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All Journal Jurnal Kedokteran Syiah Kuala Indonesian Journal of Tropical and Infectious Disease Jurnal Ilmiah Universitas Batanghari Jambi Jurnal Keperawatan Padjadjaran Journal of Maternal and Child Health Manuju : Malahayati Nursing Journal Jurnal Respirologi Indonesia Jurnal Respirasi (JR) JURNAL ILKES (Jurnal Ilmu Kesehatan) Medical and Health Science Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga SURABAYA PHYSICAL MEDICINE AND REHABILITATION JOURNAL Majalah Biomorfologi (Biomorphology Journal) Indian Journal of Forensic Medicine & Toxicology PROFESSIONAL HEALTH JOURNAL Jurnal Abdi Masyarakat Indonesia MEDICINUS Folia Medica Indonesiana

Bakhtiar, Arief

Departemen Pulmonologi Dan Ilmu Kedokteran Respirasi, Fakultas Kedokteran, Universitas Airlangga

Author-ID : 2617773

Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Obstructive Sleep Apneu (OSA), Obesitas Hypoventilation Syndrome (OHS) dan Gagal Napas: [Obstructive Sleep Apnea, Obesity Hypoventilation Syndrome, and Respiratory Failure] Mokhammad Mukhlis; Arief Bakhtiar
Jurnal Respirasi Vol. 1 No. 3 (2015): September 2015
Publisher : Faculty of Medicine Universitas Airlangga

Background: Obstructive sleep apnea (OSA) is a state of the occurrence of upper airway obstruction periodically during sleep that causes breathing to stop intermittently, either complete (apnea) or partial (hipopnea). Obesity hypoventilation syndrome (OHS) is generally defined as a combination of obesity (BMI ≥ 30 kg / mc) with arterial hypercapnia while awake (PaCO2 > 45 mmHg) in the absence of other causes of hypoventilation. Purpose: In order for the pulomonologis can understand the pathogenesis and pathophysiology of OSA and its complications. Literature review: Several studies have been expressed about the link between OSA, OHS with respiratory failure disease. Pathophysiology of OSA, OHS in respiratory failure were difficult to detect, can cause respiratory failure disease management becomes less effective. Conclusion: A good understanding can help with the diagnosis and management of the appropriate conduct to prevent complications of respiratory failure associated with OSA.

Faal Paru Statis: [Static Lung Function] Arief Bakhtiar; Wirya Sastra Amran
Jurnal Respirasi Vol. 2 No. 3 (2016): September 2016
Publisher : Faculty of Medicine Universitas Airlangga

Respiration or breathing is the body’s attempt to meet the needs of O2 in the metabolic process and emit CO2 as a result of intermediary metabolism by lung and respiratory organs together so that the resulting cardiovascular oxygen rich blood. Respiration has three phases: ventilation, diffusion, perfusion. The situation is said to somebody normal lung function if the work process of ventilation, diffusion, perfusion, and the relationship between ventilation to perfusion of the person is in a relaxed state resulted in the partial pressure of arterial blood gas (PaO2 and PaCO2) were normal. Examination of lung function has an important role in assessing a lung function. However, the thing to know that these checks are supporting and quite helpful in making a specific diagnosis. With spirometry examination can be known or determined all the static volume except residual volume and respiratory capacity than the capacity of residual volume that contains components such as total lung capacity and functional residual capacity. Functional residual capacity measured by special methods such as by using the inert gas helium (helium dilution test), N2 washout and bodyplethysmograph. Some static pulmonary function parameters can interpret any kind of disturbance in the lungs. In restrictive disorders in general decreased static lung volumes. While the obstruction interference parameters are quite significant, namely an increase in residual volume (RV), functional residual capacity (FRC) and the ratio of residual volume and total lung capacity (RV/TLC).

Faal Paru Dinamis: [Dynamic Lung Function] Arief Bakhtiar; Renny Irviana Eka Tantri
Jurnal Respirasi Vol. 3 No. 3 (2017): September 2017
Publisher : Faculty of Medicine Universitas Airlangga

Pulmonary function is an examination to measure lung volume function using spirometry. Tests with spirometry to detect abnormalities associated with respiratory distress. Spirometry examination is not only to determine the diagnosis but also to assess the severity of obstruction, restriction, and the effects of treatment. Spirometry examination is a test to measure the volume of a person’s static and dynamic lungs with a spirometer tool. Dynamic lung spirometry consists of Forced vital capacity (FVC), Forced expiratory volume (FEVT), Forced expiratory flow200-1200 / FEF 200-1200, Forced expiratory flow25% -75% / FEF 25% -75%, Peak expiratory flow rate / PEFR, Maximum voluntary ventilation / MVV / MBC, FEV1 / FVC Ratio. Ventilation disorders consist of: restriction and obstruction disorders. Restriction is a disorder of lung development by any cause. In obstruction disorder, it shows a decrease in velocity of expiratory flow and normal vital capacity. FEV values, which are widely used are FEV1 / FVC, abnormal when <80%, FEV1 / FVC ratio <80%. This parameter is very important because the accuracy level for obstruction in the central airway is quite large. In obstructive disorder there is generally a decrease in pulmonary dynamic volume. Significant parameters are FEV 1 / FVC, PEFR, and FEF 25-75. The FEV1 / FVC ratio is important because the accuracy level for obstruction in the central airway is considerable, whereas FEF 25-75 indicates obstruction in the small airway.

Acute Respiratory Distress Syndrome Arief Bakhtiar; Rena Arusita Maranatha
Jurnal Respirasi Vol. 4 No. 2 (2018): Mei 2018
Publisher : Faculty of Medicine Universitas Airlangga

Acute respiratory distress syndrome (ARDS) is a syndrome, a combination of clinical and physiological observations that describe a pathological state. The pathogenesis of ARDS is not completely clear and there is no gold standard for diagnosis. ARDS is characterized by non-cardiogenic pulmonary edema, inflammation of the lungs, hypoxemia, and decreased lung compliance. Acute is defined as a symptom that occurs within one week of a known risk factor. Early clinical manifestations are shortness of breath (dyspneu and tachypneu) which then quickly develop into respiratory failure. ARDS was first described in 1967 by Asbaugh, et al., then the AECC made a definition that was finally refined by Berlin's criteria. Berlin's criteria divided the degree of hypoxemia into 3, namely mild, moderate, and severe, based on the arterial PO2 / FiO2 ratio and the need for PEEP (5 cm H2O or more) which can be given via endotracheal tube or non-invasive ventilation. Sepsis, aspiration of fluid or gastric contents, and multipe transfusion (>15 units/24 hours) are associated with a high risk of ARDS. Cases of ARDS related to pulmonary sepsis, such as pneumonia, inhalational trauma, and pulmonary contusions are as much as 46% or non-pulmonary sepsis as much as 33%. ARDS management includes oxygen therapy and supportive therapy, such as hemodynamics, pharmacotherapy, and nutrition. Further studies are still needed to get a good outcome for ARDS patients.

Relationship Between Anxiety and Asthma Control Among Pregnant Women with Asthma Aenah, Winda; Bakhtiar, Arief; Frety, Endyka Eyre
Journal of Maternal and Child Health Vol. 8 No. 2 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Background: Asthma is a disorder of the airways in the form of chronic inflammation (inflammation). Pregnancy with a history of asthma certainly feels uncomfortable and can interfere with daily activities, this is what will cause an anxiety response. Anxiety in pregnancy with a history of asthma will certainly have an influence on asthma control in pregnant women, so there is a need for research on this case. The purpose of this study was to determine the relationship between anxiety levels and the incidence of asthma control in pregnant women with asthma comorbidities at Airlangga University Hospital, Surabaya. Subjects and Method: This was an analytic observational study with cross sectional design. The sample in this study were pregnant women with comorbid asthma at Airlangga University Hospital who visited from January to March 2022 and sample selection used a purposive sampling method. The dependent variable is the level of asthma control. The independent variable is the level of anxiety. The research instrument used a Hamilton Anxiety Rating Scale (HARS) and Asthma Control Test (ACT) questionnaire. Data were analyzed using the Spearman Correlation test. Results: There was a positive and moderate relationship between anxiety and asthma control in pregnant women with asthma comorbidities. Pregnant women with comorbid asthma who experienced severe anxiety had total control of asthma control, and this result was statistically significant (r= 0.41; p= 0.002). Conclusion: There is a significant relationship between anxiety and the level of asthma control in pregnant women with asthma comorbidities at Airlangga University Hospital. Keywords: pregnancy, anxiety, asthma control. Correspondence: Winda Aenah. Midwifery Program Study, Faculty of Medicine, Universotas Airlangga,Indonesia. Jl. Mayjen Prof.Dr. Moestopo No. 47, Pacar Kembang, Tambaksari, Surabaya 60132, East Java. Email: winda.aenah-2019@fk.unair.ac.id. Mobile: +6285785099130.

Pengaruh Jenis Kelamin Janin dengan Derajat Asma pada Ibu Hamil Trimester II dan III Lia Octaviana; Ivon Diah Wittiarika; Arief Bakhtiar
JURNAL ILKES : Jurnal Ilmu Kesehatan Vol 14 No 1 (2023): Jurnal Ilkes (Jurnal Ilmu Kesehatan)
Publisher : STIKES Karya Husada Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35966/ilkes.v14i1.265

Background: Asthma is still a health problem in the community in almost all countries including Indonesia. The results of a preliminary study conducted by researchers at UNAIR Hospital Surabaya on January 26, 2022, the number of pregnant women with a history of asthma who visited Obstetric Poly, Pulmonary poly, maternity room in January - March 2021 as many as 10 mothers, and there are pregnant women with a history of controlled and uncontrolled asthma with different degrees of asthma and gestational age. Based on these results, it was also obtained that sex of the baby was born with more ratios in female infant as much as 3.79% of the total pregnant women with a history of asthma. The purpose of this study was to analyze the relationship of fetal sex influence with the degree of asthma of pregnant women in the second and third trimesters. Methods: A type of observational analytical research with a Retrospective approach. The total population of pregnant women is 264 with a sample of pregnant women with a history of asthma as many as 31 mothers. Result: Processing research results was carried out which was then carried out statistical tests with the Fisher Exact test obtained a p value of ˂ 0.05. The value is less than the value of α = 1%. Thus, there is a relationship between the Mother's Asthma Degree and the Sex of the Baby they are giving birth to. Furthermore, the Contingency Coefficient test obtained C value of 0.557, so it can be concluded that there is a relationship between the influence of fetal sex and the degree of maternal asthma that has a moderate or sufficient relationship. Conclusion: Based on the results of the analysis using the Fisher exact test, it is known that the sex of the fetus has an influence on the degree of asthma of pregnant women. Most female fetal sex affects the degree of severe asthma, while male fetus tend to have intermittent asthma degrees.

Hasil Konsepsi Ibu Hamil yang Terkonfirmasi Positif COVID-19 Izati Maftuha; Arief Bakhtiar; Dewi Setyowati
Jurnal Ilmiah Universitas Batanghari Jambi Vol 23, No 2 (2023): Juli
Publisher : Universitas Batanghari Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33087/jiubj.v23i2.3562

POGI noted that were 536 pregnant women who were confirmed positive COVID-19 in the past year and 3% of them died. COVID-19 infection in affected pregnant women can affect the mother's conception results. This study aims to describe the results of conception in pregnant women who are confirmed positive for COVID-19. This research is a descriptive observational study with a retrospective approach. The research subjects involved in this study were 31 pregnant women who were positive for COVID-19 and gave birth at Dr. Soetomo Surabaya during January - December 2021. The sampling technique used purposive sampling. Patient data was taken from medical record data. 19 people (61%) tested positive for COVID-19 without symptoms and 12 people with symptoms (39%). 18 people (58%) gave birth by vaginal delivery, 12 people (39%) SC, and 1 people (3%) forceps extraction. There are 3 (10%) mothers who died. Conception results of normal healthy babies were 22 babies (71%), low birth weight 6 babies (4%), IUGR 2 babies (7%), IUFD 1 baby (4%), premature birth 11 people (35%), infant death 2 people (6%), and one baby (3%) who tested positive for COVID-19. Â Most of the results of the conception of pregnant women with confirmed COVID-19 are normal healthy babies.

PREVALENCE OF DIABETES MELLITUS WITH PULMONARY TUBERCULOSIS IN DR. SOETOMO GENERAL ACADEMIC HOSPITAL, SURABAYA, INDONESIA 2016 Heronimus Hansen Kaware; Deby Kusumaningrum; Arief Bakhtiar
Majalah Biomorfologi Vol. 32 No. 1 (2022): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v32i1.2022.18-21

Highlight: 1. The signs and symptoms of patients with pulmonary tuberculosis and those of diabetes mellitus were similar.2. Male, aged 51-75 years old, and working in private sector are characteristics of most of the diabetic patients with pulmonary tuberculosis. Abstract: Background: Diabetes Mellitus is a type of disorder where the patients' blood sugar is above average. Diabetes Mellitus can cause an abundance of comorbidities, from viral infection until metabolic abnormalities. The increased risk of infections is mostly because diabetes mellitus changes how the body works. The changes range from changes in mechanical barriers (humoral immunity) and cellular changes (cellular immunity), the changes of the humoral immunity that can increase the chance of protracting pulmonary tuberculosis. Objective: The purpose of this study was to describe the characteristics of diabetes mellitus in pulmonary tuberculosis in Dr. Soetomo General Academic Hospital, Surabaya, Indonesia from January to December 2016. Materials and Methods: The research method used was an observational study using a cross-sectional design conducted in Central Medical Record for hospitalized patients, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. The diabetes mellitus patients' data collected from the medical records of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia in 2016 were 1,410 and 11 of them were also diagnosed with pulmonary tuberculosis. The final data taken were from 67 out of 115 patients due to the incomplete medical record. Results: According to the data, the most of the diabetic patients with pulmonary tuberculosis were male, age of 51-75 years old, and worked in private sector. Conclusion: There was a significantly higher number of diabetes mellitus withpulmonary tuberculosis patients in older age, males,and private-sector workers. Diabetic patients with pulmonary tuberculosis weremostlymale,aged 51-75 years old, andworked in private sector.

Terapi Montelukast pada Asma Alfian Nur Rosyid; Arief Bakhtiar; Daniel Maranatha; Muhammad Amin
MEDICINUS Vol. 37 No. 1 (2024): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56951/51tkjy13

Asthma is a chronic inflammatory respiratory condition caused by various inflammatory mediators, including those from the arachidonic acid pathway, which serves as a precursor for leukotrienes and prostaglandins. Leukotriene receptor antagonists (LTRAs) have been approved since 1998 as a treatment for asthma. Montelukast is one of the LTRAs that is useful for asthma control, including cases that accompanied by allergic rhinitis. A daily dose of 5-10 mg is recommended for persistent asthma as the preferred controller. LTRAs are not recommended for acute asthma exacerbation due to their relatively slow onset, but they are beneficial in preventing exacerbations. They are also indicated for exercise-induced asthma (EIA), and can be taken 2 hours prior to exercise. Montelukast can be administered as monotherapy or added to LABA-ICS therapy. It is suitable for adults, children, and infants over 1 year of age, preferably taken at night to prevent symptoms in the early morning. Possible side effects include respiratory tract infections, abdominal pain, diarrhea, and neuropsychiatric disorders. Montelukast is considered safe for use during pregnancy and breastfeeding. Physicians should provide comprehensive education for patients regarding medication compliance and the potential risks of side effects. Regular daily use of montelukast is beneficial in preventing acute exacerbations in asthma patients.

Risk Factors of Death in Chronic Obstructive Pulmonary Disease (COPD) Patients at Dr. Soetomo General Academic Hospital, Surabaya, in 2019 Wedhana, Hilmy Indra; Bakhtiar, Arief; Kusuma, Edward; Rosyid, Alfian Nur
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 16 No. 1 (2025): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V16I12025.14-20

Highlights: The highest distribution of chronic obstructive pulmonary disease (COPD) patients’ age and gender was over 60 years old and males. The highest distribution of COPD patients’ comorbidity was infection, with pneumonia being the most common infection. Abstract Introduction: The distribution of death and risk factors in chronic obstructive pulmonary disease (COPD) patients varies according to disease severity. This study aimed to determine the risk factors of mortality in COPD patients. Methods: This was a retrospective descriptive study with a total sampling method using inclusion and exclusion criteria. Data collection was performed on patients' medical records throughout 2019. The inclusion criteria for this study sample were patients diagnosed with COPD who died in 2019, aged over 25 years old (adults), both male and female. The exclusion criteria were COPD patients with incomplete medical record data. Results: The total number of samples obtained and included in this study was 31 COPD patients (n=31). The characteristics of the patients showed a predominance of males over females, with a ratio of 9:1. Seventeen samples (58.0%) out of 31 were patients aged >66 years old. Comorbidities accounted for 96.8% of the study population. The most prevalent comorbidity was infection (77.41%), with pneumonia accounting for 38.7% of all deaths. Eighteen patients (58.1%) reported having two or more comorbidities, whilst 28 patients (90.3%) scored 0-7 on the Modified Sequential Organ Failure Assessment (mSOFA) when admitted to the hospital. Conclusion: This study found that the group of patients with the mSOFA score of 0-7 with the characteristics of being aged >60 years old, males, and having pneumonia infection had the highest mortality rate among other COPD patients who died.

Co-Authors Adi, Ginanjar Sasmito Adyan Donastin Aenah, Winda Alfian Nurfaizi Andis Putri Nawangasri Anggraeni, Zuhrotul Eka Yulis Ardyan, Raghda Amanda Asmarawati, Tri Pudy Aulia Rahman, Nuha Ayesie Natasha Zulka Bambang Soeprijanto Budi Sutikno Budiono Budiono Dahlia Damayanti Deby Kusumaningrum Dewi Setyowati Dewi Setyowati Donastin, Adyan Effendi, Wiwin Is Ely Rahmatika Nugrahani Ely Rahmatika Nugrahani, Ely Rahmatika Esti Maulidya Suryaningrum Farah Fatma Wati Firdausi Rafidah, Salsabila Frety, Endyka Eyre Ginanjar Sasmito Adi Hakim, Arief Rakhman Harianto Notopuro Heronimus Hansen Kaware Humairah, Ira Indiastuti, Danti Nur Indrawanto, Dwi Wahyu Indri Safitri Indri Safitri, Indri Irmi Syafa'ah Isnin Anang Marhana Ivon Diah Wittiarika Izati Maftuha Khaerunnisa, Siti Kurniawati, Ninuk Dian Kusmiati, Tutik Kusnanto Kusnanto Kusuma, Edward Putra Lia Octaviana Lukitasari, Lina Maranatha, Daniel Maulaningtyas, Hamidia Mochamad Yusuf Alsagaff Mokhammad Mukhlis Muhammad Amin Muhammad Amin Muhammad Muhajir Muhammad Raihan Habibi Muhammad Sajidin Najich Riza Firmansyah, Achmad Ni Made Mertaniasih Nur, Akbar Permatasari, Ariani Prabowo, Gwenny Ichsan Putri Mega Juwita Putri, Mayandra Alif Anggita Qurnianingsih, Ema Rahmawati Hariputri, Wulan Ramadhani, Nabila Putri Himawati Rena Arusita Maranatha Renny Irviana Eka Tantri Resti Yudhawati Retno Asih Setyoningrum Retno Handajani Rista Elva Riani Rosyid, Alfian Nur Sari, Gadis Meinar Satriyo Dwi Suryantoro Semedi, Bambang Pudjo Setiawati, Rosy Siti Khaerunnisa Soedarsono Soedarsono SOETJIPTO . Sofia Al Farizi Susi Wahyuning Asih Susi Wahyuning Asih, Susi Wahyuning Suwandito Suwandito Suwandito, Suwandito Syafa'ah, Irmi Syafa’ah, Irmi Tanoto, Julius Wardhana, Manggala Pasca Wedhana, Hilmy Indra Wennas, Vindy Vanessa Wirya Sastra Amran Wungu, Citrawati Dyah Kencono Zuhrotul Eka Yulis Anggraeni Zulka, Ayesie Natasha

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