musholla Al-Manar, Dusun Bejen pada tanggal 19 Oktober 2021. Pelatihan yang dilakukan berupa pengolahan sampah organik dengan teknik keranjang takakura, eco-enzyme dan ember tumpuk dengan Black Soldier Fly (BSF). Dari hasil pengabdian kepada masyarakat Dusun Bejen terbukti meningkatkan pengetahuan dan keterampilan dalam mengolah sampah organik skala rumah tangga.
Quality of Life Among Diabetic Patients Using Transtibial Prostheses: A Descriptive Study Setyawan, Dwi; Fatati, Muhibbah
Gaster Vol 23 No 2 (2025): AGUSTUS
Publisher : P3M Universitas 'Aisyiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30787/gaster.v23i2.1915

Abstract

Background Diabetes mellitus (DM) is a chronic condition that increases the risk of foot infections, which may lead to gangrene and, in severe cases, lower limb amputation. Transtibial amputation is among the most common procedures, accounting for approximately 85–90% of all limb amputations. The use of a prosthesis is expected to enhance the quality of life (QoL) of post-amputation patients, yet outcomes may vary based on individual factors and causes of amputation. Objective This study aimed to assess the quality of life in patients with transtibial prostheses following amputation due to diabetes mellitus. Methods This descriptive study used observation sheets to evaluate prosthesis usage and the Prosthesis Evaluation Questionnaire (PEQ) to assess quality of life. Participants were transtibial prosthesis users with a history of amputation due to diabetes mellitus. Results Statistical analysis showed a p-value of 0.606 (p > 0.05), indicating no significant difference in quality of life between diabetic amputees and those amputated due to trauma. However, prosthesis use generally contributed to improved mobility and daily functioning. Conclusion While the cause of amputation (diabetes vs. trauma) did not significantly affect overall quality of life, the use of transtibial prostheses supports functional recovery in post-amputation patients. Further research is needed to explore other factors influencing quality of life outcomes in this population.
Pectin Red Dragon Fruit Peel Pectin-Based Microspheres for Oral Quercetin Delivery: Characterization, Stability Study, Digestion Resistance, and Cytotoxicity Against HeLa Cells Kurniawan, Muhammad Fariez; Setyawan, Dwi; Hariyadi, Dewi Melani
Science and Technology Indonesia Vol. 10 No. 4 (2025): October
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2025.10.4.1049-1073

Abstract

This study aims to evaluate the potential of red dragon fruit skin pectin to be used as a polymer compared with commercial pectin in the quercetin microsphere. Microspheres were made using the ionic gelation technique. Ten formulas were created, utilizing pectin from red dragon skin extracted with oxalic acid (OA75), citric acid (CA75), acetic acid (AA75), and commercial pectin at 1% and 1.5% concentrations. A gel permeation chromatography test (GPC) was performed to evaluate pectin’s molecule weight. Parameters were assessed, including yield, moisture content (MC), Carr’s Index, Hausner ratio, swelling index, Fourier Transform Infrared Spectroscopy (FTIR), particle size, polydispersity index (PDI), drug loading (DL), encapsulation efficiency (EE), Scanning Electron Microscope (SEM), in vitro drug release, accelerated stability test at a temperature of 40±2oC and RH 75±5% for 3 months and thermal stability test in the form of DSC and XRD at the same temperature and humidity for 9 months, digestion resistance with incubation in artificial stomach and intestinal solution for 4 hours continued with cytotoxicity test on HeLa cells with MTT Assays. Results of FTIR indicate a strong interaction between quercetin and pectin in forming a stable microsphere structure; SEM showed the spheres morphologically. The kinetics of quercetin release from microspheres was the Korsmeyer-Peppas model. DL and EE had no significant differences for 3 months and no significant changes in the glass transition in the DSC test during testing until month 9. The FF formulation (1.5% AA75) had the highest cytotoxic activity against HeLa cells and a high Selectivity Index.
Microwave-Assisted Synthesis: A Green Chemistry Approach for Drug Cocrystals Synthesis Puspita, Oktavia Eka; Sulistyowaty, Melanny Ika; Salam, Rudy; Setyawan, Dwi
Science and Technology Indonesia Vol. 10 No. 4 (2025): October
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2025.10.4.1130-1147

Abstract

Microwave-assisted synthesis (MAS) presents a promising approach to the formation of pharmaceutical cocrystals, offering notable improvements in solubility, dissolution rate, stability, and bioavailability of active pharmaceutical ingredients (APIs). This review aims to evaluate the potential of MAS as a green and efficient strategy for drug cocrystal synthesis, particularly in comparison to conventional methods such as solvent evaporation, slurry crystallisation, and grinding techniques. A systematic literature review was conducted following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, to ensure a comprehensive selection of relevant studies. The analysis focused on reported synthesis methods, cocrystal formation under microwave exposure, reaction conditions, yields, purity, and scalability outcomes of MAS compared to conventional techniques. This review also highlight current applications, critical synthesis parameters, and challenges such as penetration depth, reaction uniformity, and thermal control. Findings indicate that MAS significantly reduces reaction time, minimizes solvent use, and enhances product purity and yield. Its compatibility with solvent-free or minimal-solvent processes aligns closely with green chemistry principles, making it a sustainable alternative. Furthermore, MAS effectively addresses solubility mismatches and process inefficiencies commonly encountered in traditional methods. The future prospect of MAS lies in its integration with continuous manufacturing, automation, and drug repurposing efforts, which could revolutionize pharmaceutical formulation by accelerating innovation while adhering to environmental and regulatory standards.
Enhancing In Vitro Dissolution of Ferulic Acid Through Co-Crystal Formation Using Malonic Acid and Nicotinamide Co-formers Setyawan, Dwi; Soraya, Yasmin; Ekowati, Juni; Winantari, Agnes Nuniek; Rani, Karina Citra; Kanzaffa, Firly Afnauriza Tedja; Pujiono, Ferry Eko
Science and Technology Indonesia Vol. 10 No. 4 (2025): October
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2025.10.4.1255-1269

Abstract

Ferulic acid is categorized as a Biopharmaceutical Classification System (BCS) class II drug, which exhibits low solubility in water (0.91 mg/mL). The formation of a co-crystal using malonic acid and nicotinamide as co-formers by the microwave irradiation method is an approach to enhance its solubility and dissolution. This study aims to evaluate the effect of co-crystal formation using these two co-formers at a 1:1 molar ratio on the solubility and dissolution of ferulic acid. The result emphasizes the formation of new peaks and peak shifting compared to the pure materials characterized from the Fourier Transform Infrared (FT-IR) spectrum. Moreover, the Differential Scanning Calorimetry (DSC) thermogram exhibits the differences in the co-crystal melting point compared to the pure drug and co-former, indicating the alteration of molecular structure on the crystal lattice of ferulic acid caused by the strong interaction between supramolecular homomer and heteromeric synthon. The formation of a new crystalline phase is also observed from the X-ray Diffraction (XRD) diffractogram, suggesting the formation of a different phase from its co-crystal component. The morphology characterization using Scanning Electron Microscope (SEM) revealed that the ferulic acid crystal habit changes into different forms, which is acclaimed as a co-crystal formation. The results of this study also disclosed that the co-crystal formation of ferulic acid significantly enhances ferulic acid solubility and dissolution characteristics compared to the pure drug and physical mixture (p < 0.05). The enhancement of solubility is 11.85% and 10.39% for ferulic acid–malonic acid and ferulic acid–nicotinamide co-crystal, respectively. Moreover, the dissolution rate of ferulic acid increases 3.50-fold and 3.61-fold from the formation of those co-crystals. Therefore, the formation of ferulic acid–malonic acid as well as ferulic acid–nicotinamide co-crystals in a 1:1 molar ratio by the microwave irradiation method is effective in improving ferulic acid solubility and dissolution.
PERBEDAAN KECEPATAN BERJALAN PADA PENGGUNA TRANSTIBIAL PROSTHESIS TIPE SACH FOOT DAN SINGLE AXIS FOOT: INDONESIA Fatati, Muhibbah; Setyawan, Dwi; Fikria, Laila Hidayatul
Medical Journal of Nusantara Vol. 3 No. 1 (2024): Medical Journal of Nusantara (MJN)
Publisher : Tahta Media Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55080/mjn.v3i1.595

Abstract

Background: Below-knee amputations are the most common amputations in amputation patients. One of the mobility devices that can be used by amputation patients is a prosthesis. The main function of the prosthesis is to help its users be able to walk again and carry out activities normally . The appropriate type of prosthesis is a key factor in rehabilitation. The choice of foot prosthesis type is one of the factors that affect the gait parameter where in the gait parameter there is a walking speed factor. In most cases, the limb wearing the prosthesis does not compensate the amputated limb well, this can affect the speed of walking Method and Subject: This type of research uses analytical observational methods, with a cross-sectional research design. The subjects of this study were users of transtibial prosthesis type SACH foot and single-axis foot. The sample from this study was 16 respondents with purposive sampling techniques. The measuring instruments used in this study were meters and 10 MWT (Meter Walk Test). Results: Based on statistical tests using Mann Whitney, the results were found that there was a difference in walking speed in transtibial prosthesis users of SACH foot and single-axis foot types. Where the p-value (sig) < 0.05 is 0.001 with an effect size (large effect difference) of 0.83 which means it has a high or strong difference effect. Conclusion: there is a difference in walking speed in users of SACH foot and single-axis foot type prosthesis transtibials.
HUBUNGAN JENIS PROSTHETIC FOOT TERHADAP HIPEREKSTENSI DAN KELEMAHAN LIGAMEN PADA PENGGUNA PROSTHESIS TRANSTIBIAL: Indonesian Dwi Setyawan; Muhibbah Fatat
Medical Journal of Nusantara Vol. 3 No. 2 (2024): Medical Journal of Nusantara (MJN)
Publisher : Tahta Media Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55080/mjn.v3i2.895

Abstract

Background: Amputation can be defined as the act of separating part of the body, part or all of an extremity. Currently, lower limb amputations account for 85-90% of all amputations and transtibial amputation is the most frequently performed type of amputation surgery. One of the problems with transtibial amputation is hyperextension and weakness of the ligaments in the knee. Knee hyperextension is a condition that occurs when the knee joint is extended (straightening the knee) excessively, thus putting pressure on the structure of the knee and the back of the knee joint. Ligament weakness in the knee is weakness in the anterior cruciate ligament, posterior cruciate ligament, medial collateral ligament and lateral collateral ligament. Choosing the right prosthesis components can overcome this. One component that plays an important role is the foot component. Methods: This type of research is observational analytic with a cross-sectional design. The research subjects were 17 transtibial prosthesis users. Data analysis in this study used Spearman Rank Test. Results: Based on the Spearman Rank results, the significance result was 0.653 for the type of foot with hyperextension, while for the type of foot with ligament weakness, the significance result was 0.434. Both variables had variable values > 0.05, meaning there was no correlation between foot type and hyperextension and ligament weakness in transtibial prosthesis users. Conclusion: There is no correlation type of foot to hyperextension and ligament weakness. In future research, it is hoped that research can be carried out with a larger number of samples and a more varied type of foot.
PENGARUH PENGGUNAAN CUSTOM INSOLE TERHADAP AGILITY PADA ANAK UMUR 8-12 TAHUN Muhibbah Fatati; Dwi Setyawan
Medical Journal of Nusantara Vol. 4 No. 1 (2025): Medical Journal of Nusantara (MJN)
Publisher : Tahta Media Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55080/mjn.v4i1.1372

Abstract

Background: The foot is a very important part of the limb for walking, and functions as a lever so that the foot is the part that receives the deformity force, so the shape of the sole of the foot has a very important role in carrying out every physical activity. The description above provides an illustration that someone with a flat foot shape has a physical activity ability, namely agility, which is less good compared to someone who has a normal foot shape. Methods and Subjects: The method used in this study is quantitative experimental using a Randomized Controlled Trials (RCT) research design. This study uses a single blinding method where the research subjects do not know what type of insole they are using. The randomized technique in this study uses simple randomization, namely by drawing lots. The sample of this study was 38 respondents, where the control group and the intervention group received the same treatment by being given standard treatment in the form of custom insoles but for the control group they were given regular insoles without medial arch support (MAS). And the intervention group was given insoles with medial arch support (MAS) features. Therefore, in this study, a pre-treatment test was conducted as a basis for determining the level of sample homogeneity, as well as a post-treatment test which was used as data to compare the effectiveness of the intervention between the two groups tested. The measuring instrument used in this study was the Edgren Side Step Test (ESST). Results: The results of the Mann Whitney test showed that there was a difference in the average agility between the intervention group (16.52) and the control group (17.73) with a p value = 0.042 where the p value <0.05.Conclusion: The conclusion of this study is that there is a statistically significant difference in agility in the intervention group and the control group. Where the intervention group has better agility than the control group
The Use of Small Group Discussion on Students' Speaking Skill at MA Al-Hidayah Bangkalan Dwi Setyawan; Hafidz, Moh; Kurdi Wijaya, Moh
SELL (Scope of English Language Teaching, Linguistics, and Literature) Journal Vol. 9 No. 1 (2024): SELL Journal
Publisher : Penerbit STKIP PGRI Bangkalan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31597/sl.v9i1.1014

Abstract

This study explore the use of small group discussion on students’ speaking skill. The issue identified by the researcher during this study is the lack of student participation in learning. As a result, the researcher conducted a study that involved both teachers and students in the learning process. The solution to address this problem was to employ group discussion strategies. Group discussions have proven to be highly effective for students in enhancing their speaking abilities, especially when speaking in public. This learning strategy heavily relies on student engagement, as in this approach, all aspects are decided and executed by the students. In conducting this research, the researcher utilized an approach called Observation and Interview. This research was proven to be effective in improving students' speaking skill
Co-Authors AA Sudharmawan, AA Abdulkadir Rahardjanto, Abdulkadir Achmad Radjaram Agnes Nuniek Winanta Ahmad Zainul AM Mufarrih Amanda Della Yudatama Astuti, Ely Setyo Atok Miftachul Hudha Auzal Halim Bambang Widjaja Bambang Widjaja Bambang Widjaja Bambang Widjaja Betari, Sita Desti Bhisma Murti Bidarinjani, Mouria D Budianta, D Dafa C, Muhammad Dewanthy, Kyrana Sekar Dewi Isadiartuti Dewi Melani Hariyadi Dicky Pratama Dina Ayu Fatmawati Diyah, Nuzul Wahyuning Ekojono Ekojono Erizal Zaini Fadjar Mulya Fajar R, Allak Farid, Saif Aiman Fatati, Muhibbah Fatkur Rhohman, Fatkur Fauzi Ahmad Muda Fauzia, Alfi Nur Fendy Hardian Permana Ferdinand Hukama Taqwa Fery Eko Pujiono, Fery Eko Fikria, Laila Hidayatul Finas Rahmayanti Gatot Sugiarto Gilkes, Robert Hafidz, Moh Handayani, Ning Rahayu Hartanto, Agus Dwi Havidhatul Maulia Herlina Hanum, Herlina HERMANU JOEBAGIO Ichsan Luqmana Indra Putra, Ichsan Luqmana Indra Idha Kusumawati Iin Hindun Ina Sholihah Widiati, Ina Sholihah Indah Sayekti Indah Sayekti, Indah Juni Ekowati Kanzaffa, Firly Afnauriza Tedja Kuamit, Thanawit Kuni Zu’aimah Barikah Kurdi Wijaya, Moh Kurniawan, Muhammad Fariez Lina Winarti Maghzarini, Nessa Regitha Marcellino Rudyanto Maren, A Maria Lucia Ardhani Dwi Lestari Martinus, Ali Melanny Ika Sulistyowaty Misbahul Munir Moh. Mirza Nuryady Muhammad Adi Nugroho Muhammad Setiyawan Muhibbah Fatat Muhibbah Fatati Ningsih, Cica Trimandasari Noorma Rosita Novira Widajanti, Novira Nugroho, Surya Adi Nurhayati Damiri Nuri Nuruddin, Mahrus Naufal Nurwidodo, Nurwidodo Oktavia Eka Puspita, Oktavia Eka Paramita, Diajeng Putri Paserena, Karinda Dwi Prameswari, Putu Pradnya Mimba Pratiwi, Ambar Priatna, S J Pujiono, Ferry Eko Raden Joko Kuncoroningrat Susilo Rani, Karina Citra Refraugati, Irwandi Retno Sari Rohana, Melissa Rosalin Ismayoeng Gusdian Rudy Salam, Rudy Samsun hadi Sari, Ketut Intan Yunika Septiani, Annisa Eka Shofiatul Izzah Al Amaliyah Siammita, Dhea Anansya Siswandono, S. Siswandono, Siswandono Soraya, Yasmin Sukma Adhi Permata Sundani N. Soewandhi, Sundani N. Syafi'ie, Hisyam Tahta Amrillah Tongway, David Tri Agus Siswoyo Utami, Inggita Viddy Agustian Rosidi Wahyu Prihanta Warsito Warsito Widji Soeratri Winantari, Agnes Nuniek Yuanita Windusari Yudi Wicaksono Yudi Wicaksono Yudi Wicaksono Yuli Ainun Najih Zidan, Sabry A. H. Zimy Fianti Ningtyas Zimy Fianti Ningtyas, Zimy Fianti