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All Journal Jurnal Teknologi Dan Industri Pangan JURNAL GIZI INDONESIA Jurnal Ilmu keperawatan Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Jurnal Kesehatan Reproduksi Medical Journal of Indonesia UNEJ e-Proceeding Sari Pediatri Paediatrica Indonesiana Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) Jurnal Gizi Klinik Indonesia Jurnal Keperawatan Respati Yogyakarta Basic and Applied Nursing Research Journal Berita Kedokteran Masyarakat Jurnal Farmasi Indonesia Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)

Madarina Julia

Universitas Gadjah Mada

Author-ID : 257273

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Other

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Corticosteroids and obesity in steroid-sensitive and steroid-resistant nephrotic syndrome Nina Lestari; Neti Nurani; Madarina Julia
Paediatrica Indonesiana Vol 55 No 4 (2015): July 2015
Publisher : Indonesian Pediatric Society

Background Children with nephrotic syndrome need high-dose corticosteroids to achieve remission. Studies have estimated a 35-43% risk of obesity in these patients after corticosteroid treatment.Objective To determine the prevalence of obesity in children who received corticosteroids for nephrotic syndrome, and to compare the risk of obesity in children with steroid-sensitive nephrotic syndrome (SSNS) and steroid-resistant nephrotic syndrome (SRNS).Methods We performed a retrospective cohort study in 50 children with SSNS or SRNS who received corticosteroid treatment. Obesity was defined to be a BMI-for-age Z-score above +2.0 SD, according to the WHO Growth Reference 2007. Central obesity was defined to be a waist-to-height ratio > 0.50.Results The overall prevalence of obesity was 22%, with 29% and 14% in the SSNS and SRNS groups, respectively. The overall prevalence of central obesity was 50%, with 54% and 46% in the SSNS and SRNS groups, respectively. The cumulative steroid doses in this study were not significantly different between the SSNS and SRNS groups. There were also no significant differences between groups for risk of obesity (RR 2.53; 95%CI 0.58 to 10.99) or central obesity (RR 1.39; 95%CI 0.45 to 4.25).Conclusion In children with nephrotic syndrome who received corticosteroids, the prevalence of obesity is 22% and of central obesity is 50%. In a comparison of SSNS and SRNS groups, cumulative steroid dose as well as risks of obesity and central obesity do not significantly differ between groups.

The influence of socioeconomic status and birth weight on blood pressure of Indonesian pre-pubertal children Madarina Julia; M M van Weissenburch; HA Delemarrevan de Waal; Achmad Surjono
Paediatrica Indonesiana Vol 47 No 6 (2007): November 2007
Publisher : Indonesian Pediatric Society

Background It has been shown that elevated blood pressure (BP)in childhood contributes to the development of coronary arterydisease, cerebrovascular accidents, heart failure, and renal failurein adults. There is also evidence of some correlations betweenchildhood BP and BP in adulthood. Obesity as well as low birthweight are a risk factors for elevated BP, both in children and inadults. Most epidemiological studies have also shown arelationship between high BP and socioeconomic status (SES).Objective To assess the influence of socioeconomic status andbirth weight on blood pressure of school-aged prepubertal childrenliving in Indonesia.Methods A cross-sectional survey on 2922 school-agedprepubertal children from the rural, poorurban and nonpoor urbancommunities was performed. Data on age, sex, stature, BMI, birthweight, systolic and diastolic BP were collected from all children.Results Overall and within every socioeconomic status group,blood pressures were positively associated with stature and bodymass index (BMI). Children from poor-socioeconomic families,i.e. rural and poor urban, had significantly lower height and BMI,and hence, in the unadjusted analyses, poor socioeconomic statuswas associated with lower systolic and diastolic BP. However, afteradjustment for age, sex, stature and BMI, rural children were foundto have significantly higher systolic BP compared to nonpoor urbanchildren, with regression coefficient (95% CI) of 1.19(0.42 to1.96). Birth weight was not associated with blood pressure inchildhood.Conclusion This study indicated that for a given stature and BMI,poor children had a higher systolic BP

Effect of oral sugar solution for reducing pain in infants underwent diphtheria, pertussis, tetanus (DPT) im- munization: a randomized, double-blind controlled trial Arief Priambodo; Madarina Julia; Djauhar Ismail
Paediatrica Indonesiana Vol 48 No 1 (2008): January 2008
Publisher : Indonesian Pediatric Society

Background Infants are often subjected to painful procedures suchas diphtheria, pertussis, tetanus (DTP) immunization. Despiteits negative effects, pain in infants has not got enough attention.Sweet oral solution has analgesic effect.Objective To determine whether oral sugar solution can reducethe duration of crying in infants who got DTP immunization.Methods This was a randomized, double-blind controlled trialperformed at Growth and Development Clinic of Dr. SardjitoGeneral Hospital and two Primary Health Centers in Yogyakarta.Study subjects were 4-6 month-old infants who got the 3 rd DTPimmunization. Subjects were randomly allocated to receive 2 ml75% oral sugar solution (intervention group) or 2 ml drinkingwater (placebo) just before the immunization. Crying was recordedfrom just before the injection until 3 minutes after.Results Eighty-six subjects were enrolled; 42 subjects receivedsugar solution and 44 subjects received placebo. Sugar solutionreduced the median duration of first cry about 38 seconds or 32%(P=0.03) and reduced the median duration of total crying about35 seconds or 24% (P=0.02).Conclusion Administration of 2 ml 75% oral sugar solution canalleviate pain associated with DTP immunization as shown byreduced duration of crying.

Risk factors of cerebral palsy in the perinatal period Santi Gunarwati; S. Yudha Patria; Madarina Julia
Paediatrica Indonesiana Vol 48 No 3 (2008): May 2008
Publisher : Indonesian Pediatric Society

Background Cerebral palsy is an irreversible yet preventablecondition, thus it is necessary to know the risk factors of thedisease. The potential risk factors that are found in the perinataland neonatal period i.e. asphyxia, sepsis, very low birth weight,premature birth, and neonatal seizure. No available data for therisk factors of cerebral palsy in Indonesia.Objective To identify the perinatal risk factors in cerebral palsy.Methods We performed an age and sex-matched nested case-control study. The case group was children with cerebral palsywho were born at Sardjito Hospital during 1997-2005. The controlgroup was selected from the same population as the case group.Risk factors during the perinatal period consisted of asphyxia,sepsis, very low birth weight, premature birth and neonatal seizure.Logistic regression was used to determine the association betweenrisk factors and cerebral palsy.Results Univariate analysis showed that the following factors wererisk factors for cerebral palsy, i.e., asphyxia (OR 5.6, 95%CI 2.48;12.53); premature birth (OR 4.5; 95%CI 1.55; 13.13); and neona-tal seizure (OR 7.5, 95%CI 3.13; 18.03). On multivariate analysisrisk factors associated with cerebral palsy were asphyxia (aOR6.3, 95%CI 2.42; 16.66) and neonatal seizure (aOR 10.9,95%CI4.03; 29.97).Conclusion Asphyxia and neonatal seizure are significant riskfactors of cerebral palsy in perinatal period

Magnesium intake and insulin resistance in obese adolescent girls Harry Freitag Luglio Muhammad; Emy Huriyati; Rina Susilowati; Madarina Julia
Paediatrica Indonesiana Vol 49 No 4 (2009): July 2009
Publisher : Indonesian Pediatric Society

Background The worldwide increase in the prevalence ofcardiovascular diseases in adulthood is related to obesity inchildren and adolescents. Insulin resistance and hyperinsulinemia observed in obese individuals are the precursors of cardiovascular diseases and type 2 diabetes mellitus. Magnesium, through its action on insulin receptors, is proposed to be an important factor in preventing insulin resistance.Objective The aim of this study was to assess the associationbetween magnesium intake and insulin resistance in obeseadolescent girls.Methods This was a cross-sectional study on obese adolescentgirls in Yogyakarta, Indonesia. Insulin resistance was defined as a HOMA-IR index of3.16 or more. HOMA-IR was calculated usingfasting insulin and plasma glucose levels. Magnesium intake andenergy adjusted magnesium intake were measured using a 24-hour food recall method on 6 non-consecutive days.Results Of 7 8 obese adolescent girls included in our study, 56% of them were found to be insulin resistant. Magnesium intake was only 61 o/o of the recommended daily requirement for adolescent girls. There were no significant associations between magnesium intake and either HOMA-IR or hyperinsulinemia.Conclusion Our study does not find an association betweeninsulin resistance and magnesium intake in obese adolescent girls.

Number of blood pressure measurements needed for screening of hypertension in children and adolescents Madarina Julia
Paediatrica Indonesiana Vol 49 No 4 (2009): July 2009
Publisher : Indonesian Pediatric Society

Background Routine blood pressure assessment is recommended because childhood hypertension is significantly associated with increased risk of cardiovascular disease in adulthood. However, results of blood pressure measurements in children are highly variable, associated with the risk of under or over-diagnosing in hypertension.Objective To assess the optimal number of measurements to screen elevated blood pressures in children and adolescents.Methods This study used two sets of data, i.e. a dataset from 104 obese and non-obese, male and female primary school-children, and a dataset from 79 obese female adolescents. Blood pressure (BP) was measured using standard techniques described by the fourth report of the National High Blood Pressure Education Program (NHBPEP) Working Group on Children and Adolescents. Elevated BP was defined as systolic and diastolic BP at or above the 90th percentile for gender, age, and height.Results BP measurements taken on day-one were significantlyhigher than those taken on day-two and three. This led tohigher prevalence of elevated BP when only one measurementwas performed. Using the average of two measurements in twooccasions detected elevated blood pressure with specificity andpositive predictive value (PPV) ranged from 0. 74 to 1.0 and 0.58to 1.0, respectively.Conclusions It is necessary to measure blood pressure repeatedly to minimize the risk of over-diagnosing in hypertension in children and adolescents. Using the average of three measurements in three visits is recommended, but drawing conclusions based on two measurements in two occasions have yielded sufficiently high specificity.

Influence of socioeconomic status on the association between low weight at birth and stunted growth or overweight in rural and urban Indonesian prepubertal children Madarina Julia; M. M. van Weissenbruch; H. A. Delemarre-van de Waal; Achmad Surjono
Paediatrica Indonesiana Vol 48 No 4 (2008): July 2008
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi48.4.2008.214-9

Background Low birth weight (LBW) has been associated with in-creased risk for both stunted growth andand overweight later in life.Objective To assess relative contribution of LBW on the preva-lence of stunted growth or overweight in rural and urban Indo-nesian children in Indonesia.Methods This is a cross-sectional survey of 2 833 (1125 rural and1708 urban) school-aged prepubertal children. Each child had dataon age, sex, stature, BMI (body mass index) and birth weight.Results Compared to the urban population, the prevalence ofstunted growth was significantly higher in the rural, i.e. 16.3 vs.32.7%, P<O.OOl. However, there was no significant difference iinn the prevalence of LBW in the two communities. While overall,stunted children were more likely to be born with LBW, OR 1.80(95%CI 1.31; 2.47), P<O.OOl. After stratifying data into rural andurban residences, the contribution of LBW on the risk of stuntedgrowth appeared to be only significant in the urban population, OR2.42 (95%CI 1.59; 3.68), P<O.OOl. In the rural, similar proportionsof LBW were found in stunted and not stunted children. Test of in-teraction showed that this difference in OR was significant, the ratioof OR 1.88 (95%CI 1.11; 3.17), P=0.02. We observed no associationbetween LBW and overweight.Conclusions In rural area, LBW is not an important contributorfor stunted growth, while in urbanarea LBW is an important riskfactor for stunted growth. As there is no significant difference inthe prevalence of LBW between the two communities, the dif-ference in the prevalence of stunted growth is more likely to beassociated with different pattern of post-natal growth

Association between obesity and lipid profile in children 10--12 years of age Ruqoyatul Himah; Endy P. Prawirohartono; Madarina Julia
Paediatrica Indonesiana Vol 48 No 5 (2008): September 2008
Publisher : Indonesian Pediatric Society

Background Worldwide prevalence of obesity in children hasbeen increasing. Together with dyslipidemia and hypertension,obesity is associated with higher risk of cardiovascular morbiditylater in life.Objective The aim of this study was to assess associationbetween obesity and occurrence of dyslipidemia in 10-12 yearsold children.Methods We performed a cross sectional study on 53 obese and53 non-obese children matched for age and gender in Yogyakarta.Obesity was defined as body mass index (BMI) at or above the95th percentile of the CDC 2000 reference. The levels of totalcholesterol, LDL-cholesterol, HDL-cholesterol and triglyceridewere measured. Dyslipidemia was defined as increased level oftotal cholesterol, LDL-cholesterol, triglyceride and decreasedlevel of HDL-cholesterol.Results Obese children had higher risk of increased level oftriglyseride, i.e. RR 2.6 (95% CI 1.6 to 4.4), P<O.OOl anddecreased level ofHDL-cholesterol, i.e. RR 17.8 (95%CI 14.0 to20.1), P=0.003. Overall, relative risk for dyslipidemia in obesechildren was 5.2 (95%CI 4.2 to 5.9), P=0.002, higher than innon-obese children.Conclusion Compared to non-obese children, obese children havehigher risk of dyslipidemia, particularly hypertriglyceridemia andhypo-HDL.

Co-Authors A.A. Ketut Agung Cahyawan W Achmad Surjono Adhila Fayasari Agustini Utari Ahmad Husain Asdie Ahmad Husain Asdie Ahmad Husain Asdie Ahmad Husain Asdie Almira Sitasari Aman B Pulungan Andi Imam Arundhana Ari Tri Astuti, Ari Tri Arief Priambodo Astuti, Lucia Mawarti Dwi Attika A. Andarie Basuki, Siswanto Betaditya, Dika Burhan, Fatimah Zahra Cerdasari, Carissa Dewi Astiti Diadra Annisa Dio Biade Djaswadi Dasuki Djauhar Ismail Ekawaty L. Haksari Emy Huriyati Endang Baliarti Endy P. Prawirohartono Endy Paryanto Prawirohartono, Endy Paryanto Eni Harmayani Esti Nurwanti Farida Wahyu Ningtyas Farida Wahyu Ningtyas Farida Wahyu Ningtyias, Farida Wahyu Fitri Haryanti Frida Soesanti Gunawan, I Made Alit H. A. Delemarre-van de Waal HA Delemarrevan de Waal Hamam Hadi Hamam Hadi Handayani Handayani Harry Freitag Luglio Muhammad Helmyati, Siti Hendratini, Julita Hizni, Alina I Made Alit Gunawan I Wayan Bikin ika agustina Indria Laksmi Gamayanti Indria Laksmi Gamayanti Irma Yunawati Joko Susilo Jufrrie, Muhammad Junaidi Junaidi Jurianto Gambir Kandarina, Bernadette Josephine Istiti Khaerul Anwar Kunayarti, Wahyuni Kurnia Febriana Laksono Trisnantoro Lamana, Aspia Legawati Legawati, Legawati Lely Lusmilasari, Lely Lisma Evareny, Mohammad Hakimi, Retna Siwi Padmawati M M van Weissenburch M. M. van Weissenbruch Mohammad Hakimi Muchtar, Mohammad Mursyid, Abidillah Neti Nurani Niken Pritayati Nina Lestari Nisa, Fatma Zuhrotun Noormanto Noormanto, Noormanto Nugroho, Akmad Kharis Nur Afia Amin Nurliyani Nurul Hadi, Nurul Nuryanti Nuryanti Pangesti, Neni Paulinus Deny Krisnanto Purnama, Ni Luh Agustini Putra, Irwansyah R. Dwi Budiningsari Rahayu, Endah Sri Rahmawati, Rahmawati Ramadhaniah, Ramadhaniah Ramli, Nurlaili Retno Sutomo Rianti Puji Lestari Rina Susilowati Riris Andono Ahmad Roni Naning Ronny Martien Ruqoyatul Himah S. Yudha Patria Santi Gunarwati Setya Wandita Shelly Puspa Anggraini Shinta Prawitasari Shoim, Mohammad Siti Nurfadilah H Slamet Rohaedi, Slamet Soeroyo Machfudz, Soeroyo Soi, Beatrix Solly Aryza Sri Mulyati Sri Sugiharti Sri Wahyuni Subardjo, Yovita Puri Sulistyaningrum, Elisa Sunartini Sunartini, Sunartini Susetyowati Tarigan, Noviani Titih Huriah Titih Huriah Toto Sudargo Tunjung Wibowo Tuti Nuraini Tuti Nuraini Winda Irwanti, Winda Winda Nurmayani M Yayah Lakoro Yayi Suryo Prabandari Zulfayeni, Zulfayeni

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