Heri Setiyo Bekti
Department Of Medical Laboratory Technology, Politeknik Kesehatan Kemenkes Denpasar, Denpasar, Bali, Indonesia And Center Of Excelence In Science And Technology, Polytechnic Of Health Denpasar, Bali, Indonesia

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Journal : Muhammadiyah Medical Journal

The Effectiveness of Green Grape Extract (Vitis vinifera) on Decreasing White Rat (Rattus novergicus) Triglycerides Levels Arwati, Ketut Lilik; Dewi, Ni Nyoman Astika; Bekti, Heri Setiyo; Dewi, Ni Wayan Rika Kumara; Saransi, Andi Udin
Muhammadiyah Medical Journal Vol 3, No 1 (2022): Muhammadiyah Medical Journal (MMJ)
Publisher : Faculty of Medicine and Health Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/mmj.3.1.1-9

Abstract

Background: Grapes (Vitis vinifera) are a source of antioxidants with high content of polyphenols and anthocyanins. Grape skin is rich in flavonoids. Anthocyanins and flavonoids have the effect of lowering blood triglyceride levels. Purposes: This study aimed to determine the effect of using green grape extract (GGE) in lowering triglyceride levels in the blood. Methods: Five groups of white male rats (Rattus novergicus) were divided into a negative control group (KN), positive control (KP), rats with a GGE dose of 100 mg/200g BW as P1, rats with a GGE dose of 250mg/200g BW as P2, and rats with GGE dose of 500 mg/200g BW as P3. Each group was given a hypercholesterolemic diet for five weeks. Groups P1, P2, and P3 were given GGE according to their respective doses for 14 days, then measured triglyceride levels in the blood. Results: The results showed that GGE 500mg/200g BW significantly reduced triglyceride levels in all treated mice. Conclusion: These results indicate that GGE has a great potential to treat dyslipidemia by lowering triglyceride levels in the blood.
A Patient with Suspect Chronic Myeloid Leukemia: A Case Report Dharmawaiswari, Anak Agung Ayu Ratih; Tedja, I Gusti Ayu Wiradari; Prianggandanni, Made Ayu Vita; Dharmawati, I Gusti Agung Ayu; Bekti, Heri Setiyo
Muhammadiyah Medical Journal Vol 5, No 2 (2024): Muhammadiyah Medical Journal (MMJ)
Publisher : Faculty of Medicine and Health Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/mmj.5.2.116-121

Abstract

Chronic myeloid leukemia (CML) is a type of cancer that starts in the blood-forming cells of the bone marrow. In contrast to other types of leukemia, chronic myeloid leukemia (CML) progresses slowly. This report covers a 52-year-old male patient who came to the emergency room at Wangaya Regional Hospital with weakness, nausea, and pallor. His weight had drastically decreased over the last few months. The clinical condition of the patient was that both eyes appeared anemic, and the abdominal examination revealed hepatomegaly. Complete blood count examination results showed the following results: leukocytes 222.73x103/µl, hemoglobin 7.3 g/dL, platelets 679x103/µl, neutrophil 87.5%, neutrophil/lymphocyte ratio 16.66%. The results of peripheral blood smear analysis showed that hyperleukocytosis, with the maturation stage of myelocyte cells with a percentage of myeloblasts 6%, promyelocytes 7%, myelocytes 6%, metamyelocytes 8%, neutrophils 10%, neutrophil segments 60%, other cells 3%. These examination results suggest chronic myeloid leukemia. However, to confirm the diagnosis, the BCR-ABL fusion protein must be expressed, which can be used to identify the presence or absence of the Philadelphia chromosome in patients diagnosed with chronic myeloid leukemia (CML).
Uric Acid Levels in Pregnant Women Haribaik, Anastaysia Annisa; Bekti, Heri Setiyo; Posmaningsih, Dewa Ayu Agustini
Muhammadiyah Medical Journal Vol 3, No 2 (2022): Muhammadiyah Medical Journal (MMJ)
Publisher : Faculty of Medicine and Health Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/mmj.3.2.53-59

Abstract

Background: Preeclampsia in pregnant women can be detected by measuring uric acid levels in the blood. This can occur due to changes in the hemodynamic system and decreased glomerular filtration rate during pregnancy. Purposes: This study aims to determine the description of uric acid levels in pregnant women at Community Health Centers I, South Denpasar. Methods: This study uses a descriptive observational method from April to May 2022, with 31 respondents obtained by non-probability sampling technique. Uric acid levels were measured by the Point of Care Testing (POCT) method. Results: The results showed 23 pregnant women (74.2%) with normal uric acid levels and eight pregnant women (25.8%) with high uric acid levels. Conclusion: High uric acid levels are most suffered by pregnant women aged 30 years (16.1%), most commonly found in the third trimester of pregnancy (16.1%), most pregnant women with a body mass index (BMI) more and obesity (9.7%), and pregnant women with normal blood pressure (22.6%).
Primers application with the Tso31 gene target in the molecular identification of Taenia solium Habibah, Nur; Bekti, Heri Setiyo; Kumara Dewi, Ni Wayan Rika; Rinawati, Luh Putu; Burhannuddin, Burhannuddin; Rakhmawati, Aprilia
Muhammadiyah Medical Journal Vol 2, No 1 (2021): Muhammadiyah Medical Journal (MMJ)
Publisher : Faculty of Medicine and Health Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (271.651 KB) | DOI: 10.24853/mmj.2.1.35-40

Abstract

Background: taeniasis is a zoonotic disease caused by Taenia spp. Human taeniasis caused by Taenia solium can be acquired after consumption of raw insufficiently cooked infected pork meat. Pigs are intermediate host for T.solium. Pigs acquired this infection by eating human feces that contained T.solium eggs. Pigs infected with T.solium can be transmitted to humans. Purposes: identification of T.solium in pig is important because it is indicator of T.solium transmission. Microscopic examination of T.solium eggs is considered less effective and efficient so that many other methods are developed for T.solium detection such as molecular and immunology. Method: This method used specific primer which can detect the Tso31 gene in T.solium. Tso31 gene is one of the most promising antigens to differentiate T.solium from T.saginata. Pig feces samples were taken by random sampling technique from 7 pig farms in Denpasar. Result: from the 30 samples, we found one sample that which gave a single amplification product of 234 bp. This indicates that the pig farms in Denpasar have been infected with T.solium. Conclusion: it is necessary to do meat inspection properly in the market as well as health education about the dangers and impacts of T.solium infection in the community.
Co-Authors Ade Dharmawan Agus Sri Lestari Amany, Hana Amirah ANDI UDIN SARANSI Anniwati, Leonita Aprilia Rakhmawati Aprilia Rakhmawati Aprilia Rakhmawati Aprilia Rakhmawati Arjani, Ida Ayu Made Sri Artawa, I Made Budi Arwati, Ketut Lilik Ayu Sukma Wedha Kristyanti Burhannuddin Burhanuddin, Burhannuddin Cahyana, I Made Dwipa Cok Dewi Widhya Hana Sundari Cok Dewi Widhya HS Cok Dewi Widhya HS Cokorda Dewi Widhya Hana Sundari Desak Gede Dwi Agustini Desak Made Lestari Dewi Dewa Ayu Niti Rahayu Putri Dewi, Kadek Indra Trisna Dewi, Ni Km Ayu Kusuma Dewi, Ni Nyoman Astika Dewi, Ni Putu Ditya Prabandari Dewi, Pande Putu Ayu Patria Dharmawaiswari, Anak Agung Ayu Ratih Dharmawati, I Gst Agung Ayu Dwija, Ida Bagus Nyoman Putra Farsida, Farsida Fusvita Merdekawati Ganjar Noviar Hardiyanta, I Made Yogi Haribaik, Anastaysia Annisa Hasfika, Essydhea Husna, Ismalia I Gusti Agung Ayu Dharmawati I Gusti Agung Ayu Dharmawati I Gusti Agung Dewi Sarihati I Gusti Agung Dewi Sarihati I Gusti Ayu Made Wulan Diantari I Gusti Ayu Sri Dhyanaputri I Gusti Ngurah Teja Pratama I Made Krishna Paramartha I Made Suarjana I Made Suarjana I Made Yogi Hardiyanta I Nyoman Jirna I Nyoman Purna I Wayan Karta I Wayan Karta Ida Ayu Krisna Dwipayanti Ida Ayu Sri Arjani Ida Bagus Oka Suyasa Ida Bagus Oka Suyasa Indriyani Indriyani Jannah Sofy Yanty Kadek Ika Surya Cahyani Kosasih, Audia Nizhma Nabila Kurniawan, Surya Bayu Luh Ade Wilan Krisna Luh Ade Wilankrisna Luh Putu Laksmi Mahastuti, Shri Ayu Purnami Mardhia Mardhia Marpaung, Nurasi Lidya E. Mastra , Nyoman Merdekawati, Fusvita Mochamad Choirul Hadi Ni Kadek Wahyu Diana Sari Ni Komang Erny Astiti Ni Komang Juniawati Ni Komang Omik Trianita Udiana Ni Komang Sri Narayanthi Ni Nyoman Astika Dewi Ni Putu Ditya Prabandari Dewi Ni Putu Ditya Prabandari Dewi Ni Putu Intan Maha Ayu Diyanti Ni Putu Lisa Anjani Ni Putu Yulia Rahma Dewi Ni Wayan Rika Kumara Dewi Noviar, Ganjar Nur Habibah Nur Habibah Nyoman Mastra Posmaningsih, Dewa Ayu Agustini Pradnya Yasa, Ni Putu Candra Dewi Prianggandanni, Made Ayu Vita Purwani Ruth, Grace Monica Putu Amrita Paramahita Putu Diah Wahyuni Rakhmawati, Aprilia Rike Syahniar Rinawati, Luh Putu Rindi, Oktavelendi Dhaneta Graha Rofi'ah, Lisa Khofidatur Ruspawan, I Dewa Made Savitri, Ni Putu Ayu Dani Sofi Yanty, Jannah Sudarmanto, I Gede Sudiadnyana, I Wayan Surya Bayu Kurniawan Suwarriana, I Nyoman Astra Suyasa, Ida Bagus Oka Swastini, I Gusti Agung Ayu Putu Tedja, I Gusti Ayu Wiradari Utami, Luh Mitha Ari Wikantari, Ni Made Ayu Kerti Wilankrisna, Luh Ade Yanty, Jannah Sofy