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Adverse events following immunization of mRNA-1273 (Moderna) booster vaccine in clerkship students Hendarto, Hari; Akbar, Femmy Nurul; Nasir, Narila Mutia; Wulandari, Endah; Adlani, Hadianti
International Journal of Public Health Science (IJPHS) Vol 13, No 2: June 2024
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v13i2.23701

Abstract

Two-dose primary vaccine administration was the best strategy to reduce the prevalence and severity of COVID-19. Improved immunity and antibody response to the new variant virus by administering a booster vaccine is needed. Health workers are the main priority for administering the mRNA-1273 (Moderna) booster vaccination in Indonesia. This vaccine has high effectiveness, and safety, however, data and evaluation of adverse events following immunization (AEFI) is required. This study aimed to determine the AEFIs of mRNA-1273 booster vaccination in clinical clerkship students as an early adult age group. The research design was a repeated cross-sectional study using purposive sampling technique. There were 214 subjects who met the requirements. Subject filled out an online questionnaire containing evaluation of AEFIs. The most local AEFIs symptoms were pain at the injection site (79.0%), while the common systemic symptoms were headache, drowsiness, weakness, and fever (37.4%; 26.2%; 9.8%; 9.3%). Most AEFIs were felt within 30 minutes to three days. No respondents required hospitalization, experienced anaphylactic shock, became disabled, or died. The AEFIs did not have a significant relationship with gender, history of allergies, co-morbidities, or history of COVID-19. This information is used as a preventive or educational effort to support implementation vaccine in Indonesia.
Therapeutic Effect of Hijamah (Cupping Therapy) on Lipid Profiles and Apolipoprotein in Hypercholesterolemic Patients Pelawati, Ratna; Widada, Wahyudi; Wulandari, Endah; Mardiyanti, Mardiyanti; Samsiah, Samsiah
Jurnal Keperawatan Soedirman Vol 17 No 2 (2022): Jurnal Keperawatan Soedirman (JKS)
Publisher : Fakultas Ilmu-ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (217.49 KB) | DOI: 10.20884/1.jks.2022.17.2.5692

Abstract

Hijamah or cupping therapy has a therapeutic effect on cholesterol. However, there is still a lack of studies that investigate the potential effect of cupping in managing apolipoprotein B as a proatherogenic agent and apolipoprotein A-1 as an anti-proatherogenic agent. This study aims to explore the effect of cupping therapy on lipid profiles and apolipoproteins in hypercholesterolemic patients. A pre-post experimental design without controls were used. Consecutive sampling was applied to 40 dyslipidemia respondents. The lipid profiles and plasma apolipoproteins A-I (ApoA-I) and apolipoproteins B (ApoB) were measured after the respondents fasted for 12 hours before cupping therapy and 24 hours after cupping therapy. The Wilcoxon sign-rank test was used for the data analysis. The following results were found: average lipid profile (mg/dL) and apolipoprotein (µg/mL) pre vs post cupping: Total Cholesterol (Pre-test vs Post-test) 328 vs 283 (P-value 0.003); TG 238 vs 204 (P- value 0.007); HDL 78.5 vs 85 (P- value 0.000); LDL 195 vs 158 (P- value 0.001); ApoA-1 0.07 vs 0.67 (P-value 0.000); ApoB 2.04 vs 1.82 (P-value 1.000); ApoB/ApoA-1 ratio 30.22 vs 2.93 (P- value 0.000); cholesterol/HDL ratio 4.06 vs 3.08 (P- value 0.332); TG/HDL ratio 3.01 vs 2.83 (P- value 0.104); LDL/ApoB ratio 90.75 vs 83.82 (P- value 0.0837). In conclusion, cupping therapy reduces total cholesterol, TG, LDL, and apoB/ApoA-1 ratio and increases HDL significantly in dyslipidemic patients. Nurses are suggested to include cupping therapy (hijamah) in their intervention for reducing hypercholesterolemia in dyslipidemic patients.
SOSIALISASI APLIKASI TEKNOLOGI PENGOLAHAN KEMBANG GULA BERFLAVOR TEMBAKAU DI DESA DARMAWANGI KECAMATAN TOMO KABUPATEN SUMEDANG Djali, Mohamad; Lembong, Elazmanawati; Wulandari, Endah; Utama, Gemilang Lara
DHARMAKARYA: Jurnal Aplikasi Ipteks untuk Masyarakat Vol 13, No 3 (2024): September : 2024
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/dharmakarya.v13i3.55690

Abstract

Desa Darmawangi merupakan salah satu desa yang berada di Kecamatan Tomo, Sumedang. Desa Darmawangi terkenal sebagai daerah penghasil tembakau. Tembakau merupakan produk pertanian semusim yang tidak termasuk komoditas pangan. Salah satu inovasi kreatif untuk meningkatkan daya guna daun tembakau adalah dijadikan produk olahan pangan yaitu kembang gula berflavor tembakau. Inovasi kreatif ini belum banyak diketahui petani tembakau di Desa Darmawangi sehingga diperlukan sosialisasi potensi daun tembakau untuk pemanfaatannya sebagai bahan olahan pangan khususnya kembang gula. Kegiatan ini dilakukan di Desa Darmawangi Kecamatan Tomo Kabupaten Sumedang. Tujuan dari kegiatan ini adalah untuk melakukan sosialisasi aplikasi teknologi pengolahan kembang gula berflavor tembakau. Metode yang dilakukan pada kegiatan PKM ini adalah kegiatan penyuluhan dan pelaksanaan pre dan post test untuk mengetahui tingkat pemahaman peserta terhadap materi yang diberikan sebelum dan setelah penyuluhan. Hasil dari kegiatan ini adalah meningkatnya pengetahuan masyarakat mengenai teknologi pengolahan kembang gula berflavor tembakau.Darmawangi Village is one of the villages in Tomo District, Sumedang. Darmawangi Village is famous as a tobacco-producing region. Tobacco is a seasonal agricultural product that is not included in food commodities. One of the creative innovations to increase the utility of tobacco leaves is to make processed food products, namely tobacco-flavored confectionery. This creative innovation is not yet widely known by tobacco farmers in Darmawangi Village, so it is necessary to socialize the potential of tobacco leaves for their use as processed food ingredients, especially confectionery. This activity was carried out in Darmawangi Village, Tomo District, Sumedang Regency. The purpose of this activity is to socialize the application of tobacco-flavored confectionery processing technology. The methods used in this PKM activity are counseling activities and the implementation of pre-and post-tests to determine the level of participants' understanding of the material given before and after the counseling. The result of this activity is an increase in public knowledge about tobacco-flavored confectionery processing technology.
Antioxidant and anti-elastase activity of Tampui (Baccaurea macrocarpa) and Ketapong (Terminalia badamia) barks and leaves Ariani, Lusiana; Wulandari, Endah; Desmiaty, Yesi
JURNAL ILMU KEFARMASIAN INDONESIA Vol 22 No 2 (2024): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v22i2.1393

Abstract

Elastase is a protease that is involved in the breakdown of elastin in the dermis. Likewise, free radicals can cause elastin damage. Inhibition of elastase enzyme activity and scavenging of free radicals can prevent premature aging of the skin, especially wrinkles. The current study was to investigate the antioxidant and elastase inhibition properties of the leaves and bark of the Tampui (Baccaurea macrocarpa L.) and Ketapong (Terminalia badamia L.) plants, which may be employed as an anti-aging ingredient in cosmetics and nutraceuticals. B. macrocarpa and T. badamia's leaves and bark were extracted using reflux and 96% ethanol. Anti-elastase was examined using N-succ-(Ala)3-nitroanilide as a substrate, and the DPPH reagent was used to test the antioxidants' activity. Phytochemical screening indicated the presence of flavonoids, quinone, tannins, and steroids. Antioxidant activity of B. macrocarpa leaves (BML), B. macrocarpa bark (BMB), T. badamia leaves (TBL), and T. badamia bark (TBB) had IC50 values were 15.09±0.51; 22.89±1.51; 36.43±1.94; 39.23±1.76 ppm, respectively. The anti-elastase activity of BML, BMB, TBL, and TBB had IC50 values were 48.86±2.29; 52.03±9.54; 44.42±4.53; 40.16±1.32 ppm, respectively. The ethanol extract of B. macrocarpa and T. badamia's leaves and bark exhibits anti-elastase and antioxidant action, proposing that it may be used as an anti-aging agent.
Exploring the Meaning of Ichnography at the Cheng Ho Mosque Endah Wulandari
Jurnal Multidisiplin Sahombu Vol. 5 No. 04 (2025): Jurnal Multidisiplin Sahombu, May - Juny (2025)
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Cheng Hoo Mosque located on Jl. Raya Purbalingga, Selaganggeng Village, Mrebet District, Purbalingga is a mosque building that has a shape resembling a Chinese temple building with a Chinese architectural style. The architecture of the Cheng Hoo Mosque is present to color certain communities dynamically bringing different nuances, because this mosque is an interesting expression to review. Cheng Hoo Mosque in Purbalingga is an interesting research object to be studied related to the meanings contained in its architectural and interior forms. This research object, besides being unique and interesting, also contains aesthetic values displayed through symbols and icons in its architecture and interior. The results of research, analysis, and discussion of the Cheng Hoo Mosque in Purbalingga with an Iconography approach through three stages of analysis, namely pre-iconography, iconography, and iconological interpretation. This mosque shows the artistic motifs in it to represent the aesthetic form with a fantasy style. The theme in the basic concept of Chinese ethnic conflict. The symbolic value contained in the work is to inform that there is a collaboration between China and the archipelago
The Legality of the Provision of Remission to Military Prisoners in Accordance with the Equality Before the Law Principle Wulandari, Endah
Dinasti International Journal of Digital Business Management Vol. 6 No. 3 (2025): Dinasti International Journal of Digital Business Management (April - Mei 2025)
Publisher : Dinasti Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38035/dijdbm.v6i3.4542

Abstract

The Provision of Remissions to Napimil (Military Prisoner) at Lemasmil (Military Penitentiary Institution) is an effort to integrate social reintegration so that soldiers who have the TNI identity are guided by the Soldier's Code of Ethics and / or Officer Code of Ethics, are aware of their mistakes, improve themselves, and do not repeat criminal acts so that they can be accepted and returned to its unit in accordance with the provisions of laws and regulations. Thus, granting remissions to Napimil at Lemasmil is an effort to social reintegration of Napimil, so it needs to be regulated with a clear and straight regulations, in relation to the authority of the TNI Commander in granting Remission requests. The granting of authority to the TNI Commander can only be done if the Military Correctional Law has been issued. Given the importance of structuring the military correctional system, including the provision of remissions for Napimil, it is necessary to support the various competent parties to encourage the Military Correctional Bill to become a priority so that it can be immediately passed along with its derivative regulations.
Analisis Kesulitan Belajar Siswa Dalam Menyelesaikan Masalah Materi Sistem Persamaan Linear Dua Variabel Siswa Kelas VIII SMP 3 Negeri Paron Endah Wulandari; Budi Sasomo; Arum Dwi Rahmawati
Katalis Pendidikan : Jurnal Ilmu Pendidikan dan Matematika Vol. 2 No. 2 (2025): Katalis Pendidikan : Jurnal Ilmu Pendidikan dan Matematika
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/katalis.v2i2.1616

Abstract

The purpose of this study is to find out the difficulties experienced by students in solving mathematical problems, especially in working on or solving problems in the two-variable linear equation system material and to find out the causes of difficulties in the two-variable linear equation system material that has been carried out by grade VIII students. This type of research is qualitative research, namely by making observations, then the researcher gives several questions given to the research subject to work on. The test instrument used in this study is in the form of 2 questions, namely about the material of the two-variable linear equation system that has been validated. The subjects in this study were 19 students in class VIII A who participated in the research process, then the researcher selected 6 students as representatives of the research subjects. The instrument of this study is a written test by giving questions, then interviews. In the results of the research that have been observed along with the results of interviews used to determine the type of difficulty students in solving problems of the two-variable linear equation system, the test results show that students experience difficulties shown by making mistakes in working on the problem. The causes of students' difficulties that often occur are usually lack of concentration when working, difficulties when faced with different forms of problems, forgetting the material that has been taught.
PENGARUH DIGITAL MARKETING DAN MARKETING STRATEGIS TERHADAP BISNIS SUKSES DI MEDIASI LOYALTY PADA UMKM AYAM GEPUK CIKARANG BARU DI KABUPATEN BEKASI Dewi, Putri Shakira; Sofia, Intan Aprilia; Wulandari, Endah; Triyanti, Nurul Hanifa; Septiani, Amelia
Jurnal Review Pendidikan dan Pengajaran Vol. 8 No. 2 (2025): Volume 8 No. 2 Tahun 2025
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jrpp.v8i2.46516

Abstract

Penelitian ini bertujuan untuk menguji pengaruh digital marketing dan marketing strategis terhadap bisnis sukses di mediasi loyalty, pada UMKM Ayam Gepuk Cikarang Baru di Kabupaten Bekasi. Penelitian ini dilatarbelakangi oleh pentingnya adaptasi pemasaran digital dan strategi yang tepat dalam menjaga daya saing UMKM di tengah persaingan kuliner yang kompetitif. Metode yang digunakan adalah kuantitatif melalui survei kuesioner kepada konsumen dengan teknik purposive sampling. Analisis data dilakukan menggunakan Partial Least Squares Structural Equation Modeling (PLS-SEM) melalui software SmartPLS 3.0.Hasil penelitian menunjukkan bahwa digital marketing dan strategi pemasaran berpengaruh signifikan terhadap loyalitas pelanggan. Loyalitas pelanggan juga terbukti memediasi hubungan tersebut terhadap kesuksesan bisnis. Temuan ini menegaskan bahwa membangun loyalitas melalui pendekatan digital dan strategis merupakan kunci dalam mendorong keberhasilan UMKM secara berkelanjutan
Effect of Fermentation on the Phsyco and Functional Properties of Red Sorghum Flour (Sorghum bicolor L.) Lembong, Elazmanawati; Wulandari, Endah; Harlina, Putri Widyanti; Tsalitsu, Syifa
Chimica et Natura Acta Vol 13, No 2 (2025)
Publisher : Departemen Kimia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/cna.v13.n2.57757

Abstract

Modification of red sorghum flour by fermentation method can improve the physical, chemical, and functional properties of the resulting sorghum flour. The purpose of this study was to determine the fermentation time that can affect the physical and functional characteristics of red sorghum flour fermented spontaneous (TSS) and non-spontaneous (TTS). Results indicated that the best treatment was red sorghum flour fermented at 24 hours both spontaneous and non-spontaneous. TSS at 24 hours had a water absorption capacity of 1.04%, oil binding capacity of 1.04%, swelling volume of 7.47%, solubility of 7.57%, initial gelatinization temperature of 76.56oC, peak viscosity of 2855 cP, hot paste viscosity of 2214 cP, breakdown viscosity of 641 cP, cold paste viscosity of 3425 cP, and setback viscosity of 1211 cP. TTS at 24 hours had a water absorption capacity of 1.21%, oil binding capacity of 1.18%, swelling volume of 7.49%, solubility of 8.23%, initial gelatinization temperature of 75.81oC, peak viscosity of 3172 cP, hot paste viscosity of 2600 cP, breakdown viscosity of 572 cP, cold paste viscosity of 5107 cP, and setback viscosity of 2507 cP.
Studi Literatur Model Intervensi terhadap Pasien Prediabetes Wulandari, Endah; Aditama, Lisa
MAHESA : Malahayati Health Student Journal Vol 5, No 8 (2025): Volume 5 Nomor 8 (2025)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v5i8.19133

Abstract

ABSTRACT Prediabetes is a condition characterized by blood sugar levels that are not yet included in the Diabetes Mellitus (DM) category but are too high to be considered normal. Conditions that include prediabetes are Impaired Fasting Glucose (IFG) with blood glucose levels after fasting for around 8-10 hours of 100-125 mg/dl (5.6-6.9 mmol/L) and Impaired Glucose Tolerance (IGT) with Blood sugar levels were 140-199 mg/dl (7.8-11 mmol/L) two hours after being given a load of 75 grams of glucose. The diagnosis of prediabetes can also be made based on the results of an HbA1c examination which shows a figure of 5.7-6.4%. Intervention for prediabetic subjects focuses on maintaining a diet high in fiber and low in fat, physical activity of 75-150 minutes per week, weight loss of 5-7%, stopping smoking and alcohol consumption. The aim of this literature review is to review the current evidence regarding intervention trials aimed at reducing the incidence of Diabetes Mellitus in prediabetic subjects. A literature review shows that lifestyle interventions are effective in preventing and reducing the incidence of DM. Keyword: Interventions Model, Prediabetes, Lifestyle Modifications ABSTRAK Prediabetes adalah suatu kondisi yang ditandai dengan kadar gula darah yang belum termasuk dalam kategori Diabetes Melitus (DM) namun terlalu tinggi untuk dikatakan normal. Kondisi yang termasuk prediabetes yaitu, Impaired Fasting Glucose (IFG) dengan kadar glukosa darah setelah puasa sekitar 8-10 jam sebesar 100-125 mg/dl (5,6-6,9 mmol/L) danImpaired Glucose Tolerance (IGT) dengan kadar gula darah sebesar 140-199 mg/dl (7,8-11 mmol/L) dua jam setelah diberi beban 75 gram glukosa. Diagnosis prediabetes dapat juga ditegakkan berdasarkan hasil pemeriksaan HbA1c yang menunjukkan angka 5,7-6,4%. Intervensi subjek prediabetes berfokus pada mengatur pola makan tinggi serat dan rendah lemak, aktivitas fisik 75-150 menit setiap minggu, penurunan berat badan 5-7%, menghentikan kebiasaan merokok dan konsumsi alkohol. Tujuan dari tinjauan literatur ini adalah meninjau bukti terkini mengenai uji coba intervensi yang bertujuan mengurangi kejadian Diabetes Melitus pada subjek prediabetes. Tinjauan literatur menunjukkan bahwa intervensi lifestyle efektif dalam mencegah dan mengurangi angka kejadian DM. Kata Kunci : Model intervensi, Prediabetes, Modifikasi Gaya Hidup