Article Per Year (5 Year)
p-Index From 2021 - 2026
2.696
P-Index
This Author published in this journals
All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Jurnal Kedokteran Brawijaya Majalah Kesehatan FKUB Medical Laboratory Technology Journal Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Jurnal Biomedika dan Kesehatan Bioscientia Medicina : Journal of Biomedicine and Translational Research MMJ (Mahakam Midwifery Journal) Journal of Issues in Midwifery Jurnal Aisyah : Jurnal Ilmu Kesehatan Bioscientia Medicina : Journal of Biomedicine and Translational Research Malang Respiratory Journal Jurnal Klinik dan Riset Kesehatan Zona Kebidanan : Program Studi Kebidanan Universitas Batam
Eviana Norahmawati
Department Of Anatomic Pathology, Faculty Of Medicine, Brawijaya University, Malang, East Java
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary Other

Published : 30 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Endoglin Expression and the Level of Tgf-Î’ Are Increased In the Placental Tissue and Correlated with Low Fetal Weight in Malaria Infected Mice sasmito, sujarot dwi; Ulfiati, Adilah; Wardana, Ardhian; Nugraheni, Fitriana; Pradiptasari, Nur Fahma; Zulaifa, Zakiyah; Norahmawati, Eviana; Sardjono, Teguh Wahju; Fitri, Loeki Enggar
Journal of Tropical Life Science Vol 5, No 1 (2015)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.5.1.%x

Abstract

Malaria infection during pregnancy can cause accumulation of infected-red blood cells in placental intervillous space and induces placental tissue inflammation and hypoxia. This condition triggers endoglin expression, and release of soluble endoglin which can interfere TGF-β binding to its receptor. The aim of this study was to investigate the correlation between placental endoglin expression and TGF-β level with low fetal weight (LFW) in malaria-infected mice. Nine pregnant mice infected with Plasmodium berghei on the day 9th post mating (malaria infected group) and eight normal pregnant mice (non-infected group) were used in this study. The mice were sacrificed on the day 18th post mating, and all fetal body weights were measured by analytical scale. Enzyme Link Immunosorbent Assay (ELISA) was done to determine the level of placental TGF-β while immunohistochemical staining was performed to examine endoglin expression in placental tissue. The mean of fetal body weights of malaria infected group was significantly lower than non-infected group (p=0,002), while the expression of placental endoglin in malaria infected group was significantly higher than non-infected group (p=0.003). The level of placental TGF-β in malaria infected group was also higher than non-infected group but the difference was not significant (p=0.064). Pearson correlation test showed that there were significant negative correlations between fetal body weights with the level of placental TGF-β (p=0.017, r=-0.568) and the expression of placental endoglin (p=0.002, r=-0.694). Malaria infection in pregnant mice will increase both TGF- β and endoglin in placenta tissue and correlate with low fetal weight.   
Endoglin Expression and the Level of Tgf-Î’ Are Increased In the Placental Tissue and Correlated with Low Fetal Weight in Malaria Infected Mice sujarot dwi sasmito; Adilah Ulfiati; Ardhian Wardana; Fitriana Nugraheni; Nur Fahma Pradiptasari; Zakiyah Zulaifa; Eviana Norahmawati; Teguh Wahju Sardjono; Loeki Enggar Fitri
Journal of Tropical Life Science Vol. 5 No. 1 (2015)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.5.1.%x

Abstract

Malaria infection during pregnancy can cause accumulation of infected-red blood cells in placental intervillous space and induces placental tissue inflammation and hypoxia. This condition triggers endoglin expression, and release of soluble endoglin which can interfere TGF-β binding to its receptor. The aim of this study was to investigate the correlation between placental endoglin expression and TGF-β level with low fetal weight (LFW) in malaria-infected mice. Nine pregnant mice infected with Plasmodium berghei on the day 9th post mating (malaria infected group) and eight normal pregnant mice (non-infected group) were used in this study. The mice were sacrificed on the day 18th post mating, and all fetal body weights were measured by analytical scale. Enzyme Link Immunosorbent Assay (ELISA) was done to determine the level of placental TGF-β while immunohistochemical staining was performed to examine endoglin expression in placental tissue. The mean of fetal body weights of malaria infected group was significantly lower than non-infected group (p=0,002), while the expression of placental endoglin in malaria infected group was significantly higher than non-infected group (p=0.003). The level of placental TGF-β in malaria infected group was also higher than non-infected group but the difference was not significant (p=0.064). Pearson correlation test showed that there were significant negative correlations between fetal body weights with the level of placental TGF-β (p=0.017, r=-0.568) and the expression of placental endoglin (p=0.002, r=-0.694). Malaria infection in pregnant mice will increase both TGF- β and endoglin in placenta tissue and correlate with low fetal weight.   
Co-Authors A.A. Ketut Agung Cahyawan W Adilah Ulfiati Adilah Ulfiati, Adilah Adiwignyo, Dandy Drestanto Agil Dananjaya Aina Angelina Ainun Ganisia Aliesya Patricia Amalia Pradanti Widarso, Amalia Pradanti Ardhian Wardana Ardhian Wardana, Ardhian Aris Rosidah Asmiragani, Syaifullah Dian Sutarini, Ni Luh Gede Didiek Darmadi Ts Dwi Yuni Nur Hidayati Ega Prosfera, Rahma Haryunita Elisa Danik Kurniawati Endah Wijayanti Erawati, Dini Ervina, Rita Fadli, Muhammad Luqman Fitriana Nugraheni Fitriana Nugraheni, Fitriana Frenty Hadiningsih, Eka Hamka Muhammad Nasir Laitupa Harun Al Rasyid Harun Al Rasyid Herpan Syafii Harahap Ihda Dian Kusuma Ineke Permatasari Irmansyah, Istan Irsan, Istan Irmansyah Isharanto, Artono Kenty Wantri Anita, Kenty Wantri Kurnia Penta Seputra Laitupa, Hamka Muhammad Nasir Loeki Enggar Fitri lumban gaol, andy MIFTAHUL JANNAH Miftahul Jannah Mochammad Dalhar Nabila, Astrid Hanan Nanik Setijowati Ni Putu Sri Haryati Noorhamdani Nur Fahma Pradiptasari Nur Fahma Pradiptasari, Nur Fahma Nurdiana Nurdiana Phatama, Krisna Yuarno Pratama, Yudit Alfa` Pratista Adi Krisna, Pratista Adi Pratiwi, Suryanti Dwi Putra, Ngakan Putra, Ngakan Putu Putri Ardela, Mayasari RA Rose Khasana Dewi Rachmad Sarwo Bekti Rahmana, Rahima Azzahra Retnani, Diah Prabawati Retty Ratnawati Ririn Handayani Rose Dewi Satria Pandu Persada Isma Sawitri, Lia Setyawan, Ungky Sri Winarsih Sujarot Dwi Sasmito sujarot dwi sasmito, sujarot dwi SURYANTI Tanti Tri Lestary Tatit Nurseta Teguh Prihanto Teguh Wahju Sardjono Teguh Wahju Sardjono Tinny Endang Endang H Ulfaningtyas, Kiki Wati, Linda Ratna Wiyasa, I Wayan Arsana Yahya Irwanto Yudhanto, Hendy Setyo Zakiyah Zulaifa Zakiyah Zulaifa, Zakiyah