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All Journal Jurnal Ilmu Dasar Journal of Tropical Soils Jurnal Pendidikan Indonesia Jurnal Keterapian Fisik INDONESIAN JOURNAL OF PHARMACY JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA E-Dimas: Jurnal Pengabdian kepada Masyarakat Jurnal Dinamika Pengabdian (JDP) Science and Technology Indonesia AKSIOLOGIYA : Jurnal Pengabdian Kepada Masyarakat BIOEDUSCIENCE Indonesian Journal of Chemistry Jurnal Perikanan Universitas Gadjah Mada JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Hilirisasi IPTEKS (JHI) Seminar Nasional Lahan Suboptimal PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Molekul: Jurnal Ilmiah Kimia JFIOnline PRIMA: Journal of Community Empowering and Services CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Jurnal Mesin Nusantara SRIWIJAYA JOURNAL OF ENVIRONMENT Jurnal Ilmiah IT CIDA : Diseminasi Teknologi Informasi Pharmaceutical Sciences and Research (PSR) Gaster Journal of Global Pharma Technology Journal of Pharmacy Science and Technology Journal of Prosthetics Orthotics and Science Technology (JPOST) Jurnal Penelitian Sistem Informasi Jurnal Informatika Polinema (JIP) (MJN) Jurnal Terapi Wicara dan Bahasa Jurnal Kefarmasian Indonesia
Dwi Setyawan
Department Of Pharmaceutics, Faculty Of Pharmacy, Universitas Airlangga, Jl. Dharmawangsa Dalam, Surabaya 60286, Indonesia
Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Transportation Veterinary Other

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Pemanfaatan Agen Biologis dalam Pengelolaan Sampah Organik Rumah Tangga di Dusun Bejen Kabupaten Bantul Nuryady, Moh. Mirza; Fauzi, Ahmad; Setyawan, Dwi; Nurwidodo, Nurwidodo; Pratiwi, Ambar; Utami, Inggita; Putra, Ichsan Luqmana Indra; Munir, Misbahul
Aksiologiya: Jurnal Pengabdian Kepada Masyarakat Vol 8 No 4 (2024): November
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/aks.v8i4.11104

Abstract

Sampah organik merupakan hasil dari sisa makan, kayu, ranting, daun, dan kertas, sampah organik mendominasi di Indonesia. Salah satu penghasil sampah organik adalah rumah tangga. Dusun Bejen kabupaten Bantul merupakan penghasil sampah organik tersebut. Dengan adanya Pengabdian Kepada Masyarakat (PKM) menambah pengetahuan dan keterampilan serta kesadaran Warga Dusun Bejen Bantul meningkat dan permasalahan sampah yang belum tertangani di lokasi tersebut dapat terselesaikan. Kegiatan ini dilaksanakan di halaman Musholla Al-Manar, Dusun Bejen pada tanggal 19 Oktober 2021. Pelatihan yang dilakukan berupa pengolahan sampah organik dengan teknik keranjang takakura, eco-enzyme dan ember tumpuk dengan Black Soldier Fly (BSF). Dari hasil pengabdian kepada masyarakat Dusun Bejen terbukti meningkatkan pengetahuan dan keterampilan dalam mengolah sampah organik skala rumah tangga.
Quality of Life Among Diabetic Patients Using Transtibial Prostheses: A Descriptive Study Setyawan, Dwi; Fatati, Muhibbah
Gaster Vol 23 No 2 (2025): AGUSTUS
Publisher : P3M Universitas 'Aisyiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30787/gaster.v23i2.1915

Abstract

Background Diabetes mellitus (DM) is a chronic condition that increases the risk of foot infections, which may lead to gangrene and, in severe cases, lower limb amputation. Transtibial amputation is among the most common procedures, accounting for approximately 85–90% of all limb amputations. The use of a prosthesis is expected to enhance the quality of life (QoL) of post-amputation patients, yet outcomes may vary based on individual factors and causes of amputation. Objective This study aimed to assess the quality of life in patients with transtibial prostheses following amputation due to diabetes mellitus. Methods This descriptive study used observation sheets to evaluate prosthesis usage and the Prosthesis Evaluation Questionnaire (PEQ) to assess quality of life. Participants were transtibial prosthesis users with a history of amputation due to diabetes mellitus. Results Statistical analysis showed a p-value of 0.606 (p > 0.05), indicating no significant difference in quality of life between diabetic amputees and those amputated due to trauma. However, prosthesis use generally contributed to improved mobility and daily functioning. Conclusion While the cause of amputation (diabetes vs. trauma) did not significantly affect overall quality of life, the use of transtibial prostheses supports functional recovery in post-amputation patients. Further research is needed to explore other factors influencing quality of life outcomes in this population.
Pectin Red Dragon Fruit Peel Pectin-Based Microspheres for Oral Quercetin Delivery: Characterization, Stability Study, Digestion Resistance, and Cytotoxicity Against HeLa Cells Kurniawan, Muhammad Fariez; Setyawan, Dwi; Hariyadi, Dewi Melani
Science and Technology Indonesia Vol. 10 No. 4 (2025): October
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2025.10.4.1049-1073

Abstract

This study aims to evaluate the potential of red dragon fruit skin pectin to be used as a polymer compared with commercial pectin in the quercetin microsphere. Microspheres were made using the ionic gelation technique. Ten formulas were created, utilizing pectin from red dragon skin extracted with oxalic acid (OA75), citric acid (CA75), acetic acid (AA75), and commercial pectin at 1% and 1.5% concentrations. A gel permeation chromatography test (GPC) was performed to evaluate pectin’s molecule weight. Parameters were assessed, including yield, moisture content (MC), Carr’s Index, Hausner ratio, swelling index, Fourier Transform Infrared Spectroscopy (FTIR), particle size, polydispersity index (PDI), drug loading (DL), encapsulation efficiency (EE), Scanning Electron Microscope (SEM), in vitro drug release, accelerated stability test at a temperature of 40±2oC and RH 75±5% for 3 months and thermal stability test in the form of DSC and XRD at the same temperature and humidity for 9 months, digestion resistance with incubation in artificial stomach and intestinal solution for 4 hours continued with cytotoxicity test on HeLa cells with MTT Assays. Results of FTIR indicate a strong interaction between quercetin and pectin in forming a stable microsphere structure; SEM showed the spheres morphologically. The kinetics of quercetin release from microspheres was the Korsmeyer-Peppas model. DL and EE had no significant differences for 3 months and no significant changes in the glass transition in the DSC test during testing until month 9. The FF formulation (1.5% AA75) had the highest cytotoxic activity against HeLa cells and a high Selectivity Index.
Microwave-Assisted Synthesis: A Green Chemistry Approach for Drug Cocrystals Synthesis Puspita, Oktavia Eka; Sulistyowaty, Melanny Ika; Salam, Rudy; Setyawan, Dwi
Science and Technology Indonesia Vol. 10 No. 4 (2025): October
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2025.10.4.1130-1147

Abstract

Microwave-assisted synthesis (MAS) presents a promising approach to the formation of pharmaceutical cocrystals, offering notable improvements in solubility, dissolution rate, stability, and bioavailability of active pharmaceutical ingredients (APIs). This review aims to evaluate the potential of MAS as a green and efficient strategy for drug cocrystal synthesis, particularly in comparison to conventional methods such as solvent evaporation, slurry crystallisation, and grinding techniques. A systematic literature review was conducted following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, to ensure a comprehensive selection of relevant studies. The analysis focused on reported synthesis methods, cocrystal formation under microwave exposure, reaction conditions, yields, purity, and scalability outcomes of MAS compared to conventional techniques. This review also highlight current applications, critical synthesis parameters, and challenges such as penetration depth, reaction uniformity, and thermal control. Findings indicate that MAS significantly reduces reaction time, minimizes solvent use, and enhances product purity and yield. Its compatibility with solvent-free or minimal-solvent processes aligns closely with green chemistry principles, making it a sustainable alternative. Furthermore, MAS effectively addresses solubility mismatches and process inefficiencies commonly encountered in traditional methods. The future prospect of MAS lies in its integration with continuous manufacturing, automation, and drug repurposing efforts, which could revolutionize pharmaceutical formulation by accelerating innovation while adhering to environmental and regulatory standards.
Enhancing In Vitro Dissolution of Ferulic Acid Through Co-Crystal Formation Using Malonic Acid and Nicotinamide Co-formers Setyawan, Dwi; Soraya, Yasmin; Ekowati, Juni; Winantari, Agnes Nuniek; Rani, Karina Citra; Kanzaffa, Firly Afnauriza Tedja; Pujiono, Ferry Eko
Science and Technology Indonesia Vol. 10 No. 4 (2025): October
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2025.10.4.1255-1269

Abstract

Ferulic acid is categorized as a Biopharmaceutical Classification System (BCS) class II drug, which exhibits low solubility in water (0.91 mg/mL). The formation of a co-crystal using malonic acid and nicotinamide as co-formers by the microwave irradiation method is an approach to enhance its solubility and dissolution. This study aims to evaluate the effect of co-crystal formation using these two co-formers at a 1:1 molar ratio on the solubility and dissolution of ferulic acid. The result emphasizes the formation of new peaks and peak shifting compared to the pure materials characterized from the Fourier Transform Infrared (FT-IR) spectrum. Moreover, the Differential Scanning Calorimetry (DSC) thermogram exhibits the differences in the co-crystal melting point compared to the pure drug and co-former, indicating the alteration of molecular structure on the crystal lattice of ferulic acid caused by the strong interaction between supramolecular homomer and heteromeric synthon. The formation of a new crystalline phase is also observed from the X-ray Diffraction (XRD) diffractogram, suggesting the formation of a different phase from its co-crystal component. The morphology characterization using Scanning Electron Microscope (SEM) revealed that the ferulic acid crystal habit changes into different forms, which is acclaimed as a co-crystal formation. The results of this study also disclosed that the co-crystal formation of ferulic acid significantly enhances ferulic acid solubility and dissolution characteristics compared to the pure drug and physical mixture (p < 0.05). The enhancement of solubility is 11.85% and 10.39% for ferulic acid–malonic acid and ferulic acid–nicotinamide co-crystal, respectively. Moreover, the dissolution rate of ferulic acid increases 3.50-fold and 3.61-fold from the formation of those co-crystals. Therefore, the formation of ferulic acid–malonic acid as well as ferulic acid–nicotinamide co-crystals in a 1:1 molar ratio by the microwave irradiation method is effective in improving ferulic acid solubility and dissolution.
PERBEDAAN KECEPATAN BERJALAN PADA PENGGUNA TRANSTIBIAL PROSTHESIS TIPE SACH FOOT DAN SINGLE AXIS FOOT: INDONESIA Fatati, Muhibbah; Setyawan, Dwi; Fikria, Laila Hidayatul
Medical Journal of Nusantara Vol. 3 No. 1 (2024): Medical Journal of Nusantara (MJN)
Publisher : Tahta Media Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55080/mjn.v3i1.595

Abstract

Background: Below-knee amputations are the most common amputations in amputation patients. One of the mobility devices that can be used by amputation patients is a prosthesis. The main function of the prosthesis is to help its users be able to walk again and carry out activities normally . The appropriate type of prosthesis is a key factor in rehabilitation. The choice of foot prosthesis type is one of the factors that affect the gait parameter where in the gait parameter there is a walking speed factor. In most cases, the limb wearing the prosthesis does not compensate the amputated limb well, this can affect the speed of walking Method and Subject: This type of research uses analytical observational methods, with a cross-sectional research design. The subjects of this study were users of transtibial prosthesis type SACH foot and single-axis foot. The sample from this study was 16 respondents with purposive sampling techniques. The measuring instruments used in this study were meters and 10 MWT (Meter Walk Test). Results: Based on statistical tests using Mann Whitney, the results were found that there was a difference in walking speed in transtibial prosthesis users of SACH foot and single-axis foot types. Where the p-value (sig) < 0.05 is 0.001 with an effect size (large effect difference) of 0.83 which means it has a high or strong difference effect. Conclusion: there is a difference in walking speed in users of SACH foot and single-axis foot type prosthesis transtibials.
PENGARUH PENGGUNAAN CUSTOM INSOLE TERHADAP AGILITY PADA ANAK UMUR 8-12 TAHUN Muhibbah Fatati; Dwi Setyawan
Medical Journal of Nusantara Vol. 4 No. 1 (2025): Medical Journal of Nusantara (MJN)
Publisher : Tahta Media Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55080/mjn.v4i1.1372

Abstract

Background: The foot is a very important part of the limb for walking, and functions as a lever so that the foot is the part that receives the deformity force, so the shape of the sole of the foot has a very important role in carrying out every physical activity. The description above provides an illustration that someone with a flat foot shape has a physical activity ability, namely agility, which is less good compared to someone who has a normal foot shape. Methods and Subjects: The method used in this study is quantitative experimental using a Randomized Controlled Trials (RCT) research design. This study uses a single blinding method where the research subjects do not know what type of insole they are using. The randomized technique in this study uses simple randomization, namely by drawing lots. The sample of this study was 38 respondents, where the control group and the intervention group received the same treatment by being given standard treatment in the form of custom insoles but for the control group they were given regular insoles without medial arch support (MAS). And the intervention group was given insoles with medial arch support (MAS) features. Therefore, in this study, a pre-treatment test was conducted as a basis for determining the level of sample homogeneity, as well as a post-treatment test which was used as data to compare the effectiveness of the intervention between the two groups tested. The measuring instrument used in this study was the Edgren Side Step Test (ESST). Results: The results of the Mann Whitney test showed that there was a difference in the average agility between the intervention group (16.52) and the control group (17.73) with a p value = 0.042 where the p value <0.05.Conclusion: The conclusion of this study is that there is a statistically significant difference in agility in the intervention group and the control group. Where the intervention group has better agility than the control group
Diversity of Soil Insects in Coal Post Mining Land of PT. Bukit Asam Tbk in Tanjung Enim Paserena, Karinda Dwi; Damiri, Nurhayati; Setyawan, Dwi
Sriwijaya Journal of Environment Vol 9, No 1 (2024): Environment and Suistainable Development
Publisher : Program Pascasarjana Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22135/sje.2024.9.1.11-17

Abstract

Coal mining activities carried out openly can have a negative impact on the environment. One of the environmental damages that occurs is the loss of habitat for soil-level insects. This research was conducted to identify the diversity of soil surface insect species in post-coal mining land of PT. Bukit Asam Tbk Tanjung Enim IUP Banko Barat at various ages of reclamation. Soil surface insect samples were collected using the pitfall trap method which was carried out for 1x24 hours. The results showed that the highest presence of soil surface insect species occurred in aged 6 years with a total of 128 individuals and was dominated by the order Hymenoptera. The species diversity index in post-coal mining land aged 6 years, namely 1.51, is classified as moderate. The lowest presence of soil surface insects occurred in aged 2 years with a total of 24 individuals. The species diversity index in post-coal mining land aged 2 years, namely 0.85, is relatively low. Thus, the research results show that the diversity of surface soil insects is influenced by the age of reclamation. The longer the land is managed, the higher the index of diversity of soil surface insect species in post-coal mining land.
Penguatan Habitus Literasi: Sebuah Cara Pendampingan Tim Literasi Sekolah (TLS) Setyawan, Dwi; Gusdian, Rosalin Ismayoeng
E-Dimas: Jurnal Pengabdian kepada Masyarakat Vol 11, No 3 (2020): E-DIMAS
Publisher : Universitas PGRI Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26877/e-dimas.v11i3.4263

Abstract

Program Gerakan Literasi Sekoalah (GLS) di SDN 1 Sumbersari Kota Malang sudah dilaksanakan. Akan tetapi, selain belum maksimal, belum ada yang mengelola tahapan program dengan baik. Tujuan program pengabdian ini untuk memberikan pendampingan sekolah khususnya pada Tim Literasi Sekolah (TLS) dalam pengelolaan program GLS. Metode pendekatan yang digunakan adalah memberikan sosialisasi, diskusi, workshop, praktik langsung, dan evaluasi. Hasil pendampingan dapat menunjukkan; 1) terbentuknya struktur organisasi TLS, 2) Program literasi yang disusun oleh TLS mampu memberikan informasi dasar keberlangsungan dan keterlaksanaan GLS di tahap pembiasaan, pengembangan, serta pembelajaran. Berdasarkan hasil, dapat disimpulkan bahwa adanya pendampingan TLS program-program leterasi menjadi lebih terstruktur dan terkelola dengan baik.
Literasi Lingkungan Masyarakat Adat dan Masyarakat Perkotaan di Pulau Lombok Bidarinjani, Mouria; Rahardjanto, Abdulkadir; Setyawan, Dwi
BIOEDUSCIENCE Vol 7 No 2 (2023): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/11048

Abstract

Background: The high ability of community environmental literacy can form ideal environmental conditions, but indigenous peoples and urban communities have different understandings of environmental conditions. This study aimed to determine differences in the environmental literacy of indigenous peoples and urban communities on Lombok Island. Methods: The objects of this research are the indigenous people of Bayan Village, North Lombok, and the people of the Dasan Sari Environment, Mataram City, West Lombok: quantitative research methods, quantitative descriptive approaches, and survey research types. Data collection tools are observation, interviews, and questionnaires. Data analysis using SPSS, data analysis techniques by calculating the mean score of the questionnaire. Results: The study obtained a mean environmental literacy value for the indigenous people of Bayan Village at 214.37 and for the Dasan Sari Environmental community at 240.56. The results of the hypothesis testing in this study obtained a significance value greater than 0.05 and t-count < t-table. Conclusions: There was no real difference in environmental literacy between indigenous peoples and urban communities on Lombok Island.
Co-Authors AA Sudharmawan, AA Abdulkadir Rahardjanto, Abdulkadir Achmad Radjaram Adam Pratama Agnes Nuniek Winanta Ahmad Zainul Albertus Aditya Setiawan Almaghrabi, Marey AM Mufarrih Amanda Della Yudatama Anastasia Wheni Indrianingsih Andang Miatmoko Arie Sulistyorini Astuti, Ely Setyo Atok Miftachul Hudha Auzal Halim Bambang Widjaja Bambang Widjaja Bambang Widjaja Bambang Widjaja Betari, Sita Desti Bhisma Murti Bidarinjani, Mouria D Budianta, D Dafa C, Muhammad Dedik Budianta Dewanthy, Kyrana Sekar Dewi Isadiartuti Dewi Melani Hariyadi Dicky Pratama Dina Ayu Fatmawati Dita Savitri Diyah, Nuzul Wahyuning Ekojono Ekojono Erizal Zaini Fadjar Mulya Fajar R, Allak Farid, Saif Aiman Farida Ifadotunnikmah Fatati, Muhibbah Fatkur Rhohman, Fatkur Fauzi Ahmad Muda Fauzia, Alfi Nur Fendy Hardian Permana Ferdinand Hukama Taqwa Ferlinahayati Ferlinahayati Fery Eko Pujiono, Fery Eko Fikria, Laila Hidayatul Finas Rahmayanti Firmansyah Ardian Ramadhani Galih Satrio Putra Gatot Sugiarto Gilkes, Robert Handayani, Ning Rahayu Hartanto, Agus Dwi Havidhatul Maulia Herlina Hanum, Herlina HERMANU JOEBAGIO Ichsan Luqmana Indra Putra, Ichsan Luqmana Indra Idha Kusumawati Iin Hindun Ina Sholihah Widiati, Ina Sholihah Indah Sayekti Indah Sayekti, Indah Juni Ekowati Kanzaffa, Firly Afnauriza Tedja Kawaguchi , Kurnia Kholis Amalia Nofianti Kuamit, Thanawit Kuni Zu’aimah Barikah Kurniawan, Muhammad Fariez Lina Winarti Maghzarini, Nessa Regitha Marcellino Rudyanto Maren, A Maria Lucia Ardhani Dwi Lestari Martinus, Ali Melanny Ika Sulistyowaty Misbahul Munir Moh. Mirza Nuryady Muh. Agus Syamsur Rijal Muhammad Adi Nugroho Muhammad Setiyawan Muhibbah Fatati Ningsih, Cica Trimandasari Noorma Rosita Novira Widajanti, Novira Nugroho, Surya Adi Nurhayati Damiri Nuri Nuruddin, Mahrus Naufal Nurwidodo, Nurwidodo Oktavia Eka Puspita, Oktavia Eka Paramanandana, Abhimata Paramita, Diajeng Putri Paserena, Karinda Dwi Praditapuspa, Ersanda Nurma Prameswari, Putu Pradnya Mimba Pratiwi, Ambar Priatna, S J Pujiono, Ferry Eko Purwitasari, Neny Raden Joko Kuncoroningrat Susilo Rani, Karina Citra Refraugati, Irwandi Resnawati Retno Sari Rohana, Melissa Rosalin Ismayoeng Gusdian Rudy Salam, Rudy Samsun hadi Sari, Ketut Intan Yunika Satria Jaya Priatna, Satria Jaya Seow Lay Jing Septiani, Annisa Eka Shofiatul Izzah Al Amaliyah Siammita, Dhea Anansya Siswandono, S. Siswandono, Siswandono Soraya, Yasmin Sukma Adhi Permata Sulistyowaty, Melanny Sundani N. Soewandhi, Sundani N. Suzana Syafi'ie, Hisyam Tahta Amrillah Tongway, David Tri Agus Siswoyo Tri Widiandani Utami, Inggita Viddy Agustian Rosidi Wahyu Prihanta Warsito . Widji Soeratri Winanda Rizki Febrianti Winantari, Agnes Nuniek Yama Otantia P, Soya Febeauty Yuanita Windusari Yudi Wicaksono Yudi Wicaksono Yudi Wicaksono Yuli Ainun Najih Zidan, Sabry A. H. Zimy Fianti Ningtyas Zimy Fianti Ningtyas, Zimy Fianti