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All Journal HAYATI Journal of Biosciences MEDIA KONSERVASI Jurnal Ilmu Lingkungan Biotika: Jurnal Ilmiah Biologi Indonesian Journal of Applied Sciences Sosiohumaniora Dharmakarya : Jurnal Aplikasi Ipteks Untuk Masyarakat Jurnal Antropologi: Isu-Isu Sosial budaya Biota Jurnal Kelautan Tropis Pro-Life REINWARDTIA ETNOSIA : Jurnal Etnografi Indonesia UMBARA Indonesian Journal of Anthropology Jurnal Biodjati Chimica et Natura Acta Dinamisia: Jurnal Pengabdian Kepada Masyarakat Biosaintifika: Journal of Biology & Biology Education Agrisocionomics: Jurnal Sosial Ekonomi Pertanian Jurnal BIOEDUIN : Program Studi Pendidikan Biologi Jurnal Kelautan dan Perikanan Terapan (JKPT) Forest and Society Pangadereng : Jurnal Hasil Penelitian Ilmu Sosial dan Humaniora Journal of Tropical Ethnobiology Proceeding Biology Education Conference International Journal of Applied Business and International Management Reinwardtia
Johan Iskandar
Program Studi Biologi, Fakultas Matematika & Ilmu Pengetahuan Alam Universitas Padjadjaran, Jatinangor Sumedang
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences Other

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Journal : Biota

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The Effect of Amphidromus palaceus and Lissachatina fulica land snail mucus on collagen density in white rats (Rattus norvegicus) Pertiwi, Meilisha Putri; Juliandi, Berry; Nurinsiyah, Ayu Savitri; Priawandiputra, Windra; Iskandar, Johan
Biota Vol 11 No 2 (2025): Jurna Biota 2025
Publisher : Faculty of Science and Technology Universitas Islam Negeri Raden Fatah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19109/biota.v11i2.27535

Abstract

Treatment with natural ingredients is essential for healing incision wounds. One promising natural remedy is land snail mucus, which has been used for centuries to address various health conditions, including wounds. This study aimed to evaluate the effects of mucus from Amphidromus palaceus and Lissachatina fulica on collagen density during the healing process of incision wounds in Rattus norvegicus. The in vivo study included 36 rats, divided into four cages with nine rats per cage. Each of rats subjected to approximately 1 cm incision wounds on their backs. The rats were divided into four groups: a negative control group (KN) receiving aquades, a positive control group (KP) treated with 1% bioplacenton, treatment group 1 (P1) receiving 25 µL of A. palaceus mucus, and treatment group 2 (P2) receiving 25 µL of L. fulica mucus. The experiment concluded on days H3, H5, H7, and H10. Histological preparations were made using MT staining to assess collagen density. The results showed both species of snail mucus significantly increased collagen density compared to the negative control (aquades). However, there were no statistically significant differences when comparing L. fulica, A. palaceus, and bioplacenton. Among all the treatment groups, L. fulica mucus (P2) produced the highest collagen density. These findings suggest that both types of snail mucus hold promising potential in promoting the wound healing process.
Co-Authors Achmad Nur Sutikno Agge Ibrati Shabrina Suhanda Agus Widana Aliifah , Felicia Aminuyati Ari Abi Aufa Aseng Ramlan Asep Zainal Mutaqin Aufa, Ari Abi Azhar Ginanjar Azifah An’amillah Bambang Heru Purwanto Berry Juliandi Budi Irawan Budiawati S. Iskandar Budiawati S. Iskandar, Budiawati S. Budiawati Supangkat Budiawati SUpangkat Iskandar, Budiawati SUpangkat Dede Mulyanto Dede Tresna Wiyanti Desak Made Malini Dian Akbarini Diana Budiyanti Eneng Nunuz Rohmatullayaly Faris Muladi Fatimah, Iik Nurul Gunawan, Budhi Hanna Hendriks Herri Y. Hadikusumah Hidayat, Rahmi Aulia Ira Indrawardana Ira Indrawardana Janu Dwi Kristianto Joko Kusmoro JULIATI PRIHATINI Juliati Prihatini Juliati Prihatini Kamilawati, Fitri Madihah Madihah, Madihah Mahesa Elgasani Meilisha Putri Pertiwi Mohamad Nurzaman Muhamad Azahar Bin Abas Muhammad Al Rizky Ratno Budiarto Nia Rossiana Nurinsiyah, Ayu Savitri Nurullia Fitriani Nyayu Siti Aminah Lily Elfrieda Oekan Soekotjo Abdoellah Opan Suhendi Suwartapradja Parikesit Parikesit Rahman Latif Alfian, Rahman Latif Rahmi Aulia Hidayat Ruhyat Partasasmita Ruhyat Pratasasmita Ruly Budiono SATA YOSHIDA SRIE RAHAYU Sidik, Adi Permana Siti Nuraeni Soemarwoto, Rini Sunardi Sunardi Suryana Suryana Susanti Withaningsih Tatang Suharmana Erawan TEGUH HUSODO Tia Setiawati Toni Nuari Tri Dewi Kusumaningrum Pribadi Wawan Hermawan WINDRA PRIAWANDIPUTRA, WINDRA Yayan Suryana Yuli Wahyuni Yustiadi, Taufik